Publications by authors named "Steven G Kernie"

61Publications

Rapid exome sequencing in PICU patients with new-onset metabolic or neurological disorders.

Pediatr Res 2020 11 27;88(5):761-768. Epub 2020 Mar 27.

Division of Pediatric Critical Care Medicine, Columbia University, New York, NY, USA.

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November 2020

Apolipoprotein E regulates the maturation of injury-induced adult-born hippocampal neurons following traumatic brain injury.

PLoS One 2020 2;15(3):e0229240. Epub 2020 Mar 2.

Department of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, United States of America.

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June 2020

Child Abuse Taking Its Toll on the Emotional Well-Being of Pediatricians.

Clin Pediatr (Phila) 2020 05 18;59(4-5):450-457. Epub 2020 Feb 18.

Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, USA.

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May 2020

Hyaluronidase reduced edema after experimental traumatic brain injury.

J Cereb Blood Flow Metab 2020 Oct 24;40(10):2026-2037. Epub 2019 Oct 24.

Department of Biomedical Engineering, Columbia University, New York, NY, USA.

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October 2020

ApoE Regulates the Development of Adult Newborn Hippocampal Neurons.

eNeuro 2018 Jul-Aug;5(4). Epub 2018 Aug 2.

Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY 10032.

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March 2019

Assessment of Recovery Following Pediatric Traumatic Brain Injury.

Pediatr Crit Care Med 2018 04;19(4):353-360

Department of Pediatrics, The University of Texas Southwestern Medical Center, Children's Medical Center Dallas, Dallas, TX.

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April 2018

Adult newborn neurons interfere with fear discrimination in a protocol-dependent manner.

Brain Behav 2017 09 2;7(9):e00796. Epub 2017 Aug 2.

Department of Pediatrics Columbia University College of Physicians and Surgeons New York NY USA.

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September 2017

Depletion of adult neurogenesis exacerbates cognitive deficits in Alzheimer's disease by compromising hippocampal inhibition.

Mol Neurodegener 2017 09 8;12(1):64. Epub 2017 Sep 8.

Department of Anatomy and Cell Biology, College of Medicine, The University of Illinois at Chicago, 909 S Wolcott Ave, Chicago, IL, 60612, USA.

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September 2017

Intracerebroventricular administration of chondroitinase ABC reduces acute edema after traumatic brain injury in mice.

BMC Res Notes 2016 Mar 12;9:160. Epub 2016 Mar 12.

Department of Biomedical Engineering, Columbia University, 351 Engineering Terrace, Mail Code 8904, 1210 Amsterdam Avenue, New York, NY, 10027, USA.

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March 2016

Assessment of Traumatic Brain Injury by Increased 64Cu Uptake on 64CuCl2 PET/CT.

J Nucl Med 2015 Aug 25;56(8):1252-7. Epub 2015 Jun 25.

Center for Neurosciences and Regenerative Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland.

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August 2015

Perinatal chronic hypoxia induces cortical inflammation, hypomyelination, and peripheral myelin-specific T cell autoreactivity.

J Leukoc Biol 2016 Jan 2;99(1):21-9. Epub 2015 Jun 2.

Departments of *Neurology and Neurotherapeutics and Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Departments of Pediatrics and Pathology and Cell Biology, Columbia University Medical Center, New York, New York, USA; and Department of Accounting, School of Business, University of Texas at Arlington, Arlington, Texas, USA.

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January 2016

Apolipoprotein E Regulates Injury-Induced Activation of Hippocampal Neural Stem and Progenitor Cells.

J Neurotrauma 2016 Feb 11;33(4):362-74. Epub 2015 Jun 11.

1 Departments of Pediatrics and Pathology and Cell Biology, Columbia University College of Physicians and Surgeons , New York, New York.

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February 2016

Predicting Outcome after Pediatric Traumatic Brain Injury by Early Magnetic Resonance Imaging Lesion Location and Volume.

J Neurotrauma 2016 Jan 19;33(1):35-48. Epub 2015 Jun 19.

5 Department of Pediatrics, University of Texas Southwestern Medical Center , Dallas, Texas.

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January 2016

Aberrant hippocampal neurogenesis contributes to epilepsy and associated cognitive decline.

Nat Commun 2015 Mar 26;6:6606. Epub 2015 Mar 26.

Department of Molecular Biology and Hamon Center for Regenerative Science and Medicine, UT Southwestern Medical Center, Dallas, Texas 75390, USA.

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March 2015

Cell-based therapy for pediatric traumatic brain injury: not (yet) an update to the traumatic brain injury guidelines.

Authors:
Steven G Kernie

Pediatr Crit Care Med 2015 Mar;16(3):294-5

Departments of Pediatrics and Pathology & Cell Biology, Columbia University College of Physicians and Surgeons; and, Division of Pediatric Critical Care Medicine, New York Presbyterian Morgan Stanley Children's Hospital, New York, NY.

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March 2015

Donepezil rescues spatial learning and memory deficits following traumatic brain injury independent of its effects on neurogenesis.

PLoS One 2015 25;10(2):e0118793. Epub 2015 Feb 25.

Departments of Pediatrics and Pathology & Cell Biology, Columbia University College of Physicians and Surgeons, 3959 Broadway, CHN 10-24, New York, NY 10032, United States of America.

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January 2016

Injury-Induced Neurogenesis: Mechanisms and Relevance.

Neuroscientist 2016 Feb 17;22(1):61-71. Epub 2014 Dec 17.

Departments of Pediatrics and Pathology & Cell Biology, Columbia University College of Physicians and Surgeons, New York, NY, USA

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February 2016

Endogenous neural stem/progenitor cells stabilize the cortical microenvironment after traumatic brain injury.

J Neurotrauma 2015 Jun 27;32(11):753-64. Epub 2015 Feb 27.

1The Miami Project to Cure Paralysis and Department of Neurological Surgery, University of Miami, Miami, Florida.

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June 2015

Cerebrospinal fluid levels of extracellular heat shock protein 72: A potential biomarker for bacterial meningitis in children.

J Pediatr Intensive Care 2014 Mar;3(1):23-28

Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

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March 2014

Conditional ablation of neuroprogenitor cells in adult mice impedes recovery of poststroke cognitive function and reduces synaptic connectivity in the perforant pathway.

J Neurosci 2013 Oct;33(44):17314-25

Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94121, San Francisco VA Medical Center, San Francisco, California 94121, Department of Neurological Surgery, Second Affiliated Hospital of Zhejiang University Medical College, Hangzhou 310009, China, Department of Neurological Surgery, Xinhua Hospital, Shanghai Jiaotong University, Shanghai 201101, China, Department of Neurological Surgery, Tohoku University Graduate School of Medicine, Aoba-ku, Sendai 980-8574, Japan, Departments of Bioengineering and Ophthalmology, University of Washington, Seattle, Washington 98195, and Departments of Pediatrics, Pathology and Cell Biology, Columbia University, New York, New York 10032.

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October 2013

Advances in pediatric neurocritical care.

Pediatr Clin North Am 2013 Jun 7;60(3):709-24. Epub 2013 Mar 7.

Pediatric Critical Care Medicine, Department of Pediatrics, Morgan Stanley Children's Hospital, Columbia University Medical Center, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.

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June 2013

Pharmacological inhibition of the mTOR pathway impairs hippocampal development in mice.

Neurosci Lett 2013 Apr 6;541:9-14. Epub 2013 Feb 6.

Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, United States.

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April 2013

A restricted cell population propagates glioblastoma growth after chemotherapy.

Nature 2012 Aug;488(7412):522-6

Department of Developmental Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9133, USA.

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August 2012

Dual-mode modulation of Smad signaling by Smad-interacting protein Sip1 is required for myelination in the central nervous system.

Neuron 2012 Feb;73(4):713-28

Department of Developmental Biology and Kent Waldrep Foundation Center for Basic Neuroscience Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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February 2012

ApoE is required for maintenance of the dentate gyrus neural progenitor pool.

Development 2011 Oct 31;138(20):4351-62. Epub 2011 Aug 31.

Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.

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October 2011

miR-132 mediates the integration of newborn neurons into the adult dentate gyrus.

PLoS One 2011 17;6(5):e19077. Epub 2011 May 17.

The Vollum Institute, Oregon Health and Science University, Portland, Oregon, United States of America.

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September 2011

Protecting the future: neuroprotective strategies in the pediatric intensive care unit.

Curr Opin Pediatr 2011 Jun;23(3):275-80

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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June 2011

Temporally specified genetic ablation of neurogenesis impairs cognitive recovery after traumatic brain injury.

J Neurosci 2011 Mar;31(13):4906-16

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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March 2011

Age-related changes in the oligodendrocyte progenitor pool influence brain remodeling after injury.

Dev Neurosci 2010 14;32(5-6):499-509. Epub 2010 Dec 14.

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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May 2011

Developmental profiling of postnatal dentate gyrus progenitors provides evidence for dynamic cell-autonomous regulation.

Hippocampus 2011 Jan;21(1):33-47

Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA.

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January 2011

Forebrain neurogenesis after focal Ischemic and traumatic brain injury.

Neurobiol Dis 2010 Feb 10;37(2):267-74. Epub 2009 Nov 10.

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390-9133, USA.

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February 2010

Traumatic brain injury-induced hippocampal neurogenesis requires activation of early nestin-expressing progenitors.

J Neurosci 2008 Nov;28(48):12901-12

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9133, USA.

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November 2008

The basic helix-loop-helix transcription factor olig2 is critical for reactive astrocyte proliferation after cortical injury.

J Neurosci 2008 Oct;28(43):10983-9

Department of Developmental Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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October 2008

TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment.

Neuron 2008 Aug;59(3):399-412

Department of Developmental Biology, Kent Waldrep Center for Basic Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, TX 75390-9133, USA.

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August 2008

Hypoxic-ischemic brain injury activates early hippocampal stem/progenitor cells to replace vulnerable neuroblasts.

Hippocampus 2008 ;18(8):793-806

Department of Pediatrics, The University of Texas Southwestern Medical Center, Dallas, Texas 75390-9063, USA.

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November 2008

Brief exposure to hyperoxia depletes the glial progenitor pool and impairs functional recovery after hypoxic-ischemic brain injury.

J Cereb Blood Flow Metab 2008 Jul 12;28(7):1294-306. Epub 2008 Mar 12.

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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July 2008

EphB receptors regulate stem/progenitor cell proliferation, migration, and polarity during hippocampal neurogenesis.

J Neurosci 2007 Dec;27(49):13481-90

Department of Developmental Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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December 2007

Injury-induced neurogenesis in Bax-deficient mice: evidence for regulation by voltage-gated potassium channels.

Eur J Neurosci 2007 Jun;25(12):3499-512

Department of Pediatrics, The University of Texas Southwestern Medical Center, Dallas, TX 75390-9133, USA.

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June 2007

A crucial role for Olig2 in white matter astrocyte development.

Development 2007 May 11;134(10):1887-99. Epub 2007 Apr 11.

Department of Developmental Biology and Kent Waldrep Foundation Center for Basic Neuroscience Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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May 2007

Activation of neural stem and progenitor cells after brain injury.

Prog Brain Res 2006 ;157:187-197

Department of Pediatrics and Center for Developmental Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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January 2007

A critical role for dorsal progenitors in cortical myelination.

J Neurosci 2006 Jan;26(4):1275-80

Center for Developmental Biology, Kent Waldrep Foundation Center for Basic Neuroscience Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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January 2006

Differential expression of the four untranslated BDNF exons in the adult mouse brain.

J Neurosci Res 2006 Feb;83(2):211-21

Center for Developmental Biology and Kent Waldrep Foundation Center for Basic Neuroscience Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9133, USA.

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February 2006

Temporally regulated expression of Cre recombinase in neural stem cells.

Genesis 2005 Apr;41(4):147-53

Department of Pediatrics, U.T. Southwestern Medical Center, Dallas, Texas 75390-9063, USA.

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April 2005

Subventricular zone neural stem cells remodel the brain following traumatic injury in adult mice.

J Neurotrauma 2004 Mar;21(3):283-92

Center for Developmental Biology and Kent Waldrep Foundation Center for Basic Research on Nerve Growth and Regeneration, U.T. Southwestern Medical Center, Dallas, Texas 75390-9133, USA.

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March 2004