Stephen Lynch

Stephen Lynch

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Stephen Lynch

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Stem cell models as an model for predictive toxicology.

Biochem J 2019 Apr 15;476(7):1149-1158. Epub 2019 Apr 15.

Department of Molecular and Clinical Pharmacology, MRC Centre for Drug Safety Science, University of Liverpool, Sherrington Building, Ashton Street, Liverpool L69 3GE, U.K.

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http://dx.doi.org/10.1042/BCJ20170780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463389PMC
April 2019

Weight-based tacrolimus trough concentrations post liver transplant.

Intern Med J 2019 Jan;49(1):79-83

School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia.

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http://dx.doi.org/10.1111/imj.14043DOI Listing
January 2019

Dynamics and Microstructures of Nicotine/Water Binary Mixtures near the Lower Critical Solution Temperature.

J Phys Chem B 2018 10 3;122(41):9538-9548. Epub 2018 Oct 3.

Department of Chemistry , Stanford University , Stanford , California 94305 , United States.

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http://dx.doi.org/10.1021/acs.jpcb.8b06205DOI Listing
October 2018

An Alkaloid from Scorpion Venom: Chemical Structure and Synthesis.

J Nat Prod 2018 08 20;81(8):1899-1904. Epub 2018 Jul 20.

Department of Chemistry , Stanford University , Stanford , California 94305 , United States.

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http://dx.doi.org/10.1021/acs.jnatprod.8b00527DOI Listing
August 2018

Adolescent tracheal intubation in an adult urban emergency department: a retrospective, observational study.

Eur J Emerg Med 2017 Dec;24(6):e6-e10

aDepartment of Anaesthesia, Pain and Critical Care, Western General Hospital bDepartment of Emergency Medicine, Anaesthesia and Critical Care, Royal Infirmary of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1097/MEJ.0000000000000398DOI Listing
December 2017

Bilateral Testicular Infarction from IgA Vasculitis of the Spermatic Cords.

Case Rep Nephrol 2017 21;2017:9437965. Epub 2017 Nov 21.

Division of Nephrology, Department of Internal Medicine, Beaumont Health, Royal Oak, MI, USA.

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http://dx.doi.org/10.1155/2017/9437965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735612PMC
November 2017

Surface Zeta Potential and Diamond Seeding on Gallium Nitride Films.

ACS Omega 2017 Oct 27;2(10):7275-7280. Epub 2017 Oct 27.

School of Physics and Astronomy and School of Engineering, Cardiff University, Cardiff CF24 3AA, U.K.

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http://dx.doi.org/10.1021/acsomega.7b01069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645065PMC
October 2017

Partial In Vitro Reconstitution of an Orphan Polyketide Synthase Associated with Clinical Cases of Nocardiosis.

ACS Chem Biol 2016 09 5;11(9):2636-41. Epub 2016 Aug 5.

Department of Chemical Engineering, ‡Department of Chemistry, §Stanford Magnetic Resonance Laboratory, and ∥Stanford ChEM-H, Stanford University , Stanford, California 94305, United States.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055052PMC
http://dx.doi.org/10.1021/acschembio.6b00489DOI Listing
September 2016

Structure and thermodynamics of N6-methyladenosine in RNA: a spring-loaded base modification.

J Am Chem Soc 2015 Feb 2;137(5):2107-15. Epub 2015 Feb 2.

Department of Chemistry, ‡Howard Hughes Medical Institute and Program in Epithelial Biology, Stanford University , Stanford, California 94305, United States.

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http://dx.doi.org/10.1021/ja513080vDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405242PMC
February 2015

In TCR-stimulated T-cells, N-ras regulates specific genes and signal transduction pathways.

PLoS One 2014 3;8(6):e63193. Epub 2013 Jun 3.

Department of Pathology, New York University Langone School of Medicine, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063193PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670928PMC
January 2015

N-Aryl azacycles as novel sodium channel blockers.

Bioorg Med Chem Lett 2015 Jan 14;25(1):48-52. Epub 2014 Nov 14.

Discovery Research, Purdue Pharma L.P., 6 Cedarbrook Drive, Cranbury, NJ 08512, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S0960894X140120
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http://dx.doi.org/10.1016/j.bmcl.2014.11.023DOI Listing
January 2015

Dibenzazepines and dibenzoxazepines as sodium channel blockers.

Bioorg Med Chem Lett 2015 Jan 14;25(1):43-7. Epub 2014 Nov 14.

Discovery Research, Purdue Pharma LP, 6 Cedarbrook Drive, Cranbury, NJ 08512, United States.

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http://dx.doi.org/10.1016/j.bmcl.2014.11.025DOI Listing
January 2015

Quantifying the pattern of microbial cell dispersion, density and clustering on surfaces of differing chemistries and topographies using multifractal analysis.

J Microbiol Methods 2014 Sep 9;104:101-8. Epub 2014 Jul 9.

School of Healthcare Science, Manchester Metropolitan University, Chester St, Manchester M1 5GD, UK; Surface Engineering Group, Manchester Metropolitan University, Chester St, Manchester M1 5GD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.mimet.2014.07.005DOI Listing
September 2014

Donor-transmitted, donor-derived, and de novo cancer after liver transplant.

Exp Clin Transplant 2014 Mar;12 Suppl 1:50-4

Centre for Transplant and Renal Research, Westmead Millennium Institute, University of Sydney, Sydney, New South Wales, Australia.

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March 2014

Intracellular matrix metalloproteinase-2 (MMP-2) regulates human platelet activation via hydrolysis of talin.

Thromb Haemost 2014 Jan 17;111(1):140-53. Epub 2013 Oct 17.

Gerald Soslau, PhD, Office of Professional Studies in the Health Sciences, Drexel University College of Medicine, 245 N 15th Street, Philadelphia, PA 19102, USA, Tel.: +1 215 762 7831, Fax: +1 215 762 7434, E-mail:

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http://dx.doi.org/10.1160/TH13-03-0248DOI Listing
January 2014

Estimating the horizontal and vertical direction-of-arrival of water-borne seismic signals in the northern Philippine Sea.

J Acoust Soc Am 2013 Oct;134(4):3282-98

Marine Physical Laboratory, Scripps Institution of Oceanography, 291 Rosecrans Street, University of California San Diego, Scripps Institution of Oceanography, Marine Physical Laboratory Building 4, San Diego, California 92106.

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http://dx.doi.org/10.1121/1.4818843DOI Listing
October 2013

Surgical implications of a left-sided gallbladder.

Am J Surg 2013 Jul 20;206(1):59-63. Epub 2013 Feb 20.

Hepatobiliary Unit, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Queensland 4102, Australia.

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http://dx.doi.org/10.1016/j.amjsurg.2012.10.035DOI Listing
July 2013

Discovery of a series of novel 5H-pyrrolo[2,3-b]pyrazine-2-phenyl ethers, as potent JAK3 kinase inhibitors.

Bioorg Med Chem Lett 2013 May 14;23(9):2522-6. Epub 2013 Mar 14.

Hoffmann-La Roche Inc., pRED, Pharma Research & Early Development, Small Molecule Research, Discovery Chemistry, 340 Kingsland Street, Nutley, NJ 07110-1199, USA.

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http://dx.doi.org/10.1016/j.bmcl.2013.03.015DOI Listing
May 2013

Iron levels found in hemochromatosis patients inhibit γ-thrombin-induced platelet aggregation.

Platelets 2012 23;23(8):611-6. Epub 2011 Nov 23.

Office of Professional Studies in the Health Sciences, Drexel University College of Medicine, Philadelphia, PA 19102, USA.

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http://dx.doi.org/10.3109/09537104.2011.634933DOI Listing
April 2013

Oscillatory threshold logic.

PLoS One 2012 16;7(11):e48498. Epub 2012 Nov 16.

School of Computing, Mathematics and Digital Technology, Manchester Metropolitan University, Manchester, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0048498PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500268PMC
March 2013

Antimicrobial activity of nanocomposite zirconium nitride/silver coatings to combat external bone fixation pin infections.

Int J Artif Organs 2012 Oct;35(10):817-25

School of Healthcare Sciences, Manchester Metropolitan University, Manchester, UK.

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http://journals.sagepub.com/doi/10.5301/ijao.5000156
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http://dx.doi.org/10.5301/ijao.5000156DOI Listing
October 2012

Fast dynamics of HP35 for folded and urea-unfolded conditions.

J Phys Chem B 2012 Sep 29;116(36):11024-31. Epub 2012 Aug 29.

Department of Chemistry, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1021/jp304058xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475495PMC
September 2012

Evidence of Doppler-shifted Bragg scattering in the vertical plane by ocean surface waves.

J Acoust Soc Am 2012 Mar;131(3):2011-22

Marine Physical Laboratory, Scripps Institution of Oceanography, La Jolla, California 92093-0701, USA.

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http://dx.doi.org/10.1121/1.3683247DOI Listing
March 2012

Orientational and translational dynamics of polyether/water solutions.

J Phys Chem B 2010 Apr;114(16):5350-8

Department of Chemistry, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1021/jp101369eDOI Listing
April 2010

Structure and replication of yDNA: a novel genetic set widened by benzo-homologation.

Chembiochem 2009 Oct;10(15):2530-8

Department of Chemistry, Stanford University, Stanford, CA 94305-5080, USA.

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http://dx.doi.org/10.1002/cbic.200900434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982676PMC
October 2009

Long-term results of liver resection for non-colorectal, non-neuroendocrine metastases.

Ann Surg Oncol 2008 Jan 26;15(1):207-18. Epub 2007 Oct 26.

Department of Hepatobiliary Surgery, Basingstoke and North Hampshire Foundation Trust, Basingstoke, United Kingdom.

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http://dx.doi.org/10.1245/s10434-007-9649-4DOI Listing
January 2008

Undetected hepatocellular carcinoma in patients undergoing liver transplantation: is associated with favorable outcome.

Hepatogastroenterology 2007 Jun;54(76):1192-5

Queensland Liver Transplant Service, Princess Alexandra Hospital, Brisbane, Australia.

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June 2007

Active control of passive acoustic fields: passive synthetic aperture/Doppler beamforming with data from an autonomous vehicle.

J Acoust Soc Am 2006 Dec;120(6):3635-54

Marine Physical Laboratory, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 93940-0701, USA.

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http://dx.doi.org/10.1121/1.2346177DOI Listing
December 2006

Measurement and stability of FTY720 in human whole blood by high-performance liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2006 Nov 16;843(2):157-63. Epub 2006 Jun 16.

Australian Bioanalytical Services Pty Ltd., Princess Alexandra Hospital, Brisbane, Queensland 4102, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S157002320600449
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http://dx.doi.org/10.1016/j.jchromb.2006.05.026DOI Listing
November 2006

Toward a designed, functioning genetic system with expanded-size base pairs: solution structure of the eight-base xDNA double helix.

J Am Chem Soc 2006 Nov;128(45):14704-11

Department of Chemistry, Stanford University, Stanford, California 94305-5080, USA.

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http://dx.doi.org/10.1021/ja065606nDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519095PMC
November 2006

Kaposi's Sarcoma-associated herpesvirus lytic switch protein stimulates DNA binding of RBP-Jk/CSL to activate the Notch pathway.

J Virol 2006 Oct;80(19):9697-709

Department of Microbiology and Molecular Genetics, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07101, USA.

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http://dx.doi.org/10.1128/JVI.00746-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1617261PMC
October 2006

Molecular pharmacology and antitumor activity of palmarumycin-based inhibitors of thioredoxin reductase.

Mol Cancer Ther 2006 Mar;5(3):630-6

Department of Experimental Therapeutics, M.D. Anderson Cancer Center, FC-6.3044, 1515 Holcombe Boulevard, Houston, TX 77030-4009, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-05-0487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462925PMC
March 2006

Living donor liver transplantation--adult donor outcomes: a systematic review.

Liver Transpl 2006 Jan;12(1):24-30

Australian Safety and Efficacy Register of New Interventional Procedures-Surgical (ASERNIP-S), Royal Australasian College of Surgeons, SA.

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January 2006

Outcomes of split versus reduced-size grafts in pediatric liver transplantation.

J Gastroenterol Hepatol 2005 Dec;20(12):1850-4

Queensland Liver Transplant Service, Royal Children's Hospital, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1111/j.1440-1746.2005.03926.xDOI Listing
December 2005

Synthesis and biological activity of prodrug inhibitors of the thioredoxin-thioredoxin reductase system.

Org Biomol Chem 2005 Nov 28;3(21):3880-2. Epub 2005 Sep 28.

Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260, USA.

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http://dx.doi.org/10.1039/b510718kDOI Listing
November 2005

Evaluation of 3 internal standards for the measurement of cyclosporin by HPLC-mass spectrometry.

Clin Chem 2005 Oct;51(10):1890-3

Department of Clinical Pharmacology, Princess Alexandra Hospital, Brisbane, Australia.

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http://dx.doi.org/10.1373/clinchem.2005.055160DOI Listing
October 2005

Generalized, pruritic, ulcerating maculopapular rash necessitating cessation of sirolimus in a liver transplantation patient.

Liver Transpl 2005 Aug;11(8):987-9

Department of Surgery, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia.

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http://doi.wiley.com/10.1002/lt.20499
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http://dx.doi.org/10.1002/lt.20499DOI Listing
August 2005

A rapid HPLC-mass spectrometry cyclosporin method suitable for current monitoring practices.

Clin Biochem 2005 Jul;38(7):667-73

Australian Bioanalytical Services Pty. Ltd., Princess Alexandra Hospital, QLD, Australia.

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http://dx.doi.org/10.1016/j.clinbiochem.2005.04.009DOI Listing
July 2005

Cycloaddition chemistry of 2-vinyl-substituted indoles and related heteroaromatic systems.

J Org Chem 2005 Mar;70(6):2206-18

Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1021/jo047834aDOI Listing
March 2005

Sampling times for monitoring tacrolimus in stable adult liver transplant recipients.

Ther Drug Monit 2004 Dec;26(6):593-9

School of Pharmacy, University of Queensland, Queensland 4072, Australia.

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http://dx.doi.org/10.1097/00007691-200412000-00003DOI Listing
December 2004

[Liver transplantation for primary biliary cirrhosis: retrospective analysis of 52 patients in QLTS].

Zhonghua Gan Zang Bing Za Zhi 2004 Sep;12(9):543-5

Department of General Surgery, Shandong Provincial Qianfoshan Hospital, Jinan 250014, China.

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September 2004

Natural product based inhibitors of the thioredoxin-thioredoxin reductase system.

Org Biomol Chem 2004 Jun 11;2(11):1651-8. Epub 2004 May 11.

Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260, USA.

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http://dx.doi.org/10.1039/b402431aDOI Listing
June 2004

Solution structure of xDNA: a paired genetic helix with increased diameter.

J Am Chem Soc 2004 Jun;126(22):6900-5

Department of Chemistry, Stanford University, Stanford, California 94305-5080, USA.

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http://dx.doi.org/10.1021/ja0497835DOI Listing
June 2004

A new strategy toward indole alkaloids involving an intramolecular cycloaddition/rearrangement cascade.

J Org Chem 2004 May;69(11):3735-45

Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1021/jo049808iDOI Listing
May 2004

A pharmacodynamic investigation of tacrolimus in pediatric liver transplantation.

Liver Transpl 2004 Apr;10(4):506-12

School of Pharmacy, University of Queensland, Princess Alexandra Hospital, Queensland, Australia.

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http://dx.doi.org/10.1002/lt.20065DOI Listing
April 2004

Effect of atorvastatin on cyclosporine pharmacokinetics in liver transplant recipients.

Ann Pharmacother 2004 Feb 19;38(2):205-8. Epub 2003 Dec 19.

Department of Medicine, University of Queensland, Department of Clinical Pharmacology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1345/aph.1D388DOI Listing
February 2004

Living-donor and split-liver transplantation in adults: right versus left-sided grafts.

J Hepatobiliary Pancreat Surg 2003 ;10(1):5-10

The Hepatobiliary and Liver Transplant Unit, Princess Alexandra Hospital, Brisbane, Australia.

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November 2003

A four-base paired genetic helix with expanded size.

Science 2003 Oct;302(5646):868-71

Department of Chemistry, Stanford University, Stanford, CA 94305-5080, USA.

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http://dx.doi.org/10.1126/science.1088334DOI Listing
October 2003

The influence of viral genotypes and rejection episodes on the recurrence of hepatitis C after liver transplantation.

Surg Today 2003 ;33(6):421-5

The Queensland Liver Transplant Service, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Qld 4102, Australia.

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http://dx.doi.org/10.1007/s10595-002-2537-5DOI Listing
September 2003

Synthesis of highly oxygenated dinaphthyl ethers via SNAr reactions promoted by Barton's base.

Org Lett 2003 Apr;5(7):1155-8

Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.

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http://dx.doi.org/10.1021/ol034286zDOI Listing
April 2003

Toward better outcomes with tacrolimus therapy: population pharmacokinetics and individualized dosage prediction in adult liver transplantation.

Liver Transpl 2003 Feb;9(2):130-7

School of Pharmacy, University of Queensland, Princess Alexandra Hospital, Queensland, Australia.

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http://dx.doi.org/10.1053/jlts.2003.50023DOI Listing
February 2003

Comparison of X-ray crystal structure of the 30S subunit-antibiotic complex with NMR structure of decoding site oligonucleotide-paromomycin complex.

Structure 2003 Jan;11(1):43-53

Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/s0969-2126(02)00934-6DOI Listing
January 2003

Intramolecular amidofuran cycloadditions across an indole pi-bond: an efficient approach to the aspidosperma and strychnos ABCE core.

Org Lett 2002 Dec;4(26):4643-5

Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1021/ol027024qDOI Listing
December 2002

The lytic switch protein of KSHV activates gene expression via functional interaction with RBP-Jkappa (CSL), the target of the Notch signaling pathway.

Genes Dev 2002 Aug;16(15):1977-89

Howard Hughes Medical Institute and Departments of Microbiology and Medicine, University of California, San Francisco, California 94143-0414, USA.

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http://dx.doi.org/10.1101/gad.996502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC186409PMC
August 2002

Quantification and stability of everolimus (SDZ RAD) in human blood by high-performance liquid chromatography-electrospray tandem mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2002 Jun;772(2):283-90

Australian Bioanalytical Services Pty Ltd., First Floor Lions Research Building, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Queensland 4102, Brisbane, Australia.

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http://dx.doi.org/10.1016/s1570-0232(02)00107-1DOI Listing
June 2002

Lymphocyte apoptosis and cell replacement in human liver allografts.

Transplantation 2002 Jun;73(11):1828-34

Department of Pathology, Mayne Medical School, University of Queensland, Herston Road, Herston, Brisbane, Australia 4006.

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http://dx.doi.org/10.1097/00007890-200206150-00022DOI Listing
June 2002

Synthesis of azapolycyclic systems via the intramolecular [4 + 2] cycloaddition chemistry of 2-(alkylthio)-5-amidofurans.

J Org Chem 2002 May;67(10):3412-24

Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1021/jo0111816DOI Listing
May 2002

Cold storage preservation and warm ischaemic injury to isolated arterial segments: endothelial cell injury.

Am J Transplant 2002 May;2(5):400-9

University of Queensland, Department of Surgery, Princess Alexandra Hospital, Brisbane, Queensland, Australia.

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May 2002

Liver transplantation for hepatolithiasis.

Asian J Surg 2002 Apr;25(2):180-3

Hepatobiliary and Liver Transplant Unit, Princess Alexandra Hospital, Brisbane, Australia 4102.

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http://dx.doi.org/10.1016/S1015-9584(09)60170-6DOI Listing
April 2002

Liver transplantation as a therapeutic option for hepatocellular carcinoma.

Oncology 2002 ;62 Suppl 1:82-6

Department of Surgery, Matsunami General Hospital, Gifu, Japan.

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http://dx.doi.org/10.1159/000048281DOI Listing
March 2002

Influence of ground-state conformations on the intramolecular amidofuran Diels-Alder reaction.

Org Lett 2002 Feb;4(4):473-6

Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1021/ol016804gDOI Listing
February 2002