Publications by authors named "Steven Joffe"

98Publications

Emergency Approvals for COVID-19: Evolving Impact on Obligations to Patients in Clinical Care and Research.

Ann Intern Med 2020 Nov 3. Epub 2020 Nov 3.

University of Pennsylvania and Children's Hospital of Philadelphia, Philadelphia, Pennsylvania (S.J.).

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http://dx.doi.org/10.7326/M20-6703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643168PMC
November 2020

Rethinking ethical oversight in the era of the learning health system.

Healthc (Amst) 2020 Dec 25;8(4):100462. Epub 2020 Aug 25.

Harvard Medical School, Boston, MA, USA; Harvard Pilgrim Health Care Institute, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.hjdsi.2020.100462DOI Listing
December 2020

Regulatory flexibility for COVID-19 research.

J Law Biosci 2020 Jan-Jun;7(1):lsaa057. Epub 2020 Jul 7.

Department of Medical Ethics and Health Policy, Perelman School of Medicine, Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1093/jlb/lsaa057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7454723PMC
July 2020

COVID-19 Moves Medicine into a Virtual Space: A Paradigm Shift From Touch to Talk to Establish Trust.

Ann Surg 2020 08;272(2):e159-e160

Department of Surgery, Center for Surgery and Health Economics, Hospital of the University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1097/SLA.0000000000004098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268874PMC
August 2020

Ethical and Regulatory Issues for Embedded Pragmatic Trials Involving People Living with Dementia.

J Am Geriatr Soc 2020 Jul;68 Suppl 2:S37-S42

Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1111/jgs.16620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323902PMC
July 2020

The Importance of Engaging Children in Research Decision-Making: A Preliminary Mixed-Methods Study.

Ethics Hum Res 2020 05;42(3):12-20

The interim chair in the Department of Medical Ethics and Health Policy and the Founders professor of medical ethics and health policy at the University of Pennsylvania Perelman School of Medicine.

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http://dx.doi.org/10.1002/eahr.500049DOI Listing
May 2020

Ethics and Resource Scarcity: ASCO Recommendations for the Oncology Community During the COVID-19 Pandemic.

J Clin Oncol 2020 07 28;38(19):2201-2205. Epub 2020 Apr 28.

The University of Chicago, Chicago, IL.

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http://dx.doi.org/10.1200/JCO.20.00960DOI Listing
July 2020

Sharing Patient Data Without Exploiting Patients.

JAMA 2020 Feb;323(6):505-506

Perelman School of Medicine, Department of Medical Ethics and Health Policy, University of Pennsylvania.

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http://dx.doi.org/10.1001/jama.2019.22354DOI Listing
February 2020

Pay-to-Participate Trials and Vulnerabilities in Research Ethics Oversight.

JAMA 2019 Sep 23. Epub 2019 Sep 23.

Department of Medical Ethics and Health Policy, Perelman School of Medicine, and Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1001/jama.2019.14703DOI Listing
September 2019

Paying Clinical Trial Participants: Legal Risks and Mitigation Strategies.

J Clin Oncol 2020 02 14;38(6):532-537. Epub 2019 Jun 14.

University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1200/JCO.19.00250DOI Listing
February 2020

Response to Open Peer Commentaries: When Is It Ethical for Physician-Investigators to Seek Consent From Their Own Patients?

Am J Bioeth 2019 05;19(5):W3-W4

c University of Pennsylvania Perelman School of Medicine.

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http://dx.doi.org/10.1080/15265161.2019.1591543DOI Listing
May 2019

Patient-Physician Relationship in the Age of Expanded Access to Information-Reply.

JAMA 2019 04;321(16):1633-1634

Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia.

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http://dx.doi.org/10.1001/jama.2019.1073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012316PMC
April 2019

When Is It Ethical for Physician-Investigators to Seek Consent From Their Own Patients?

Am J Bioeth 2019 Apr;19(4):11-18

c University of Pennsylvania Perelman School of Medicine; Leonard Davis Institute of Health Economics.

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https://www.tandfonline.com/doi/full/10.1080/15265161.2019.1
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http://dx.doi.org/10.1080/15265161.2019.1572811DOI Listing
April 2019

When Is It Ethical for Physician-Investigators to Seek Consent From Their Own Patients?

Am J Bioeth 2019 Apr;19(4):11-18

c University of Pennsylvania Perelman School of Medicine; Leonard Davis Institute of Health Economics.

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https://www.tandfonline.com/doi/full/10.1080/15265161.2019.1
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http://dx.doi.org/10.1080/15265161.2019.1572811DOI Listing
April 2019

The Multidimensional Illness Severity Questionnaire: Preliminary evaluation of a brief parent-reported measure of illness severity.

J Paediatr Child Health 2019 Oct 5;55(10):1241-1246. Epub 2019 Feb 5.

Department of Medical Ethics and Health Policy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States.

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http://dx.doi.org/10.1111/jpc.14391DOI Listing
October 2019

Association Between Financial Incentives and Participant Deception About Study Eligibility.

JAMA Netw Open 2019 01 4;2(1):e187355. Epub 2019 Jan 4.

Department of Medical Ethics and Health Policy, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1001/jamanetworkopen.2018.7355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484547PMC
January 2019

Protecting clinical trial participants and study integrity in the age of social media.

Cancer 2018 12 17;124(24):4610-4617. Epub 2018 Oct 17.

Division of Hematology-Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

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http://doi.wiley.com/10.1002/cncr.31748
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http://dx.doi.org/10.1002/cncr.31748DOI Listing
December 2018

The New Age of Patient Autonomy: Implications for the Patient-Physician Relationship.

JAMA 2018 11;320(19):1973-1974

Department of Medical Ethics and Health Policy, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.20
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http://dx.doi.org/10.1001/jama.2018.14382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988779PMC
November 2018

Informed Consent and the Role of the Treating Physician.

N Engl J Med 2018 10;379(15):e25

University of Pennsylvania, Philadelphia, PA

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http://dx.doi.org/10.1056/NEJMc1809629DOI Listing
October 2018

Will my child do better if she enrolls in a clinical trial?

Cancer 2018 10 6;124(20):3965-3968. Epub 2018 Oct 6.

Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

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http://doi.wiley.com/10.1002/cncr.31722
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http://dx.doi.org/10.1002/cncr.31722DOI Listing
October 2018

Will my child do better if she enrolls in a clinical trial?

Cancer 2018 10 6;124(20):3965-3968. Epub 2018 Oct 6.

Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

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http://doi.wiley.com/10.1002/cncr.31722
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http://dx.doi.org/10.1002/cncr.31722DOI Listing
October 2018

Addressing Financial Barriers to Patient Participation in Clinical Trials: ASCO Policy Statement.

J Clin Oncol 2018 Sep 13:JCO1801132. Epub 2018 Sep 13.

Karen M. Winkfield, Wake Forest Baptist Medical Center, Winston-Salem, NC; Jonathan K. Phillips and Dana S. Wollins, American Society of Clinical Oncology, Alexandria, VA; Steven Joffe, University of Pennsylvania Perelman School of Medicine; Michael T. Halpern, Temple University, Philadelphia, PA; and Beverly Moy, Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.1200/JCO.18.01132DOI Listing
September 2018

Informed Consent and the Role of the Treating Physician.

N Engl J Med 2018 Jun;378(25):2433-2438

From the Department of Medical Ethics and Health Policy, Perelman School of Medicine (H.F.L., S.J., E.A.F.), and the Leonard Davis Institute of Health Economics (H.F.L., S.J.), University of Pennsylvania, Children's Hospital of Philadelphia (S.J.), and University of Pennsylvania Law School (E.A.F.) - all in Philadelphia.

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http://dx.doi.org/10.1056/NEJMhle1800071DOI Listing
June 2018

Ethics and the Underreporting of Research Biopsy Findings in Clinical Trials.

JAMA Oncol 2018 08;4(8):1041-1042

Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Division of Oncology, Children's Hospital of Philadelphia, Philadelphia.

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http://dx.doi.org/10.1001/jamaoncol.2018.1002DOI Listing
August 2018

Three Steps Toward a More Sustainable Path for Targeted Cancer Drugs.

JAMA 2018 06;319(21):2167-2168

Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1001/jama.2018.3414DOI Listing
June 2018

Characteristics Associated With Preferences for Parent-Centered Decision Making in Neonatal Intensive Care.

JAMA Pediatr 2018 05;172(5):461-468

Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia.

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http://dx.doi.org/10.1001/jamapediatrics.2017.5776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875325PMC
May 2018

Gender and Byline Placement of Co-first Authors in Clinical and Basic Science Journals With High Impact Factors.

JAMA 2018 02;319(6):610-611

Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia.

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http://dx.doi.org/10.1001/jama.2017.18672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838607PMC
February 2018

The benefit sharing vision of H3Africa.

Dev World Bioeth 2018 Jun 15;18(2):165-170. Epub 2018 Feb 15.

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http://dx.doi.org/10.1111/dewb.12185DOI Listing
June 2018

Federal Right-to-Try Legislation - Threatening the FDA's Public Health Mission.

N Engl J Med 2018 Feb 10;378(8):695-697. Epub 2018 Jan 10.

From the Department of Medical Ethics and Health Policy, Perelman School of Medicine, and the Leonard Davis Institute of Health Economics, University of Pennsylvania (S.J., H.F.L.), and the Children's Hospital of Philadelphia (S.J.) - all in Philadelphia.

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http://dx.doi.org/10.1056/NEJMp1714054DOI Listing
February 2018

Justification and authority in institutional review board decision letters.

Soc Sci Med 2017 12 16;194:25-33. Epub 2017 Oct 16.

Department of Medical Ethics and Health Policy, Blockley Hall 14th Floor, Perelman School of Medicine, University of Pennsylvania, 423 Guardian Drive, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.socscimed.2017.10.013DOI Listing
December 2017

Ethical considerations in genomic testing for hematologic disorders.

Blood 2017 07 9;130(4):460-465. Epub 2017 Jun 9.

Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.1182/blood-2017-01-734558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533200PMC
July 2017

From Sequence Data to Returnable Results: Ethical Issues in Variant Calling and Interpretation.

Genet Test Mol Biomarkers 2017 Mar 16;21(3):178-183. Epub 2017 Feb 16.

4 Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1089/gtmb.2016.0413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367907PMC
March 2017

Justifying Clinical Nudges.

Hastings Cent Rep 2017 Mar;47(2):32-38

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http://dx.doi.org/10.1002/hast.688DOI Listing
March 2017

Patient Advocacy Organizations, Industry Funding, and Conflicts of Interest.

JAMA Intern Med 2017 03;177(3):344-350

Department of Medical Ethics & Health Policy, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1001/jamainternmed.2016.8443DOI Listing
March 2017

A taxonomy of medical uncertainties in clinical genome sequencing.

Genet Med 2017 08 19;19(8):918-925. Epub 2017 Jan 19.

Social and Behavioral Research Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/gim.2016.212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517355PMC
August 2017

Biomarker-Defined Subsets of Common Diseases: Policy and Economic Implications of Orphan Drug Act Coverage.

PLoS Med 2017 Jan 3;14(1):e1002190. Epub 2017 Jan 3.

Department of Medical Ethics & Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.1002190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207392PMC
January 2017

Ethics knowledge of recent paediatric residency graduates: the role of residency ethics curricula.

J Med Ethics 2016 12 19;42(12):809-814. Epub 2016 Oct 19.

Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1136/medethics-2016-103625DOI Listing
December 2016

Patient and Physician Views about Protocolized Dialysis Treatment in Randomized Trials and Clinical Care.

AJOB Empir Bioeth 2016 23;7(2):106-115. Epub 2015 Oct 23.

Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania; Department of Medicine, University of Pennsylvania; Department of Medical Ethics and Health Policy, University of Pennsylvania; Leonard Davis Institute of Health Economics Center for Health Incentives and Behavioral Economics, at the Perelman School of Medicine, University of Pennsylvania; Department of Biostatistics and Epidemiology.

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http://dx.doi.org/10.1080/23294515.2015.1111272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098473PMC
January 2018

Parental Decision-Making Preferences in Neonatal Intensive Care.

J Pediatr 2016 12 21;179:36-41.e3. Epub 2016 Sep 21.

Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA; Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, PA. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2016.08.030DOI Listing
December 2016

The Ethics of Infection Challenges in Primates.

Hastings Cent Rep 2016 07 21;46(4):20-6. Epub 2016 Mar 21.

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http://dx.doi.org/10.1002/hast.580DOI Listing
July 2016

Procedure-specific consent is the norm in United States intensive care units.

Intensive Care Med 2016 Oct 14;42(10):1637-1638. Epub 2016 Jul 14.

Leonard Davis Institute of Health Economics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/s00134-016-4433-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035197PMC
October 2016

Clinical Trials Infrastructure as a Quality Improvement Intervention in Low- and Middle-Income Countries.

Am J Bioeth 2016 06;16(6):3-11

c University of Pennsylvania Perelman School of Medicine.

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http://dx.doi.org/10.1080/15265161.2016.1170230DOI Listing
June 2016

A Flawed Revision of the Common Rule.

Ann Intern Med 2016 Jul 5;165(2):143-4. Epub 2016 Apr 5.

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http://dx.doi.org/10.7326/M16-0119DOI Listing
July 2016

An Ethical Framework for Allocating Scarce Life-Saving Chemotherapy and Supportive Care Drugs for Childhood Cancer.

J Natl Cancer Inst 2016 Jun 29;108(6):djv392. Epub 2016 Jan 29.

Division of Pediatric Hematology/Oncology, The Herman and Walter Samuelson Children's Hospital at Sinai, Baltimore, MD (YU); Johns Hopkins University, Berman Institute of Bioethics, Baltimore, MD (YU); IWK Health Centre, Departments of Pediatrics and Bioethics, Dalhousie University, Halifax, Nova Scotia, Canada (CVF); Texas Children's Hospital, Houston, TX (BB); Texas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX (SB); Division of Pediatric Hematology/Oncology/Stem Cell Transplant, Lucile Packard Children's Hospital, Stanford Palo Alto, CA (KPG); University of Iowa, Iowa City, IA (CW); Department of Medical Ethics & Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA (SJ).

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http://dx.doi.org/10.1093/jnci/djv392DOI Listing
June 2016

Physicians and Insider Trading.

JAMA Intern Med 2015 Dec;175(12):1955-9

Department of Medical Ethics & Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia.

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http://dx.doi.org/10.1001/jamainternmed.2015.5610DOI Listing
December 2015

Gatekeepers for pragmatic clinical trials.

Clin Trials 2015 Oct 15;12(5):442-8. Epub 2015 Sep 15.

Department of Medical Ethics and Health Policy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1177/1740774515597699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592478PMC
October 2015

Professionally Responsible Disclosure of Genomic Sequencing Results in Pediatric Practice.

Pediatrics 2015 Oct 14;136(4):e974-82. Epub 2015 Sep 14.

Department of Pediatrics, University of Washington, Seattle, Washington.

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http://dx.doi.org/10.1542/peds.2015-0624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586726PMC
October 2015

Institutional Oversight of Faculty-Industry Consulting Relationships in U.S. Medical Schools: A Delphi Study.

J Law Med Ethics 2015 ;43(2):383-96

Professor of Law at Stanford Law School and a Professor of Health Research and Policy at Stanford School of Medicine. She received her J.D. from Yale Law School in New Haven, CT, a Ph.D. in Health Policy and Administration from the University of North Carolina at Chapel Hill, and an M.Phil. in Comparative Social Research from Oxford University in Oxford, UK. At the time of this research, she was a Professor of Law and Public Health in the Department of Health Policy and Management at the Harvard School of Public Health.

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http://dx.doi.org/10.1111/jlme.12255DOI Listing
December 2016

Clinical research: Should patients pay to play?

Sci Transl Med 2015 Jul;7(298):298ps16

Department of Philosophy, Stanford University, Stanford, CA 94305-2155, USA.

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http://dx.doi.org/10.1126/scitranslmed.aac5204DOI Listing
July 2015

Promoting Informed Decision Making for Comparative Effectiveness Randomized Trials.

JAMA Pediatr 2015 Sep;169(9):803-4

Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia4Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1001/jamapediatrics.2015.0906DOI Listing
September 2015

IRB practices and policies regarding the secondary research use of biospecimens.

BMC Med Ethics 2015 May 8;16:32. Epub 2015 May 8.

Department of Bioethics, TA212 School of Medicine, Case Western Reserve University, 10900 Euclid Ave., Cleveland, OH, 44106, USA.

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http://dx.doi.org/10.1186/s12910-015-0020-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426182PMC
May 2015

Reply to S. Gupta et al.

J Clin Oncol 2015 Apr 23;33(12):1414. Epub 2015 Feb 23.

National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1200/JCO.2014.60.1096DOI Listing
April 2015

Commentary on Hey and Kimmelman.

Clin Trials 2015 Apr 3;12(2):116-8. Epub 2015 Feb 3.

Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1177/1740774515568917DOI Listing
April 2015

Actionable exomic incidental findings in 6503 participants: challenges of variant classification.

Genome Res 2015 Mar 30;25(3):305-15. Epub 2015 Jan 30.

Department of Medicine, Division of Medical Genetics, University of Washington, Seattle, Washington 98195, USA; Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA;

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http://dx.doi.org/10.1101/gr.183483.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352885PMC
March 2015

Ethical testing of experimental ebola treatments--reply.

Authors:
Steven Joffe

JAMA 2015 Jan;313(4):422

Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia.

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http://dx.doi.org/10.1001/jama.2014.17262DOI Listing
January 2015

Generalizability of trial results to elderly Medicare patients with advanced solid tumors (Alliance 70802).

J Natl Cancer Inst 2015 Jan 27;107(1):336. Epub 2014 Nov 27.

Massachusetts General Hospital Cancer Center, Boston, MA (EL); Departments of Medicine, and Health Care Policy, Harvard Medical School, Boston, MA (EL, YH, AM); American Society of Clinical Oncology, Alexandria, VA (RLS); Department of Medicine, University of North Carolina, Chapel Hill, NC (HM); Department of Medicine, Duke University, Durham, NC (HJC); City of Hope, Duarte, CA (AH); Department of Medicine, University of Chicago, Chicago, IL (HLK); Department of Medicine, University of California San Francisco, San Francisco, CA (AV); Yale Cancer Center, New Haven, CT (RL); Department of Medicine, the University of Tennessee, Memphis, TN (HN); Department of Medicine, Ohio State University, Columbus, OH (RMG); Department of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA (SJ).

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http://dx.doi.org/10.1093/jnci/dju336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271075PMC
January 2015

Predictors of clinical trial data sharing: exploratory analysis of a cross-sectional survey.

Trials 2014 Oct 2;15:384. Epub 2014 Oct 2.

Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, 1 Church Street, Suite 200, New Haven, CT 06510, USA.

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http://dx.doi.org/10.1186/1745-6215-15-384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192345PMC
October 2014

The challenge of informed consent and return of results in translational genomics: empirical analysis and recommendations.

J Law Med Ethics 2014 ;42(3):344-55

Professor and the Chair of Social Medicine in the School of Medicine and an Adjunct Professor of Sociology at the University of North Carolina at Chapel Hill.

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http://dx.doi.org/10.1111/jlme.12151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262925PMC
November 2016

Chemotherapy parity laws: a remedy for high drug costs?

JAMA Intern Med 2014 Nov;174(11):1721-2

Program on Regulation, Therapeutics, and Law (PORTAL), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamainternmed.2014.4878DOI Listing
November 2014

Evaluating novel therapies during the Ebola epidemic.

Authors:
Steven Joffe

JAMA 2014 Oct;312(13):1299-300

Department of Medical Ethics and Health Policy, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1001/jama.2014.12867DOI Listing
October 2014

Ethics of cancer clinical trials in low-resource settings.

J Clin Oncol 2014 Oct 2;32(28):3192-6. Epub 2014 Sep 2.

Steven Joffe, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; and Franklin G. Miller, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1200/JCO.2014.56.9780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171362PMC
October 2014

A systematic review of state and manufacturer physician payment disclosure websites: implications for implementation of the Sunshine Act.

J Law Med Ethics 2014 ;42(2):208-19

Candidate in Health Policy at Harvard Medical School (Boston, MA) and the Graduate School of Arts and Sciences, Harvard University (Cambridge, MA).

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http://dx.doi.org/10.1111/jlme.12136DOI Listing
July 2016

Determining minimal risk for comparative effectiveness research.

IRB 2014 May-Jun;36(3):16-8

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July 2014

Are hybrid umbilical cord blood banks really the best of both worlds?

J Med Ethics 2015 Mar 13;41(3):272-5. Epub 2014 May 13.

Department of Medical Ethics and Health Policy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1136/medethics-2013-101673DOI Listing
March 2015

Survival improvements in adolescents and young adults after myeloablative allogeneic transplantation for acute lymphoblastic leukemia.

Biol Blood Marrow Transplant 2014 Jun 7;20(6):829-36. Epub 2014 Mar 7.

Center for International Blood and Marrow Transplant Research, Minneapolis, Minnesota; Blood and Marrow Transplant Program, Cleveland Clinic, Cleveland, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2014.02.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019683PMC
June 2014

Chemotherapy drug shortages in pediatric oncology: a consensus statement.

Pediatrics 2014 Mar 2;133(3):e716-24. Epub 2014 Feb 2.

Johns Hopkins Berman Institute of Bioethics, Baltimore, Maryland;

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http://dx.doi.org/10.1542/peds.2013-2946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934344PMC
March 2014

Communicating about prognosis: ethical responsibilities of pediatricians and parents.

Pediatrics 2014 Feb;133 Suppl 1:S24-30

Department of Pediatric Oncology and the Center for Population Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts;

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http://dx.doi.org/10.1542/peds.2013-3608EDOI Listing
February 2014

Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease.

N Engl J Med 2014 Jan;370(4):311-21

From the Alzheimer's Disease and Memory Disorders Center, Department of Neurology, Baylor College of Medicine, Houston (R.S.D.); Alzheimer's Disease Cooperative Study, Department of Family and Preventive Medicine (R.G.T., R.R., X.S.), and the Department of Neurosciences (R.G.T., R.R., P.S.A., R.M.), University of California at San Diego, San Diego; Indiana Alzheimer Disease Center, Indiana University (M.F.), and Eli Lilly (E.S., H.L.-S., R.M.) - both in Indianapolis; the Department of Neuropathology, School of Medicine, and the Department of Neuropathology and Neuroscience, School of Pharmacological Science, University of Tokyo, Tokyo (T.I.); Gerontopole, Unité Mixte de Recherche 1027, Centre Hospitalier Universitaire Toulouse, Toulouse, France (B.V.); the Department of Medical Ethics and Health Policy, University of Pennsylvania, Philadelphia (S.J.); and the Center for Human Experimental Therapeutics, University of Rochester Medical Center, Rochester, NY (K.K.).

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http://dx.doi.org/10.1056/NEJMoa1312889DOI Listing
January 2014

Deliberation and the life cycle of informed consent.

Hastings Cent Rep 2014 Jan-Feb;44(1):33-5

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http://dx.doi.org/10.1002/hast.253DOI Listing
May 2014

Guidelines for return of research results from pediatric genomic studies: deliberations of the Boston Children's Hospital Gene Partnership Informed Cohort Oversight Board.

Genet Med 2014 Jul 9;16(7):547-52. Epub 2014 Jan 9.

1] Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA [2] Children's Hospital Informatics Program, Boston Children's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/gim.2013.190DOI Listing
July 2014

Evidence, errors, and ethics.

Perspect Biol Med 2014 ;57(3):299-307

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http://dx.doi.org/10.1353/pbm.2014.0024DOI Listing
November 2015

The National Cancer Institute-American Society of Clinical Oncology Cancer Trial Accrual Symposium: summary and recommendations.

J Oncol Pract 2013 Nov 15;9(6):267-76. Epub 2013 Oct 15.

National Cancer Institute; Education Network to Advance Cancer Clinical Trials, Bethesda; The EMMES Corporation, Rockville, MD; Delaware Cancer Consortium, Dover; Helen F. Graham Cancer Center, Newark, DE; American Society of Clinical Oncology, Alexandria, VA; Coalition of Cancer Cooperative Groups; University of Pennsylvania Perelman School of Medicine, Philadelphia, PA; Cancer Information & Support Network, Auburn, CA; Oregon Health & Science University, Portland, OR; Pancreatic Cancer Action Network; Brooklyn Hospital Center, New York, NY; Massachusetts General Hospital, Boston, MA; Duke Clinical Research Institute, Durham; Levine Cancer Institute, Carolinas HealthCare System, Charlotte, NC; Michiana Hematology Oncology and Northern Indiana Cancer Research Consortium, South Bend, IN; Barbara Ann Karmanos Cancer Institute, Detroit, MI; University of Arizona Cancer Center, Tucson, AZ; University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland; The Ohio State University, Columbus, OH; University of Alabama at Birmingham, Birmingham, AL; Indiana University Simon Cancer Center, Indianapolis, IN; Heartland Cancer Research CCOP, St. Louis, MO; Meharry Medical College; and Vanderbilt-Ingram Cancer Center, Nashville, TN.

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http://dx.doi.org/10.1200/JOP.2013.001119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825288PMC
November 2013

Prevalence of hematopoietic cell transplant survivors in the United States.

Biol Blood Marrow Transplant 2013 Oct 30;19(10):1498-501. Epub 2013 Jul 30.

National Marrow Donor Program, Minneapolis, Minnesota; Center for International Blood and Marrow Transplant Research, Minneapolis, Minnesota. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2013.07.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779514PMC
October 2013

A phase 3 trial of semagacestat for treatment of Alzheimer's disease.

N Engl J Med 2013 Jul;369(4):341-50

Alzheimer's Disease and Memory Disorders Center, Department of Neurology, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1056/NEJMoa1210951DOI Listing
July 2013