Steve M Gentleman

Steve M Gentleman

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Steve M Gentleman

Steve M Gentleman

Publications by authors named "Steve M Gentleman"

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Hippocampal CA2 Lewy pathology is associated with cholinergic degeneration in Parkinson's disease with cognitive decline.

Acta Neuropathol Commun 2019 Apr 25;7(1):61. Epub 2019 Apr 25.

Neuropathology Unit, Division of Brain Sciences, Department of Medicine, Imperial College London, 4/F, Burlington Danes Building, Du Cane Road, London, W12 0NN, UK.

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http://dx.doi.org/10.1186/s40478-019-0717-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485180PMC
April 2019

The aftermath of boxing revisited: identifying chronic traumatic encephalopathy pathology in the original Corsellis boxer series.

Acta Neuropathol 2018 12 30;136(6):973-974. Epub 2018 Oct 30.

Division of Brain Sciences, Department of Medicine, Imperial College London, 4th Floor Burlington Danes Building, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK.

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http://dx.doi.org/10.1007/s00401-018-1926-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280830PMC
December 2018

TauBI or not TauBI: what was the question?

Brain 2018 09;141(9):2536-2539

Division of Brain Sciences, Imperial College London, London, UK.

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http://fdslive.oup.com/www.oup.com/pdf/production_in_progres
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http://dx.doi.org/10.1093/brain/awy225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113641PMC
September 2018

Author Correction: Next generation histology methods for three-dimensional imaging of fresh and archival human brain tissues.

Nat Commun 2018 07 10;9(1):2726. Epub 2018 Jul 10.

Neuropathology Unit, Division of Brain Sciences, Imperial College London, Burlington Danes Building, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK.

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http://www.nature.com/articles/s41467-018-05089-5
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http://dx.doi.org/10.1038/s41467-018-05089-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039484PMC
July 2018

Next generation histology methods for three-dimensional imaging of fresh and archival human brain tissues.

Nat Commun 2018 03 14;9(1):1066. Epub 2018 Mar 14.

Neuropathology Unit, Division of Brain Sciences, Imperial College London, Burlington Danes Building, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK.

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http://www.nature.com/articles/s41467-018-03359-w
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http://dx.doi.org/10.1038/s41467-018-03359-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852003PMC
March 2018

MSA prions exhibit remarkable stability and resistance to inactivation.

Acta Neuropathol 2018 01 28;135(1):49-63. Epub 2017 Aug 28.

Institute for Neurodegenerative Diseases, Weill Institute for Neurosciences, University of California, 675 Nelson Rising Lane, San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.1007/s00401-017-1762-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756500PMC
January 2018

Chemical Probes for Visualizing Intact Animal and Human Brain Tissue.

Cell Chem Biol 2017 Jun;24(6):659-672

School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China; State Key Laboratory of Brain and Cognitive Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China; Research Center of Reproduction, Development and Growth, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China; Joint Laboratory of Jinan University and The University of Hong Kong, GHM Institute of CNS Regeneration, Jinan University, Guangzhou 510632, China. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2017.05.015DOI Listing
June 2017

Microglial Activation in Traumatic Brain Injury.

Front Aging Neurosci 2017 28;9:208. Epub 2017 Jun 28.

Division of Brain Sciences, Department of Medicine, Imperial College LondonLondon, United Kingdom.

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http://dx.doi.org/10.3389/fnagi.2017.00208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487478PMC
June 2017

The anti-inflammatory Annexin A1 induces the clearance and degradation of the amyloid-β peptide.

J Neuroinflammation 2016 09 2;13(1):234. Epub 2016 Sep 2.

Division of Brain Sciences, Hammersmith Hospital, Imperial College London, London, W12 0NN, UK.

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http://dx.doi.org/10.1186/s12974-016-0692-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010757PMC
September 2016

ARTAG in the basal forebrain: widening the constellation of astrocytic tau pathology.

Acta Neuropathol Commun 2016 06 13;4(1):59. Epub 2016 Jun 13.

Neuropathology Unit, Division of Brain Sciences, Department of Medicine, Imperial College London, Burlington Danes Building, Hammersmith Hospital Campus, London, W12 0NN, UK.

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http://dx.doi.org/10.1186/s40478-016-0330-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906820PMC
June 2016

Amyloid pathology and axonal injury after brain trauma.

Neurology 2016 Mar 3;86(9):821-8. Epub 2016 Feb 3.

From the Division of Brain Sciences (G.S., A.F.R., P.E., P.H., J.C., R.L., S.M.G., R.A.H., P.M.M., D.J.B., D.J.S.), Department of Medicine, Imperial College London; Institute of Psychiatry, Psychology & Neuroscience (P.H., M.V., F.E.T.), King's College London; Institute of Neurology (R.J.G.), University College London, UK; MedTech West at Sahlgrenska University Hospital (R.A.H.), University of Gothenburg, Sweden; and Institute of Clinical Medicine (D.J.B.), Aarhus University, Denmark.

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http://dx.doi.org/10.1212/WNL.0000000000002413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793784PMC
March 2016

Differential expression of galanin in the cholinergic basal forebrain of patients with Lewy body disorders.

Acta Neuropathol Commun 2015 Dec 1;3:77. Epub 2015 Dec 1.

Division of Brain Sciences, Department of Medicine, Imperial College London, Burlington Danes Building, Hammersmith Hospital Campus, London, W12 0NN, UK.

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http://dx.doi.org/10.1186/s40478-015-0249-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666186PMC
December 2015

Celastrol enhances cell viability and inhibits amyloid-β production induced by lipopolysaccharide in vitro.

J Alzheimers Dis 2014 ;41(3):835-44

Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Chelsea & Westminster Hospital, London, UK.

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http://dx.doi.org/10.3233/JAD-131799DOI Listing
September 2015

Altered Expression of Brain Proteinase-Activated Receptor-2, Trypsin-2 and Serpin Proteinase Inhibitors in Parkinson's Disease.

J Mol Neurosci 2015 Sep 17;57(1):48-62. Epub 2015 May 17.

Centre for Neuroinflammation and Neurodegeneration, Division of Brain Sciences, Department of Medicine, Imperial College London, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK,

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http://dx.doi.org/10.1007/s12031-015-0576-8DOI Listing
September 2015

Propagation of prions causing synucleinopathies in cultured cells.

Proc Natl Acad Sci U S A 2015 Sep 18;112(35):E4949-58. Epub 2015 Aug 18.

Institute for Neurodegenerative Diseases, University of California, San Francisco, CA 94143; Department of Neurology, University of California, San Francisco, CA 94143; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143

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http://dx.doi.org/10.1073/pnas.1513426112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568231PMC
September 2015

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism.

Proc Natl Acad Sci U S A 2015 Sep 31;112(38):E5308-17. Epub 2015 Aug 31.

Institute for Neurodegenerative Diseases, University of California, San Francisco, CA 94143; Department of Neurology, University of California, San Francisco, CA 94143;

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http://dx.doi.org/10.1073/pnas.1514475112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586853PMC
September 2015

Nucleus basalis of Meynert revisited: anatomy, history and differential involvement in Alzheimer's and Parkinson's disease.

Acta Neuropathol 2015 Apr 30;129(4):527-40. Epub 2015 Jan 30.

Neuropathology Unit, Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK,

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http://dx.doi.org/10.1007/s00401-015-1392-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366544PMC
April 2015

Calcium CaV1 channel subtype mRNA expression in Parkinson's disease examined by in situ hybridization.

J Mol Neurosci 2015 Mar 31;55(3):715-24. Epub 2014 Aug 31.

Centre for Neuroinflammation and Neurodegeneration, Division of Brain Sciences, Department of Medicine, Imperial College London, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK,

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http://dx.doi.org/10.1007/s12031-014-0410-8DOI Listing
March 2015

Prenatal high-fat diet alters the cerebrovasculature and clearance of β-amyloid in adult offspring.

J Pathol 2015 Mar 7;235(4):619-31. Epub 2015 Jan 7.

Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, UK.

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http://dx.doi.org/10.1002/path.4468DOI Listing
March 2015

LRRK2 exonic variants and risk of multiple system atrophy.

Neurology 2014 Dec 5;83(24):2256-61. Epub 2014 Nov 5.

From the Section of Biostatistics (M.G.H., N.N.D.) and Departments of Neuroscience (A.I.S.-O., S.R., K.O., M.E.M., D.W.D., O.A.R.) and Neurology (S.F., W.P.C., R.J.U., Z.K.W.), Mayo Clinic, Jacksonville, FL; Department of Molecular Neuroscience (L.S., A.S., H.H.), Institute of Neurology and The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK; Department of Medical Genetics (M.J.F.), University of British Columbia, Vancouver, Canada; Laboratory of Neurogenetics (A.B.S.), National Institute on Aging, Bethesda, MD; Institute of Genetic Medicine (P.F.C., M.J.K.), Newcastle University, Central Parkway, Newcastle upon Tyne; Neuropathology Unit (S.M.G.), Department of Medicine, Imperial College London; Queen Square Brain Bank for Neurological Disorders (J.L.H., K.A.), Department of Molecular Neuroscience, UCL Institute of Neurology, University College London; Clinical and Cognitive Sciences Research Group (D.M.A.M.), Institute of Brain, Behavior and Mental Health, Faculty of Medical and Human Sciences, University of Manchester, Salford Royal Hospital, Salford; and MRC London Neurodegenerative Diseases Brain Bank (S.A.-S., C.T.), King's College London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000001078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277668PMC
December 2014

Phenotypic profile of alternative activation marker CD163 is different in Alzheimer's and Parkinson's disease.

Acta Neuropathol Commun 2014 Feb 14;2:21. Epub 2014 Feb 14.

Neuropathology Unit, Division of Brain Sciences, Department of Medicine, Imperial College London, Charing Cross Campus, St Dunstan's Road, London, UK.

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http://dx.doi.org/10.1186/2051-5960-2-21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940003PMC
February 2014

Transmission of multiple system atrophy prions to transgenic mice.

Proc Natl Acad Sci U S A 2013 Nov 11;110(48):19555-60. Epub 2013 Nov 11.

Institute for Neurodegenerative Diseases, and Departments of Neurology and Pathology, University of California, San Francisco, CA 94143.

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http://dx.doi.org/10.1073/pnas.1318268110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845125PMC
November 2013

Parkinson's disease is associated with altered expression of CaV1 channels and calcium-binding proteins.

Brain 2013 Jul 14;136(Pt 7):2077-97. Epub 2013 Jun 14.

Centre for Neuroinflammation and Neurodegeneration, Division of Brain Sciences, Imperial College, London, W12 0NN, UK.

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http://dx.doi.org/10.1093/brain/awt134DOI Listing
July 2013

Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis.

Brain 2011 Sep 11;134(Pt 9):2755-71. Epub 2011 Aug 11.

Centre for Neuroscience, Division of Experimental Medicine, Imperial College Faculty of Medicine, Hammersmith Hospital Campus, Burlington Danes Building, Du Cane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1093/brain/awr182DOI Listing
September 2011

NSAIDs: How they Work and their Prospects as Therapeutics in Alzheimer's Disease.

Front Aging Neurosci 2010 18;2:20. Epub 2010 May 18.

Centre for Neuroscience, Division of Experimental Medicine, Imperial College London London, UK.

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http://dx.doi.org/10.3389/fnagi.2010.00020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893374PMC
July 2011

Interactions between APP secretases and inflammatory mediators.

J Neuroinflammation 2008 Jun 18;5:25. Epub 2008 Jun 18.

Division of Neuroscience and Mental Health, Imperial College London, The Hammersmith Hospital, Du cane Road, London W12 0NN, UK.

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http://jneuroinflammation.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/1742-2094-5-25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442055PMC
June 2008