Steven A Roberts

Steven A Roberts

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Steven A Roberts

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Corrigendum to "APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast" [DNA Repair 53 (2017) 4-14].

DNA Repair (Amst) 2019 Aug 7;80:94-95. Epub 2019 Jun 7.

Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle Park, NC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.dnarep.2019.05.006DOI Listing
August 2019

Repair of base damage within break-induced replication intermediates promotes kataegis associated with chromosome rearrangements.

Nucleic Acids Res 2019 Aug 8. Epub 2019 Aug 8.

Department of Biology, University of Iowa, Iowa City, IA 52245, USA.

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http://dx.doi.org/10.1093/nar/gkz651DOI Listing
August 2019

Survival after lobectomy versus sub-lobar resection in elderly with stage I NSCLC: a meta-analysis.

BMC Surg 2019 Apr 15;19(1):38. Epub 2019 Apr 15.

Department of Thoracic Surgery, First Hospital of China Medical University, 155 North Nanjing Street, Shenyang, Liaoning, China.

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http://dx.doi.org/10.1186/s12893-019-0500-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466711PMC
April 2019

High-Throughput Analysis of DNA Break-Induced Chromosome Rearrangements by Amplicon Sequencing.

Methods Enzymol 2018 21;601:111-144. Epub 2018 Feb 21.

School of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, WA, United States; Center for Reproductive Biology, College of Veterinary Medicine, Washington State University, Pullman, WA, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2017.11.028DOI Listing
March 2019

Recurrent Noncoding Mutations in Skin Cancers: UV Damage Susceptibility or Repair Inhibition as Primary Driver?

Bioessays 2019 03 25;41(3):e1800152. Epub 2019 Feb 25.

School of Molecular Biosciences and Center for Reproductive Biology, Washington State University, Pullman, Washington, 99164.

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http://dx.doi.org/10.1002/bies.201800152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571124PMC
March 2019

Using Yeast as a Model Organism to Study the Functional Roles of Histone Acetylation in DNA Excision Repair.

Methods Mol Biol 2019 ;1983:175-190

School of Molecular Biosciences, Washington State University, Pullman, WA, USA.

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http://dx.doi.org/10.1007/978-1-4939-9434-2_10DOI Listing
January 2019

SPIN: rapid synthesis, purification, and concentration of small drug-loaded liposomes.

J Liposome Res 2018 Dec 5;28(4):331-340. Epub 2017 Oct 5.

a Department of Bioengineering , George Mason University , Fairfax , VA , USA.

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http://dx.doi.org/10.1080/08982104.2017.1381115DOI Listing
December 2018

Nucleosome positions establish an extended mutation signature in melanoma.

PLoS Genet 2018 11 28;14(11):e1007823. Epub 2018 Nov 28.

School of Molecular Biosciences, Washington State University, Pullman, WA, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287878PMC
November 2018

Analysis of Drosophila STING Reveals an Evolutionarily Conserved Antimicrobial Function.

Cell Rep 2018 06;23(12):3537-3550.e6

School of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA; Paul G. Allen School for Global Animal Health, College of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.05.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114933PMC
June 2018

Secondary structure forming sequences drive SD-MMEJ repair of DNA double-strand breaks.

Nucleic Acids Res 2017 Dec;45(22):12848-12861

Department of Biology, Tufts University, 200 Boston Avenue, Suite 4700, Medford, MA 02155, USA.

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http://dx.doi.org/10.1093/nar/gkx1056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728401PMC
December 2017

"Data characterizing microfabricated human blood vessels created via hydrodynamic focusing".

Data Brief 2017 Oct 15;14:156-162. Epub 2017 Jul 15.

Center for Bio/Molecular Science & Engineering US Naval Research Laboratory, 4555 Overlook Ave. SW, Washington D.C. 20375, United States.

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http://dx.doi.org/10.1016/j.dib.2017.07.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545875PMC
October 2017

Genome-wide maps of alkylation damage, repair, and mutagenesis in yeast reveal mechanisms of mutational heterogeneity.

Genome Res 2017 10 14;27(10):1674-1684. Epub 2017 Sep 14.

School of Molecular Biosciences, Washington State University, Pullman, Washington 99164, USA.

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http://dx.doi.org/10.1101/gr.225771.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630031PMC
October 2017

Rapid Generation and Detection of Biomimetic Oxygen Concentration Gradients In Vitro.

Sci Rep 2017 10 18;7(1):13487. Epub 2017 Oct 18.

Bioengineering Department, George Mason University, Fairfax, 22030, USA.

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http://dx.doi.org/10.1038/s41598-017-13886-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647399PMC
October 2017

Microfabricated blood vessels undergo neoangiogenesis.

Biomaterials 2017 Sep 19;138:142-152. Epub 2017 May 19.

Center for Bio/Molecular Science & Engineering, U.S. Naval Research Laboratory, 4555 Overlook Ave. SW, Washington D.C., 20375, United States. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2017.05.012DOI Listing
September 2017

Avoidance of APOBEC3B-induced mutation by error-free lesion bypass.

Nucleic Acids Res 2017 May;45(9):5243-5254

School of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA.

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http://dx.doi.org/10.1093/nar/gkx169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605239PMC
May 2017

APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast.

DNA Repair (Amst) 2017 05 21;53:4-14. Epub 2017 Mar 21.

Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle Park, NC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.dnarep.2017.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450012PMC
May 2017

UV-Induced DNA Damage and Mutagenesis in Chromatin.

Photochem Photobiol 2017 01 7;93(1):216-228. Epub 2016 Nov 7.

School of Molecular Biosciences, Washington State University, Pullman, WA.

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http://dx.doi.org/10.1111/php.12646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315636PMC
January 2017

Risks at the DNA Replication Fork: Effects upon Carcinogenesis and Tumor Heterogeneity.

Genes (Basel) 2017 Jan 22;8(1). Epub 2017 Jan 22.

School of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA.

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http://dx.doi.org/10.3390/genes8010046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295039PMC
January 2017

The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts.

PLoS Genet 2016 10 27;12(10):e1006385. Epub 2016 Oct 27.

Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle Park, North Carolina, United States Of America.

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http://dx.doi.org/10.1371/journal.pgen.1006385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082821PMC
October 2016

Microvessel manifold for perfusion and media exchange in three-dimensional cell cultures.

Biomicrofluidics 2016 Sep 23;10(5):054109. Epub 2016 Sep 23.

Center for Bio/Molecular Science and Engineering , U.S. Naval Research Laboratory, 4555 Overlook Ave., Washington, DC 20375, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035297PMC
http://dx.doi.org/10.1063/1.4963145DOI Listing
September 2016

Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.

Mol Cell 2016 08 21;63(4):662-673. Epub 2016 Jul 21.

Lineberger Comprehensive Cancer Center, Curriculum in Genetics and Molecular Biology, and Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27599, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.06.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992412PMC
August 2016

Chromosomal landscape of UV damage formation and repair at single-nucleotide resolution.

Proc Natl Acad Sci U S A 2016 08 25;113(32):9057-62. Epub 2016 Jul 25.

School of Molecular Biosciences, Washington State University, Pullman, WA 99164; Center for Reproductive Biology, Washington State University, Pullman, WA 99164

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http://dx.doi.org/10.1073/pnas.1606667113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987812PMC
August 2016

Development of a Single-Cell Migration and Extravasation Platform through Selective Surface Modification.

Anal Chem 2016 Mar 11;88(5):2770-6. Epub 2016 Feb 11.

Department of Bioengineering, George Mason University , Fairfax, Virginia 22030, United States.

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http://pubs.acs.org/doi/10.1021/acs.analchem.5b04391
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http://dx.doi.org/10.1021/acs.analchem.5b04391DOI Listing
March 2016

APOBEC3A and APOBEC3B Preferentially Deaminate the Lagging Strand Template during DNA Replication.

Cell Rep 2016 Feb 28;14(6):1273-1282. Epub 2016 Jan 28.

School of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.01.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758883PMC
February 2016

Genomic approaches to DNA repair and mutagenesis.

DNA Repair (Amst) 2015 Dec 15;36:146-155. Epub 2015 Sep 15.

School of Molecular Biosciences, Washington State University, Pullman, WA 99164, USA. Electronic address:

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http://dx.doi.org/10.1016/j.dnarep.2015.09.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688168PMC
December 2015

An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers.

Nat Genet 2015 Sep 10;47(9):1067-72. Epub 2015 Aug 10.

Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle Park, North Carolina, USA.

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http://dx.doi.org/10.1038/ng.3378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594173PMC
September 2015

Sweet substrate: a polysaccharide nanocomposite for conformal electronic decals.

Adv Mater 2015 Mar 3;27(9):1600-6. Epub 2014 Dec 3.

Center for Bio/Molecular Science and Engineering, U.S. Naval Research Laboratory, 4555 Overlook Ave. SW, Washington, D.C. 20375, USA.

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http://dx.doi.org/10.1002/adma.201404445DOI Listing
March 2015

Requirements for 5'dRP/AP lyase activity in Ku.

Nucleic Acids Res 2014 8;42(17):11136-43. Epub 2014 Sep 8.

Lineberger Comprehensive Cancer Center, Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27514, USA Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC 27599, USA

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http://dx.doi.org/10.1093/nar/gku796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176175PMC
February 2015

Break-induced replication is a source of mutation clusters underlying kataegis.

Cell Rep 2014 Jun 29;7(5):1640-1648. Epub 2014 May 29.

Department of Biology, College of Liberal Arts and Sciences, University of Iowa, Iowa City, IA 52242-1324, USA; Department of Biology, School of Science, IUPUI, Indianapolis, IN 46202-5132, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.04.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274036PMC
June 2014

Clustered and genome-wide transient mutagenesis in human cancers: Hypermutation without permanent mutators or loss of fitness.

Bioessays 2014 04 26;36(4):382-393. Epub 2014 Feb 26.

Chromosome Stability Group, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Durham, NC, USA.

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http://dx.doi.org/10.1002/bies.201300140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145046PMC
April 2014

Base damage within single-strand DNA underlies in vivo hypermutability induced by a ubiquitous environmental agent.

PLoS Genet 2012 13;8(12):e1003149. Epub 2012 Dec 13.

Chromosome Stability Section, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1003149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521656PMC
May 2013

Specificity of the dRP/AP lyase of Ku promotes nonhomologous end joining (NHEJ) fidelity at damaged ends.

J Biol Chem 2012 Apr 23;287(17):13686-93. Epub 2012 Feb 23.

Lineberger Comprehensive Cancer Center, Department of Biochemistry and Biophysics and Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1074/jbc.M111.329730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340204PMC
April 2012

Damage-induced localized hypermutability.

Cell Cycle 2011 Apr 1;10(7):1073-85. Epub 2011 Apr 1.

National Institute of Environmental Health Sciences, Research Triangle Park, NC USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100884PMC
http://dx.doi.org/10.4161/cc.10.7.15319DOI Listing
April 2011

Ku is a 5'-dRP/AP lyase that excises nucleotide damage near broken ends.

Nature 2010 Apr 11;464(7292):1214-7. Epub 2010 Apr 11.

Department of Biochemistry and Biophysics, Lineberger Comprehensive Cancer Center, and Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1038/nature08926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859099PMC
April 2010

Activity of ribonucleotide reductase helps determine how cells repair DNA double strand breaks.

DNA Repair (Amst) 2009 Nov 26;8(11):1258-63. Epub 2009 Aug 26.

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States.

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http://dx.doi.org/10.1016/j.dnarep.2009.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763971PMC
November 2009

Toxicodynamics of itraconazole: implications for therapeutic drug monitoring.

Clin Infect Dis 2009 Sep;49(6):928-30

The University of Manchester, Manchester Academic Health Science Centre, NIHR Translational Research Facility in Respiratory Medicine, University Hospital of South Manchester NHS Foundation Trust, Manchester, UK.

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http://dx.doi.org/10.1086/605499DOI Listing
September 2009

Loading of the nonhomologous end joining factor, Ku, on protein-occluded DNA ends.

J Biol Chem 2007 Apr 8;282(14):10605-13. Epub 2007 Feb 8.

Lineberger Comprehensive Cancer Center and Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1074/jbc.M611125200DOI Listing
April 2007

UK reference data for the Hologic QDR Discovery dual-energy x ray absorptiometry scanner in healthy children and young adults aged 6-17 years.

Arch Dis Child 2007 Jan 30;92(1):53-9. Epub 2006 Aug 30.

Department of Clinical Radiology, Imaging Science and Biomedical Engineering, University of Manchester, Manchester, UK.

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http://adc.bmj.com/cgi/doi/10.1136/adc.2006.097642
Publisher Site
http://dx.doi.org/10.1136/adc.2006.097642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2083173PMC
January 2007

Caudal injectate can be reliably imaged using portable ultrasound--a preliminary study.

Paediatr Anaesth 2005 Nov;15(11):948-52

Jackson Rees Department of Anaesthesia, The Royal Liverpool Children's NHS Trust, Alder Hey Hospital, Liverpool, UK.

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http://dx.doi.org/10.1111/j.1460-9592.2005.01606.xDOI Listing
November 2005