Steven D Targum

Steven D Targum

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Steven D Targum

Steven D Targum

Publications by authors named "Steven D Targum"

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Audio-digital recordings for surveillance in clinical trials of major depressive disorder.

Contemp Clin Trials Commun 2019 Jun 8;14:100317. Epub 2019 Jan 8.

Bracket Global, 2 Oliver Street, Suite 1003, Boston, MA, 02109, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S24518654183016
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http://dx.doi.org/10.1016/j.conctc.2019.100317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348193PMC
June 2019

The Effect of Early Life Stress on Adult Psychiatric Disorders.

Innov Clin Neurosci 2019 Jan;16(1-2):35-37

Dr. Targum is Scientific Director with CRF-Bracket in Boston, Massachusetts.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450674PMC
January 2019

Ratings surveillance and reliability in a study of major depressive disorder with subthreshold hypomania (mixed features).

Int J Methods Psychiatr Res 2018 12 26;27(4):e1729. Epub 2018 Jun 26.

Sunovion Pharmaceuticals, Fort Lee, New Jersey, USA.

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http://dx.doi.org/10.1002/mpr.1729DOI Listing
December 2018

An augmentation study of MSI-195 (S-adenosylmethionine) in Major Depressive Disorder.

J Psychiatr Res 2018 12 18;107:86-96. Epub 2018 Oct 18.

MSI Methylation Sciences Inc, Burnaby, BC, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S00223956183081
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http://dx.doi.org/10.1016/j.jpsychires.2018.10.010DOI Listing
December 2018

Audio Recording for Independent Confirmation of Clinical Assessments in Generalized Anxiety Disorder.

Innov Clin Neurosci 2018 Apr;15(3-4):37-42

Drs. Targum and Murphy are with Bracket Global LLC in Boston, Massachusetts.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919431PMC
April 2018

Cognitive Impairment Associated with Cancer: A Brief Review.

Innov Clin Neurosci 2018 Feb;15(1-2):36-44

Drs. Pendergrass and Targum are with Bracket Global and Clintara LLC, A Bracket Company, in Boston, Massachusetts.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819720PMC
February 2018

Early symptomatic improvement affects treatment outcome in a study of major depressive disorder.

Authors:
Steven D Targum

J Psychiatr Res 2017 12 8;95:276-281. Epub 2017 Sep 8.

Bracket Global LLC, 2 Oliver Street, Suite 1003, Boston, MA 02109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2017.09.009DOI Listing
December 2017

Early symptomatic improvement affects treatment outcome in a study of major depressive disorder.

Authors:
Steven D Targum

J Psychiatr Res 2017 12 8;95:276-281. Epub 2017 Sep 8.

Bracket Global LLC, 2 Oliver Street, Suite 1003, Boston, MA 02109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2017.09.009DOI Listing
December 2017

Effect of patient age on treatment response in a study of the acute exacerbation of psychosis in schizophrenia.

Schizophr Res 2017 01 1;179:64-69. Epub 2016 Oct 1.

Alkermes, Inc., 852 Winter Street, Waltham, MA 02451, USA.

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http://dx.doi.org/10.1016/j.schres.2016.09.034DOI Listing
January 2017

Major depressive disorder with subthreshold hypomania (mixed features): Clinical characteristics of patients entered in a multiregional, placebo-controlled study.

Prog Neuropsychopharmacol Biol Psychiatry 2016 Jul 22;68:9-14. Epub 2016 Feb 22.

Sunovion Pharmaceuticals Inc., Fort Lee, NJ and Marlborough, MA, United States.

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http://dx.doi.org/10.1016/j.pnpbp.2016.02.007DOI Listing
July 2016

Changes in cognitive symptoms after a buspirone-melatonin combination treatment for Major Depressive Disorder.

J Psychiatr Res 2015 Sep 9;68:392-6. Epub 2015 May 9.

Massachusetts General Hospital, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2015.04.024DOI Listing
September 2015

Impact of BPRS interview length on ratings reliability in a schizophrenia trial.

Eur Neuropsychopharmacol 2015 Mar 13;25(3):312-8. Epub 2014 Dec 13.

Pfizer Inc., Cambridge, MA, United States.

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http://dx.doi.org/10.1016/j.euroneuro.2014.11.023DOI Listing
March 2015

Our current understanding of adult ADHD.

Innov Clin Neurosci 2014 Nov-Dec;11(11-12):30-5

Steven D. Targum, MD, is the scientific director at Clintara LLC, the chief medical officer at Methylation Sciences Inc., BrainCells Inc., and Functional Neuromodulation Inc., the chief medical advisor at Prana Biotechnology Ltd., and a consultant in psychiatry at the Massachusetts General Hospital, Boston, Massachusetts. Dr. Adler is Professor of Psychiatry and Child and Adolescent Psychiatry at New York University School of Medicine and Director of the adult ADHD program at New York University Medical Center in New York City.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301030PMC
January 2015

Audio-digital recordings used for independent confirmation of site-based MADRS interview scores.

Eur Neuropsychopharmacol 2014 Nov 6;24(11):1760-6. Epub 2014 Sep 6.

PPD Inc. (formerly CeNeRx Pharmaceuticals), Wilmington, NC, USA.

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http://dx.doi.org/10.1016/j.euroneuro.2014.08.016DOI Listing
November 2014

Impact of BPRS interview length on ratings reliability in a schizophrenia trial.

Eur Neuropsychopharmacol 2015 Mar 13;25(3):312-8. Epub 2014 Dec 13.

Pfizer Inc., Cambridge, MA, United States.

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http://dx.doi.org/10.1016/j.euroneuro.2014.11.023DOI Listing
March 2015

Use of band-pass filter analysis to evaluate outcomes in an antidepressant trial for treatment resistant patients.

Eur Neuropsychopharmacol 2014 Aug 17;24(8):1188-95. Epub 2014 Jun 17.

Massachusetts General Hospital, Boston, MA, United States.

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http://dx.doi.org/10.1016/j.euroneuro.2014.06.003DOI Listing
August 2014

Identification and treatment of antidepressant tachyphylaxis.

Authors:
Steven D Targum

Innov Clin Neurosci 2014 Mar;11(3-4):24-8

Dr. Targum is with Clintara, LLC, Boston, Massachusetts.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008298PMC
March 2014

A cross-cultural comparison study of depression assessments conducted in Japan.

Ann Gen Psychiatry 2013 Apr 3;12(1). Epub 2013 Apr 3.

Clintara LLC, 505 Tremont Street, #907, Boston, MA 02116, USA.

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http://dx.doi.org/10.1186/1744-859X-12-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620710PMC
April 2013

Psychiatry in the ukraine.

Innov Clin Neurosci 2013 Apr;10(4):41-6

Steven D. Targum, MD, is the scientific director at Clintara LLC, the chief medical officer at Methylation Sciences Inc., BrainCells Inc., and Functional Neuromodulation Inc., the chief medical advisor at Prana Biotechnology Ltd., and a consultant in psychiatry at the Massachusetts General Hospital, Boston, Massachusetts. Prof. Oleh Chaban is the director of the Clinic for Borderline Conditions at the Scientific Research Institute of Social and Forensic Psychiatry and Narcology in Kiev, the vice president of the Ukrainian Association of Psychotherapists and Psychoanalytics, and an academician of the Ukrainian Academy of Sciences of High School in the Ukraine. Dr. Serhiy Mykhnyak is a psychiatrist and researcher at the Lviv District Clinical Psychiatric Hospital in the Ukraine.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659038PMC
April 2013

Deep brain stimulation: a novel strategy for treating Alzheimer's disease.

Innov Clin Neurosci 2012 Nov;9(11-12):10-7

Constantine G. Lyketsos, MD, MHS, is Elizabeth Plank Althouse Professor, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University and Chair of Psychiatry at Johns Hopkins Bayview Medical Center; Steven D. Targum, MD, is Scientific Director at Clintara LLC, Chief Medical Officer at Methylation Sciences Inc., BrainCells Inc., and Functional Neuromodulation Inc., Chief Medical Advisor at Prana Biotechnology Ltd., and a consultant in psychiatry at the Massachusetts General Hospital; Jo Cara Pendergrass, PhD is Vice President of Clinical Operations at Clintara LLC; Andres M. Lozano MD, PhD, FRCSC, FRSC, is Dan Family Professor and Chairman of Neurosurgery at the University of Toronto and RR Tasker Chair in Functional Neurosurgery (Toronto Western Hospital), and Canada Research Chair in Neuroscience.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552463PMC
November 2012

A global measure to assess switching antipsychotic medications in the treatment of schizophrenia.

Hum Psychopharmacol 2012 Sep 24;27(5):455-63. Epub 2012 Jul 24.

Clintara LLC, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/hup.2247DOI Listing
September 2012

Educating the public through the courtroom: efforts of a forensic psychologist.

Innov Clin Neurosci 2012 Jul;9(7-8):48-50

Massachusetts General Hospital, Psychiatry, Boston, Masschussetts, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442751PMC
July 2012

Development of a clinical global impression scale for fatigue.

J Psychiatr Res 2012 Mar 10;46(3):370-4. Epub 2012 Jan 10.

Clintara LLC, 505 Tremont Street #907, Boston, MA 02116, USA.

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http://dx.doi.org/10.1016/j.jpsychires.2011.12.001DOI Listing
March 2012

A global measure to assess switching antipsychotic medications in the treatment of schizophrenia.

Hum Psychopharmacol 2012 Sep 24;27(5):455-63. Epub 2012 Jul 24.

Clintara LLC, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/hup.2247DOI Listing
September 2012

Fatigue as a residual symptom of depression.

Innov Clin Neurosci 2011 Oct;8(10):40-3

Department of Psychiatry, Massachusetts General Hospital, Massachusetts, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225130PMC
October 2011

The complexity of "mixed" depression: a common clinical presentation.

Innov Clin Neurosci 2011 Jun;8(6):38-42

Department of Psychiatry, Massachusetts General Hospital, Massachusetts, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140897PMC
June 2011

The Distinction between Clinical and Research Interviews in Psychiatry.

Authors:
Steven D Targum

Innov Clin Neurosci 2011 Mar;8(3):40-4

Dr. Targum is a consultant for the Department of Psychiatry at the Massachusetts General Hospital. Dr. Targum is on the editorial board of Innovations in Clinical Neuroscience .

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074196PMC
March 2011

Neurobehavioral problems associated with phenylketonuria.

Psychiatry (Edgmont) 2010 Dec;7(12):29-32

Dr. Targum is a consultant for the Department of Psychiatry at the Massachusetts General Hospital. Dr. Targum is on the editorial board of Psychiatry 2010.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028461PMC
December 2010

The status of nutraceuticals for the treatment of depression.

Psychiatry (Edgmont) 2009 Sep;6(9):46-8

Dr. Targum is an executive-in-residence at Oxford BioScience Partners and on the faculty of the Department of Psychiatry at the Massachusetts General Hospital. Dr. Targum is chief medical officer at BrainCells Inc. and chief medical advisor to Prana Biotechnology Ltd. Dr. Targum is on the editorial board of Psychiatry 2009.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766289PMC
September 2009

The Clinical Global Impressions scale: errors in understanding and use.

Compr Psychiatry 2009 May-Jun;50(3):257-62. Epub 2008 Oct 16.

Department of Psychiatry, Penn State College of Medicine, Hershey, PA, USA.

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http://dx.doi.org/10.1016/j.comppsych.2008.08.005DOI Listing
August 2009

Clinical applications of neuroimaging for treating depressive disorders.

Psychiatry (Edgmont) 2009 Jun;6(6):49-51

Dr. Targum is an executive-in-residence at Oxford BioScience Partners and on the faculty of the Department of Psychiatry at the Massachusetts General Hospital. Dr. Targum is chief medical officer at BrainCells Inc., and chief medical advisor to Prana Biotechnology Ltd. Dr. Targum is on the editorial board of Psychiatry 2009 .

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720847PMC
June 2009

Cognition and schizophrenia: is there a role for cognitive assessments in diagnosis and treatment?

Psychiatry (Edgmont) 2008 Dec;5(12):55-9

Dr. Targum is an executive-in-residence at Oxford BioScience Partners and on the faculty of the Department of Psychiatry at the Massachusetts General Hospital. Dr. Targum is chief medical officer at BrainCells Inc., and chief medical advisor to Prana Biotechnology Ltd. Dr. Targum is on the editorial board of Psychiatry 2008.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729617PMC
December 2008

Targeted scoring criteria reduce variance in global impressions.

Hum Psychopharmacol 2008 Oct;23(7):629-33

Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/hup.966DOI Listing
October 2008

Redefining affective disorders: relevance for drug development.

CNS Neurosci Ther 2008 ;14(1):2-9

Department of Psychiatry, Clinical Trials Network and Institute, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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http://doi.wiley.com/10.1111/j.1527-3458.2008.00038.x
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http://dx.doi.org/10.1111/j.1527-3458.2008.00038.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494001PMC
August 2008

The process of getting new drugs to market.

Psychiatry (Edgmont) 2008 Aug;5(8):57-60

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695743PMC
August 2008

Seasonal affective disorder.

Psychiatry (Edgmont) 2008 May;5(5):31-3

Dr. Targum is an executive-in-residence at Oxford BioScience Partners, on the faculty of the Department of Psychiatry at the Massachusetts General Hospital, chief medical officer at BrainCells Inc., chief medical advisor to Prana Biotechnology Ltd., and is on the editorial advisory board of Psychiatry 2008.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686645PMC
May 2008

Biomarkers for the identification and treatment of dementia.

Authors:
Steven D Targum

Psychiatry (Edgmont) 2008 Feb;5(2):51-6

Dr. Targum is an executive-in-residence at Oxford BioScience Partners and on the faculty of the Department of Psychiatry at the Massachusetts General Hospital. Dr. Targum is chief medical officer at BrainCells Inc., and chief medical advisor to Prana Biotechnology Ltd. Dr. Targum is on the editorial staff of Psychiatry 2008.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731690PMC
February 2008

Revisiting the Clinical Utility of Cytochrome p450 in Practice.

Psychiatry (Edgmont) 2007 Nov;4(11):28-30

Nierenberg is Director, Bipolar Trials Network, Medical Director, Bipolar Clinic and Research Program, Associate Director, Depression Clinical Reserach Program, and Professor of Psychiatry, Harvard Medical School, Boston, Massachusetts.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860515PMC
November 2007

The clinical global impressions scale: applying a research tool in clinical practice.

Psychiatry (Edgmont) 2007 Jul;4(7):28-37

Dr. Busner is Clinical Associate Professor of Psychiatry, Penn State College of Medicine, and Clinical Manager, United BioSource Corporation, Wayne, Pennsylvania.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880930PMC
July 2007

Hippocampal Neurogenesis: Can it be a Marker for New Antidepressants?

Psychiatry (Edgmont) 2007 May;4(5):18-20

Dr. Barlow is the Chief Scientific Officer at BrainCells Inc., San Deigo, California.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922342PMC
May 2007

Augmentation and combination strategies to treat the residual symptoms of major depressive disorder.

Psychiatry (Edgmont) 2007 Feb;4(2):16-8

Dr. Fava is Vice-Chair, Department of Psychiatry, Massachusetts General Hospital and Professor of Psychiatry, Harvard Medical School, Boston, Massachusetts.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922343PMC
February 2007

Neuroscience and clinical practice: applying pharmacogenomics in psychiatry.

Psychiatry (Edgmont) 2006 Nov;3(11):39-41

Dr. Targum is a consultant in psychiatry at Massachusetts General Hospital. Presently, he is also Medical Director at BrainCells Inc., Principal Scientific Advisor at UBC-TEG, and an Executive-in-residence at Oxford BioScience Partners in Boston, Massachusetts. Dr. Targum also serves on the Editorial Advisory Board of Psychiatry 2006 .

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945838PMC
November 2006

Strategies for maximizing clinical effectiveness in the treatment of schizophrenia.

J Psychiatr Pract 2006 Nov;12(6):348-63

Florida Department of Children and Families, Tallahassee, FL 32399, USA.

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November 2006

Culture and assessment of manic symptoms.

Br J Psychiatry 2006 Oct;189:379-80

School of Neurology, Neurobiology and Psychiatry, University of Newcastle upon Tyne, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, UK.

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http://dx.doi.org/10.1192/bjp.bp.105.013920DOI Listing
October 2006

Evaluating rater competency for CNS clinical trials.

Authors:
Steven D Targum

J Clin Psychopharmacol 2006 Jun;26(3):308-10

UBC-PharmaStar, Wayne, PA, USA.

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http://dx.doi.org/10.1097/01.jcp.0000219049.33008.b7DOI Listing
June 2006

Defining and measuring clinical effectiveness in the treatment of schizophrenia.

Psychiatr Serv 2005 Mar;56(3):273-82

Department of Psychiatry, University of Cincinnati Medical Center, Cincinnati, Ohio 45267-0559, USA.

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http://dx.doi.org/10.1176/appi.ps.56.3.273DOI Listing
March 2005

Psychosis in elderly patients: classification and pharmacotherapy.

J Geriatr Psychiatry Neurol 2003 Dec;16(4):199-206

Medical University of South Carolina, Institute of Psychiatry, Charleston 29406, USA.

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http://dx.doi.org/10.1177/0891988703258658DOI Listing
December 2003

A randomized, double-blind, placebo-controlled, fixed-dose, multicenter study of pregabalin in patients with generalized anxiety disorder.

J Clin Psychopharmacol 2003 Jun;23(3):240-9

Pfizer Global Research and Development, Ann Arbor Laboratories, 2800 Plymouth Road, Ann Arbor, MI 48105, USA.

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http://dx.doi.org/10.1097/01.jcp.0000084032.22282.ffDOI Listing
June 2003

Treating Psychotic Symptoms in Elderly Patients.

Authors:
Steven D. Targum

Prim Care Companion J Clin Psychiatry 2001 Aug;3(4):156-163

Clinical Studies, Philadelphia, Pa.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC181181PMC
http://dx.doi.org/10.4088/pcc.v03n0402DOI Listing
August 2001