Stephen M Hewitt

Stephen M Hewitt

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Stephen M Hewitt

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Forkhead box protein O1 (FOXO1) and paired box gene 3 (PAX3) overexpression is associated with poor prognosis in patients with cervical cancer.

Int J Clin Oncol 2019 Jul 13. Epub 2019 Jul 13.

Experimental Pathology Laboratory, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/s10147-019-01507-wDOI Listing
July 2019

A mouse model of Proteus syndrome.

Hum Mol Genet 2019 Jun 13. Epub 2019 Jun 13.

Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD, USA.

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http://dx.doi.org/10.1093/hmg/ddz116DOI Listing
June 2019

Immunophenotypic Characterization of Canine Splenic Follicular-Derived B-Cell Lymphoma.

Vet Pathol 2019 05 13;56(3):350-357. Epub 2019 Jan 13.

1 Michigan State University Veterinary Diagnostic Laboratory and Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, MI, USA.

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http://dx.doi.org/10.1177/0300985818823668DOI Listing
May 2019

Combination immunotherapy with IL-4 Pseudomonas exotoxin and IFN-α and IFN-γ mediate antitumor effects in vitro and in a mouse model of human ovarian cancer.

Immunotherapy 2019 Apr;11(6):483-496

Cytokine Biology Section, Division of Intramural Research, National Institute of Allergy & Infectious Diseases, National Institutes of Health, Bethesda, MD 20814, USA.

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http://dx.doi.org/10.2217/imt-2018-0158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439502PMC
April 2019

Data, Information, and Knowledge.

Authors:
Stephen M Hewitt

J Histochem Cytochem 2019 Apr;67(4):227-228

Journal of Histochemistry & Cytochemistry, Truchas, New Mexico.

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http://dx.doi.org/10.1369/0022155419836995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437341PMC
April 2019

Hepatitis B Surface Antigen Activates Unfolded Protein Response in Forming Ground Glass Hepatocytes of Chronic Hepatitis B.

Viruses 2019 Apr 25;11(4). Epub 2019 Apr 25.

Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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https://www.mdpi.com/1999-4915/11/4/386
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http://dx.doi.org/10.3390/v11040386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520809PMC
April 2019

RE: Elevated Bladder Cancer in Northern New England: The Role of Drinking Water and Arsenic.

J Natl Cancer Inst 2018 Nov;110(11):1273-1274

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD.

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http://dx.doi.org/10.1093/jnci/djy045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235686PMC
November 2018

Genomic Network-Based Analysis Reveals Pancreatic Adenocarcinoma Up-Regulating Factor-Related Prognostic Markers in Cervical Carcinoma.

Front Oncol 2018 23;8:465. Epub 2018 Oct 23.

Experimental Pathology Laboratory, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States.

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https://www.frontiersin.org/article/10.3389/fonc.2018.00465/
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http://dx.doi.org/10.3389/fonc.2018.00465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206228PMC
October 2018

Elevated expression of pancreatic adenocarcinoma upregulated factor (PAUF) is associated with poor prognosis and chemoresistance in epithelial ovarian cancer.

Sci Rep 2018 Aug 15;8(1):12161. Epub 2018 Aug 15.

Experimental Pathology Laboratory, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1038/s41598-018-30582-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093878PMC
August 2018

Targeting Cyclin D-CDK4/6 Sensitizes Immune-Refractory Cancer by Blocking the SCP3-NANOG Axis.

Cancer Res 2018 05 6;78(10):2638-2653. Epub 2018 Feb 6.

Laboratory of Tumor Immunology, Department of Biomedical Sciences, Graduate School of Medicine, Korea University, Seoul, Korea.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-2325DOI Listing
May 2018

Reproducibility and Feasibility of Strategies for Morphologic Assessment of Renal Biopsies Using the Nephrotic Syndrome Study Network Digital Pathology Scoring System.

Arch Pathol Lab Med 2018 May 19;142(5):613-625. Epub 2018 Feb 19.

From Biostatistics, Arbor Research Collaborative for Health, Ann Arbor, Michigan (Dr Zee); the Departments of Pathology (Dr Hodgin), Internal Medicine (Dr Mariani), and Biostatistics (Dr Gillespie), University of Michigan, Ann Arbor; Arbor Research Collaborative for Health, Ann Arbor, Michigan (Dr Mariani); the Department of Pathology & Immunology, Washington University, St Louis, Missouri (Dr Gaut); the Departments of Pathology and Laboratory Medicine (Dr Palmer) and Medicine (Dr. Holzman), University of Pennsylvania, Philadelphia; the Department of Pathology, Johns Hopkins University, Baltimore, Maryland (Drs Bagnasco and Rosenberg); the Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland (Dr Rosenberg); the Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland (Dr Hewitt); and the Department of Pathology, University of Miami, Miami, Florida (Dr Barisoni).

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http://dx.doi.org/10.5858/arpa.2017-0181-OADOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946059PMC
May 2018

The Role of Extracellular Matrix in Innate Immunity, Fugues of Evolution.

Authors:
Stephen M Hewitt

J Histochem Cytochem 2018 04 14;66(4):211. Epub 2018 Feb 14.

Journal of Histochemistry & Cytochemistry, Truchas, New Mexico.

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http://dx.doi.org/10.1369/0022155418761352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958382PMC
April 2018

Histomorphological and Molecular Assessments of the Fixation Times Comparing Formalin and Ethanol-Based Fixatives.

J Histochem Cytochem 2018 02 10;66(2):121-135. Epub 2017 Nov 10.

Experimental Pathology Laboratory, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1369/0022155417741467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794201PMC
February 2018

Nonalcoholic fatty liver disease in spinal and bulbar muscular atrophy.

Neurology 2017 Dec 15;89(24):2481-2490. Epub 2017 Nov 15.

From the Neurogenetics Branch (R.D.G., A.K., D.A.F., I.K., D.B., K.H.F., C.G.), National Institute of Neurological Disorders and Stroke; Liver Diseases Branch (V.T., H.A., Y.R.), National Institute of Diabetes and Digestive and Kidney Diseases; Cardiovascular and Pulmonary Branch (A.T.R.), National Heart Lung & Blood Institute; Laboratory of Pathology (S.M.H., D.E.K.), National Cancer Institute; Radiology and Imaging Sciences (C.-Y.L.), Clinical Center, National Institute of Allergy and Infectious Diseases; and NIH (C.H.), Bethesda, MD.

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http://dx.doi.org/10.1212/WNL.0000000000004748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729799PMC
December 2017

HDAC1 Upregulation by NANOG Promotes Multidrug Resistance and a Stem-like Phenotype in Immune Edited Tumor Cells.

Cancer Res 2017 09 17;77(18):5039-5053. Epub 2017 Jul 17.

Laboratory of Tumor Immunology, Department of Biomedical Sciences, Graduate School of Medicine, Korea University, Seoul, Korea.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-0072DOI Listing
September 2017

Bcl-2-like Protein 11 (BIM) Expression Is Associated with Favorable Prognosis for Patients with Cervical Cancer.

Anticancer Res 2017 09;37(9):4873-4879

Department of Obstetrics and Gynecology, Gangnam Severance Hospital, College of Medicine, Yonsei University, Seoul, Republic of Korea

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http://dx.doi.org/10.21873/anticanres.11896DOI Listing
September 2017

Therapeutically targeting glypican-2 via single-domain antibody-based chimeric antigen receptors and immunotoxins in neuroblastoma.

Proc Natl Acad Sci U S A 2017 08 24;114(32):E6623-E6631. Epub 2017 Jul 24.

Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892;

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http://dx.doi.org/10.1073/pnas.1706055114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559039PMC
August 2017

The Impact Factor Is a 20th-Century Relic in an Electronic Journal World of Instant Citation Counts.

Authors:
Stephen M Hewitt

J Histochem Cytochem 2017 07;65(7):387-388

National Cancer Institute, National Institutes of Health, Bethesda, Maryland (SMH).

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http://dx.doi.org/10.1369/0022155417712485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490849PMC
July 2017

Expression of the scaffold connector enhancer of kinase suppressor of Ras 1 (CNKSR1) is correlated with clinical outcome in pancreatic cancer.

BMC Cancer 2017 Jul 21;17(1):495. Epub 2017 Jul 21.

Thoracic and Gastrointestinal Oncology Branch, Gastrointestinal Oncology Section, Investigator Center for Cancer Research, National Cancer Institute, Building 10 - Hatfield CRC, Room 4-5950, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1186/s12885-017-3481-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522593PMC
July 2017

The anti-cancer effects of itraconazole in epithelial ovarian cancer.

Sci Rep 2017 07 26;7(1):6552. Epub 2017 Jul 26.

Departments of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1038/s41598-017-06510-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529373PMC
July 2017

The paraffin-embedded RNA metric (PERM) for RNA isolated from formalin-fixed, paraffin-embedded tissue.

Biotechniques 2016 1;60(5):239-44. Epub 2016 May 1.

Experimental Pathology Laboratory, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.2144/000114415DOI Listing
June 2017

Synaptonemal complex protein 3 is associated with lymphangiogenesis in non-small cell lung cancer patients with lymph node metastasis.

J Transl Med 2017 06 17;15(1):138. Epub 2017 Jun 17.

Experimental Pathology Laboratory, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1186/s12967-017-1241-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473978PMC
June 2017

PAX3-FOXO1 is essential for tumour initiation and maintenance but not recurrence in a human myoblast model of rhabdomyosarcoma.

J Pathol 2017 04 1;241(5):626-637. Epub 2017 Mar 1.

Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1002/path.4867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357165PMC
April 2017

Multiview boosting digital pathology analysis of prostate cancer.

Comput Methods Programs Biomed 2017 Apr 22;142:91-99. Epub 2017 Feb 22.

Tissue Array Research Program, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, MD 20852, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01692607163069
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http://dx.doi.org/10.1016/j.cmpb.2017.02.023DOI Listing
April 2017

Editor's Note.

Authors:
Stephen M Hewitt

J Histochem Cytochem 2017 04;65(4):254

National Cancer Institute, National Institutes of Health, Bethesda, Maryland (SMH).

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http://dx.doi.org/10.1369/0022155416688260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407562PMC
April 2017

Formulation and pH of the Buffered Ethanol Fixative BE70.

Authors:
Stephen M Hewitt

J Histochem Cytochem 2017 04;65(4):251-252

National Cancer Institute, National Institutes of Health, Bethesda, Maryland (SMH).

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http://dx.doi.org/10.1369/0022155416687279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407559PMC
April 2017

Computational analysis of the mesenchymal signature landscape in gliomas.

BMC Med Genomics 2017 03 9;10(1):13. Epub 2017 Mar 9.

Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, 10 Center Drive, Bldg. 10, Rm. B3B70, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1186/s12920-017-0252-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345226PMC
March 2017

Molecular Chaperone HSP90 Is Necessary to Prevent Cellular Senescence via Lysosomal Degradation of p14ARF.

Cancer Res 2017 01 28;77(2):343-354. Epub 2016 Oct 28.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea (South).

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http://dx.doi.org/10.1158/0008-5472.CAN-16-0613DOI Listing
January 2017

A melanin-bleaching methodology for molecular and histopathological analysis of formalin-fixed paraffin-embedded tissue.

Lab Invest 2016 10 22;96(10):1116-27. Epub 2016 Aug 22.

Experimental Pathology Laboratory, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/labinvest.2016.90DOI Listing
October 2016

Risk of follicular lymphoma associated with BCL2 translocations in peripheral blood.

Leuk Lymphoma 2015 17;56(9):2625-9. Epub 2015 Mar 17.

b Division of Cancer Epidemiology and Genetics, National Cancer Institute , Bethesda , MD , USA.

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http://dx.doi.org/10.3109/10428194.2014.999324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819878PMC
August 2016

Targeting a Cancer-Specific Epitope of the Epidermal Growth Factor Receptor in Triple-Negative Breast Cancer.

J Natl Cancer Inst 2016 08 13;108(8). Epub 2016 Apr 13.

Affiliations of authors: Biotherapy Section, Laboratory of Molecular Biology (NS, AA, RS, DF), and Experimental Pathology Laboratory, Laboratory of Pathology (SMH), Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1093/jnci/djw028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017938PMC
August 2016

Prognostic Significance of AMP-Dependent Kinase Alpha Expression in Cervical Cancer.

Pathobiology 2015 25;82(5):203-11. Epub 2015 Aug 25.

Experimental Pathology Laboratory, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Md., USA.

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https://www.karger.com/Article/FullText/434726
Publisher Site
http://dx.doi.org/10.1159/000434726DOI Listing
July 2016

A Buffered Alcohol-Based Fixative for Histomorphologic and Molecular Applications.

J Histochem Cytochem 2016 07 24;64(7):425-40. Epub 2016 May 24.

Experimental Pathology Laboratory, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland (CP, J-YC, KY, CHC, AS, KTM, WAS, SMH)

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http://journals.sagepub.com/doi/10.1369/0022155416649579
Publisher Site
http://dx.doi.org/10.1369/0022155416649579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931761PMC
July 2016

Prognostic significance of annexin A2 and annexin A4 expression in patients with cervical cancer.

BMC Cancer 2016 07 11;16:448. Epub 2016 Jul 11.

Experimental Pathology Laboratory, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, MSC 1500, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1186/s12885-016-2459-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940752PMC
July 2016

Automated prostate tissue referencing for cancer detection and diagnosis.

BMC Bioinformatics 2016 Jun 1;17(1):227. Epub 2016 Jun 1.

Beckman Institute for Advanced Science and Technology, Department of Bioengineering, Department of Mechanical Science and Engineering, Electrical and Computer Engineering, Chemical and Biomolecular Engineering and University of Illinois Cancer Center, University of Illinois at Urbana-Champaign, 4265 Beckman Institute 405 N. Mathews Avenue, Urbana, IL, 61801, USA.

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http://dx.doi.org/10.1186/s12859-016-1086-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888626PMC
June 2016

Decreased Expression of Retinoid X Receptors During Human and Azoxymethane-induced Colorectal Carcinogenesis in the Rat.

Anticancer Res 2016 Jun;36(6):2659-64

Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, Rockville, MD, U.S.A.

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June 2016

Expression of fibroblast growth factor receptor family members is associated with prognosis in early stage cervical cancer patients.

J Transl Med 2016 05 6;14(1):124. Epub 2016 May 6.

Experimental Pathology Laboratory, Laboratory of Pathology, National Cancer Institute, Center for Cancer Research, National Institutes of Health, MSC 1500, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1186/s12967-016-0874-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859953PMC
May 2016

Reproducibility: It Is Just Good Science.

Authors:
Stephen M Hewitt

J Histochem Cytochem 2016 Apr;64(4):223

Journal of Histochemistry & Cytochemistry, Truchas, New Mexico (SMH)

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http://dx.doi.org/10.1369/0022155416636547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817731PMC
April 2016

A well-based reverse-phase protein array of formalin-fixed paraffin-embedded tissue.

Methods Mol Biol 2015 ;1312:129-39

Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, MSC 1500, Bethesda, Maryland, MD, 20892, USA.

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http://dx.doi.org/10.1007/978-1-4939-2694-7_17DOI Listing
February 2016

Proteomic expressional profiling of a paraffin-embedded tissue by multiplex tissue immunoblotting.

Methods Mol Biol 2015 ;1312:175-84

Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, MSC 1500, Bethesda, Maryland, MD, 20892, USA.

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http://dx.doi.org/10.1007/978-1-4939-2694-7_21DOI Listing
February 2016

Time Advances, People and Language Change, but the Fundamentals Remain the Same.

Authors:
Stephen M Hewitt

J Histochem Cytochem 2016 Jan;64(1):5-6

Journal of Histochemistry and Cytochemistry, Truchas, New Mexico, USA (SMH)

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http://dx.doi.org/10.1369/0022155415617744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810795PMC
January 2016

The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl.

Breast Cancer Res Treat 2016 Jan 12;155(2):235-51. Epub 2016 Jan 12.

Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 10, Room 4B54, Bethesda, MD, USA.

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http://dx.doi.org/10.1007/s10549-015-3673-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753803PMC
January 2016

A Novel Quantitative Multiplex Tissue Immunoblotting for Biomarkers Predicts a Prostate Cancer Aggressive Phenotype.

Cancer Epidemiol Biomarkers Prev 2015 Dec 24;24(12):1864-72. Epub 2015 Sep 24.

The James Buchanan Brady Urological Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1158/1055-9965.EPI-15-0496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755280PMC
December 2015

Clinical significance of OCT4 and SOX2 protein expression in cervical cancer.

BMC Cancer 2015 Dec 26;15:1015. Epub 2015 Dec 26.

Experimental Pathology Lab, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, MSC 1500, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1186/s12885-015-2015-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691290PMC
December 2015

CDK4 Amplification Reduces Sensitivity to CDK4/6 Inhibition in Fusion-Positive Rhabdomyosarcoma.

Clin Cancer Res 2015 Nov 25;21(21):4947-59. Epub 2015 Mar 25.

Cancer Molecular Pathology Section, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583342PMC
November 2015

Modification of Occupational Exposures on Bladder Cancer Risk by Common Genetic Polymorphisms.

J Natl Cancer Inst 2015 Nov 14;107(11). Epub 2015 Sep 14.

Division of Cancer Epidemiology and Genetics (JDF, SK, JSC, MGC, MCF, DB, PS, LEM, LPO, ARB, AP, JFFJr, SJC, NC, NR, DTS), Experimental Pathology Laboratory, Laboratory of Pathology, Center for Cancer Research (KY, JYC, SMH), and Cancer and Inflammation Program (MLN), National Cancer Institute, Bethesda, MD; Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh Medical School, Edinburgh UK (JDF); CIBERESP, CIBER Epidemiologia y Salud Publica, Madrid, Spain (MK, AT, JL); Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain (MK); Municipal Institute of Medical Research (IMIM-Hospital del Mar), Barcelona, Spain (MK); Division of Genetics and Epidemiology, Institute of Cancer Research, London, UK (MGC); Spanish National Cancer Research Centre (CNIO), Madrid, Spain (FXR, NM); Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain (FXR, CS); Maine Cancer Registry, Augusta, ME (MS); Vermont Cancer Registry, Burlington, VT (AJ); Geisel School of Medicine at Dartmouth, Hanover, NH (MRK, AS); New Hampshire Department of Health and Human Services, Concord, NH (KRA); Clinical Research Directorate/Clinical Monitoring Research Program, Leidos Biomedical Research, Inc. (formerly SAIC-Frederick, Inc.), Frederick National Laboratory for Cancer Research, Frederick, MD (PL); Molecular Epidemiology Group, Instituto Universitario de Oncologia, Universidad de Oviedo, Oviedo, Asturias, Spain (AT); Hospital Ramón y Cajal, Elche, Madrid, Spain (AC); Unidad de Investigación, Hospital Universitario de Canarias, La Laguna, Spain (RGC).

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http://dx.doi.org/10.1093/jnci/djv223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675099PMC
November 2015

Efficacy of Intralesional Botulinum Toxin A for Treatment of Painful Cutaneous Leiomyomas: A Randomized Clinical Trial.

JAMA Dermatol 2015 Oct;151(10):1096-102

Dermatology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.

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http://dx.doi.org/10.1001/jamadermatol.2015.1793DOI Listing
October 2015

PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis.

Nat Commun 2015 Jul 17;6:7769. Epub 2015 Jul 17.

Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea.

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http://dx.doi.org/10.1038/ncomms8769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518267PMC
July 2015

The evolution of pre-analytic factors in Anatomic Pathology.

Authors:
Stephen M Hewitt

Recent Results Cancer Res 2015 ;199:27-34

Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 10 Center Drive, MSC 1500, Bethesda, MD, 20892, USA,

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http://dx.doi.org/10.1007/978-3-319-13957-9_3DOI Listing
June 2015

Pancreatic adenocarcinoma up-regulated factor expression is associated with disease-specific survival in cervical cancer patients.

Hum Pathol 2015 Jun 11;46(6):884-93. Epub 2015 Mar 11.

Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2015.02.016DOI Listing
June 2015

A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis.

Nat Genet 2015 Jun 11;47(6):615-24. Epub 2015 May 11.

1] Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA. [2] Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota, USA. [3] Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA. [4] Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota, USA.

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http://dx.doi.org/10.1038/ng.3293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767150PMC
June 2015

Molecular transitions from papillomavirus infection to cervical precancer and cancer: Role of stromal estrogen receptor signaling.

Proc Natl Acad Sci U S A 2015 Jun 8;112(25):E3255-64. Epub 2015 Jun 8.

Morgridge Institute for Research, University of Wisconsin-Madison, Madison, WI 53715; McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, WI 53792; Institute for Molecular Virology, University of Wisconsin-Madison, Madison, WI 53706; Howard Hughes Medical Institute, University of Wisconsin-Madison, Madison, WI 53706;

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http://dx.doi.org/10.1073/pnas.1509322112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485108PMC
June 2015

Evaluating whole slide imaging: A working group opportunity.

J Pathol Inform 2015 24;6. Epub 2015 Feb 24.

Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355829PMC
March 2015

Stain-less staining for computed histopathology.

Technology (Singap World Sci) 2015 Mar;3(1):27-31

Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. ; Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801 and Carle Foundation Hospital, Urbana, IL 61801, USA. ; Departments of Mechanical Science and Engineering, Electrical and Computer Engineering, Chemical and Biomolecular Engineering and Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

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http://dx.doi.org/10.1142/S2339547815200010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445956PMC
March 2015

Cell-cycle protein expression in a population-based study of ovarian and endometrial cancers.

Front Oncol 2015 9;5:25. Epub 2015 Feb 9.

Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health , Bethesda, MD , USA.

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http://dx.doi.org/10.3389/fonc.2015.00025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321403PMC
February 2015

Greater absolute risk for all subtypes of breast cancer in the US than Malaysia.

Breast Cancer Res Treat 2015 Jan 24;149(1):285-91. Epub 2014 Dec 24.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA.

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http://dx.doi.org/10.1007/s10549-014-3243-9DOI Listing
January 2015

MICA/B and ULBP1 NKG2D ligands are independent predictors of good prognosis in cervical cancer.

BMC Cancer 2014 Dec 15;14:957. Epub 2014 Dec 15.

Department of Obstetrics and Gynecology, Gangnam Severance Hospital, Yonsei University College of Medicine, 146-92 Dogok-Dong, Gangnam-Gu, Seoul 135-720, Korea.

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http://dx.doi.org/10.1186/1471-2407-14-957DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301905PMC
December 2014

The 19q12 bladder cancer GWAS signal: association with cyclin E function and aggressive disease.

Authors:
Yi-Ping Fu Indu Kohaar Lee E Moore Petra Lenz Jonine D Figueroa Wei Tang Patricia Porter-Gill Nilanjan Chatterjee Alexandra Scott-Johnson Montserrat Garcia-Closas Brian Muchmore Dalsu Baris Ashley Paquin Kris Ylaya Molly Schwenn Andrea B Apolo Margaret R Karagas McAnthony Tarway Alison Johnson Adam Mumy Alan Schned Liliana Guedez Michael A Jones Masatoshi Kida G M Monawar Hosain Nuria Malats Manolis Kogevinas Adonina Tardon Consol Serra Alfredo Carrato Reina Garcia-Closas Josep Lloreta Xifeng Wu Mark Purdue Gerald L Andriole Robert L Grubb Amanda Black Maria T Landi Neil E Caporaso Paolo Vineis Afshan Siddiq H Bas Bueno-de-Mesquita Dimitrios Trichopoulos Börje Ljungberg Gianluca Severi Elisabete Weiderpass Vittorio Krogh Miren Dorronsoro Ruth C Travis Anne Tjønneland Paul Brennan Jenny Chang-Claude Elio Riboli Jennifer Prescott Constance Chen Immaculata De Vivo Edward Govannucci David Hunter Peter Kraft Sara Lindstrom Susan M Gapstur Eric J Jacobs W Ryan Diver Demetrius Albanes Stephanie J Weinstein Jarmo Virtamo Charles Kooperberg Chancellor Hohensee Rebecca J Rodabough Victoria K Cortessis David V Conti Manuela Gago-Dominguez Mariana C Stern Malcolm C Pike David Van Den Berg Jian-Min Yuan Christopher A Haiman Olivier Cussenot Geraldine Cancel-Tassin Morgan Roupret Eva Comperat Stefano Porru Angela Carta Sofia Pavanello Cecilia Arici Giuseppe Mastrangelo H Barton Grossman Zhaoming Wang Xiang Deng Charles C Chung Amy Hutchinson Laurie Burdette William Wheeler Joseph Fraumeni Stephen J Chanock Stephen M Hewitt Debra T Silverman Nathaniel Rothman Ludmila Prokunina-Olsson

Cancer Res 2014 Oct;74(20):5808-18

Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-1531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203382PMC
October 2014

Evaluation environment for digital and analog pathology: a platform for validation studies.

J Med Imaging (Bellingham) 2014 Oct 12;1(3):037501. Epub 2014 Nov 12.

National Cancer Institute , National Institutes of Health, Center for Cancer Research, Laboratory of Pathology, 10 Center Drive, MSC 1500, Bethesda, Maryland 20892, United States.

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http://dx.doi.org/10.1117/1.JMI.1.3.037501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478997PMC
October 2014

Multiple chimeric antigen receptors successfully target chondroitin sulfate proteoglycan 4 in several different cancer histologies and cancer stem cells.

J Immunother Cancer 2014 19;2:25. Epub 2014 Aug 19.

Surgery Branch, Center for Cancer Research, National Cancer Institute, 10 Center Drive, Building 10 Hatfield CRC, Rm 3-5930, 20892-1201 Bethesda, MD, USA ; Current address: Bluebird bio, 150 Second St, Cambridge, MA 02141, USA.

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http://dx.doi.org/10.1186/2051-1426-2-25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155770PMC
September 2014