Publications by authors named "Stephen Opat"

63Publications

Caution in Expanding the Use of Abbreviated R-CHOP to Poor-Risk Limited-Stage DLBCL.

J Clin Oncol 2020 Oct 26:JCO2002301. Epub 2020 Oct 26.

Eliza A. Hawkes, MBBS, DMedSc, Department of Clinical Haematology and Medical Oncology, Olivia Newton-John Cancer Research Institute at Austin Health, Heidelberg, Victoria, Australia; Stephen Opat, MBBS, Clinical Haematology, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia; and Mark Hertzberg, MBBS, PhD, Department of Haematology, Prince of Wales Hospital and University of New South Wales, Randwick, New South Wales, Australia.

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http://dx.doi.org/10.1200/JCO.20.02301DOI Listing
October 2020

Impact of coronavirus disease 2019 (COVID-19) pandemic isolation measures on the rate of non-COVID-19 infections in hematology patients.

Infect Control Hosp Epidemiol 2020 Oct 20:1-3. Epub 2020 Oct 20.

Monash University School of Clinical Sciences, Monash Health, Victoria, Australia.

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http://dx.doi.org/10.1017/ice.2020.1279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653225PMC
October 2020

An update of venetoclax and obinutuzumab in chronic lymphocytic leukemia.

Future Oncol 2020 Oct 16. Epub 2020 Oct 16.

Department of Haematology, Monash Health, 246 Clayton Rd, Clayton, Victoria 3168, Australia; School of Clinical Sciences at Monash Health, Monash University, Wellington Rd, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.2217/fon-2020-0640DOI Listing
October 2020

Persistently positive culture of antimicrobial-susceptible despite appropriate therapy.

Access Microbiol 2020 2;2(5):acmi000113. Epub 2020 Mar 2.

Monash Infectious Diseases, Monash Health, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1099/acmi.0.000113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494184PMC
March 2020

Failure of tofacitinib to achieve an objective response in a T-lymphoblastic leukemia with activating mutations.

Cold Spring Harb Mol Case Stud 2020 Aug 25;6(4). Epub 2020 Aug 25.

Department of Hematology, Monash Health, Clayton, 3168, Victoria, Australia.

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http://dx.doi.org/10.1101/mcs.a004994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476415PMC
August 2020

A consensus statement on the use of biosimilar medicines in hematology in Australia.

Asia Pac J Clin Oncol 2020 Aug 14;16(4):211-221. Epub 2020 Apr 14.

Monash Haematology, Monash Health, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1111/ajco.13337DOI Listing
August 2020

A practical guide to laboratory investigations at diagnosis and follow up in Waldenström macroglobulinaemia: recommendations from the Medical and Scientific Advisory Group, Myeloma Australia, the Pathology Sub-committee of the Lymphoma and Related Diseases Registry and the Australasian Association of Clinical Biochemists Monoclonal Gammopathy Working Group.

Pathology 2020 Feb 3;52(2):167-178. Epub 2020 Jan 3.

Department of Haematology, ACT Pathology, Canberra Hospital, ACT, Australia; ANU Medical School, College of Medicine and Health, Australian National University, Canberra, ACT, Australia; Medical and Scientific Advisory Group, Myeloma Australia; Pathology Sub-committee of the Lymphoma and Related Diseases Registry (LaRDR), Australia. Electronic address:

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http://dx.doi.org/10.1016/j.pathol.2019.11.002DOI Listing
February 2020

Efficacy of Zanubrutinib in the Treatment of Bing-Neel Syndrome.

Hemasphere 2018 Dec 30;2(6):e155. Epub 2018 Nov 30.

Department of Hematology, Monash Health, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1097/HS9.0000000000000155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745965PMC
December 2018

Author reply.

Intern Med J 2019 10;49(10):1338-1339

Clinical Haematology and School of Clinical Sciences, Monash Health, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/imj.14460DOI Listing
October 2019

Venetoclax and Obinutuzumab in Patients with CLL and Coexisting Conditions.

N Engl J Med 2019 Jun 4;380(23):2225-2236. Epub 2019 Jun 4.

From Department I of Internal Medicine, Center for Integrated Oncology Aachen-Bonn-Cologne-Duesseldorf, University Hospital Cologne and University of Cologne (K.F., O.A.-S., J.B., A.-M.F., S. Robrecht, B.E., K.-A.K., M.H.), the Oncogeriatric Unit, Department of Geriatric Medicine, St. Marien Hospital (V.G.), CECAD (Center of Excellence on Cellular Stress Responses in Aging-Associated Diseases) (M.H.), Center for Molecular Medicine Cologne (M.H.), Cologne, Department III of Internal Medicine, University Hospital Rostock, Rostock (S.B.), Department III of Internal Medicine, Ulm University, Ulm (E.T., S.S.), the Departments of Hematology, Oncology, Immunology, Palliative Care, Infectious Diseases, and Tropical Medicine, Klinikum Schwabing, Munich (C.-M.W.), Department II of Internal Medicine, Campus Kiel, University of Schleswig-Holstein, Kiel (M.R.), and the Department of Hematology, Oncology, and Rheumatology, Saarland University Medical School, Homburg (S.S.) - all in Germany; Roche Products, Welwyn Garden City, United Kingdom (M.T., M.D., S.W., K.H.); Regional Clinical Hospital N.A. Semashko, Nizhny Novgorod, Russia (O.S.); the Division of Onco-Hematology, Santa Maria Terni Hospital, University of Perugia, Perugia, Italy (A.M.L.); the Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL (J.P.-I.); the Haematology Department, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia (S.O.); First Internal Department, Multiprofile Hospital for Active Treatment Hristo Botev, Vratsa, Bulgaria (L.S.); the Hematology Department, Clinique Victor Hugo, Le Mans, France (K.L.D.); Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil (L.M.F.); the Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen (C.U.N.); Wellington Blood and Cancer Centre, Capital and Coast District Health Board, and Malaghan Institute of Medical Research, Wellington, New Zealand (R.W.); Queen Elizabeth II Health Sciences Centre, Halifax, NS, Canada (S. Robinson); Moores Cancer Center, University of California San Diego, San Diego (T.J.K.), and Genentech, South San Francisco (M.M.) - both in California; AbbVie, North Chicago, IL (R.H.); and the Department of Immunology, Laboratory Medical Immunology, Erasmus MC, Rotterdam, the Netherlands (A.W.L.).

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http://www.nejm.org/doi/10.1056/NEJMoa1815281
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http://dx.doi.org/10.1056/NEJMoa1815281DOI Listing
June 2019

Management of patients with follicular lymphoma treated first line with obinutuzumab.

Asia Pac J Clin Oncol 2019 May;15 Suppl 3:3-11

Haematology Department, Concord Hospital, University of Sydney, Concord, NSW, Australia.

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http://dx.doi.org/10.1111/ajco.13153DOI Listing
May 2019

Front-line management of indolent non-Hodgkin lymphoma in Australia. Part 2: mantle cell lymphoma and marginal zone lymphoma.

Intern Med J 2019 09;49(9):1070-1080

Division of Cancer Services, Clinical Haematology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1111/imj.14268DOI Listing
September 2019

Bleeding and thrombotic events occur early in children on durable ventricular assist devices.

Thromb Res 2019 01 22;173:65-70. Epub 2018 Nov 22.

Murdoch Children's Research Institute, Hematology Research Group, Parkville, Victoria, Australia; Royal Children's Hospital, Department of Clinical Hematology, Parkville, Victoria, Australia; University of Melbourne, Department of Pediatrics, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1016/j.thromres.2018.11.019DOI Listing
January 2019

Front-line management of non-Hodgkin lymphoma in Australia. Part 1: follicular lymphoma.

Intern Med J 2019 04;49(4):422-433

Clinical Haematology and School of Clinical Sciences, Monash Health, Victoria, Australia.

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http://dx.doi.org/10.1111/imj.14113DOI Listing
April 2019

Concurrent Mycobacterium tuberculosis infection and nodal marginal zone lymphoma.

Pathology 2018 Jun 3;50(4):464-466. Epub 2018 May 3.

Department of Clinical Haematology, Monash Health, Clayton, Vic, Australia.

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http://dx.doi.org/10.1016/j.pathol.2017.10.023DOI Listing
June 2018

Chemoimmunotherapy May Not Be Dead Yet in Chronic Lymphocytic Leukemia, But Fludarabine Plus Cyclophosphamide Plus Rituximab Is Potentially Facing Life Support.

J Clin Oncol 2017 12 3;35(36):4093-4094. Epub 2017 Nov 3.

Stephen Opat, Monash Health, Clayton, Australia; Monash University, Melbourne, Australia; and Eliza A. Hawkes, Monash University, Melbourne, Australia; Austin Health, Heidelberg, Australia; Eastern Health, Box Hill, Australia.

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http://dx.doi.org/10.1200/JCO.2017.75.4721DOI Listing
December 2017

Obinutuzumab for the First-Line Treatment of Follicular Lymphoma.

N Engl J Med 2017 10;377(14):1331-1344

From King's College Hospital (R.M.) and the Cancer Research UK and University College London Cancer Trials Centre (E.P., W.T.), London, and the Cancer Research UK Centre, University of Southampton, Southampton (A.D.) - all in the United Kingdom; the Tokai University School of Medicine, Isehara, Japan (K.A.); the University of Kiel, Kiel (W.K.), Gemeinschaftspraxis, Würzburg (R. Schlag), HELIOS Klinikum Erfurt, Erfurt (M.H.), and the Ludwig-Maximilians-University Hospital Grosshadern, Munich (W.H.) - all in Germany; Monash Health and Monash University (S.O.) and the Peter MacCallum Cancer Centre and University of Melbourne (J.F.S.), Melbourne, VIC, Australia; Foothills Medical Centre and Tom Baker Cancer Centre, Calgary, AB (C.O.), and the Cross Cancer Institute, Edmonton, AB (R. Sangha) - both in Canada; Charles University, Prague, Czech Republic (M.T.); and F. Hoffmann-La Roche, Basel, Switzerland (M.W., G.F.-R., K.R., T.M.).

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http://dx.doi.org/10.1056/NEJMoa1614598DOI Listing
October 2017

Management of patients with previously untreated chronic lymphocytic leukaemia with obinutuzumab and chlorambucil.

Intern Med J 2017 Jul;47 Suppl 4:5-10

Department of Haematology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1111/imj.13493DOI Listing
July 2017

Infection is an Independent Predictor of Death in Diffuse Large B Cell Lymphoma.

Sci Rep 2017 06 30;7(1):4395. Epub 2017 Jun 30.

Monash Haematology, Monash Health, Level 4, Monash Medical Centre, 246 Clayton Road, Clayton, VIC 3168, Australia.

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http://dx.doi.org/10.1038/s41598-017-04495-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493675PMC
June 2017

High-dose therapy and autologous stem cell transplantation may only be applicable to selected patients with secondary CNS diffuse large B-cell lymphoma.

Br J Haematol 2017 09 29;178(6):991-994. Epub 2016 Jul 29.

Peter MacCallum Cancer Centre, St Andrews Place, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/bjh.14187DOI Listing
September 2017

Infusional dose-adjusted epoch plus bortezomib for the treatment of plasmablastic lymphoma.

Ann Hematol 2016 Mar 23;95(4):667-8. Epub 2016 Jan 23.

Monash Haematology, Monash Medical Centre, Level 4, 246 Clayton Road, Clayton, VIC, Australia, 3168.

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http://dx.doi.org/10.1007/s00277-016-2601-6DOI Listing
March 2016

The oral iron chelator deferasirox inhibits NF-κB mediated gene expression without impacting on proximal activation: implications for myelodysplasia and aplastic anaemia.

Br J Haematol 2015 Feb 1;168(4):576-82. Epub 2014 Oct 1.

Centre for Cancer Research, MIMR-PHI Institute of Medical Research, Clayton, Vic., Australia; Centre for Inflammatory Diseases, Monash University, Clayton, Vic., Australia.

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http://dx.doi.org/10.1111/bjh.13151DOI Listing
February 2015

N-Acetylcysteine for thrombotic thrombocytopenic purpura: is a von Willebrand factor-inhibitory dose feasible in vivo?

Transfusion 2014 Sep;54(9):2362-3

Monash Haematology, Monash University, Clayton, Victoria, Australia; Southern Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1111/trf.12787DOI Listing
September 2014

Obinutuzumab plus chlorambucil in patients with CLL and coexisting conditions.

N Engl J Med 2014 Mar 8;370(12):1101-10. Epub 2014 Jan 8.

From the German CLL Study Group, Department I of Internal Medicine, Center of Integrated Oncology Cologne-Bonn, University Hospital Cologne, Cologne (V.G., K.F., A.E., B.E., C.M.W., K.-A.K., M.H.), the Department for Geriatric Medicine and Research, St. Marien Hospital and University of Cologne, Cologne (V.G.), Institute of Medical Statistics and Epidemiology, Technical University Munich, Munich (R.B.), Klinikum Schwabing, Munich (C.M.W.), private oncology practice, Dresden (T.I.), Medical Department II, University of Schleswig-Holstein, City Hospital Kiel, Kiel (M.R., M.K.), the Department of Internal Medicine III, Ulm University, Ulm (S.S., H.D.), and Cluster of Excellence "Cellular Stress Responses in Aging-Associated Diseases" (CECAD), University of Cologne, Cologne (M.H.) - all in Germany; Penza Regional Oncology Dispensary, Penza (T.C.), and Regional Clinical Hospital N.A. Semashko, Nizhny Novgorod (O.S.) - both in Russia; Servicio De Hematologia, Hospital Universitario 12 De Octubre, Madrid (J.S.); Hôpital Haut Lévêque, Bordeaux, Pessac, France (M.-S.D.); the Department of Haematology, Monash Medical Centre, Clayton, Australia (S.O.); University of Calgary, Calgary, AB, Canada (C.J.O.); the Department of Immunology, Erasmus Medical Center Rotterdam, Rotterdam, the Netherlands (A.W.L.); F. Hoffmann-La Roche, Basel, Switzerland (E.A.); F. Hoffmann-La Roche, Welwyn, United Kingdom (K.H.); and Genentech, South San Francisco, CA (M.W.).

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http://dx.doi.org/10.1056/NEJMoa1313984DOI Listing
March 2014

Factor XIII assays.

Methods Mol Biol 2013 ;992:171-80

Department of Haematology, Monash Medical Centre, Clayton, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-62703-339-8_13DOI Listing
September 2013

Rituximab is associated with improved survival for aggressive B cell CNS lymphoma.

Neuro Oncol 2013 Aug 15;15(8):1068-73. Epub 2013 Mar 15.

Inter-hospital Multi-institution Project Alliance and Collaboration Taskforce, Monash Medical Centre, Clayton, Australia.

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http://dx.doi.org/10.1093/neuonc/not032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714147PMC
August 2013

Complete remission of localised gastric plasmacytomas following definitive radiotherapy.

J Med Imaging Radiat Oncol 2012 Jun 10;56(3):328-31. Epub 2012 Apr 10.

Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/j.1754-9485.2012.02369.xDOI Listing
June 2012

Serum protein electrophoresis: a precautionary tale.

Pathology 2012 Jun;44(4):371-373

Department of Clinical Haematology, Southern Health, Clayton, Australia.

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http://dx.doi.org/10.1097/PAT.0b013e328353be32DOI Listing
June 2012

Failure of eculizumab to correct paroxysmal cold hemoglobinuria.

Ann Hematol 2011 Aug 26;90(8):989-90. Epub 2010 Nov 26.

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http://dx.doi.org/10.1007/s00277-010-1123-xDOI Listing
August 2011

Refractory Bartonella quintana bacillary angiomatosis following chemotherapy for chronic lymphocytic leukaemia.

J Med Microbiol 2011 Jan 14;60(Pt 1):142-146. Epub 2010 Oct 14.

Department of Medicine, Monash University, Clayton, VIC 3168, Australia.

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http://jmm.microbiologyresearch.org/content/journal/jmm/10.1
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http://dx.doi.org/10.1099/jmm.0.015867-0DOI Listing
January 2011

A case of ITP with cauda equina syndrome.

Ann Hematol 2011 Jun 18;90(6):729-30. Epub 2010 Sep 18.

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http://dx.doi.org/10.1007/s00277-010-1075-1DOI Listing
June 2011

Aplastic anaemia: autoimmune sequel of thymoma.

Br J Haematol 2009 Dec 5;147(5):591. Epub 2009 May 5.

Department of Haematology, Monash Medical Centre, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1111/j.1365-2141.2009.07716.xDOI Listing
December 2009

Bone marrow engraftment in pulmonary vessels.

Br J Haematol 2009 Jun 8;146(1). Epub 2009 Jan 8.

Department of Haematology, Monash Medical Centre, Melbourne, Australia.

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http://dx.doi.org/10.1111/j.1365-2141.2008.07544.xDOI Listing
June 2009

Clinical and immunohistochemical features associated with a response to bortezomib in patients with multiple myeloma.

Clin Cancer Res 2009 Jan;15(2):714-22

Clinical Haematology/Bone Marrow Transplant Department, The Alfred Hospital, Commercial Road, Prahran, Melbourne, Victoria, Australia 3181.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-1022DOI Listing
January 2009

Oxidative haemolysis due to 'poppers'.

Br J Haematol 2008 Jul 8;142(3):328. Epub 2008 May 8.

Haematology Unit, Alfred Pathology Service, The Alfred Hospital, Melbourne, Vic., Australia.

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http://dx.doi.org/10.1111/j.1365-2141.2008.07150.xDOI Listing
July 2008

The PRKAR1A gene is fused to RARA in a new variant acute promyelocytic leukemia.

Blood 2007 Dec 21;110(12):4073-6. Epub 2007 Aug 21.

Institute of Haematology, Royal Prince Alfred Hospital, Sydney, Australia.

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http://dx.doi.org/10.1182/blood-2007-06-095554DOI Listing
December 2007

Antiplatelet therapy: present status and future prospects.

Expert Opin Drug Discov 2007 Aug;2(8):1035-40

Australian Centre for Blood Diseases, Monash University, 6th Level, Burnet Building, AMREP Campus, 89 Commercial Road, Melbourne, Victoria 3004, Australia +61 3 9903 0122 ; +61 3 9903 0228 ;

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http://dx.doi.org/10.1517/17460441.2.8.1035DOI Listing
August 2007

Antioxidant therapy for severe cardiac failure induced by iron overload secondary to dyserythropoietic anaemia.

Heart Lung Circ 2007 Oct 20;16(5):394-7. Epub 2007 Feb 20.

Department of Cardiothoracic Surgery, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1016/j.hlc.2006.12.010DOI Listing
October 2007

An unusual case of indigestion: persistence of phagocytosed Auer rods in acute promyelocytic leukaemia.

Br J Haematol 2006 Apr;133(2):112

Haematology Unit, Alfred Pathology Service, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/j.1365-2141.2006.06011.xDOI Listing
April 2006