Steve Lefever

Steve Lefever

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Steve Lefever

Steve Lefever

Publications by authors named "Steve Lefever"

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39Publications

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Antisense Oligonucleotide-Based Downregulation of the G56R Pathogenic Variant Causing -Associated Autosomal Dominant Retinitis Pigmentosa.

Genes (Basel) 2019 May 10;10(5). Epub 2019 May 10.

Center for Medical Genetics Ghent, Ghent University and Ghent University Hospital, Corneel Heymanslaan 10, 9000 Ghent, Belgium.

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http://dx.doi.org/10.3390/genes10050363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562693PMC
May 2019

Long noncoding RNA expression profiling in cancer: Challenges and opportunities.

Genes Chromosomes Cancer 2019 04 20;58(4):191-199. Epub 2019 Jan 20.

Center for Medical Genetics Ghent (CMGG), Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1002/gcc.22709DOI Listing
April 2019

Two cases of seborrheic keratosis of the external ear canal: involvement of PIK3CA and FGFR3 genes.

Int J Dermatol 2018 Jun 27;57(6):703-706. Epub 2018 Feb 27.

Department of Otorhinolaryngology, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1111/ijd.13943DOI Listing
June 2018

How long noncoding RNAs enforce their will on mitochondrial activity: regulation of mitochondrial respiration, reactive oxygen species production, apoptosis, and metabolic reprogramming in cancer.

Curr Genet 2018 Feb 6;64(1):163-172. Epub 2017 Sep 6.

Center for Medical Genetics, Cancer Research Institute Ghent, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1007/s00294-017-0744-1DOI Listing
February 2018

High-throughput PCR assay design for targeted resequencing using primerXL.

BMC Bioinformatics 2017 Sep 6;18(1):400. Epub 2017 Sep 6.

Center for Medical Genetics, Ghent University, De Pintelaan 185, 9000, Ghent, Belgium.

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http://dx.doi.org/10.1186/s12859-017-1809-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588703PMC
September 2017

decodeRNA- predicting non-coding RNA functions using guilt-by-association.

Database (Oxford) 2017 01;2017

Center for Medical Genetics Ghent (CMGG), Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1093/database/bax042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502368PMC
January 2017

Targeted resequencing and variant validation using pxlence PCR assays.

Biomol Detect Quantif 2016 Jan 9;6:22-6. Epub 2015 Oct 9.

Center for Medical Genetics, Ghent University, Ghent, Belgium; pxlence, Dendermonde, Belgium.

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http://dx.doi.org/10.1016/j.bdq.2015.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822215PMC
January 2016

RDML-Ninja and RDMLdb for standardized exchange of qPCR data.

BMC Bioinformatics 2015 Jun 20;16:197. Epub 2015 Jun 20.

Genomics Core Facility, European Molecular Biology Laboratory, Heidelberg, 69117, Germany.

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http://dx.doi.org/10.1186/s12859-015-0637-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474546PMC
June 2015

Target enrichment using parallel nanoliter quantitative PCR amplification.

BMC Genomics 2014 Mar 10;15:184. Epub 2014 Mar 10.

Center of Medical Genetics Ghent, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1186/1471-2164-15-184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234423PMC
March 2014

Histone chaperone CHAF1A inhibits differentiation and promotes aggressive neuroblastoma.

Cancer Res 2014 Feb 12;74(3):765-74. Epub 2013 Dec 12.

Authors' Affiliations: Texas Children's Cancer Center and Center for Cell and Gene Therapy; Department of Surgery, Baylor College of Medicine, Houston, Texas; Center for Medical Genetics, Ghent University, Ghent, Belgium; CEINGE Biotecnologie Avanzate, Department of Biochemistry and Medical Biotechnology, University of Naples Federico II, Naples; Pediatric Research Institute, University of Padua, Padua; Paediatric Oncology and Haematology Unit "Lalla Seràgnoli," Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy; and Department of Oncogenomics, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

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http://cancerres.aacrjournals.org/content/74/3/765.full.pdf
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http://cancerres.aacrjournals.org/content/early/2013/12/12/0
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-13-1315DOI Listing
February 2014

Single-nucleotide polymorphisms and other mismatches reduce performance of quantitative PCR assays.

Clin Chem 2013 Oct 6;59(10):1470-80. Epub 2013 Sep 6.

Center for Medical Genetics Ghent, Ghent University, Ghent, Belgium;

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http://dx.doi.org/10.1373/clinchem.2013.203653DOI Listing
October 2013

Regulatory microRNA network identification in bovine blastocyst development.

Stem Cells Dev 2013 Jul 15;22(13):1907-20. Epub 2013 Mar 15.

Department of Nutrition, Genetics and Ethology, Ghent University, Merelbeke, Belgium.

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https://www.liebertpub.com/doi/10.1089/scd.2012.0708
Publisher Site
http://dx.doi.org/10.1089/scd.2012.0708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685315PMC
July 2013

The microRNA body map: dissecting microRNA function through integrative genomics.

Nucleic Acids Res 2011 Nov 10;39(20):e136. Epub 2011 Aug 10.

Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium and Life Technologies, Foster City, CA, USA.

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http://dx.doi.org/10.1093/nar/gkr646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203610PMC
November 2011

Measurable impact of RNA quality on gene expression results from quantitative PCR.

Nucleic Acids Res 2011 May 11;39(9):e63. Epub 2011 Feb 11.

Centre for Medical Genetics, Ghent University Hospital, De Pintelaan 185, B-9000 Ghent, Belgium.

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http://dx.doi.org/10.1093/nar/gkr065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089491PMC
May 2011

CEP290, a gene with many faces: mutation overview and presentation of CEP290base.

Hum Mutat 2010 Oct;31(10):1097-108

Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1002/humu.21337DOI Listing
October 2010

Analysing 454 amplicon resequencing experiments using the modular and database oriented Variant Identification Pipeline.

BMC Bioinformatics 2010 May 20;11:269. Epub 2010 May 20.

Laboratory for Bioinformatics and Computational Genomics, Department of Molecular Biotechnology, Ghent University, 9000 Ghent, Belgium.

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http://dx.doi.org/10.1186/1471-2105-11-269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880033PMC
May 2010

methGraph: a genome visualization tool for PCR-based methylation assays.

Epigenetics 2010 Feb 11;5(2):159-63. Epub 2010 Feb 11.

Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.4161/epi.5.2.11161DOI Listing
February 2010

RDML: structured language and reporting guidelines for real-time quantitative PCR data.

Nucleic Acids Res 2009 Apr 17;37(7):2065-9. Epub 2009 Feb 17.

Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1093/nar/gkp056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673419PMC
April 2009

RTPrimerDB: the portal for real-time PCR primers and probes.

Nucleic Acids Res 2009 Jan 23;37(Database issue):D942-5. Epub 2008 Oct 23.

Center for Medical Genetics, Ghent University Hospital, De Pintelaan 185, 9000 Gent, Belgium.

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http://dx.doi.org/10.1093/nar/gkn777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686610PMC
January 2009