Steven L Alam

Steven L Alam

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Steven L Alam

Steven L Alam

Publications by authors named "Steven L Alam"

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A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability.

Proc Natl Acad Sci U S A 2018 09 4;115(38):E8900-E8908. Epub 2018 Sep 4.

Department of Infectious Diseases, Faculty of Life Sciences and Medicine, King's College London, SE1 9RT London, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1805504115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156662PMC
September 2018

TRIM5α SPRY/coiled-coil interactions optimize avid retroviral capsid recognition.

PLoS Pathog 2017 Oct 17;13(10):e1006686. Epub 2017 Oct 17.

Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville, Virginia, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1006686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667893PMC
October 2017

Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway.

Cell Rep 2016 08 14;16(5):1315-1325. Epub 2016 Jul 14.

Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA 22908, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076470PMC
http://dx.doi.org/10.1016/j.celrep.2016.06.070DOI Listing
August 2016

ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins.

Elife 2015 May 26;4:e06547. Epub 2015 May 26.

Department of Infectious Diseases, King's College London School of Medicine, London, United Kingdom.

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http://dx.doi.org/10.7554/eLife.06547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475061PMC
May 2015

Angiomotin functions in HIV-1 assembly and budding.

Elife 2015 Jan 29;4. Epub 2015 Jan 29.

Department of Biochemistry, University of Utah, Salt Lake City, United States.

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https://elifesciences.org/articles/03778
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http://dx.doi.org/10.7554/eLife.03778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337731PMC
January 2015

Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.

Proc Natl Acad Sci U S A 2014 Dec 17;111(52):18625-30. Epub 2014 Dec 17.

Department of Molecular Physiology and Biological Physics, Center for Membrane Biology, Cardiovascular Research Center, and Division of Cardiovascular Medicine, Department of Medicine, University of Virginia School of Medicine, Charlottesville, VA 22908

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http://dx.doi.org/10.1073/pnas.1419945112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284599PMC
December 2014

Identification of human MVB12 proteins as ESCRT-I subunits that function in HIV budding.

Cell Host Microbe 2007 Jul;2(1):41-53

Department of Biochemistry, University of Utah, Salt Lake City, UT 84112-5650, USA.

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http://dx.doi.org/10.1016/j.chom.2007.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034311PMC
July 2007

Molecular characterization of the Ran-binding zinc finger domain of Nup153.

J Biol Chem 2007 Jun 10;282(23):17090-100. Epub 2007 Apr 10.

Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA.

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http://dx.doi.org/10.1074/jbc.M702715200DOI Listing
June 2007

Structural biology: ESCRT service.

Nature 2007 Jun;447(7147):921-2

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http://dx.doi.org/10.1038/447921aDOI Listing
June 2007

Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain.

Nat Struct Mol Biol 2006 Nov 22;13(11):1029-30. Epub 2006 Oct 22.

Department of Biochemistry, University of Utah, Salt Lake City, Utah 84112-5650, USA.

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http://dx.doi.org/10.1038/nsmb1160DOI Listing
November 2006

The Polycomb-associated protein Rybp is a ubiquitin binding protein.

FEBS Lett 2006 Nov 19;580(26):6233-41. Epub 2006 Oct 19.

Department of Molecular Genetics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Ullmann 809 Bronx, NY 10461, USA.

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http://dx.doi.org/10.1016/j.febslet.2006.10.027DOI Listing
November 2006

Two new structures of Ub-receptor complexes. U2.

Nat Struct Mol Biol 2006 Mar;13(3):186-8

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http://dx.doi.org/10.1038/nsmb0306-186DOI Listing
March 2006

Structure and ESCRT-III protein interactions of the MIT domain of human VPS4A.

Proc Natl Acad Sci U S A 2005 Sep 20;102(39):13813-8. Epub 2005 Sep 20.

Department of Biochemistry, 20 N, 1900 E, University of Utah School of Medicine, Salt Lake City, UT 84132-3201, USA.

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http://dx.doi.org/10.1073/pnas.0502165102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1236530PMC
September 2005

Yeast frataxin solution structure, iron binding, and ferrochelatase interaction.

Biochemistry 2004 Dec;43(51):16254-62

Department of Biochemistry and Molecular Biology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA.

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http://dx.doi.org/10.1021/bi0488193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859087PMC
December 2004

Ubiquitin interactions of NZF zinc fingers.

EMBO J 2004 Apr 18;23(7):1411-21. Epub 2004 Mar 18.

Department of Biochemistry, University of Utah, Salt Lake City, UT, USA.

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http://dx.doi.org/10.1038/sj.emboj.7600114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC391057PMC
April 2004

Structure and ubiquitin binding of the ubiquitin-interacting motif.

J Biol Chem 2003 Aug 14;278(31):28976-84. Epub 2003 May 14.

Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA.

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http://dx.doi.org/10.1074/jbc.M302596200DOI Listing
August 2003

Structure and ubiquitin interactions of the conserved zinc finger domain of Npl4.

J Biol Chem 2003 May 18;278(22):20225-34. Epub 2003 Mar 18.

Department of Biochemistry, University of Utah, Salt Lake City 84132, USA.

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http://dx.doi.org/10.1074/jbc.M300459200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366119PMC
May 2003

Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 protein.

Nat Struct Biol 2002 Nov;9(11):812-7

Department of Biochemistry, University of Utah, Salt Lake City, Utah 84132, USA.

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http://dx.doi.org/10.1038/nsb856DOI Listing
November 2002

Structure and functional interactions of the Tsg101 UEV domain.

EMBO J 2002 May;21(10):2397-406

Department of Biochemistry and Center for Biomolecular Interactions Analysis, University of Utah, Salt Lake City 84132, USA.

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http://emboj.embopress.org/cgi/doi/10.1093/emboj/21.10.2397
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http://dx.doi.org/10.1093/emboj/21.10.2397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC125378PMC
May 2002