Publications by authors named "Steven Kornblau"

100Publications

Targeted therapy in acute myeloid leukemia: current status and new insights from a proteomic perspective.

Expert Rev Proteomics 2020 01 23;17(1):1-10. Epub 2020 Jan 23.

Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14789450.2020.1717951DOI Listing
January 2020

Antibody Screening.

Adv Exp Med Biol 2019 ;1188:149-163

Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-981-32-9755-5_8DOI Listing
December 2019

Peptide microarray of pediatric acute myeloid leukemia is related to relapse and reveals involvement of DNA damage response and repair.

Oncotarget 2019 Jul 23;10(45):4679-4690. Epub 2019 Jul 23.

Department of Pediatric Oncology/Hematology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.27086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659796PMC
July 2019

LGALS3 is connected to CD74 in a previously unknown protein network that is associated with poor survival in patients with AML.

EBioMedicine 2019 Jun 16;44:126-137. Epub 2019 May 16.

Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX, USA; Division of Molecular Hematology and Therapy, University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2019.05.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604360PMC
June 2019

Proteomic Profiling of Acute Promyelocytic Leukemia Identifies Two Protein Signatures Associated with Relapse.

Proteomics Clin Appl 2019 07 4;13(4):e1800133. Epub 2019 Feb 4.

Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030-4009, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/prca.201800133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635093PMC
July 2019

Myeloid malignancies with somatic mutations can be associated with an immunodeficiency phenotype.

Leuk Lymphoma 2019 08 16;60(8):2025-2033. Epub 2019 Jan 16.

a Department of Leukemia , The University of Texas MD Anderson Cancer Center , Houston , TX , USA.

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/10428194.2018.1
Publisher Site
http://dx.doi.org/10.1080/10428194.2018.1551535DOI Listing
August 2019

Nivolumab-induced encephalitis post allogeneic stem cell transplant in a patient with Hodgkin's disease.

Bone Marrow Transplant 2019 05 15;54(5):749-751. Epub 2018 Oct 15.

Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41409-018-0363-6DOI Listing
May 2019

Mutant NPM1 Maintains the Leukemic State through HOX Expression.

Cancer Cell 2018 09;34(3):499-512.e9

Stem Cell and Regenerative Medicine, Baylor College of Medicine, Houston, TX 77030, USA; Center for Cell and Gene Therapy, Texas Children's Hospital and Houston Methodist Hospital, Baylor College of Medicine, Houston, TX 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2018.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159911PMC
September 2018

Mycoplasma contamination of leukemic cell lines alters protein expression determined by reverse phase protein arrays.

Cytotechnology 2018 Dec 6;70(6):1529-1535. Epub 2018 Sep 6.

Department of Leukemia, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Box 448, Houston, TX, 77030-4009, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10616-018-0244-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269355PMC
December 2018

VEGFC Antibody Therapy Drives Differentiation of AML.

Cancer Res 2018 10 5;78(20):5940-5948. Epub 2018 Sep 5.

Division of Pediatric Oncology/Hematology, Department of Pediatrics, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-18-0250DOI Listing
October 2018

Shining a light on cell signaling in leukemia through proteomics: relevance for the clinic.

Expert Rev Proteomics 2018 07 6;15(7):613-622. Epub 2018 Jul 6.

d Department of Leukemia , The University of Texas M.D. Anderson Cancer Center , Houston , TX , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14789450.2018.1487781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444923PMC
July 2018

Decomposing the Apoptosis Pathway Into Biologically Interpretable Principal Components.

Cancer Inform 2018 9;17:1176935118771082. Epub 2018 May 9.

Department of Biomedical Informatics, The Ohio State University, Columbus, OH, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1176935118771082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987987PMC
May 2018

Recurrent Patterns of Protein Expression Signatures in Pediatric Acute Lymphoblastic Leukemia: Recognition and Therapeutic Guidance.

Mol Cancer Res 2018 08 18;16(8):1263-1274. Epub 2018 Apr 18.

Department of Pediatrics, Baylor College of Medicine/Dan L. Duncan Cancer Center and Texas Children's Cancer Center, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-17-0730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496939PMC
August 2018

Integrative analysis reveals functional and regulatory roles of H3K79me2 in mediating alternative splicing.

Genome Med 2018 04 17;10(1):30. Epub 2018 Apr 17.

Department of Molecular Medicine, University of Texas Health, 8403 Floyd Curl, San Antonio, TX, 78229, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13073-018-0538-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902843PMC
April 2018

Role of MSC-derived galectin 3 in the AML microenvironment.

Biochim Biophys Acta Mol Cell Res 2018 07 12;1865(7):959-969. Epub 2018 Apr 12.

Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX, United States; Section of Molecular Hematology, University of Texas MD Anderson Cancer Center, Houston, TX, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbamcr.2018.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936474PMC
July 2018

Histone Modification Patterns Using RPPA-Based Profiling Predict Outcome in Acute Myeloid Leukemia Patients.

Proteomics 2018 04 2;18(8):e1700379. Epub 2018 Apr 2.

Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/pmic.201700379
Publisher Site
http://dx.doi.org/10.1002/pmic.201700379DOI Listing
April 2018

Necrotizing fungal gingivitis in a patient with Acute Myelogenous Leukemia: visible yet obscure.

J Oral Maxillofac Surg Med Pathol 2018 Jan 12;30(1):50-54. Epub 2017 Sep 12.

Department of Leukemia, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajoms.2017.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796543PMC
January 2018

p53 pathway dysfunction in AML: beyond mutations.

Oncotarget 2017 Dec 27;8(65):108288-108289. Epub 2017 Nov 27.

Alfonso Quintás-Cardama: TCR2 Therapeutics, Cambridge, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.22713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752443PMC
December 2017

Thresher: determining the number of clusters while removing outliers.

BMC Bioinformatics 2018 01 8;19(1). Epub 2018 Jan 8.

Department of Biomedical Informatics, The Ohio State University, 250 Lincoln Tower, 1800 Cannon Drive, Columbus, 43210, OH, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12859-017-1998-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759208PMC
January 2018

Tumor status and genotype affect the bone marrow microenvironment in acute myeloid leukemia.

Oncotarget 2017 Oct 6;8(48):83354-83369. Epub 2017 Jul 6.

Department of Leukemia, Section of Molecular Hematology and Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.19042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663521PMC
October 2017

Focal Adhesion Kinase as a Potential Target in AML and MDS.

Mol Cancer Ther 2017 06 7;16(6):1133-1144. Epub 2017 Mar 7.

Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-16-0719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457713PMC
June 2017

Low expression of ASH2L protein correlates with a favorable outcome in acute myeloid leukemia.

Leuk Lymphoma 2017 05 13;58(5):1207-1218. Epub 2016 Oct 13.

c Division of Molecular Hematology, Department of Leukemia , The University of Texas MD Anderson Cancer Center , Houston , TX , USA.

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/10428194.2016.1
Publisher Site
http://dx.doi.org/10.1080/10428194.2016.1235272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994918PMC
May 2017

Evolution-informed modeling improves outcome prediction for cancers.

Evol Appl 2017 Jan 21;10(1):68-76. Epub 2016 Oct 21.

Department of Computational Medicine and Bioinformatics University of Michigan Ann Arbor MI USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/eva.12417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192825PMC
January 2017

Targeting FLT3-ITD signaling mediates ceramide-dependent mitophagy and attenuates drug resistance in AML.

Blood 2016 10 18;128(15):1944-1958. Epub 2016 Aug 18.

Department of Biochemistry and Molecular Biology and Hollings Cancer Center, Medical University of South Carolina, Charleston, SC; and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2016-04-708750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064718PMC
October 2016

Epidermal growth factor receptor is expressed and active in a subset of acute myeloid leukemia.

J Hematol Oncol 2016 08 3;9(1):64. Epub 2016 Aug 3.

Department of Pediatrics, Division of Pediatric Oncology/Hematology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13045-016-0294-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971659PMC
August 2016

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Authors:
Elizabeth C Townsend Mark A Murakami Alexandra Christodoulou Amanda L Christie Johannes Köster Tiffany A DeSouza Elizabeth A Morgan Scott P Kallgren Huiyun Liu Shuo-Chieh Wu Olivia Plana Joan Montero Kristen E Stevenson Prakash Rao Raga Vadhi Michael Andreeff Philippe Armand Karen K Ballen Patrizia Barzaghi-Rinaudo Sarah Cahill Rachael A Clark Vesselina G Cooke Matthew S Davids Daniel J DeAngelo David M Dorfman Hilary Eaton Benjamin L Ebert Julia Etchin Brant Firestone David C Fisher Arnold S Freedman Ilene A Galinsky Hui Gao Jacqueline S Garcia Francine Garnache-Ottou Timothy A Graubert Alejandro Gutierrez Ensar Halilovic Marian H Harris Zachary T Herbert Steven M Horwitz Giorgio Inghirami Andrew M Intlekofer Moriko Ito Shai Izraeli Eric D Jacobsen Caron A Jacobson Sébastien Jeay Irmela Jeremias Michelle A Kelliher Raphael Koch Marina Konopleva Nadja Kopp Steven M Kornblau Andrew L Kung Thomas S Kupper Nicole R LeBoeuf Ann S LaCasce Emma Lees Loretta S Li A Thomas Look Masato Murakami Markus Muschen Donna Neuberg Samuel Y Ng Oreofe O Odejide Stuart H Orkin Rachel R Paquette Andrew E Place Justine E Roderick Jeremy A Ryan Stephen E Sallan Brent Shoji Lewis B Silverman Robert J Soiffer David P Steensma Kimberly Stegmaier Richard M Stone Jerome Tamburini Aaron R Thorner Paul van Hummelen Martha Wadleigh Marion Wiesmann Andrew P Weng Jens U Wuerthner David A Williams Bruce M Wollison Andrew A Lane Anthony Letai Monica M Bertagnolli Jerome Ritz Myles Brown Henry Long Jon C Aster Margaret A Shipp James D Griffin David M Weinstock

Cancer Cell 2016 07 11;30(1):183. Epub 2016 Jul 11.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2016.06.008DOI Listing
July 2016

DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia.

Blood 2016 08 22;128(7):971-81. Epub 2016 Jun 22.

Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, TX; Dan L. Duncan Cancer Center, Department of Molecular and Human Genetics, Stem Cells and Regenerative Medicine Center, and Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX;

View Article

Download full-text PDF

Source
http://www.bloodjournal.org/content/bloodjournal/early/2016/
Web Search
http://www.bloodjournal.org/cgi/doi/10.1182/blood-2015-11-68
Publisher Site
http://dx.doi.org/10.1182/blood-2015-11-684225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990856PMC
August 2016

Mixed-phenotype acute leukemia (MPAL) exhibits frequent mutations in DNMT3A and activated signaling genes.

Exp Hematol 2016 08 18;44(8):740-4. Epub 2016 May 18.

Cancer and Hematology Centers, Texas Children's Hospital/Baylor College of Medicine, Houston, TX. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exphem.2016.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956537PMC
August 2016

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Authors:
Elizabeth C Townsend Mark A Murakami Alexandra Christodoulou Amanda L Christie Johannes Köster Tiffany A DeSouza Elizabeth A Morgan Scott P Kallgren Huiyun Liu Shuo-Chieh Wu Olivia Plana Joan Montero Kristen E Stevenson Prakash Rao Raga Vadhi Michael Andreeff Philippe Armand Karen K Ballen Patrizia Barzaghi-Rinaudo Sarah Cahill Rachael A Clark Vesselina G Cooke Matthew S Davids Daniel J DeAngelo David M Dorfman Hilary Eaton Benjamin L Ebert Julia Etchin Brant Firestone David C Fisher Arnold S Freedman Ilene A Galinsky Hui Gao Jacqueline S Garcia Francine Garnache-Ottou Timothy A Graubert Alejandro Gutierrez Ensar Halilovic Marian H Harris Zachary T Herbert Steven M Horwitz Giorgio Inghirami Andrew M Intlekofer Moriko Ito Shai Izraeli Eric D Jacobsen Caron A Jacobson Sébastien Jeay Irmela Jeremias Michelle A Kelliher Raphael Koch Marina Konopleva Nadja Kopp Steven M Kornblau Andrew L Kung Thomas S Kupper Nicole R LeBoeuf Ann S LaCasce Emma Lees Loretta S Li A Thomas Look Masato Murakami Markus Muschen Donna Neuberg Samuel Y Ng Oreofe O Odejide Stuart H Orkin Rachel R Paquette Andrew E Place Justine E Roderick Jeremy A Ryan Stephen E Sallan Brent Shoji Lewis B Silverman Robert J Soiffer David P Steensma Kimberly Stegmaier Richard M Stone Jerome Tamburini Aaron R Thorner Paul van Hummelen Martha Wadleigh Marion Wiesmann Andrew P Weng Jens U Wuerthner David A Williams Bruce M Wollison Andrew A Lane Anthony Letai Monica M Bertagnolli Jerome Ritz Myles Brown Henry Long Jon C Aster Margaret A Shipp James D Griffin David M Weinstock

Cancer Cell 2016 04;29(4):574-586

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, 450 Brookline Avenue, Dana 510B, MA 02215, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2016.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177991PMC
April 2016

Hypomethylation of TET2 Target Genes Identifies a Curable Subset of Acute Myeloid Leukemia.

J Natl Cancer Inst 2015 Nov 13;108(2). Epub 2015 Nov 13.

Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia, PA (JY, JJ, NJMR, MC, JPJI); Department of Leukemia (JY, RT, JJ, NJMR, SAP, SMK, FR, HMK, JPJI) and Department of Hematopathology (CEBR), The University of Texas MD Anderson Cancer Center, Houston, TX.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djv323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862435PMC
November 2015

Progeny Clustering: A Method to Identify Biological Phenotypes.

Sci Rep 2015 Aug 12;5:12894. Epub 2015 Aug 12.

Department of Bioengineering, Rice University.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep12894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533525PMC
August 2015

PKR inhibits the DNA damage response, and is associated with poor survival in AML and accelerated leukemia in NHD13 mice.

Blood 2015 Sep 22;126(13):1585-94. Epub 2015 Jul 22.

Department of Medicine, Division of Hematology and Oncology, Department of Medicine, University of Florida, Gainesville, FL; and University of Florida Health Cancer Center, Gainesville, FL;

View Article

Download full-text PDF

Source
http://www.bloodjournal.org/content/126/13/1585.full.pdf
Web Search
http://www.bloodjournal.org/content/early/2015/07/22/blood-2
Web Search
http://www.bloodjournal.org/cgi/doi/10.1182/blood-2015-03-63
Publisher Site
http://dx.doi.org/10.1182/blood-2015-03-635227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582335PMC
September 2015

Essential role for cyclic-AMP responsive element binding protein 1 (CREB) in the survival of acute lymphoblastic leukemia.

Oncotarget 2015 Jun;6(17):14970-81

Division of Pediatric Oncology/Hematology, Department of Pediatrics, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558129PMC
http://dx.doi.org/10.18632/oncotarget.3911DOI Listing
June 2015