Steven B Mizel

Steven B Mizel

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Steven B Mizel

Steven B Mizel

Publications by authors named "Steven B Mizel"

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21Publications

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Parainfluenza virus 5-based vaccine vectors expressing vaccinia virus (VACV) antigens provide long-term protection in mice from lethal intranasal VACV challenge.

Virology 2011 Oct 31;419(2):97-106. Epub 2011 Aug 31.

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1064, USA.

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http://dx.doi.org/10.1016/j.virol.2011.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177979PMC
October 2011

Enhanced antigen processing of flagellin fusion proteins promotes the antigen-specific CD8+ T cell response independently of TLR5 and MyD88.

J Immunol 2011 Jun 22;186(11):6255-62. Epub 2011 Apr 22.

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.4049/jimmunol.1001855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743533PMC
June 2011

Stimulation of human dendritic cells by wild-type and M protein mutant vesicular stomatitis viruses engineered to express bacterial flagellin.

J Virol 2010 Nov 15;84(22):12093-8. Epub 2010 Sep 15.

Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1128/JVI.00406-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977888PMC
November 2010

Flagellin as an adjuvant: cellular mechanisms and potential.

J Immunol 2010 Nov;185(10):5677-82

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.4049/jimmunol.1002156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756556PMC
November 2010

Protection against lethal vaccinia virus challenge by using an attenuated matrix protein mutant vesicular stomatitis virus vaccine vector expressing poxvirus antigens.

J Virol 2010 Apr 20;84(7):3552-61. Epub 2010 Jan 20.

Department of Biochemistry, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1128/JVI.01572-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838111PMC
April 2010

A recombinant flagellin-poxvirus fusion protein vaccine elicits complement-dependent protection against respiratory challenge with vaccinia virus in mice.

Viral Immunol 2010 Apr;23(2):201-10

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.

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http://dx.doi.org/10.1089/vim.2009.0107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883514PMC
April 2010

Immunization of young African green monkeys with OprF epitope 8-OprI-type A- and B-flagellin fusion proteins promotes the production of protective antibodies against nonmucoid Pseudomonas aeruginosa.

Vaccine 2009 Nov 8;27(48):6762-9. Epub 2009 Sep 8.

Department of Microbiology & Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.vaccine.2009.08.080DOI Listing
November 2009

A fusion protein vaccine containing OprF epitope 8, OprI, and type A and B flagellins promotes enhanced clearance of nonmucoid Pseudomonas aeruginosa.

Infect Immun 2009 Jun 6;77(6):2356-66. Epub 2009 Apr 6.

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1128/IAI.00054-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687341PMC
June 2009

Direct stimulation of tlr5+/+ CD11c+ cells is necessary for the adjuvant activity of flagellin.

J Immunol 2009 Jun;182(12):7539-47

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.4049/jimmunol.0804225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770462PMC
June 2009

Flagellin-F1-V fusion protein is an effective plague vaccine in mice and two species of nonhuman primates.

Clin Vaccine Immunol 2009 Jan 5;16(1):21-8. Epub 2008 Nov 5.

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157-1064, USA.

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http://dx.doi.org/10.1128/CVI.00333-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2620661PMC
January 2009

Engineered expression of the TLR5 ligand flagellin enhances paramyxovirus activation of human dendritic cell function.

J Virol 2008 Nov 10;82(22):10975-85. Epub 2008 Sep 10.

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157-1064, USA.

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http://dx.doi.org/10.1128/JVI.01288-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573257PMC
November 2008

Mucosal adjuvant activity of flagellin in aged mice.

Mech Ageing Dev 2008 May 17;129(5):271-81. Epub 2008 Feb 17.

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.mad.2008.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366812PMC
May 2008

Effects of flagellin on innate and adaptive immunity.

Immunol Res 2005 ;33(1):83-101

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.

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http://dx.doi.org/10.1385/IR:33:1:083DOI Listing
March 2008

Flagellin is an effective adjuvant for immunization against lethal respiratory challenge with Yersinia pestis.

Infect Immun 2006 Feb;74(2):1113-20

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157, USA.

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http://iai.asm.org/cgi/doi/10.1128/IAI.74.2.1113-1120.2006
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http://dx.doi.org/10.1128/IAI.74.2.1113-1120.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360354PMC
February 2006

Gangliosides inhibit flagellin signaling in the absence of an effect on flagellin binding to toll-like receptor 5.

J Biol Chem 2005 Mar 4;280(10):9482-8. Epub 2005 Jan 4.

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.

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http://dx.doi.org/10.1074/jbc.M411875200DOI Listing
March 2005

Mucosal administration of flagellin induces innate immunity in the mouse lung.

Infect Immun 2004 Nov;72(11):6676-9

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1128/IAI.72.11.6676-6679.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC523048PMC
November 2004

Identification of a sequence in human toll-like receptor 5 required for the binding of Gram-negative flagellin.

J Biol Chem 2003 Jun 23;278(26):23624-9. Epub 2003 Apr 23.

Department of Microbiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.

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http://dx.doi.org/10.1074/jbc.M303481200DOI Listing
June 2003

Induction of macrophage nitric oxide production by Gram-negative flagellin involves signaling via heteromeric Toll-like receptor 5/Toll-like receptor 4 complexes.

J Immunol 2003 Jun;170(12):6217-23

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.4049/jimmunol.170.12.6217DOI Listing
June 2003

Gram-negative flagellin-induced self-tolerance is associated with a block in interleukin-1 receptor-associated kinase release from toll-like receptor 5.

J Biol Chem 2002 Jun 12;277(25):22414-20. Epub 2002 Apr 12.

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.

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http://dx.doi.org/10.1074/jbc.M201762200DOI Listing
June 2002