Steven Goossens

Steven Goossens

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Steven Goossens

Steven Goossens

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The physiology of movement.

Mov Ecol 2020 4;8. Epub 2020 Feb 4.

1Department of Biology, Ghent University, K.L. Ledeganckstraat 35, 9000 Ghent, Belgium.

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http://dx.doi.org/10.1186/s40462-020-0192-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001223PMC
February 2020

ZEB2 in T-cells and T-ALL.

Adv Biol Regul 2019 12 27;74:100639. Epub 2019 Jul 27.

Department of Biomolecular Medicine, Ghent University, Ghent, Belgium; Cancer Research Institute Ghent (CRIG), Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.jbior.2019.100639DOI Listing
December 2019

Targeting steroid resistance in T-cell acute lymphoblastic leukemia.

Blood Rev 2019 11 19;38:100591. Epub 2019 Jul 19.

Department of Biomolecular Medicine, Ghent University, Ghent, Belgium; Cancer Research Institute Ghent (CRIG), Ghent, Belgium. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0268960X193003
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http://dx.doi.org/10.1016/j.blre.2019.100591DOI Listing
November 2019

ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms.

Haematologica 2019 Aug 24;104(8):1608-1616. Epub 2019 Jan 24.

Mammalian Functional Genetics Group, Australian Centre for Blood Diseases, Monash University, Melbourne, VIC, Australia.

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http://dx.doi.org/10.3324/haematol.2018.207837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669144PMC
August 2019

ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition.

Epigenetics Chromatin 2018 11 16;11(1):70. Epub 2018 Nov 16.

Molecular and Cellular Oncology Laboratory, Department of Biomedical Molecular Biology, Ghent University, Technologiepark 927, 9052, Zwijnaarde, Ghent, Belgium.

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https://epigeneticsandchromatin.biomedcentral.com/articles/1
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http://dx.doi.org/10.1186/s13072-018-0239-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240308PMC
November 2018

ZEB Proteins in Leukemia: Friends, Foes, or Friendly Foes?

Hemasphere 2018 Jun 11;2(3):e43. Epub 2018 May 11.

Department for Biomedical Molecular Biology, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1097/HS9.0000000000000043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745990PMC
June 2018

A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8.

Acta Neuropathol 2018 01 5;135(1):131-148. Epub 2017 Aug 5.

Peripheral Neuropathy Research Group, Department of Biomedical Sciences and Institute Born Bunge, University of Antwerp, Universiteitsplein 1, 2610, Antwerpen, Belgium.

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http://dx.doi.org/10.1007/s00401-017-1756-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756276PMC
January 2018

LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis.

Blood 2018 01 30;131(1):95-107. Epub 2017 Oct 30.

Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, Katholieke Universiteit (KU) Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1182/blood-2017-05-786962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755044PMC
January 2018

EMT transcription factors in cancer development re-evaluated: Beyond EMT and MET.

Biochim Biophys Acta Rev Cancer 2017 Dec 29;1868(2):584-591. Epub 2017 Jun 29.

Molecular Cellular Oncology Lab, Department for Biomedical Molecular Biology, Ghent University, Ghent, Belgium; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2017.06.006DOI Listing
December 2017

Epithelial-to-Mesenchymal Transition: Epigenetic Reprogramming Driving Cellular Plasticity.

Trends Genet 2017 12 14;33(12):943-959. Epub 2017 Sep 14.

Molecular and Cellular Oncology Laboratory, Department for Biomedical Molecular Biology, Ghent University, Ghent, Belgium; Cancer Research Institute Ghent (CRIG), Ghent, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.tig.2017.08.004DOI Listing
December 2017

Structure-function Studies in Mouse Embryonic Stem Cells Using Recombinase-mediated Cassette Exchange.

J Vis Exp 2017 04 27(122). Epub 2017 Apr 27.

Department of Biomedical Molecular Biology, Ghent University; Inflammation Research Center, VIB; Center for Medical Genetics, Ghent University Hospital; Cancer Research Institute Ghent (CRIG);

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http://dx.doi.org/10.3791/55575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565114PMC
April 2017

Overcoming Steroid Resistance in T Cell Acute Lymphoblastic Leukemia.

PLoS Med 2016 Dec 20;13(12):e1002208. Epub 2016 Dec 20.

Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1371/journal.pmed.1002208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172529PMC
December 2016

Characterization of New Transgenic Mouse Models for Two Charcot-Marie-Tooth-Causing HspB1 Mutations using the Rosa26 Locus.

J Neuromuscul Dis 2016 05;3(2):183-200

Peripheral Neuropathy Group, VIB Department of Molecular Genetics and Institute Born Bunge, University of Antwerp, Antwerpen, Belgium.

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http://dx.doi.org/10.3233/JND-150144DOI Listing
May 2016

Loss of autocrine endothelial-derived VEGF significantly reduces hemangiosarcoma development in conditional p53-deficient mice.

Cell Cycle 2014 11;13(9):1501-7. Epub 2014 Mar 11.

Vascular Cell Biology Unit; Department for Molecular Biomedical Research; VIB-Ghent University; Ghent, Belgium; Department of Biomedical Molecular Biology; Ghent University; Ghent, Belgium; Australian Centre for Blood Diseases; Monash University; Melbourne, Victoria, Australia.

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http://dx.doi.org/10.4161/cc.28474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050148PMC
April 2016

Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection.

J Exp Med 2015 Nov 26;212(12):2015-25. Epub 2015 Oct 26.

Université de Lyon, 69007 Lyon, France Institut National de la Santé et de la Recherche Médicale, U1111, 69342 Lyon, France Ecole Normale Supérieure de Lyon, 69007 Lyon, France Centre International de Recherche en Infectiologie, 69007 Lyon, France Centre National de la Recherche Scientifique, UMR5308, 69342 Lyon, France

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http://dx.doi.org/10.1084/jem.20150809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647267PMC
November 2015

Alpha-catenins control cardiomyocyte proliferation by regulating Yap activity.

Circ Res 2015 Jan 10;116(1):70-9. Epub 2014 Oct 10.

From the Department of Medicine, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, PA (J.L., E.G., A.V., R.Y., L.G., G.L.R.); Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium (S.G., F.v.R.); Inflammation Research Center, Flanders Institute for Biotechnology (VIB), Ghent, Belgium (S.G., F.v.R.); and INSERM UMR-1060, Laboratoire CarMeN, Université Lyon 1, Faculté de médecine, Rockefeller et Charles Merieux Lyon-Sud, Lyon, France (L.G.). Current address for E.G.: Center for Translational Medicine, Temple University School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.304472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282606PMC
January 2015

ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling.

Nat Commun 2015 Jan 7;6:5794. Epub 2015 Jan 7.

1] Vascular Cell Biology Unit, VIB Inflammation Research Center, Ghent University, Ghent B-9052, Belgium [2] Department for Biomedical Molecular Biology, Ghent University, Ghent B-9052, Belgium [3] Mammalian Functional Genetics Laboratory, Division of Blood Cancers, Australian Centre for Blood Diseases, Department of Clinical Haematology, Monash University and Alfred Health Alfred Centre, 99 Commercial Road, Melbourne, Victoria 3004, Australia.

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http://dx.doi.org/10.1038/ncomms6794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354161PMC
January 2015

Controlling pre-leukemic thymocyte self-renewal.

PLoS Genet 2014 Dec 18;10(12):e1004881. Epub 2014 Dec 18.

Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1371/journal.pgen.1004881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270492PMC
December 2014

ZEB2-transgene expression in the epidermis compromises the integrity of the epidermal barrier through the repression of different tight junction proteins.

Cell Mol Life Sci 2014 Sep 27;71(18):3599-609. Epub 2014 Feb 27.

Unit of Molecular and Cellular Oncology, Inflammation Research Center, VIB, Technologiepark 927, 9052, Ghent (Zwijnaarde), Belgium.

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http://dx.doi.org/10.1007/s00018-014-1589-0DOI Listing
September 2014

The ROSA26-iPSC mouse: a conditional, inducible, and exchangeable resource for studying cellular (De)differentiation.

Cell Rep 2013 Feb 7;3(2):335-41. Epub 2013 Feb 7.

Vascular Cell Biology Unit, VIB Department for Molecular Biomedical Research, Ghent University, Technologiepark 927, 9052 Zwijnaarde Ghent, Belgium.

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https://linkinghub.elsevier.com/retrieve/pii/S22111247130002
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http://dx.doi.org/10.1016/j.celrep.2013.01.016DOI Listing
February 2013

Design of Ru-zeolites for hydrogen-free production of conjugated linoleic acids.

ChemSusChem 2011 Jun 19;4(6):757-67. Epub 2011 Apr 19.

Department M2S, K.U. Leuven, Kasteelpark Arenberg 23, 3001 Heverlee, Belgium.

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http://dx.doi.org/10.1002/cssc.201100015DOI Listing
June 2011

Catalytic production of conjugated fatty acids and oils.

ChemSusChem 2011 Jun 1;4(6):684-702. Epub 2011 Jun 1.

Department M2S, K.U. Leuven, Kasteelpark Arenberg 23, 3001 Heverlee, Belgium.

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http://dx.doi.org/10.1002/cssc.201100086DOI Listing
June 2011

Plakophilin-3-deficient mice develop hair coat abnormalities and are prone to cutaneous inflammation.

J Invest Dermatol 2008 Jun 13;128(6):1375-85. Epub 2007 Dec 13.

Department for Molecular Biomedical Research, VIB, Ghent, Belgium.

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http://dx.doi.org/10.1038/sj.jid.5701189DOI Listing
June 2008

Alpha-T-catenin (CTNNA3) displays tumour specific monoallelic expression in urothelial carcinoma of the bladder.

Genes Chromosomes Cancer 2007 Jun;46(6):587-93

School of Medicine and Medical Science (SMMS), UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland.

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http://dx.doi.org/10.1002/gcc.20443DOI Listing
June 2007

Truncated isoform of mouse alphaT-catenin is testis-restricted in expression and function.

FASEB J 2007 Mar 21;21(3):647-55. Epub 2006 Dec 21.

Department for Molecular Biomedical Research, VIB-Ghent University, Technologiepark 927, B-9052 Ghent, Belgium.

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http://dx.doi.org/10.1096/fj.06-6066comDOI Listing
March 2007

Cadherin-mediated cell-cell adhesion in the testis.

Front Biosci 2005 Jan 1;10:398-419. Epub 2005 Jan 1.

Department for Molecular Biomedical Research, Flanders Interuniversity Institute for Biotechnology (VIB)-Ghent University, Technologiepark 927, B-9052 Ghent, Zwijnaarde, Belgium.

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http://dx.doi.org/10.2741/1537DOI Listing
January 2005

GATA-4 and MEF2C transcription factors control the tissue-specific expression of the alphaT-catenin gene CTNNA3.

Nucleic Acids Res 2004 9;32(14):4155-65. Epub 2004 Aug 9.

Unit of Molecular and Cellular Oncology, Department for Molecular Biomedical Research, VIB-Ghent University, B-9052 Ghent-Zwijnaarde, Belgium.

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http://dx.doi.org/10.1093/nar/gkh727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC514362PMC
August 2004

Assessment of the CTNNA3 gene encoding human alpha T-catenin regarding its involvement in dilated cardiomyopathy.

Hum Genet 2003 Mar 5;112(3):227-36. Epub 2002 Dec 5.

Department of Molecular Biomedical Research, Flanders Interuniversity Institute for Biotechnology, Ghent University, Belgium.

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http://dx.doi.org/10.1007/s00439-002-0857-5DOI Listing
March 2003