Publications by authors named "Stephen M Beverley"

139Publications

Mannogen-ing Central Carbon Metabolism by Leishmania.

Trends Parasitol 2019 12 26;35(12):947-949. Epub 2019 Oct 26.

Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO 63110, USA. Electronic address:

View Article and Find Full Text PDF
December 2019

Whole genome sequencing of experimental hybrids supports meiosis-like sexual recombination in Leishmania.

PLoS Genet 2019 05 15;15(5):e1008042. Epub 2019 May 15.

Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.

View Article and Find Full Text PDF
May 2019

Leishmania Lipophosphoglycan Triggers Caspase-11 and the Non-canonical Activation of the NLRP3 Inflammasome.

Cell Rep 2019 01;26(2):429-437.e5

Departamento de Biologia Celular e Molecular e Bioagentes Patogênicos, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, São Paulo, Brazil. Electronic address:

View Article and Find Full Text PDF
January 2019

TLR2 Signaling in Skin Nonhematopoietic Cells Induces Early Neutrophil Recruitment in Response to Leishmania major Infection.

J Invest Dermatol 2019 06 27;139(6):1318-1328. Epub 2018 Dec 27.

Department of Biochemistry, Faculty of Biology and Medicine, University of Lausanne, Epalinges, Switzerland; World Health Organization Immunology Research and Training Center, Faculty of Biology and Medicine, University of Lausanne, Epalinges, Switzerland. Electronic address:

View Article and Find Full Text PDF
June 2019

SODB1 is essential for Leishmania major infection of macrophages and pathogenesis in mice.

PLoS Negl Trop Dis 2018 10 29;12(10):e0006921. Epub 2018 Oct 29.

Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America.

View Article and Find Full Text PDF
October 2018

Importance of polyphosphate in the life cycle.

Microb Cell 2018 Jun 22;5(8):371-384. Epub 2018 Jun 22.

Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.

View Article and Find Full Text PDF
June 2018

Concentration of 2'C-methyladenosine triphosphate by enables specific inhibition of RNA virus 1 via its RNA polymerase.

J Biol Chem 2018 04 6;293(17):6460-6469. Epub 2018 Mar 6.

From the Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110

View Article and Find Full Text PDF
April 2018

Spontaneous excision and facilitated recovery as a control for phenotypes arising from RNA interference and other dominant transgenes.

Mol Biochem Parasitol 2018 03 3;220:42-45. Epub 2018 Feb 3.

Department of Molecular Microbiology, Washington University School of Medicine, 660 S. Euclid Ave, Campus Box 8230, St. Louis, MO 63110, United States. Electronic address:

View Article and Find Full Text PDF
March 2018

Development of a semi-automated image-based high-throughput drug screening system.

Front Biosci (Elite Ed) 2018 Jan 1;10:242-253. Epub 2018 Jan 1.

Department of Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland,

View Article and Find Full Text PDF
January 2018

Gene Expression in Is Regulated Predominantly by Gene Dosage.

mBio 2017 09 12;8(5). Epub 2017 Sep 12.

Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA

View Article and Find Full Text PDF
September 2017

Genetic metabolic complementation establishes a requirement for GDP-fucose in .

J Biol Chem 2017 06 2;292(25):10696-10708. Epub 2017 May 2.

From the Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110,

View Article and Find Full Text PDF
June 2017

The Evolutionary Loss of RNAi Key Determinants in Kinetoplastids as a Multiple Sporadic Phenomenon.

J Mol Evol 2017 03 16;84(2-3):104-115. Epub 2017 Feb 16.

Department of Microbiology and Immunology and the Center for the Study of Biological Complexity, Virginia Commonwealth University, Richmond, VA, USA.

View Article and Find Full Text PDF
March 2017

Antiviral screening identifies adenosine analogs targeting the endogenous dsRNA Leishmania RNA virus 1 (LRV1) pathogenicity factor.

Proc Natl Acad Sci U S A 2017 01 17;114(5):E811-E819. Epub 2017 Jan 17.

Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110;

View Article and Find Full Text PDF
January 2017

Continual renewal and replication of persistent Leishmania major parasites in concomitantly immune hosts.

Proc Natl Acad Sci U S A 2017 01 17;114(5):E801-E810. Epub 2017 Jan 17.

Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110

View Article and Find Full Text PDF
January 2017