Stephen Meader

Stephen Meader

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Stephen Meader

Stephen Meader

Publications by authors named "Stephen Meader"

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14Publications

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Haploinsufficiency predictions without study bias.

Nucleic Acids Res 2015 Sep 22;43(15):e101. Epub 2015 May 22.

MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, UK

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http://dx.doi.org/10.1093/nar/gkv474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551909PMC
September 2015

Unbiased functional clustering of gene variants with a phenotypic-linkage network.

PLoS Comput Biol 2014 Aug 28;10(8):e1003815. Epub 2014 Aug 28.

MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.

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http://dx.plos.org/10.1371/journal.pcbi.1003815
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http://dx.doi.org/10.1371/journal.pcbi.1003815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148192PMC
August 2014

8.2% of the Human genome is constrained: variation in rates of turnover across functional element classes in the human lineage.

PLoS Genet 2014 Jul 24;10(7):e1004525. Epub 2014 Jul 24.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1004525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109858PMC
July 2014

Clinical significance of de novo and inherited copy-number variation.

Hum Mutat 2013 Dec 10;34(12):1679-87. Epub 2013 Oct 10.

Department of Human Genetics, Nijmegen Centre for Molecular Life Sciences and Institute for Genetic and Metabolic Disorders, Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/humu.22442DOI Listing
December 2013

Rapid turnover of functional sequence in human and other genomes.

Annu Rev Genomics Hum Genet 2011 ;12:275-99

Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford OX1 3QX, United Kingdom.

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http://dx.doi.org/10.1146/annurev-genom-090810-183115DOI Listing
October 2011

Comparative and demographic analysis of orang-utan genomes.

Authors:
Devin P Locke LaDeana W Hillier Wesley C Warren Kim C Worley Lynne V Nazareth Donna M Muzny Shiaw-Pyng Yang Zhengyuan Wang Asif T Chinwalla Pat Minx Makedonka Mitreva Lisa Cook Kim D Delehaunty Catrina Fronick Heather Schmidt Lucinda A Fulton Robert S Fulton Joanne O Nelson Vincent Magrini Craig Pohl Tina A Graves Chris Markovic Andy Cree Huyen H Dinh Jennifer Hume Christie L Kovar Gerald R Fowler Gerton Lunter Stephen Meader Andreas Heger Chris P Ponting Tomas Marques-Bonet Can Alkan Lin Chen Ze Cheng Jeffrey M Kidd Evan E Eichler Simon White Stephen Searle Albert J Vilella Yuan Chen Paul Flicek Jian Ma Brian Raney Bernard Suh Richard Burhans Javier Herrero David Haussler Rui Faria Olga Fernando Fleur Darré Domènec Farré Elodie Gazave Meritxell Oliva Arcadi Navarro Roberta Roberto Oronzo Capozzi Nicoletta Archidiacono Giuliano Della Valle Stefania Purgato Mariano Rocchi Miriam K Konkel Jerilyn A Walker Brygg Ullmer Mark A Batzer Arian F A Smit Robert Hubley Claudio Casola Daniel R Schrider Matthew W Hahn Victor Quesada Xose S Puente Gonzalo R Ordoñez Carlos López-Otín Tomas Vinar Brona Brejova Aakrosh Ratan Robert S Harris Webb Miller Carolin Kosiol Heather A Lawson Vikas Taliwal André L Martins Adam Siepel Arindam Roychoudhury Xin Ma Jeremiah Degenhardt Carlos D Bustamante Ryan N Gutenkunst Thomas Mailund Julien Y Dutheil Asger Hobolth Mikkel H Schierup Oliver A Ryder Yuko Yoshinaga Pieter J de Jong George M Weinstock Jeffrey Rogers Elaine R Mardis Richard A Gibbs Richard K Wilson

Nature 2011 Jan;469(7331):529-33

The Genome Center at Washington University, Washington University School of Medicine, 4444 Forest Park Avenue, Saint Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1038/nature09687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060778PMC
January 2011

Massive turnover of functional sequence in human and other mammalian genomes.

Genome Res 2010 Oct 6;20(10):1335-43. Epub 2010 Aug 6.

MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3QX, United Kingdom.

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http://genome.cshlp.org/cgi/doi/10.1101/gr.108795.110
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http://dx.doi.org/10.1101/gr.108795.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945182PMC
October 2010

Genome assembly quality: assessment and improvement using the neutral indel model.

Genome Res 2010 May 19;20(5):675-84. Epub 2010 Mar 19.

Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3QX, United Kingdom.

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http://dx.doi.org/10.1101/gr.096966.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860169PMC
May 2010