Steve Oh

Steve Oh

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Steve Oh

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Human mesenchymal stem cell therapy for cartilage repair: Review on isolation, expansion, and constructs.

Stem Cell Res 2020 Feb 18;44:101738. Epub 2020 Feb 18.

Bioprocessing Technology Institute, A*STAR (Agency for Science, Technology and Research), Singapore 138668, Singapore.

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http://dx.doi.org/10.1016/j.scr.2020.101738DOI Listing
February 2020

Rapid Detection of Senescent Mesenchymal Stromal Cells by a Fluorescent Probe.

Biotechnol J 2019 Oct 15;14(10):e1800691. Epub 2019 Jul 15.

Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way #02-02 Helios, Singapore, 138667, Singapore.

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http://dx.doi.org/10.1002/biot.201800691DOI Listing
October 2019

High-throughput amplicon sequencing of the full-length 16S rRNA gene with single-nucleotide resolution.

Nucleic Acids Res 2019 10;47(18):e103

Department of Medicine, Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1093/nar/gkz569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765137PMC
October 2019

Sub-confluent culture of human mesenchymal stromal cells on biodegradable polycaprolactone microcarriers enhances bone healing of rat calvarial defect.

Cytotherapy 2019 06 8;21(6):631-642. Epub 2019 Apr 8.

Stem Cell Group 2 Bioprocessing Technology Institute, Agency of Science, Technology and Research (A*STAR), Singapore.

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http://dx.doi.org/10.1016/j.jcyt.2019.03.004DOI Listing
June 2019

Scaled-Up Inertial Microfluidics: Retention System for Microcarrier-Based Suspension Cultures.

Biotechnol J 2019 May 15;14(5):e1800674. Epub 2019 Apr 15.

Bio-Manufacturing Programme, Singapore Institute of Manufacturing Technology (SIMTech), Agency for Science, Technology and Research (A*STAR), Innovis, Singapore, 138634.

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http://doi.wiley.com/10.1002/biot.201800674
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http://dx.doi.org/10.1002/biot.201800674DOI Listing
May 2019

Review: In vitro generation of red blood cells for transfusion medicine: Progress, prospects and challenges.

Biotechnol Adv 2018 12 29;36(8):2118-2128. Epub 2018 Sep 29.

Stem Cell Group, Bioprocessing Technology Institute, Agency for Science, Technology and Research, Singapore 138668, Republic of Singapore.

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https://linkinghub.elsevier.com/retrieve/pii/S07349750183016
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http://dx.doi.org/10.1016/j.biotechadv.2018.09.006DOI Listing
December 2018

Influencing the Fate of Cardiac and Neural Stem Cell Differentiation Using Small Molecule Inhibitors of ALK5.

Stem Cells Transl Med 2018 10 31;7(10):709-720. Epub 2018 Jul 31.

Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore, 117543, Singapore.

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http://dx.doi.org/10.1002/sctm.17-0246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186272PMC
October 2018

Meticulous optimization of cardiomyocyte yields in a 3-stage continuous integrated agitation bioprocess.

Stem Cell Res 2018 08 1;31:161-173. Epub 2018 Aug 1.

Bioprocessing Technology Institute, A*STAR (Agency for Science, Technology and Research), Singapore 138668, Singapore.

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http://dx.doi.org/10.1016/j.scr.2018.07.020DOI Listing
August 2018

Inertial-Based Filtration Method for Removal of Microcarriers from Mesenchymal Stem Cell Suspensions.

Sci Rep 2018 08 20;8(1):12481. Epub 2018 Aug 20.

Bio-Manufacturing Programme, Singapore Institute of Manufacturing Technology (SIMTech), Agency for Science, Technology and Research (A*STAR), Innovis, Singapore, 138634, Singapore.

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http://dx.doi.org/10.1038/s41598-018-31019-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102204PMC
August 2018

Immobilization of vitronectin-binding heparan sulfates onto surfaces to support human pluripotent stem cells.

J Biomed Mater Res B Appl Biomater 2018 07 20;106(5):1887-1896. Epub 2017 Sep 20.

Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, #06-06 Immunos, Singapore, 138648, Singapore.

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http://dx.doi.org/10.1002/jbm.b.33999DOI Listing
July 2018

Unraveling the Inconsistencies of Cardiac Differentiation Efficiency Induced by the GSK3β Inhibitor CHIR99021 in Human Pluripotent Stem Cells.

Stem Cell Reports 2018 06 26;10(6):1851-1866. Epub 2018 Apr 26.

Bioprocessing Technology Institute, 20 Biopolis Way, Centros #06-01, Singapore 138668, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.03.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989659PMC
June 2018

Construction of a vascularized hydrogel for cardiac tissue formation in a porcine model.

J Tissue Eng Regen Med 2018 04 10;12(4):e2029-e2038. Epub 2018 Jan 10.

National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore.

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http://dx.doi.org/10.1002/term.2634DOI Listing
April 2018

Defined Serum-Free Medium for Bioreactor Culture of an Immortalized Human Erythroblast Cell Line.

Biotechnol J 2018 Apr 6;13(4):e1700567. Epub 2018 Feb 6.

Stem Cell Group, Bioprocessing Technology Institute, Agency for Science, Technology and Research, 20 Biopolis Way, Centros, Level 4, Singapore, 138668, Republic of Singapore.

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http://dx.doi.org/10.1002/biot.201700567DOI Listing
April 2018

The Diversity, Structure, and Function of Heritable Adaptive Immunity Sequences in the Aedes aegypti Genome.

Curr Biol 2017 Nov 9;27(22):3511-3519.e7. Epub 2017 Nov 9.

Department of Microbiology and Immunology, University of California, San Francisco, 600 16(th) Street, GH-S572, UCSF Box 2280, San Francisco, CA 94143-2280, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2017.09.067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698160PMC
November 2017

Erratum: Identification of Na/K-ATPase inhibition-independent proarrhythmic ionic mechanisms of cardiac glycosides.

Sci Rep 2017 09 13;7(1):11498. Epub 2017 Sep 13.

National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, 169609, Republic of Singapore.

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http://dx.doi.org/10.1038/s41598-017-09613-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597635PMC
September 2017

Critical attributes of human early mesenchymal stromal cell-laden microcarrier constructs for improved chondrogenic differentiation.

Stem Cell Res Ther 2017 05 8;8(1):93. Epub 2017 May 8.

Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01 Centros, Singapore, 138668, Singapore.

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http://dx.doi.org/10.1186/s13287-017-0538-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421335PMC
May 2017

Identification of Na+/K+-ATPase inhibition-independent proarrhythmic ionic mechanisms of cardiac glycosides.

Sci Rep 2017 05 26;7(1):2465. Epub 2017 May 26.

National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, 169609, Republic of Singapore.

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http://dx.doi.org/10.1038/s41598-017-02496-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446409PMC
May 2017

Microcarrier-Expanded Neural Progenitor Cells Can Survive, Differentiate, and Innervate Host Neurons Better When Transplanted as Aggregates.

Cell Transplant 2016 30;25(7):1343-57. Epub 2015 Dec 30.

Neural Stem Cell Research Lab, Research Department, National Neuroscience Institute, Singapore.

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http://dx.doi.org/10.3727/096368915X690378DOI Listing
March 2017

Biodegradable poly-ε-caprolactone microcarriers for efficient production of human mesenchymal stromal cells and secreted cytokines in batch and fed-batch bioreactors.

Cytotherapy 2017 03 22;19(3):419-432. Epub 2016 Dec 22.

Stem Cell Group, Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2016.11.009DOI Listing
March 2017

Tunable Volumetric Density and Porous Structure of Spherical Poly-ε-caprolactone Microcarriers, as Applied in Human Mesenchymal Stem Cell Expansion.

Langmuir 2017 03 16;33(12):3068-3079. Epub 2017 Mar 16.

Institute of Materials Research and Engineering, A*STAR (Agency for Science, Technology and Research) , 2 Fusionopolis Way, Innovis, #08-03, 138634, Singapore.

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http://dx.doi.org/10.1021/acs.langmuir.7b00125DOI Listing
March 2017

Biodegradable ECM-coated PCL microcarriers support scalable human early MSC expansion and in vivo bone formation.

Cytotherapy 2016 10 5;18(10):1332-44. Epub 2016 Aug 5.

Stem Cell Group, Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2016.06.016DOI Listing
October 2016

Managing particulates in cell therapy: Guidance for best practice.

Cytotherapy 2016 09 12;18(9):1063-76. Epub 2016 Jul 12.

International Society for Cellular Therapy Process and Product Development Subcommittee, USA; Stem Cell Group, Bioprocessing Technology Institute, Centros, Singapore.

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http://dx.doi.org/10.1016/j.jcyt.2016.05.011DOI Listing
September 2016

Superior Red Blood Cell Generation from Human Pluripotent Stem Cells Through a Novel Microcarrier-Based Embryoid Body Platform.

Tissue Eng Part C Methods 2016 08 1;22(8):765-80. Epub 2016 Aug 1.

1 Stem Cell Group, Bioprocessing Technology Institute , Agency for Science, Technology and Research, Singapore, Republic of Singapore .

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http://dx.doi.org/10.1089/ten.TEC.2015.0579DOI Listing
August 2016

Genome-Wide Transcriptome and Binding Sites Analyses Identify Early FOX Expressions for Enhancing Cardiomyogenesis Efficiency of hESC Cultures.

Sci Rep 2016 08 9;6:31068. Epub 2016 Aug 9.

Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01, Singapore 138668, Singapore.

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http://dx.doi.org/10.1038/srep31068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977469PMC
August 2016

'Candidatus Tenderia electrophaga', an uncultivated electroautotroph from a biocathode enrichment.

Int J Syst Evol Microbiol 2016 Jun 7;66(6):2178-2185. Epub 2016 Mar 7.

United States Naval Research Laboratory, 4555 Overlook Ave SW, Washington, DC 20375, USA.

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http://dx.doi.org/10.1099/ijsem.0.001006DOI Listing
June 2016

Expansion in microcarrier-spinner cultures improves the chondrogenic potential of human early mesenchymal stromal cells.

Cytotherapy 2016 06;18(6):740-53

Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14653249163032
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http://dx.doi.org/10.1016/j.jcyt.2016.03.293DOI Listing
June 2016

Integrated processes for expansion and differentiation of human pluripotent stem cells in suspended microcarriers cultures.

Biochem Biophys Res Commun 2016 05 15;473(3):764-8. Epub 2015 Sep 15.

Stem Cell Group, Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X153059
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http://dx.doi.org/10.1016/j.bbrc.2015.09.079DOI Listing
May 2016

Recent advances in serum-free microcarrier expansion of mesenchymal stromal cells: Parameters to be optimized.

Biochem Biophys Res Commun 2016 05 15;473(3):769-73. Epub 2015 Sep 15.

Stem Cell Group, Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01 Centros, Singapore 138668, Singapore. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X153059
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http://dx.doi.org/10.1016/j.bbrc.2015.09.078DOI Listing
May 2016

Fabrication of uniform-sized poly-ɛ-caprolactone microspheres and their applications in human embryonic stem cell culture.

Biomed Microdevices 2015 Dec;17(6):105

A*STAR (Agency for Science, Technology and Research), Institute of Materials Research and Engineering, 2 Fusionopolis Way, Innovis, #08-03, Singapore, 138634, Singapore.

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http://dx.doi.org/10.1007/s10544-015-0010-6DOI Listing
December 2015

Concise Review: Process Development Considerations for Cell Therapy.

Stem Cells Transl Med 2015 Oct 27;4(10):1155-63. Epub 2015 Aug 27.

International Society for Cellular Therapy Process and Product Development Subcommittee, Vancouver, British Columbia, Canada; Thermo Fisher Scientific, Inc., Grand Island, New York, USA; Celgene Cellular Therapeutics, Warren, New Jersey, USA; Pluristem Therapeutics Inc., Haifa, Israel; Rooster Bio Inc., Frederick, Maryland, USA; Novartis Pharmaceuticals, Morris Plains, New Jersey, USA; Pall Life Sciences (division of Pall Corp), Port Washington, New York, USA; Stem Cell Group, Bioprocessing Technology Institute, A*STAR, Singapore, Singapore.

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http://dx.doi.org/10.5966/sctm.2014-0294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572896PMC
October 2015

Enhanced in vitro osteogenic differentiation of human fetal MSCs attached to 3D microcarriers versus harvested from 2D monolayers.

BMC Biotechnol 2015 Oct 31;15:102. Epub 2015 Oct 31.

Stem Cell Group, Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01 Centros, Singapore, 138668, Singapore.

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http://dx.doi.org/10.1186/s12896-015-0219-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628389PMC
October 2015

Serum-free media formulations are cell line-specific and require optimization for microcarrier culture.

Cytotherapy 2015 Aug;17(8):1152-65

Stem Cell Group, Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Centros, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2015.05.001DOI Listing
August 2015

Improved Human Pluripotent Stem Cell Attachment and Spreading on Xeno-Free Laminin-521-Coated Microcarriers Results in Efficient Growth in Agitated Cultures.

Biores Open Access 2015 1;4(1):242-57. Epub 2015 Apr 1.

Stem Cell Group, Bioprocessing Technology Institute , Agency for Science, Technology and Research (ASTAR), Singapore , Singapore.

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http://www.liebertpub.com/doi/10.1089/biores.2015.0010
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http://dx.doi.org/10.1089/biores.2015.0010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540119PMC
August 2015

Pushing the envelope in tissue engineering: ex vivo production of thick vascularized cardiac extracellular matrix constructs.

Tissue Eng Part A 2015 May 19;21(9-10):1507-19. Epub 2015 Mar 19.

1 The Laboratory of Cancer Drug Delivery & Mammalian Cell Technology, Faculty of Biotechnology and Food Engineering, Technion-Israel Institute of Technology , Haifa, Israel .

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http://dx.doi.org/10.1089/ten.tea.2014.0477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426298PMC
May 2015

Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling.

J Mol Cell Cardiol 2015 Mar 19;80:56-70. Epub 2014 Dec 19.

Bioprocessing Technology Institute, 20 Biopolis Way, Centros #06-01, Singapore 138668, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2014.12.003DOI Listing
March 2015

Enabling consistency in pluripotent stem cell-derived products for research and development and clinical applications through material standards.

Stem Cells Transl Med 2015 Mar 3;4(3):217-23. Epub 2015 Feb 3.

Oxford-UCL Centre for the Advancement of Sustainable Medical Innovation and Harvard Stem Cell Institute, Cambridge, Massachusetts; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts, USA; Saïd Business School, University of Oxford, Oxford, United Kingdom; Centre for Behavioural Medicine, UCL School of Pharmacy, University College London, London, United Kingdom; Stanford-UCSF FDA Center of Excellence in Regulatory Science and Innovation (CERSI), San Francisco, California, USA

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http://dx.doi.org/10.5966/sctm.2014-0233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339854PMC
March 2015

An intermittent rocking platform for integrated expansion and differentiation of human pluripotent stem cells to cardiomyocytes in suspended microcarrier cultures.

Stem Cell Res 2014 Sep 27;13(2):202-13. Epub 2014 Jun 27.

Bioprocessing Technology Institute, A*STAR (Agency for Science, Technology and Research), Singapore 138668, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2014.06.002DOI Listing
September 2014

Time-resolved video analysis and management system for monitoring cardiomyocyte differentiation processes and toxicology assays.

Biotechnol J 2014 May 16;9(5):675-83. Epub 2014 Apr 16.

Bioprocessing Technology Institute, A*STAR (Agency for Science, Technology and Research), Singapore.

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http://dx.doi.org/10.1002/biot.201300262DOI Listing
May 2014

Inhibition of ROCK-myosin II signaling pathway enables culturing of human pluripotent stem cells on microcarriers without extracellular matrix coating.

Tissue Eng Part C Methods 2014 Mar 25;20(3):227-38. Epub 2013 Jul 25.

Stem Cell Group, Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR) , Singapore, Singapore .

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http://dx.doi.org/10.1089/ten.TEC.2013.0191DOI Listing
March 2014

Electrical stimulation promotes maturation of cardiomyocytes derived from human embryonic stem cells.

J Cardiovasc Transl Res 2013 Dec 1;6(6):989-99. Epub 2013 Oct 1.

Cardiology Division, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1007/s12265-013-9510-zDOI Listing
December 2013

High-throughput fingerprinting of human pluripotent stem cell fate responses and lineage bias.

Nat Methods 2013 Dec 20;10(12):1225-31. Epub 2013 Oct 20.

Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061564PMC
http://dx.doi.org/10.1038/nmeth.2684DOI Listing
December 2013

Application of human mesenchymal and pluripotent stem cell microcarrier cultures in cellular therapy: achievements and future direction.

Biotechnol Adv 2013 Nov 24;31(7):1032-46. Epub 2013 Mar 24.

Bioprocessing Technology Institute, A*STAR (Agency for Science, Technology and Research), 20 Biopolis Way, #06-01, 138668, Singapore. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07349750130006
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http://dx.doi.org/10.1016/j.biotechadv.2013.03.006DOI Listing
November 2013

A physical sciences network characterization of non-tumorigenic and metastatic cells.

Authors:
David B Agus Jenolyn F Alexander Wadih Arap Shashanka Ashili Joseph E Aslan Robert H Austin Vadim Backman Kelly J Bethel Richard Bonneau Wei-Chiang Chen Chira Chen-Tanyolac Nathan C Choi Steven A Curley Matthew Dallas Dhwanil Damania Paul C W Davies Paolo Decuzzi Laura Dickinson Luis Estevez-Salmeron Veronica Estrella Mauro Ferrari Claudia Fischbach Jasmine Foo Stephanie I Fraley Christian Frantz Alexander Fuhrmann Philippe Gascard Robert A Gatenby Yue Geng Sharon Gerecht Robert J Gillies Biana Godin William M Grady Alex Greenfield Courtney Hemphill Barbara L Hempstead Abigail Hielscher W Daniel Hillis Eric C Holland Arig Ibrahim-Hashim Tyler Jacks Roger H Johnson Ahyoung Joo Jonathan E Katz Laimonas Kelbauskas Carl Kesselman Michael R King Konstantinos Konstantopoulos Casey M Kraning-Rush Peter Kuhn Kevin Kung Brian Kwee Johnathon N Lakins Guillaume Lambert David Liao Jonathan D Licht Jan T Liphardt Liyu Liu Mark C Lloyd Anna Lyubimova Parag Mallick John Marko Owen J T McCarty Deirdre R Meldrum Franziska Michor Shannon M Mumenthaler Vivek Nandakumar Thomas V O'Halloran Steve Oh Renata Pasqualini Matthew J Paszek Kevin G Philips Christopher S Poultney Kuldeepsinh Rana Cynthia A Reinhart-King Robert Ros Gregg L Semenza Patti Senechal Michael L Shuler Srimeenakshi Srinivasan Jack R Staunton Yolanda Stypula Hariharan Subramanian Thea D Tlsty Garth W Tormoen Yiider Tseng Alexander van Oudenaarden Scott S Verbridge Jenny C Wan Valerie M Weaver Jonathan Widom Christine Will Denis Wirtz Jonathan Wojtkowiak Pei-Hsun Wu

Sci Rep 2013 ;3:1449

Center for Applied Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1038/srep01449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636513PMC
October 2013

Nutrient supplemented serum-free medium increases cardiomyogenesis efficiency of human pluripotent stem cells.

World J Stem Cells 2013 Jul;5(3):86-97

Sherwin Ting, Marti Lecina, Shaul Reuveny, Steve KW Oh, Bioprocessing Technology Institute, ASTAR (Agency for Science, Technology and Research), Singapore 138668, Singapore.

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http://dx.doi.org/10.4252/wjsc.v5.i3.86DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723792PMC
July 2013

Tri-substituted imidazole analogues of SB203580 as inducers for cardiomyogenesis of human embryonic stem cells.

Bioorg Med Chem Lett 2013 Jun 4;23(11):3300-3. Epub 2013 Apr 4.

Institute of Chemical and Engineering Sciences, 8 Biomedical Grove, Neuros #07-01, Singapore 138665, Singapore.

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http://dx.doi.org/10.1016/j.bmcl.2013.03.103DOI Listing
June 2013

Microcarrier suspension cultures for high-density expansion and differentiation of human pluripotent stem cells to neural progenitor cells.

Tissue Eng Part C Methods 2013 Feb 4;19(2):166-80. Epub 2012 Sep 4.

Bioprocessing Technology Institute, A*STAR-Agency for Science, Technology and Research, Singapore, Singapore.

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http://dx.doi.org/10.1089/ten.TEC.2012.0146DOI Listing
February 2013

Managing particulates in cellular therapy.

Cytotherapy 2012 Oct 17;14(9):1032-40. Epub 2012 Aug 17.

International Society for Cellular Therapy Process and Product Development Subcommittee, NC, USA.

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http://dx.doi.org/10.3109/14653249.2012.706709DOI Listing
October 2012

The Promise and Therapeutic Potential of Human ES and iPS Cells.

Stem Cells Int 2011 18;2011:959275. Epub 2011 Dec 18.

Advanced Cell Technology, Marlborough, MA 01752, USA.

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http://dx.doi.org/10.4061/2011/959275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246778PMC
August 2012

Translating human embryonic stem cells from 2-dimensional to 3-dimensional cultures in a defined medium on laminin- and vitronectin-coated surfaces.

Stem Cells Dev 2012 Jul 23;21(10):1701-15. Epub 2011 Dec 23.

Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.

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http://dx.doi.org/10.1089/scd.2011.0509DOI Listing
July 2012

Differentiation of human embryonic stem cells to cardiomyocytes on microcarrier cultures.

Curr Protoc Stem Cell Biol 2012 May;Chapter 1:Unit1D.7

Bioprocessing Technology Institute, A*STAR-Agency for Science, Technology and Research, Singapore.

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http://dx.doi.org/10.1002/9780470151808.sc01d07s21DOI Listing
May 2012

Activated T cells modulate immunosuppression by embryonic-and bone marrow-derived mesenchymal stromal cells through a feedback mechanism.

Cytotherapy 2012 Mar 5;14(3):274-84. Epub 2011 Dec 5.

Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore.

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http://dx.doi.org/10.3109/14653249.2011.635853DOI Listing
March 2012

Distinct regulation of mitogen-activated protein kinase activities is coupled with enhanced cardiac differentiation of human embryonic stem cells.

Stem Cell Res 2011 Nov 23;7(3):198-209. Epub 2011 Jul 23.

Bioprocessing Technology Institute, A*STAR (Agency for Science, Technology and Research), 20 Biopolis Way, #06-01, 138668 Singapore.

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http://dx.doi.org/10.1016/j.scr.2011.06.001DOI Listing
November 2011

Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage.

Authors:
Katherine Amps Peter W Andrews George Anyfantis Lyle Armstrong Stuart Avery Hossein Baharvand Julie Baker Duncan Baker Maria B Munoz Stephen Beil Nissim Benvenisty Dalit Ben-Yosef Juan-Carlos Biancotti Alexis Bosman Romulo Martin Brena Daniel Brison Gunilla Caisander María V Camarasa Jieming Chen Eric Chiao Young Min Choi Andre B H Choo Daniel Collins Alan Colman Jeremy M Crook George Q Daley Anne Dalton Paul A De Sousa Chris Denning Janet Downie Petr Dvorak Karen D Montgomery Anis Feki Angela Ford Victoria Fox Ana M Fraga Tzvia Frumkin Lin Ge Paul J Gokhale Tamar Golan-Lev Hamid Gourabi Michal Gropp Guangxiu Lu Ales Hampl Katie Harron Lyn Healy Wishva Herath Frida Holm Outi Hovatta Johan Hyllner Maneesha S Inamdar Astrid Kresentia Irwanto Tetsuya Ishii Marisa Jaconi Ying Jin Susan Kimber Sergey Kiselev Barbara B Knowles Oded Kopper Valeri Kukharenko Anver Kuliev Maria A Lagarkova Peter W Laird Majlinda Lako Andrew L Laslett Neta Lavon Dong Ryul Lee Jeoung Eun Lee Chunliang Li Linda S Lim Tenneille E Ludwig Yu Ma Edna Maltby Ileana Mateizel Yoav Mayshar Maria Mileikovsky Stephen L Minger Takamichi Miyazaki Shin Yong Moon Harry Moore Christine Mummery Andras Nagy Norio Nakatsuji Kavita Narwani Steve K W Oh Sun Kyung Oh Cia Olson Timo Otonkoski Fei Pan In-Hyun Park Steve Pells Martin F Pera Lygia V Pereira Ouyang Qi Grace Selva Raj Benjamin Reubinoff Alan Robins Paul Robson Janet Rossant Ghasem H Salekdeh Thomas C Schulz Karen Sermon Jameelah Sheik Mohamed Hui Shen Eric Sherrer Kuldip Sidhu Shirani Sivarajah Heli Skottman Claudia Spits Glyn N Stacey Raimund Strehl Nick Strelchenko Hirofumi Suemori Bowen Sun Riitta Suuronen Kazutoshi Takahashi Timo Tuuri Parvathy Venu Yuri Verlinsky Dorien Ward-van Oostwaard Daniel J Weisenberger Yue Wu Shinya Yamanaka Lorraine Young Qi Zhou

Nat Biotechnol 2011 Nov 27;29(12):1132-44. Epub 2011 Nov 27.

Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454460PMC
November 2011

Critical microcarrier properties affecting the expansion of undifferentiated human embryonic stem cells.

Stem Cell Res 2011 Sep 11;7(2):97-111. Epub 2011 May 11.

Stem Cell Group, Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore.

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http://dx.doi.org/10.1016/j.scr.2011.04.007DOI Listing
September 2011

Agitation can induce differentiation of human pluripotent stem cells in microcarrier cultures.

Tissue Eng Part C Methods 2011 Feb 4;17(2):165-72. Epub 2010 Nov 4.

Bioprocessing Technology Institute , A*STAR (Agency for Science, Technology and Research), Singapore, Singapore.

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http://dx.doi.org/10.1089/ten.TEC.2010.0320DOI Listing
February 2011

Defining a threshold surface density of vitronectin for the stable expansion of human embryonic stem cells.

Tissue Eng Part C Methods 2011 Feb 7;17(2):193-207. Epub 2010 Oct 7.

Stem Cells and Tissue Repair Group, Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.

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http://dx.doi.org/10.1089/ten.TEC.2010.0328DOI Listing
February 2011

Scalable platform for human embryonic stem cell differentiation to cardiomyocytes in suspended microcarrier cultures.

Tissue Eng Part C Methods 2010 Dec 28;16(6):1609-19. Epub 2010 Aug 28.

Bioprocessing Technology Institute, A*STAR (Agency for Science, Technology and Research), Singapore, Singapore.

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http://dx.doi.org/10.1089/ten.TEC.2010.0104DOI Listing
December 2010

Establishing efficient siRNA knockdown in stem cells using fluorescent oligonucleotides.

Methods Mol Biol 2010 ;650:75-83

Stem Cell Group, Bioprocessing Technology Institute, Centros, Singapore.

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December 2010

Investigations into the metabolism of two-dimensional colony and suspended microcarrier cultures of human embryonic stem cells in serum-free media.

Stem Cells Dev 2010 Nov 10;19(11):1781-92. Epub 2010 Sep 10.

Bioprocessing Technology Institute, A*STAR (Agency for Science, Technology and Research), Singapore, Singapore.

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http://dx.doi.org/10.1089/scd.2010.0077DOI Listing
November 2010

Expansion of human embryonic stem cells on cellulose microcarriers.

Curr Protoc Stem Cell Biol 2010 Sep;Chapter 1:Unit 1C.11

Stem Cell Group, Bioprocessing Technology Institute, A*STAR (Agency for Science, Technology and Research), Centros, Singapore.

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http://dx.doi.org/10.1002/9780470151808.sc01c11s14DOI Listing
September 2010

Impact of vitronectin concentration and surface properties on the stable propagation of human embryonic stem cells.

Biointerphases 2010 Sep;5(3):FA132-42

Institute of Materials Research and Engineering, Agency for Science, Technology and Research (A*STAR), Singapore 117602.

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http://dx.doi.org/10.1116/1.3525804DOI Listing
September 2010

Population estimation of human embryonic stem cell cultures.

Biotechnol Prog 2010 Mar-Apr;26(2):573-9

Stem Cell Group, Bioprocessing Technology Institute, Biomedical Sciences Institutes, A*STAR, Singapore.

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http://dx.doi.org/10.1002/btpr.344DOI Listing
July 2010

Defined and serum-free media support undifferentiated human embryonic stem cell growth.

Stem Cells Dev 2010 Jun;19(6):753-61

Bioprocessing Technology Institute, A*STAR (Agency for Science, Technology and Research), Centros, Singapore.

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http://dx.doi.org/10.1089/scd.2009.0210DOI Listing
June 2010

Human ES cell lines--introduction.

In Vitro Cell Dev Biol Anim 2010 Apr 7;46(3-4):167-8. Epub 2010 Mar 7.

Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield S10 2TN, UK.

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http://dx.doi.org/10.1007/s11626-010-9306-2DOI Listing
April 2010

Double Holliday junctions are intermediates of DNA break repair.

Nature 2010 Apr 28;464(7290):937-41. Epub 2010 Mar 28.

Department of Microbiology, University of California Davis, Davis, California 95616, USA.

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http://dx.doi.org/10.1038/nature08868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851831PMC
April 2010

KLF4 and PBX1 directly regulate NANOG expression in human embryonic stem cells.

Stem Cells 2009 Sep;27(9):2114-25

Stem Cell Group, Bioprocessing Technology Institute, A*STAR (Agency for Science, Technology and Research), Biopolis, Singapore.

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September 2009

Quantitative identification of teratoma tissues formed by human embryonic stem cells with TeratomEye.

Biotechnol Lett 2009 May 25;31(5):653-8. Epub 2009 Jan 25.

Stem Cell Group, Bioprocessing Technology Institute, A*STAR, 20 Biopolis Way #06 - 01 Centros, Singapore, 138668, Singapore.

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http://dx.doi.org/10.1007/s10529-009-9928-1DOI Listing
May 2009

Long-term microcarrier suspension cultures of human embryonic stem cells.

Stem Cell Res 2009 May 4;2(3):219-30. Epub 2009 Mar 4.

Stem Cell Group, Bioprocessing Technology Institute, A*STAR (Agency for Science, Technology, and Research), 20 Biopolis Way, No. 06-01 Centros, Singapore 138668, Singapore.

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http://dx.doi.org/10.1016/j.scr.2009.02.005DOI Listing
May 2009

Identification of cellular objective for elucidating the physiological state of plasmid-bearing Escherichia coli using genome-scale in silico analysis.

Biotechnol Prog 2009 Jan-Feb;25(1):61-7

Bioprocessing Technology Institute, A*STAR (Agency for Science, Technology and Research), Biopolis, Singapore 138668.

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http://doi.wiley.com/10.1002/btpr.51
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April 2009

Synthesis and anti-cancer activity of covalent conjugates of artemisinin and a transferrin-receptor targeting peptide.

Cancer Lett 2009 Feb 5;274(1):33-9. Epub 2008 Oct 5.

Department of Chemistry, University of Washington, Box 351700, Seattle, WA 98195-1700, USA.

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February 2009

Characterizing Escherichia coli DH5alpha growth and metabolism in a complex medium using genome-scale flux analysis.

Biotechnol Bioeng 2009 Feb;102(3):923-34

Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117576, Singapore.

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February 2009

Enhancement of plasmid DNA yields during fed-batch culture of a fruR-knockout Escherichia coli strain.

Biotechnol Appl Biochem 2009 Jan;52(Pt 1):53-9

Bioprocessing Technology Institute, 20 Biopolis Way, 06-01 Centros, Singapore. dave

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http://dx.doi.org/10.1042/BA20070260DOI Listing
January 2009

RecQ helicase, Sgs1, and XPF family endonuclease, Mus81-Mms4, resolve aberrant joint molecules during meiotic recombination.

Mol Cell 2008 Aug;31(3):324-36

Department of Microbiology, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA.

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http://dx.doi.org/10.1016/j.molcel.2008.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587322PMC
August 2008

Generation of high-level stable transgene expressing human embryonic stem cell lines using Chinese hamster elongation factor-1 alpha promoter system.

Stem Cells Dev 2008 Aug;17(4):825-36

Stem Cell Group, Agency for Science, Technology and Research (A*STAR), Biopolis Way, Centros, Singapore.

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http://dx.doi.org/10.1089/scd.2007.0233DOI Listing
August 2008

Autogeneic feeders for the culture of undifferentiated human embryonic stem cells in feeder and feeder-free conditions.

Methods Cell Biol 2008 ;86:15-28

Stem Cell Group, Bioprocessing Technology Institute, Agency for Science Technology and Research, Singapore 138668.

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July 2008

Selection against undifferentiated human embryonic stem cells by a cytotoxic antibody recognizing podocalyxin-like protein-1.

Stem Cells 2008 Jun 20;26(6):1454-63. Epub 2008 Mar 20.

Stem Cell Group, Bioprocessing Technology Institute, 20 Biopolis Way #06-01, Singapore.

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June 2008

Crossover assurance and crossover interference are distinctly regulated by the ZMM proteins during yeast meiosis.

Nat Genet 2008 Mar 24;40(3):299-309. Epub 2008 Feb 24.

Institute for Protein Research, Osaka University, Suita 565-0871, Japan.

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March 2008

The time is right: proteome biology of stem cells.

Cell Stem Cell 2008 Mar;2(3):215-7

Stem Cell and Leukemia Proteomics Laboratory, Faculty of Medical and Human Sciences, University of Manchester, Christie Hospital, Manchester M20 9BX, UK.

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http://dx.doi.org/10.1016/j.stem.2008.02.003DOI Listing
March 2008

Rad52 promotes postinvasion steps of meiotic double-strand-break repair.

Mol Cell 2008 Feb;29(4):517-24

Section of Microbiology, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA.

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http://dx.doi.org/10.1016/j.molcel.2007.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2351957PMC
February 2008

Human embryonic stem cell technology: large scale cell amplification and differentiation.

Cytotechnology 2006 Mar 23;50(1-3):181-90. Epub 2006 Jun 23.

Stem Cell Group, Bioprocessing Technology Institute, 20 Biopolis Way, #06 - 01 Centros, 138668, Singapore, Singapore,

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