Stephen S Hecht

Stephen S Hecht

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Stephen S Hecht

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Differences in exposure to toxic and/or carcinogenic volatile organic compounds between Black and White cigarette smokers.

J Expo Sci Environ Epidemiol 2019 Aug 12. Epub 2019 Aug 12.

Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC, USA.

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http://dx.doi.org/10.1038/s41370-019-0159-9DOI Listing
August 2019

Mass Spectrometric Quantitation of Pyridyloxobutyl DNA Phosphate Adducts in Rats Chronically Treated with N'-Nitrosonornicotine.

Chem Res Toxicol 2019 Apr 26;32(4):773-783. Epub 2019 Feb 26.

Masonic Cancer Center , University of Minnesota , Minneapolis , Minnesota 55455 , United States.

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http://dx.doi.org/10.1021/acs.chemrestox.9b00007DOI Listing
April 2019

Methyl DNA Phosphate Adduct Formation in Lung Tumor Tissue and Adjacent Normal Tissue of Lung Cancer Patients.

Carcinogenesis 2019 Mar 12. Epub 2019 Mar 12.

Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.

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https://academic.oup.com/carcin/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/carcin/bgz053DOI Listing
March 2019

Recent Studies on DNA Adducts Resulting from Human Exposure to Tobacco Smoke.

Toxics 2019 Mar 19;7(1). Epub 2019 Mar 19.

Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.3390/toxics7010016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468371PMC
March 2019

FEMA GRAS assessment of natural flavor complexes: Citrus-derived flavoring ingredients.

Food Chem Toxicol 2019 Feb 24;124:192-218. Epub 2018 Nov 24.

Scientific Secretary to the FEMA Expert Panel, 1101 17th Street, NW Suite 700, Washington, DC, 20036, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02786915183085
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http://dx.doi.org/10.1016/j.fct.2018.11.052DOI Listing
February 2019

Analysis of Acrolein-Derived 1, N-Propanodeoxyguanosine Adducts in Human Lung DNA from Smokers and Nonsmokers.

Chem Res Toxicol 2019 Feb 30;32(2):318-325. Epub 2019 Jan 30.

Masonic Cancer Center , University of Minnesota , Minneapolis , Minnesota 55455 , United States.

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http://dx.doi.org/10.1021/acs.chemrestox.8b00326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644703PMC
February 2019

The safety evaluation of food flavouring substances: the role of metabolic studies.

Toxicol Res (Camb) 2018 Jul 28;7(4):618-646. Epub 2018 Mar 28.

Flavor and Extract Manufacturers Association , 1101 17th Street , NW Suite 700 , Washington , DC 20036 , USA . Email: ; ; Tel: +1 (202)293-5800.

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http://dx.doi.org/10.1039/c7tx00254hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062396PMC
July 2018

Acrolein Exposure in Hookah Smokers and Non-Smokers Exposed to Hookah Tobacco Secondhand Smoke: Implications for Regulating Hookah Tobacco Products.

Nicotine Tob Res 2018 03;20(4):492-501

Center for Behavioral Epidemiology and Community Health (CBEACH), Graduate School of Public Health, Division of Health Promotion, San Diego State University, San Diego, CA, USA.

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http://dx.doi.org/10.1093/ntr/ntx133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896480PMC
March 2018

Updated procedure for the safety evaluation of natural flavor complexes used as ingredients in food.

Food Chem Toxicol 2018 Mar 31;113:171-178. Epub 2018 Jan 31.

Scientific Secretary to the FEMA Expert Panel, 1101 17th Street, NW Suite 700, Washington, DC, 20036, USA. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2018.01.021DOI Listing
March 2018

Identification and analysis of a mercapturic acid conjugate of indole-3-methyl isothiocyanate in the urine of humans who consumed cruciferous vegetables.

J Chromatogr B Analyt Technol Biomed Life Sci 2018 Jan 2;1072:341-346. Epub 2017 Dec 2.

Masonic Cancer Center, University of Minnesota, 2231 6th Street SE, Minneapolis, MN 55455, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2017.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743587PMC
January 2018

A New Editorial Team for CRT.

Authors:
Stephen S Hecht

Chem Res Toxicol 2018 01 28;31(1). Epub 2017 Dec 28.

Masonic Cancer Center, University of Minnesota , Minneapolis, Minnesota 55455, United States.

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http://dx.doi.org/10.1021/acs.chemrestox.7b00318DOI Listing
January 2018

Ultrasensitive High-Resolution Mass Spectrometric Analysis of a DNA Adduct of the Carcinogen Benzo[a]pyrene in Human Lung.

Anal Chem 2017 12 17;89(23):12735-12742. Epub 2017 Nov 17.

Masonic Cancer Center, University of Minnesota , 2231 Sixth Street SE, Minneapolis, Minnesota 55455, United States.

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http://pubs.acs.org/doi/10.1021/acs.analchem.7b02856
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http://dx.doi.org/10.1021/acs.analchem.7b02856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027747PMC
December 2017

Association of CYP2A6 activity with lung cancer incidence in smokers: The multiethnic cohort study.

PLoS One 2017 25;12(5):e0178435. Epub 2017 May 25.

Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0178435PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444837PMC
September 2017

Tobacco, e-cigarettes, and child health.

Curr Opin Pediatr 2017 Apr;29(2):225-230

Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA.

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http://dx.doi.org/10.1097/MOP.0000000000000456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598780PMC
April 2017

Identification of 4-(3-Pyridyl)-4-oxobutyl-2'-deoxycytidine Adducts Formed in the Reaction of DNA with 4-(Acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone: A Chemically Activated Form of Tobacco-Specific Carcinogens.

ACS Omega 2017 Mar 28;2(3):1180-1190. Epub 2017 Mar 28.

Masonic Cancer Center, University of Minnesota , 2231 6th Street SE, Room 2-148 CCRB, Minneapolis, Minnesota 55455, United States.

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http://dx.doi.org/10.1021/acsomega.7b00072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377278PMC
March 2017

Analysis of N'-nitrosonornicotine enantiomers in human urine by chiral stationary phase liquid chromatography-nanoelectrospray ionization-high resolution tandem mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2017 Feb 9;1044-1045:127-131. Epub 2017 Jan 9.

Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2017.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296371PMC
February 2017

Reduced nicotine content cigarettes and use of alternative nicotine products: exploratory trial.

Addiction 2017 01 2;112(1):156-167. Epub 2016 Nov 2.

Duluth Medical Research Institute, University of Minnesota Medical School, Duluth, MN, USA.

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http://dx.doi.org/10.1111/add.13603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249662PMC
January 2017

Safety evaluation of substituted thiophenes used as flavoring ingredients.

Food Chem Toxicol 2017 Jan 9;99:40-59. Epub 2016 Nov 9.

Flavor and Extract Manufacturers Association, 1101 17th Street, NW Suite 700, Washington, DC, 20036, USA. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2016.10.023DOI Listing
January 2017

A Special Issue of CRT: Celebrating Volume 30.

Authors:
Stephen S Hecht

Chem Res Toxicol 2017 01;30(1)

Masonic Cancer Center, University of Minnesota , Minneapolis, Minnesota 55455, United States.

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http://dx.doi.org/10.1021/acs.chemrestox.6b00440DOI Listing
January 2017

Oral Cell DNA Adducts as Potential Biomarkers for Lung Cancer Susceptibility in Cigarette Smokers.

Authors:
Stephen S Hecht

Chem Res Toxicol 2017 01 1;30(1):367-375. Epub 2016 Dec 1.

Masonic Cancer Center, University of Minnesota , Minneapolis, Minnesota 55455, United States.

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http://dx.doi.org/10.1021/acs.chemrestox.6b00372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310195PMC
January 2017

FEMA expert panel review of p-mentha-1,8-dien-7-al genotoxicity testing results.

Food Chem Toxicol 2016 Dec 20;98(Pt B):201-209. Epub 2016 Oct 20.

Flavor and Extract Manufacturers Association, 1101 17th Street, NW Suite 700, Washington, DC 20036, USA. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2016.10.020DOI Listing
December 2016

Evaluation of Nitrosamide Formation in the Cytochrome P450-Mediated Metabolism of Tobacco-Specific Nitrosamines.

Chem Res Toxicol 2016 12 6;29(12):2194-2205. Epub 2016 Dec 6.

Masonic Cancer Center, University of Minnesota , 2231 Sixth Street SE, 2-210 CCRB, Minneapolis, Minnesota 55455, United States.

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http://dx.doi.org/10.1021/acs.chemrestox.6b00384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785922PMC
December 2016

A Randomized Controlled Trial of Progressively Reduced Nicotine Content Cigarettes on Smoking Behaviors, Biomarkers of Exposure, and Subjective Ratings.

Cancer Epidemiol Biomarkers Prev 2016 07 27;25(7):1125-33. Epub 2016 Apr 27.

Center for Interdisciplinary Research on Nicotine Addiction, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1055-9965.EPI-15-1088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930705PMC
July 2016

Research on cruciferous vegetables, indole-3-carbinol, and cancer prevention: A tribute to Lee W. Wattenberg.

Mol Nutr Food Res 2016 06 23;60(6):1228-38. Epub 2016 May 23.

Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1002/mnfr.201500889DOI Listing
June 2016

Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification.

Drug Metab Dispos 2016 Mar 7;44(3):422-7. Epub 2016 Jan 7.

Department of Medicinal Chemistry, College of Pharmacy (S.C.N., P.L., J.P., C.X.), Masonic Cancer Center (L.B.W., S.G.C., P.U., S.S.H., S.E.M.), and Department of Biochemistry, Molecular Biology and Biophysics (L.B.W., S.E.M.), University of Minnesota, Minneapolis, Minnesota

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http://dx.doi.org/10.1124/dmd.115.068387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767383PMC
March 2016

DNA Adduct Formation from Metabolic 5'-Hydroxylation of the Tobacco-Specific Carcinogen N'-Nitrosonornicotine in Human Enzyme Systems and in Rats.

Chem Res Toxicol 2016 Mar 9;29(3):380-9. Epub 2016 Feb 9.

Masonic Cancer Center, University of Minnesota , 2231 6th Street SE, 2-210 CCRB, Minneapolis, Minnesota 55455, United States.

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http://dx.doi.org/10.1021/acs.chemrestox.5b00520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805523PMC
March 2016

Elevated levels of mercapturic acids of acrolein and crotonaldehyde in the urine of Chinese women in Singapore who regularly cook at home.

PLoS One 2015 25;10(3):e0120023. Epub 2015 Mar 25.

Division of Cancer Control and Population Sciences, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120023PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373935PMC
February 2016

Analysis of O(6)-[4-(3-Pyridyl)-4-oxobut-1-yl]-2'-deoxyguanosine and Other DNA Adducts in Rats Treated with Enantiomeric or Racemic N'-Nitrosonornicotine.

Chem Res Toxicol 2016 Jan 18;29(1):87-95. Epub 2015 Dec 18.

Masonic Cancer Center, University of Minnesota , Minneapolis, Minnesota 55455, United States.

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http://dx.doi.org/10.1021/acs.chemrestox.5b00425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168933PMC
January 2016

Exposure and Metabolic Activation Biomarkers of Carcinogenic Tobacco-Specific Nitrosamines.

Acc Chem Res 2016 Jan 17;49(1):106-14. Epub 2015 Dec 17.

Masonic Cancer Center, University of Minnesota , 2231 Sixth Street SE, 2-148 CCRB, Minneapolis, Minnesota 55455, United States.

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http://dx.doi.org/10.1021/acs.accounts.5b00472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154679PMC
January 2016

Screening for DNA Alkylation Mono and Cross-Linked Adducts with a Comprehensive LC-MS(3) Adductomic Approach.

Anal Chem 2015 Dec 10;87(23):11706-13. Epub 2015 Nov 10.

Masonic Cancer Center, University of Minnesota , 2231 Sixth Street SE, Minneapolis, Minnesota 55455, United States.

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http://dx.doi.org/10.1021/acs.analchem.5b02759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126974PMC
December 2015

Benzene oxide is a substrate for glutathione S-transferases.

Chem Biol Interact 2015 Dec 7;242:390-5. Epub 2015 Nov 7.

Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA; Medicinal Chemistry Graduate Program, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1016/j.cbi.2015.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695229PMC
December 2015

Combined analysis of N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in the urine of cigarette smokers and e-cigarette users.

J Chromatogr B Analyt Technol Biomed Life Sci 2015 Dec 31;1007:121-6. Epub 2015 Oct 31.

Masonic Cancer Center, University of Minnesota Minneapolis, MN 55455, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2015.10.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697455PMC
December 2015

Randomized Trial of Reduced-Nicotine Standards for Cigarettes.

N Engl J Med 2015 Oct;373(14):1340-9

From the Departments of Psychology (E.C.D., R.L.D., S.S.D., T.L.) and Medicine (H.T.), University of Pittsburgh, Pittsburgh; the Center for Alcohol and Addiction Studies, Brown University, Providence, RI (J.W.T.); the Division of Biostatistics, School of Public Health (J.S.K., C.T.L.), the Departments of Biochemistry, Molecular Biology, and Biophysics (S.E.M.) and Psychiatry (D.K.H.) and the Masonic Cancer Center (J.S.K., S.G.C., S.S.H., J.J., C.T.L., S.E.M., D.K.H.), University of Minnesota, Minneapolis, and the University of Minnesota Medical School, Duluth (M.A.) - all in Minnesota; the Departments of Medicine and Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco (N.L.B.); the Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore (R.G.V., M.L.S.), and National Institute on Drug Abuse, Bethesda (I.D.M.) - both in Maryland; the Department of Behavioral Science, University of Texas M.D. Anderson Cancer Center, Houston (P.M.C., J.D.R.); the Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, FL (D.J.D.); the Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC (F.J.M.); and the Department of Psychiatry, Perelman School of Medicine, and Abramson Cancer Center, University of Pennsylvania, Philadelphia (A.A.S.).

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http://dx.doi.org/10.1056/NEJMsa1502403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642683PMC
October 2015

Quantitative analysis of 3'-hydroxynorcotinine in human urine.

Nicotine Tob Res 2015 May 16;17(5):524-9. Epub 2014 Oct 16.

Masonic Cancer Center, University of Minnesota, Minneapolis, MN

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http://dx.doi.org/10.1093/ntr/ntu206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402357PMC
May 2015

Combined analysis of the tobacco metabolites cotinine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in human urine.

Anal Chem 2015 Feb 14;87(3):1514-7. Epub 2015 Jan 14.

Masonic Cancer Center, University of Minnesota , 2231 6th Street SE, 2-148 CCRB, Minneapolis, Minnesota 55455, United States.

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http://dx.doi.org/10.1021/ac504047jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315695PMC
February 2015

Quantitation of enantiomers of r-7,t-8,9,c-10-tetrahydroxy-7,8,9,10-tetrahydrobenzo[a]-pyrene in human urine: evidence supporting metabolic activation of benzo[a]pyrene via the bay region diol epoxide.

Mutagenesis 2014 Sep 21;29(5):351-6. Epub 2014 Jul 21.

Masonic Cancer Center andDepartment of Laboratory Medicine and Pathology, University of Minnesota, 2231 6th Street SE, 2-148 CCRB, Minneapolis, MN 55105, USA.

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http://dx.doi.org/10.1093/mutage/geu024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141684PMC
September 2014

Children's exposure to secondhand and thirdhand smoke carcinogens and toxicants in homes of hookah smokers.

Nicotine Tob Res 2014 Jul 3;16(7):961-75. Epub 2014 Mar 3.

Center for Behavioral Epidemiology and Community Health, Graduate School of Public Health, Division of Health Promotion, San Diego State University, San Diego, CA;

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http://dx.doi.org/10.1093/ntr/ntu016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072898PMC
July 2014

Liver tumor promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxin is dependent on the aryl hydrocarbon receptor and TNF/IL-1 receptors.

Toxicol Sci 2014 Jul 9;140(1):135-43. Epub 2014 Apr 9.

McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, Wisconsin 53706

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http://dx.doi.org/10.1093/toxsci/kfu065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133587PMC
July 2014

It is time to regulate carcinogenic tobacco-specific nitrosamines in cigarette tobacco.

Authors:
Stephen S Hecht

Cancer Prev Res (Phila) 2014 Jul 7;7(7):639-47. Epub 2014 May 7.

Author's Affiliation: Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota

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http://dx.doi.org/10.1158/1940-6207.CAPR-14-0095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135519PMC
July 2014

Chemoprevention of esophageal cancer with black raspberries, their component anthocyanins, and a major anthocyanin metabolite, protocatechuic acid.

Cancer Prev Res (Phila) 2014 Jun 25;7(6):574-84. Epub 2014 Mar 25.

Authors' Affiliations: Departments of Medicine, Pathology, and Obstetrics and Gynecology, Medical College of Wisconsin Cancer Center; Agro BioSciences Inc., Milwaukee, Wisconsin; and Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota

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http://cancerpreventionresearch.aacrjournals.org/cgi/doi/10.
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http://dx.doi.org/10.1158/1940-6207.CAPR-14-0003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108893PMC
June 2014

Tobacco-specific N-nitrosamine exposures and cancer risk in the Shanghai Cohort Study: remarkable coherence with rat tumor sites.

Int J Cancer 2014 May 18;134(10):2278-83. Epub 2013 Nov 18.

Division of Environmental Health Sciences, University of Minnesota, Minneapolis, MN; Masonic Cancer Center, University of Minnesota, Minneapolis, MN.

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http://dx.doi.org/10.1002/ijc.28575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949147PMC
May 2014

GRASr2 evaluation of aliphatic acyclic and alicyclic terpenoid tertiary alcohols and structurally related substances used as flavoring ingredients.

J Food Sci 2014 Apr 1;79(4):R428-41. Epub 2014 Apr 1.

Dept. of Biochemistry, Center in Molecular Toxicology, Vanderbilt University, School of Medicine, Nashville, TN 37232-0146, U.S.A.

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http://dx.doi.org/10.1111/1750-3841.12407DOI Listing
April 2014

Effect of cigarette smoking on urinary 2-hydroxypropylmercapturic acid, a metabolite of propylene oxide.

J Chromatogr B Analyt Technol Biomed Life Sci 2014 Mar 14;953-954:126-31. Epub 2014 Feb 14.

Masonic Cancer Center, University of Minnesota, 2231 6th Street SE, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1016/j.jchromb.2014.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993985PMC
March 2014

Urinary 3,3'-diindolylmethane: a biomarker of glucobrassicin exposure and indole-3-carbinol uptake in humans.

Cancer Epidemiol Biomarkers Prev 2014 Feb 19;23(2):282-7. Epub 2013 Dec 19.

Authors' Affiliations: Divisions of Hematology, Oncology, and Transplantation and Epidemiology and Community Health; Masonic Cancer Center, and Departments of Urology and Psychiatry, University of Minnesota, Minneapolis; Departments of Food Science and Nutrition and Horticultural Science, University of Minnesota, St. Paul; and Southern Research and Outreach Center, University of Minnesota, Waseca, Minnesota.

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http://dx.doi.org/10.1158/1055-9965.EPI-13-0645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935417PMC
February 2014

Application of a high-resolution mass-spectrometry-based DNA adductomics approach for identification of DNA adducts in complex mixtures.

Anal Chem 2014 Feb 21;86(3):1744-52. Epub 2014 Jan 21.

Masonic Cancer Center, University of Minnesota , 2231 6th Street SE, Minneapolis, MN 55455.

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http://dx.doi.org/10.1021/ac403565mDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982966PMC
February 2014

Clinical and biochemical studies support smokeless tobacco's carcinogenic potential in the human oral cavity.

Cancer Prev Res (Phila) 2014 Jan 21;7(1):23-32. Epub 2013 Nov 21.

Division of Oral Maxillofacial Pathology and Radiology, College of Dentistry, The Ohio State University, 2191B Postle Hall, 305 W12th Avenue, Columbus, OH 43210.

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http://dx.doi.org/10.1158/1940-6207.CAPR-13-0262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892990PMC
January 2014

Fifty years of tobacco carcinogenesis research: from mechanisms to early detection and prevention of lung cancer.

Cancer Prev Res (Phila) 2014 Jan;7(1):1-8

University of Minnesota, 2231 6th Street Southeast, Room 2-148 CCRB, Minneapolis, MN 55455. Phone: 612-624-7604; Fax: 612-624-3869; and Eva Szabo, Lung and Upper Aerodigestive Cancer Research Group, Division of Cancer Prevention, National Cancer Institute, NIH, HHS, 9609 Medical Center Drive, Room 5E-102, Bethesda, MD 20892.

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http://dx.doi.org/10.1158/1940-6207.CAPR-13-0371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296669PMC
January 2014

Urinary tobacco smoke-constituent biomarkers for assessing risk of lung cancer.

Cancer Res 2014 Jan 9;74(2):401-11. Epub 2014 Jan 9.

Authors' Affiliations: Division of Cancer Control and Population Sciences, University of Pittsburgh Cancer Institute; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; and Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-3178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066207PMC
January 2014

Introducing Perspectives on Statistical Trends (POST).

Authors:
Stephen S Hecht

Chem Res Toxicol 2013 Dec;26(12):1775

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http://dx.doi.org/10.1021/tx400413xDOI Listing
December 2013

Continuing excellence for chemical research in toxicology.

Authors:
Stephen S Hecht

Chem Res Toxicol 2013 Jan;26(1)

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http://dx.doi.org/10.1021/tx300497eDOI Listing
January 2013