Steven A Goldman

Steven A Goldman

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Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation.

Cell Stem Cell 2019 Oct;25(4):531-541.e6

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2019.09.003DOI Listing
October 2019

Human Glial Chimeric Mice to Define the Role of Glial Pathology in Human Disease.

Methods Mol Biol 2019 ;1936:311-331

Department of Neurology and the Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY, USA.

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http://dx.doi.org/10.1007/978-1-4939-9072-6_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700730PMC
July 2019

Dysregulated Glial Differentiation in Schizophrenia May Be Relieved by Suppression of SMAD4- and REST-Dependent Signaling.

Cell Rep 2019 Jun;27(13):3832-3843.e6

Center for Translational Neuromedicine and Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA; Center for Neuroscience, University of Copenhagen Faculty of Health and Medical Sciences, 2200 Copenhagen N, Denmark; Neuroscience Center, Rigshospitalet, Copenhagen, Denmark. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247193072
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http://dx.doi.org/10.1016/j.celrep.2019.05.088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700735PMC
June 2019

Astrocytic connexin 43 potentiates myelin injury in ischemic white matter disease.

Theranostics 2019 9;9(15):4474-4493. Epub 2019 Jun 9.

Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

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http://dx.doi.org/10.7150/thno.31942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599652PMC
June 2019

Human ESC-Derived Chimeric Mouse Models of Huntington's Disease Reveal Cell-Intrinsic Defects in Glial Progenitor Cell Differentiation.

Cell Stem Cell 2019 01 13;24(1):107-122.e7. Epub 2018 Dec 13.

Center for Translational Neuromedicine, University of Copenhagen Faculty of Health and Medical Science, 2200 Copenhagen N, Denmark; Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY 10021, USA; Neuroscience Center, Rigshospitalet, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2018.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700734PMC
January 2019

Neurogenetics of Pelizaeus-Merzbacher disease.

Handb Clin Neurol 2018 ;148:701-722

Center for Translational Neuromedicine and Department of Neurology, University of Rochester Medical Center, Rochester, NY, United States; Center for Translational Neuromedicine, University of Copenhagen Faculty of Health and Medical Sciences, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/B978-0-444-64076-5.00045-4DOI Listing
August 2018

Progenitor cell-based treatment of glial disease.

Authors:
Steven A Goldman

Prog Brain Res 2017 13;231:165-189. Epub 2017 Apr 13.

Center for Neuroscience, University of Copenhagen Faculty of Health and Medical Sciences, Copenhagen, Denmark; Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.pbr.2017.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662136PMC
May 2018

Transplanted neural progenitors bridge gaps to benefit cord-injured monkeys.

Authors:
Steven A Goldman

Nat Med 2018 04;24(4):388-390

Center for Translational Neuromedicine, University of Rochester, Rochester, New York, USA and in the Center for Translational Neuromedicine, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/nm.4531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700721PMC
April 2018

Patience pays in spinal repair.

Authors:
Steven A Goldman

J Clin Invest 2017 09 21;127(9):3284-3286. Epub 2017 Aug 21.

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http://dx.doi.org/10.1172/JCI96650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669576PMC
September 2017

Human iPSC Glial Mouse Chimeras Reveal Glial Contributions to Schizophrenia.

Cell Stem Cell 2017 08 20;21(2):195-208.e6. Epub 2017 Jul 20.

Department of Neurology and Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY 14642, USA; Center for Neuroscience, University of Copenhagen Faculty of Health and Medical Sciences, 2200 Copenhagen N, Denmark; Neuroscience Center, Rigshospitalet, 2100 Copenhagen, Denmark. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19345909173023
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http://dx.doi.org/10.1016/j.stem.2017.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576346PMC
August 2017

Unravelling and Exploiting Astrocyte Dysfunction in Huntington's Disease.

Trends Neurosci 2017 07 31;40(7):422-437. Epub 2017 May 31.

Exzellenzcluster NeuroCure & Abt. Experimentelle Neurologie, Charité - Universitätsmedizin Berlin, Robert-Koch-Platz 4, D-10115 Berlin, Germany.

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http://dx.doi.org/10.1016/j.tins.2017.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706770PMC
July 2017

Modeling the Mutational and Phenotypic Landscapes of Pelizaeus-Merzbacher Disease with Human iPSC-Derived Oligodendrocytes.

Am J Hum Genet 2017 Apr 30;100(4):617-634. Epub 2017 Mar 30.

Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384098PMC
April 2017

Concise Review: Stem Cell-Based Treatment of Pelizaeus-Merzbacher Disease.

Stem Cells 2017 02 23;35(2):311-315. Epub 2016 Nov 23.

Center for Basic and Translational Neuroscience, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/stem.2530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314962PMC
February 2017

Zika Virus NS4A and NS4B Proteins Deregulate Akt-mTOR Signaling in Human Fetal Neural Stem Cells to Inhibit Neurogenesis and Induce Autophagy.

Cell Stem Cell 2016 11 11;19(5):663-671. Epub 2016 Aug 11.

Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2016.07.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144538PMC
November 2016

Glial progenitor cell-based treatment of the childhood leukodystrophies.

Exp Neurol 2016 09 8;283(Pt B):476-88. Epub 2016 May 8.

Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY 14642, United States; Center for Basic and Translational Neuroscience, University of Copenhagen Faculty of Health and Medical Sciences, Copenhagen 2200, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2016.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340082PMC
September 2016

3K3A-activated protein C stimulates postischemic neuronal repair by human neural stem cells in mice.

Nat Med 2016 09 22;22(9):1050-5. Epub 2016 Aug 22.

Department of Physiology and Biophysics, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.

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http://dx.doi.org/10.1038/nm.4154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215920PMC
September 2016

Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation.

Nat Commun 2016 Mar 9;7:10883. Epub 2016 Mar 9.

Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.

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http://dx.doi.org/10.1038/ncomms10883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786870PMC
March 2016

Stem and Progenitor Cell-Based Therapy of the Central Nervous System: Hopes, Hype, and Wishful Thinking.

Authors:
Steven A Goldman

Cell Stem Cell 2016 Feb;18(2):174-88

Center for Translational Neuromedicine and the Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA; Center for Basic and Translational Neuroscience, University of Copenhagen Faculty of Health and Medical Sciences, Copenhagen 2200, Denmark. Electronic address:

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http://www.cell.com/cell-stem-cell/pdf/S1934-5909(16)00013-8
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http://linkinghub.elsevier.com/retrieve/pii/S193459091600013
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http://dx.doi.org/10.1016/j.stem.2016.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310249PMC
February 2016

Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch.

Dev Cell 2016 Feb;36(3):316-30

Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Key Laboratory of Birth Defects, Children's Hospital of Fudan University, Shanghai 201102, China. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2016.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750051PMC
February 2016

Purinergic receptor P2RY12-dependent microglial closure of the injured blood-brain barrier.

Proc Natl Acad Sci U S A 2016 Jan 11;113(4):1074-9. Epub 2016 Jan 11.

Center for Translational Neuromedicine, University of Rochester Medical School, Rochester, NY 14642; Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark

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http://dx.doi.org/10.1073/pnas.1520398113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743790PMC
January 2016

How to make an oligodendrocyte.

Development 2015 Dec;142(23):3983-95

Center for Translational Neuromedicine and the Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1242/dev.126409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712837PMC
December 2015

Implications of the discovery of brain lymphatic pathways.

Lancet Neurol 2015 Oct;14(10):977-9

Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY, USA; Center for Basic and Translational Neuroscience, University of Copenhagen, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(15)00221-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655610PMC
October 2015

Modeling cognition and disease using human glial chimeric mice.

Glia 2015 Aug 24;63(8):1483-93. Epub 2015 May 24.

Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, New York.

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http://dx.doi.org/10.1002/glia.22862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527525PMC
August 2015

A Distinct Population of Microglia Supports Adult Neurogenesis in the Subventricular Zone.

J Neurosci 2015 Aug;35(34):11848-61

Center for Translational Neuromedicine, University of Rochester Medical School, Rochester, New York 14642, and Center for Basic and Translational Neuroscience, University of Copenhagen, 2200N Copenhagen, Denmark

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http://dx.doi.org/10.1523/JNEUROSCI.1217-15.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549398PMC
August 2015

Glia Disease and Repair-Remyelination.

Cold Spring Harb Perspect Biol 2015 May 18;7(7):a020594. Epub 2015 May 18.

Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, New York 14642 University of Copenhagen Faculty of Medicine, Copenhagen 2200, Denmark.

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http://cshperspectives.cshlp.org/lookup/doi/10.1101/cshpersp
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http://dx.doi.org/10.1101/cshperspect.a020594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484968PMC
May 2015

Disease specific therapies in leukodystrophies and leukoencephalopathies.

Mol Genet Metab 2015 Apr 7;114(4):527-36. Epub 2015 Feb 7.

Department of Neurology, Children's National Health System, Washington, DC, USA; Center for Genetic Medicine Research, Children's National Health System, Washington, DC USA; Department of Integrated Systems Biology, George Washington University School of Medicine, Washington, DC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2015.01.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390468PMC
April 2015

A competitive advantage by neonatally engrafted human glial progenitors yields mice whose brains are chimeric for human glia.

J Neurosci 2014 Nov;34(48):16153-61

Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, New York 14642, and Center for Basic and Translational Neuroscience, University of Copenhagen Faculty of Medicine, 2200 Copenhagen N, Denmark

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http://dx.doi.org/10.1523/JNEUROSCI.1510-14.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244478PMC
November 2014

Fine-tuning the central nervous system: microglial modelling of cells and synapses.

Philos Trans R Soc Lond B Biol Sci 2014 Oct;369(1654):20130593

Center for Translational Neuromedicine, University of Rochester Medical School, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1098/rstb.2013.0593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173279PMC
October 2014

Stem cell therapy. Use of differentiated pluripotent stem cells as replacement therapy for treating disease.

Science 2014 Aug;345(6199):1247391

Division of Immunogenetics, Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1126/science.1247391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329726PMC
August 2014

So many progenitors, so little myelin.

Nat Neurosci 2014 Apr;17(4):483-5

Center for Translational Neuromedicine and the Department of Neurology of the University of Rochester Medical Center, Rochester, New York, USA.

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http://dx.doi.org/10.1038/nn.3685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121858PMC
April 2014

White matter from fibroblasts.

Authors:
Steven A Goldman

Nat Biotechnol 2013 May;31(5):412-3

Center for Translational Neuromedicine and the Department of Neurology at the University of Rochester Medical Center, Rochester, New York, USA.

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http://dx.doi.org/10.1038/nbt.2570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121857PMC
May 2013

An activated protein C analog stimulates neuronal production by human neural progenitor cells via a PAR1-PAR3-S1PR1-Akt pathway.

J Neurosci 2013 Apr;33(14):6181-90

Center for Neurodegeneration and Regeneration, Zilkha Neurogenetic Institute and Department of Physiology and Biophysics, University of Southern California, Keck School of Medicine, Los Angeles, California 90089, USA.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.4491-12.2
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http://dx.doi.org/10.1523/JNEUROSCI.4491-12.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707621PMC
April 2013

Glial progenitor cell-based treatment and modeling of neurological disease.

Science 2012 Oct;338(6106):491-5

Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1126/science.1218071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548656PMC
October 2012

Heterogeneity of astrocytic form and function.

Methods Mol Biol 2012 ;814:23-45

Center for Translational Neuromedicine, Department of Neurology, University of Rochester Medical Center, Rochester, NY, USA.

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http://link.springer.com/10.1007/978-1-61779-452-0_3
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http://dx.doi.org/10.1007/978-1-61779-452-0_3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506190PMC
March 2012

Cellular therapy and induced neuronal replacement for Huntington's disease.

Neurotherapeutics 2011 Oct;8(4):577-90

Department of Neurology, Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY, USA.

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http://dx.doi.org/10.1007/s13311-011-0075-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250300PMC
October 2011

Perivascular instruction of cell genesis and fate in the adult brain.

Nat Neurosci 2011 Oct 26;14(11):1382-9. Epub 2011 Oct 26.

Department of Neurology and the Center for Translational Neuromedicine, University of Rochester Medical School, Rochester, New York, USA.

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http://dx.doi.org/10.1038/nn.2963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655803PMC
October 2011

CD140a identifies a population of highly myelinogenic, migration-competent and efficiently engrafting human oligodendrocyte progenitor cells.

Nat Biotechnol 2011 Sep 25;29(10):934-41. Epub 2011 Sep 25.

Department of Neurology, University of Rochester Medical Center, Rochester, New York, USA.

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http://dx.doi.org/10.1038/nbt.1972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365580PMC
September 2011

Progenitor cell-based treatment of the pediatric myelin disorders.

Authors:
Steven A Goldman

Arch Neurol 2011 Jul 14;68(7):848-56. Epub 2011 Mar 14.

Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1001/archneurol.2011.46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358919PMC
July 2011

Adrenoceptors in brain: cellular gene expression and effects on astrocytic metabolism and [Ca(2+)]i.

Neurochem Int 2010 Nov 7;57(4):411-20. Epub 2010 Apr 7.

Department of Clinical Pharmacology, College of Basic Medical Sciences, China Medical University, Shenyang, PR China.

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http://dx.doi.org/10.1016/j.neuint.2010.03.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2934885PMC
November 2010

5-HT2B receptors are expressed on astrocytes from brain and in culture and are a chronic target for all five conventional 'serotonin-specific reuptake inhibitors'.

Neuron Glia Biol 2010 May 16;6(2):113-25. Epub 2010 Sep 16.

Department of Clinical Pharmacology, College of Basic Medical Sciences, China Medical University, Shenyang, P.R. China.

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http://dx.doi.org/10.1017/S1740925X10000141DOI Listing
May 2010

Fate determination of adult human glial progenitor cells.

Neuron Glia Biol 2009 Nov 7;5(3-4):45-55. Epub 2009 Oct 7.

Center for Translational Neuromedicine, and the Department of Neurology, University of Rochester Medical Center, Rochester, NY, USA.

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http://dx.doi.org/10.1017/S1740925X09990317DOI Listing
November 2009

Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury.

Proc Natl Acad Sci U S A 2009 Jul 27;106(30):12489-93. Epub 2009 Jul 27.

Department of Neurosurgery, Division of Glial Disease and Therapeutics, Center for Translational Neuromedicine, University of Rochester Medical Center, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1073/pnas.0902531106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718350PMC
July 2009

Prospects of cell therapy for disorders of myelin.

Ann N Y Acad Sci 2008 Oct;1142:218-49

Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah-Hebrew University Hospital, Jerusalem, Israel.

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http://dx.doi.org/10.1196/annals.1444.014DOI Listing
October 2008

Interview. From canaries to the clinic.

Authors:
Steven A Goldman

Regen Med 2008 Sep;3(5):655-9

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http://dx.doi.org/10.2217/17460751.3.5.655DOI Listing
September 2008

A niche-defying feat: induced oligoneogenesis in the adult dentate gyrus.

Cell Stem Cell 2008 Aug;3(2):125-6

Department of Neurology, University of Rochester Medical Center, Rochester, NY 14580, USA.

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http://dx.doi.org/10.1016/j.stem.2008.07.006DOI Listing
August 2008

Statin treatment of adult human glial progenitors induces PPAR gamma-mediated oligodendrocytic differentiation.

Glia 2008 Jul;56(9):954-62

Department of Neurology, University of Rochester Medical Center, New York 14642, USA.

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http://dx.doi.org/10.1002/glia.20669DOI Listing
July 2008

Stem cell-based strategies for treating pediatric disorders of myelin.

Hum Mol Genet 2008 Apr;17(R1):R76-83

Division of Cell and Gene Therapy and Center for Translational Neuromedicine, Department of Neurology and Neurosurgery, University of Rochester Medical Center, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1093/hmg/ddn052DOI Listing
April 2008

Retrovirally mediated telomerase immortalization of neural progenitor cells.

Nat Protoc 2007 ;2(11):2815-25

Department of Neurology, Weill Medical College of Cornell University, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nprot.2007.402DOI Listing
February 2008

The transcriptome and metabolic gene signature of protoplasmic astrocytes in the adult murine cortex.

J Neurosci 2007 Nov;27(45):12255-66

Division of Glial Disease and Therapeutics, Department of Neurosurgery, University of Rochester Medical Center, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.3404-07.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673251PMC
November 2007

Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease.

J Clin Invest 2007 Oct;117(10):2889-902

Department of Neurology, University of Rochester Medical Center, Rochester, New York, USA.

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http://dx.doi.org/10.1172/JCI31778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1978427PMC
October 2007

Angiogenic inhibition reduces germinal matrix hemorrhage.

Nat Med 2007 Apr 1;13(4):477-85. Epub 2007 Apr 1.

Department of Pediatrics, New York Medical College-Westchester Medical Center, Valhalla, New York 10595, USA.

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http://dx.doi.org/10.1038/nm1558DOI Listing
April 2007

Glial progenitor-based repair of demyelinating neurological diseases.

Neurosurg Clin N Am 2007 Jan;18(1):93-104, x

Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue, M779, PO Box 0470, San Francisco, CA 94143-0470, USA.

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http://dx.doi.org/10.1016/j.nec.2006.10.009DOI Listing
January 2007

Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes.

Nat Med 2006 Nov 22;12(11):1259-68. Epub 2006 Oct 22.

Department of Neurology, Weill Medical College of Cornell University, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nm1495DOI Listing
November 2006

Neurocytoma is a tumor of adult neuronal progenitor cells.

J Neurosci 2006 Nov;26(48):12544-55

Department of Neurology, University of Rochester Medical Center, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.0829-06.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6674894PMC
November 2006

Cell replacement therapy in neurological disease.

Philos Trans R Soc Lond B Biol Sci 2006 Sep;361(1473):1463-75

Division of Cell and Gene Therapy, Department of Neurology, University of Rochester Medical Center, 601 Elmwood Avenue, PO Box 645, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1098/rstb.2006.1886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1664668PMC
September 2006

Enhancer-specified GFP-based FACS purification of human spinal motor neurons from embryonic stem cells.

Exp Neurol 2005 Dec 29;196(2):224-34. Epub 2005 Sep 29.

Department of Neurology, Cornell University Medical College, NYC, NY 10021, USA.

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http://dx.doi.org/10.1016/j.expneurol.2005.06.021DOI Listing
December 2005

Neural progenitor cells of the adult brain.

Novartis Found Symp 2005 ;265:66-80; discussion 82-97

Department of Neurology, University of Rochester Medical Center, 601 Elmwood Avenue, MRBX, Box 645, Rochester, NY 14642, USA.

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August 2005

Identification of a conserved 125 base-pair Hb9 enhancer that specifies gene expression to spinal motor neurons.

Dev Biol 2005 Jul;283(2):474-85

Department of Neurology and Neuroscience, Cornell University Medical Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.ydbio.2005.04.017DOI Listing
July 2005

Neurology and the stem cell debate.

Authors:
Steven A Goldman

Neurology 2005 May;64(10):1675-6

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http://dx.doi.org/10.1212/01.WNL.0000165312.12463.BEDOI Listing
May 2005

Directed mobilization of endogenous neural progenitor cells: the intersection of stem cell biology and gene therapy.

Authors:
Steven A Goldman

Curr Opin Mol Ther 2004 Oct;6(5):466-72

University of Rochester Medical Center, Division of Cell and Gene Therapy, Department of Neurology, Rochester, NY 14642, USA.

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October 2004

P2X7 receptor inhibition improves recovery after spinal cord injury.

Nat Med 2004 Aug 18;10(8):821-7. Epub 2004 Jul 18.

Department of Neurosurgery, Center for Aging and Developmental Biology, University of Rochester Medical Center, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1038/nm1082DOI Listing
August 2004

Telomerase immortalization of neuronally restricted progenitor cells derived from the human fetal spinal cord.

Nat Biotechnol 2004 Mar 15;22(3):297-305. Epub 2004 Feb 15.

Department of Neurology and Neuroscience, Cornell University Medical Center, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nbt944DOI Listing
March 2004

Fetal and adult human oligodendrocyte progenitor cell isolates myelinate the congenitally dysmyelinated brain.

Nat Med 2004 Jan 21;10(1):93-7. Epub 2003 Dec 21.

Department of Neurology and Neuroscience, Cornell University Medical College, 1300 York Ave., New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nm974DOI Listing
January 2004

New roles for astrocytes: redefining the functional architecture of the brain.

Trends Neurosci 2003 Oct;26(10):523-30

Department of Cell Biology, New York Medical College, Valhalla, NY 10595, USA.

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http://dx.doi.org/10.1016/j.tins.2003.08.008DOI Listing
October 2003

Nitric oxide negatively regulates mammalian adult neurogenesis.

Proc Natl Acad Sci U S A 2003 Aug 28;100(16):9566-71. Epub 2003 Jul 28.

Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

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http://dx.doi.org/10.1073/pnas.1633579100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC170958PMC
August 2003

Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain.

Nat Med 2003 Apr 10;9(4):439-47. Epub 2003 Mar 10.

Department of Neurology and Neuroscience, Cornell University Medical College, New York, New York, USA.

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http://dx.doi.org/10.1038/nm837DOI Listing
April 2003

Induced neurogenesis by endogenous progenitor cells in the adult mammalian brain.

Prog Brain Res 2002 ;138:451-64

Department of Neurology and Neuroscience, Cornell University Medical College, 1300 York Ave., Room E607, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/s0079-6123(02)38093-2DOI Listing
December 2002

Progenitor cells derived from the adult human subcortical white matter disperse and differentiate as oligodendrocytes within demyelinated lesions of the rat brain.

J Neurosci Res 2002 Sep;69(6):966-75

Department of Neurology and Neuroscience, Cornell University Medical College, New York, New York 10021, USA.

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http://dx.doi.org/10.1002/jnr.10397DOI Listing
September 2002

Erythropoietin strikes a new cord.

Nat Med 2002 Aug;8(8):785-7

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http://dx.doi.org/10.1038/nm0802-785DOI Listing
August 2002

Coordinated interaction of neurogenesis and angiogenesis in the adult songbird brain.

Neuron 2002 Jun;34(6):945-60

Department of Neurology and Neuroscience, Cornell University Medical Center, 1300 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/s0896-6273(02)00722-5DOI Listing
June 2002