Publications by authors named "Steven C Almo"

100Publications

Redesigning HVEM Interface for Selective Binding to LIGHT, BTLA, and CD160.

Structure 2020 Nov 13;28(11):1197-1205.e2. Epub 2020 Aug 13.

Department of Systems and Computational Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA; Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.str.2020.07.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642093PMC
November 2020

Narrow-Spectrum Antibiotic Targeting of the Radical SAM Enzyme MqnE in Menaquinone Biosynthesis.

Biochemistry 2020 Jul 5;59(27):2562-2575. Epub 2020 Jul 5.

Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.

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http://dx.doi.org/10.1021/acs.biochem.0c00070DOI Listing
July 2020

Viperin Reveals Its True Function.

Annu Rev Virol 2020 Sep 30;7(1):421-446. Epub 2020 Jun 30.

Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA; email:

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http://dx.doi.org/10.1146/annurev-virology-011720-095930DOI Listing
September 2020

Structure of a single-chain H2A/H2B dimer.

Acta Crystallogr F Struct Biol Commun 2020 May 28;76(Pt 5):194-198. Epub 2020 Apr 28.

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1107/S2053230X20004604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193513PMC
May 2020

A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5.

Biochemistry 2020 Oct 31;59(39):3696-3708. Epub 2020 Mar 31.

Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.

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http://dx.doi.org/10.1021/acs.biochem.0c00035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529705PMC
October 2020

An essential bifunctional enzyme in for itaconate dissimilation and leucine catabolism.

Proc Natl Acad Sci U S A 2019 08 18;116(32):15907-15913. Epub 2019 Jul 18.

Mycobacterial Metabolism and Antibiotic Research Laboratory, The Francis Crick Institute, London NW1 1AT, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1906606116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689899PMC
August 2019

The active site of the branched-chain amino acid biosynthesis enzyme dihydroxyacid dehydratase contains a 2Fe-2S cluster.

J Biol Chem 2019 08 16;294(35):13158-13170. Epub 2019 Jul 16.

Maurice Wilkins Center for Molecular Biodiscovery and School of Biological Sciences, University of Auckland, Auckland 1010, New Zealand

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http://dx.doi.org/10.1074/jbc.RA119.009498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721945PMC
August 2019

Structural Basis of CD160:HVEM Recognition.

Structure 2019 08 20;27(8):1286-1295.e4. Epub 2019 Jun 20.

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA; Department of Physiology and Biophysics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.str.2019.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477951PMC
August 2019

Computational Redesign of PD-1 Interface for PD-L1 Ligand Selectivity.

Structure 2019 05 28;27(5):829-836.e3. Epub 2019 Mar 28.

Department of Systems and Computational Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA; Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.str.2019.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745709PMC
May 2019

Genetically modified hematopoietic stem/progenitor cells that produce IL-10-secreting regulatory T cells.

Proc Natl Acad Sci U S A 2019 02 25;116(7):2634-2639. Epub 2019 Jan 25.

Department of Stem Cell & Regenerative Biology, Harvard University, Cambridge, MA 02138;

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http://dx.doi.org/10.1073/pnas.1811984116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377493PMC
February 2019

Substrate Profile of the Phosphotriesterase Homology Protein from Escherichia coli.

Biochemistry 2018 10 16;57(43):6219-6227. Epub 2018 Oct 16.

Department of Chemistry , Texas A&M University , College Station , Texas 77843 , United States.

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http://pubs.acs.org/doi/10.1021/acs.biochem.8b00935
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http://dx.doi.org/10.1021/acs.biochem.8b00935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643279PMC
October 2018

Novel Metabolic Pathways and Regulons for Hexuronate Utilization in Proteobacteria.

J Bacteriol 2019 01 20;201(2). Epub 2018 Dec 20.

A. A. Kharkevich Institute for Information Transmission Problems, Russian Academy of Sciences, Moscow, Russia

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http://jb.asm.org/lookup/doi/10.1128/JB.00431-18
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http://dx.doi.org/10.1128/JB.00431-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304669PMC
January 2019

Identification of a novel tRNA wobble uridine modifying activity in the biosynthesis of 5-methoxyuridine.

Nucleic Acids Res 2018 09;46(17):9160-9169

Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Korea.

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http://dx.doi.org/10.1093/nar/gky592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158493PMC
September 2018

Development and Evaluation of an Optimal Human Single-Chain Variable Fragment-Derived BCMA-Targeted CAR T Cell Vector.

Mol Ther 2018 06 28;26(6):1447-1456. Epub 2018 Mar 28.

Cellular Therapeutics Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2018.03.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986730PMC
June 2018

X-ray and EPR Characterization of the Auxiliary Fe-S Clusters in the Radical SAM Enzyme PqqE.

Biochemistry 2018 02 6;57(8):1306-1315. Epub 2018 Feb 6.

Department of Biochemistry, Albert Einstein School of Medicine , Bronx, New York 10461, United States.

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http://dx.doi.org/10.1021/acs.biochem.7b01097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905707PMC
February 2018

Mechanism and Structure of γ-Resorcylate Decarboxylase.

Biochemistry 2018 06 19;57(22):3167-3175. Epub 2018 Jan 19.

Department of Chemistry , Texas A&M University , College Station , Texas 77842 , United States.

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http://dx.doi.org/10.1021/acs.biochem.7b01213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988983PMC
June 2018

Structures of the L27 Domain of Disc Large Homologue 1 Protein Illustrate a Self-Assembly Module.

Biochemistry 2018 02 7;57(8):1293-1305. Epub 2018 Feb 7.

Department of Biochemistry, Albert Einstein College of Medicine , Bronx, New York 10461, United States.

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http://dx.doi.org/10.1021/acs.biochem.7b01074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568269PMC
February 2018

Tumor-expressed immune checkpoint B7x promotes cancer progression and antigen-specific CD8 T cell exhaustion and suppressive innate immune cells.

Oncotarget 2017 Oct 20;8(47):82740-82753. Epub 2017 Sep 20.

Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.

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http://dx.doi.org/10.18632/oncotarget.21098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669925PMC
October 2017

General principles of binding between cell surface receptors and multi-specific ligands: A computational study.

PLoS Comput Biol 2017 Oct 10;13(10):e1005805. Epub 2017 Oct 10.

Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1005805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654264PMC
October 2017

Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides.

J Am Chem Soc 2017 08 21;139(34):11734-11744. Epub 2017 Aug 21.

Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.

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http://dx.doi.org/10.1021/jacs.7b01283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443407PMC
August 2017

Can the propensity of protein crystallization be increased by using systematic screening with metals?

Protein Sci 2017 Sep 29;26(9):1704-1713. Epub 2017 Jun 29.

Division of Biological Sciences, Poornaprajna Institute of Scientific Research, Bangalore, 560080, India.

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http://dx.doi.org/10.1002/pro.3214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563152PMC
September 2017

The hidden treasure in your data: phasing with unexpected weak anomalous scatterers from routine data sets.

Acta Crystallogr F Struct Biol Commun 2017 04 22;73(Pt 4):184-195. Epub 2017 Mar 22.

Division of Biological Sciences, Poornaprajna Institute of Scientific Research, #4, 16th Cross, Sadashivnagar, Bangalore 560 080, India.

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http://dx.doi.org/10.1107/S2053230X17002680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379167PMC
April 2017

Stilbene epoxidation and detoxification in a -nematode symbiosis.

J Biol Chem 2017 04 28;292(16):6680-6694. Epub 2017 Feb 28.

From the Department of Chemistry, Yale University, New Haven, Connecticut 06520,

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http://dx.doi.org/10.1074/jbc.M116.762542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399116PMC
April 2017

Structure-guided development of a high-affinity human Programmed Cell Death-1: Implications for tumor immunotherapy.

EBioMedicine 2017 Mar 6;17:30-44. Epub 2017 Feb 6.

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461, USA; Department of Physiology & Biophysics, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360572PMC
March 2017

A novel bifunctional transcriptional regulator of riboflavin metabolism in Archaea.

Nucleic Acids Res 2017 04;45(7):3785-3799

Sanford-Burnham-Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1093/nar/gkw1331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397151PMC
April 2017

Crystal Structure of the Complex of Human FasL and Its Decoy Receptor DcR3.

Structure 2016 11;24(11):2016-2023

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA; Department of Physiology and Biophysics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.str.2016.09.009DOI Listing
November 2016

Co-stimulate or Co-inhibit Regulatory T Cells, Which Side to Go?

Immunol Invest 2016 Nov 15;45(8):813-831. Epub 2016 Jul 15.

b Department of Microbiology and Immunology , Albert Einstein College of Medicine , Bronx , NY , USA.

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http://dx.doi.org/10.1080/08820139.2016.1186690DOI Listing
November 2016

Diversity-Oriented Synthesis as a Strategy for Fragment Evolution against GSK3β.

ACS Med Chem Lett 2016 Sep 14;7(9):852-6. Epub 2016 Jul 14.

Chemical Biology Program, The Broad Institute of Harvard and MIT , 415 Main Street, Cambridge, Massachusetts 02142, United States.

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http://dx.doi.org/10.1021/acsmedchemlett.6b00230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018862PMC
September 2016

A Small Protein Associated with Fungal Energy Metabolism Affects the Virulence of Cryptococcus neoformans in Mammals.

PLoS Pathog 2016 09 1;12(9):e1005849. Epub 2016 Sep 1.

Department of Molecular Microbiology and Immunology, John Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1005849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008624PMC
September 2016

Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars.

Proc Natl Acad Sci U S A 2016 07 11;113(29):E4161-9. Epub 2016 Jul 11.

Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801

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http://dx.doi.org/10.1073/pnas.1605546113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961189PMC
July 2016

GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half-life in a murine model of sickle cell disease.

Br J Haematol 2016 10 5;175(1):141-53. Epub 2016 Jul 5.

Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.1111/bjh.14214DOI Listing
October 2016

Structure of an ABC transporter solute-binding protein specific for the amino sugars glucosamine and galactosamine.

Acta Crystallogr F Struct Biol Commun 2016 06 23;72(Pt 6):467-72. Epub 2016 May 23.

Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1107/S2053230X16007500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909247PMC
June 2016

Durable antitumor responses to CD47 blockade require adaptive immune stimulation.

Proc Natl Acad Sci U S A 2016 May 18;113(19):E2646-54. Epub 2016 Apr 18.

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305

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http://dx.doi.org/10.1073/pnas.1604268113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868409PMC
May 2016

Purification, crystallization and structural elucidation of D-galactaro-1,4-lactone cycloisomerase from Agrobacterium tumefaciens involved in pectin degradation.

Acta Crystallogr F Struct Biol Commun 2016 Jan 1;72(Pt 1):36-41. Epub 2016 Jan 1.

Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1107/S2053230X15023286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708048PMC
January 2016

A General Strategy for the Discovery of Metabolic Pathways: d-Threitol, l-Threitol, and Erythritol Utilization in Mycobacterium smegmatis.

J Am Chem Soc 2015 Nov 12;137(46):14570-3. Epub 2015 Nov 12.

Department of Biochemistry, Albert Einstein College of Medicine , Bronx, New York 10461, United States.

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http://dx.doi.org/10.1021/jacs.5b08968DOI Listing
November 2015

ATP-binding Cassette (ABC) Transport System Solute-binding Protein-guided Identification of Novel d-Altritol and Galactitol Catabolic Pathways in Agrobacterium tumefaciens C58.

J Biol Chem 2015 Nov 15;290(48):28963-76. Epub 2015 Oct 15.

From the Departments of Biochemistry and Chemistry and Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801 and

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http://dx.doi.org/10.1074/jbc.M115.686857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661409PMC
November 2015

Increased Heterologous Protein Expression in Drosophila S2 Cells for Massive Production of Immune Ligands/Receptors and Structural Analysis of Human HVEM.

Mol Biotechnol 2015 Oct;57(10):914-22

Department of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY, 10461, USA.

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http://dx.doi.org/10.1007/s12033-015-9881-2DOI Listing
October 2015

X-ray crystallography over the past decade for novel drug discovery - where are we heading next?

Expert Opin Drug Discov 2015 15;10(9):975-89. Epub 2015 Jul 15.

University of Virginia, Department of Molecular Physiology and Biological Physics , 1340 Jefferson Park Avenue, Charlottesville, VA 22908 , USA +1 434 243 6865 ; +1 434 243 2981 ;

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http://dx.doi.org/10.1517/17460441.2015.1061991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655606PMC
April 2016

Function discovery and structural characterization of a methylphosphonate esterase.

Biochemistry 2015 May 28;54(18):2919-30. Epub 2015 Apr 28.

‡Department of Biochemistry, Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York, 10461, United States.

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http://dx.doi.org/10.1021/acs.biochem.5b00199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477287PMC
May 2015

Determinants of the CmoB carboxymethyl transferase utilized for selective tRNA wobble modification.

Nucleic Acids Res 2015 May 8;43(9):4602-13. Epub 2015 Apr 8.

Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA Department of Physiology & Biophysics, Albert Einstein College of Medicine, Bronx, NY 10461, USA

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http://dx.doi.org/10.1093/nar/gkv206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482062PMC
May 2015

Active site and remote contributions to catalysis in methylthioadenosine nucleosidases.

Biochemistry 2015 Apr 3;54(15):2520-9. Epub 2015 Apr 3.

†Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, United States.

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http://dx.doi.org/10.1021/bi501487wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485437PMC
April 2015

A switch from parallel to antiparallel strand orientation in a coiled-coil X-ray structure via two core hydrophobic mutations.

Biopolymers 2015 May;104(3):178-85

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY, 10461.

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http://dx.doi.org/10.1002/bip.22631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768791PMC
May 2015

A unique cis-3-hydroxy-l-proline dehydratase in the enolase superfamily.

J Am Chem Soc 2015 Feb 26;137(4):1388-91. Epub 2015 Jan 26.

Departments of Biochemistry and Chemistry and ‡Institute for Genomic Biology, University of Illinois at Urbana-Champaign , Urbana, Illinois 61801, United States.

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http://dx.doi.org/10.1021/ja5103986DOI Listing
February 2015

Structure of N-formimino-L-glutamate iminohydrolase from Pseudomonas aeruginosa.

Biochemistry 2015 Jan 16;54(3):890-7. Epub 2015 Jan 16.

Department of Chemistry and ‡Department of Biochemistry & Biophysics, Texas A&M University , College Station, Texas 77843, United States.

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http://dx.doi.org/10.1021/bi501299yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357388PMC
January 2015

Expression, Clinical Significance, and Receptor Identification of the Newest B7 Family Member HHLA2 Protein.

Clin Cancer Res 2015 May 30;21(10):2359-66. Epub 2014 Dec 30.

Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York. Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433806PMC
May 2015

Covalent docking predicts substrates for haloalkanoate dehalogenase superfamily phosphatases.

Biochemistry 2015 Jan 5;54(2):528-37. Epub 2015 Jan 5.

Department of Pharmaceutical Chemistry, and §Department of Bioengineering and Therapeutic Sciences, University of California San Francisco , San Francisco, California 94158, United States.

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http://dx.doi.org/10.1021/bi501140kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303301PMC
January 2015

Structure and cancer immunotherapy of the B7 family member B7x.

Cell Rep 2014 Nov 30;9(3):1089-98. Epub 2014 Oct 30.

Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY 10467, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.09.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250833PMC
November 2014

Discovery of a bacterial 5-methylcytosine deaminase.

Biochemistry 2014 Dec 19;53(47):7426-35. Epub 2014 Nov 19.

Department of Biochemistry & Biophysics and ‡Department of Chemistry, Texas A&M University , College Station, Texas 77843, United States.

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http://dx.doi.org/10.1021/bi5012767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255641PMC
December 2014

Nectin family of cell-adhesion molecules: structural and molecular aspects of function and specificity.

Cell Mol Life Sci 2015 Feb 19;72(4):645-58. Epub 2014 Oct 19.

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10461, USA,

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http://dx.doi.org/10.1007/s00018-014-1763-4DOI Listing
February 2015

Investigating the role of a backbone to substrate hydrogen bond in OMP decarboxylase using a site-specific amide to ester substitution.

Proc Natl Acad Sci U S A 2014 Oct 1;111(42):15066-71. Epub 2014 Oct 1.

Departments of Biochemistry and Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801; Chemistry and

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http://dx.doi.org/10.1073/pnas.1411772111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210302PMC
October 2014

Photoswitchable red fluorescent protein with a large Stokes shift.

Chem Biol 2014 Oct 18;21(10):1402-1414. Epub 2014 Sep 18.

Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Biochemistry and Developmental Biology, Institute of Biomedicine, University of Helsinki, Helsinki 00290, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2014.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224599PMC
October 2014

Investigating the physiological roles of low-efficiency D-mannonate and D-gluconate dehydratases in the enolase superfamily: pathways for the catabolism of L-gulonate and L-idonate.

Biochemistry 2014 Sep 27;53(35):5692-9. Epub 2014 Aug 27.

Departments of Biochemistry and Chemistry and Institute for Genomic Biology, University of Illinois at Urbana-Champaign , Urbana, Illinois 61801, United States.

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http://dx.doi.org/10.1021/bi500837wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159206PMC
September 2014

Integrative structure-function mapping of the nucleoporin Nup133 suggests a conserved mechanism for membrane anchoring of the nuclear pore complex.

Mol Cell Proteomics 2014 Nov 19;13(11):2911-26. Epub 2014 Aug 19.

From the ‡Department of Bioengineering and Therapeutic Sciences, Department of Pharmaceutical Chemistry, California Institute for Quantitative Biosciences, Byers Hall, 1700 4th Street, Suite 503B, University of California San Francisco, San Francisco, California 94158;

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http://dx.doi.org/10.1074/mcp.M114.040915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223481PMC
November 2014

Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly.

Structure 2014 Sep 31;22(9):1252-1262. Epub 2014 Jul 31.

Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address:

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http://dx.doi.org/10.1016/j.str.2014.06.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163024PMC
September 2014

Considerations for combined immune checkpoint modulation and radiation treatment.

Radiat Res 2014 Aug 8;182(2):230-8. Epub 2014 Jul 8.

a  Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461;

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http://dx.doi.org/10.1667/RR13667.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163026PMC
August 2014

l-Galactose metabolism in Bacteroides vulgatus from the human gut microbiota.

Biochemistry 2014 Jul 7;53(28):4661-70. Epub 2014 Jul 7.

Department of Biochemistry and Biophysics, §Department of Chemistry, Texas A&M University , College Station, Texas 77843, United States.

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http://dx.doi.org/10.1021/bi500656mDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108180PMC
July 2014

Orange fluorescent proteins: structural studies of LSSmOrange, PSmOrange and PSmOrange2.

PLoS One 2014 24;9(6):e99136. Epub 2014 Jun 24.

Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068994PMC
November 2015

Identification of the in vivo function of the high-efficiency D-mannonate dehydratase in Caulobacter crescentus NA1000 from the enolase superfamily.

Biochemistry 2014 Jul 20;53(25):4087-9. Epub 2014 Jun 20.

Institute for Genomic Biology, University of Illinois at Urbana-Champaign , Urbana, Illinois 61801, United States.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082379PMC
July 2014

Evolution of enzymatic activities in the enolase superfamily: galactarate dehydratase III from Agrobacterium tumefaciens C58.

Biochemistry 2014 Jul 19;53(25):4192-203. Epub 2014 Jun 19.

Department of Biochemistry, ‡Department of Chemistry, and §Institute for Genomic Biology, University of Illinois at Urbana-Champaign , 600 South Mathews Avenue, Urbana, Illinois 61801, United States.

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http://dx.doi.org/10.1021/bi5005377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081050PMC
July 2014

Discovery of a novel L-lyxonate degradation pathway in Pseudomonas aeruginosa PAO1.

Biochemistry 2014 May 15;53(20):3357-66. Epub 2014 May 15.

Department of Biochemistry, ‡Department of Chemistry, and §Institute for Genomic Biology, University of Illinois at Urbana-Champaign , 600 South Mathews Avenue, Urbana, Illinois 61801, United States.

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http://dx.doi.org/10.1021/bi5004298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038344PMC
May 2014

Substrate deconstruction and the nonadditivity of enzyme recognition.

J Am Chem Soc 2014 May 12;136(20):7374-82. Epub 2014 May 12.

Department of Pharmaceutical Chemistry, University of California - San Francisco , 1700 Fourth Street, Byers Hall, San Francisco, California 94158, United States.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046767PMC
May 2014

Large-scale determination of sequence, structure, and function relationships in cytosolic glutathione transferases across the biosphere.

PLoS Biol 2014 Apr 22;12(4):e1001843. Epub 2014 Apr 22.

Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, California, United States of America; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, United States of America; California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, California, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995644PMC
April 2014

Influence of a heptad repeat stutter on the pH-dependent conformational behavior of the central coiled-coil from influenza hemagglutinin HA2.

Proteins 2014 Sep 6;82(9):2220-8. Epub 2014 May 6.

Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NewYork, 10461.

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http://dx.doi.org/10.1002/prot.24585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142070PMC
September 2014

Better and faster: improvements and optimization for mammalian recombinant protein production.

Curr Opin Struct Biol 2014 Jun 12;26:39-43. Epub 2014 Apr 12.

Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, United States. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766836PMC
June 2014