Stephen J Wort

Stephen J Wort

UNVERIFIED PROFILE

Are you Stephen J Wort?   Register this Author

Register author
Stephen J Wort

Stephen J Wort

Publications by authors named "Stephen J Wort"

Are you Stephen J Wort?   Register this Author

68Publications

1937Reads

50Profile Views

EmPHasis-10 score for the assessment of quality of life in various types of pulmonary hypertension and its relation to outcome.

Eur J Prev Cardiol 2019 Aug 19;26(12):1338-1340. Epub 2018 Dec 19.

1 Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2047487318819161DOI Listing
August 2019

A single-centre, placebo-controlled, double-blind randomised cross-over study of nebulised iloprost in patients with Eisenmenger syndrome: A pilot study.

Int J Cardiol 2019 Jul 4. Epub 2019 Jul 4.

Adult Congenital Heart Disease Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital London, United Kingdom; National Heart and Lung Institute, Imperial College, London, United Kingdom. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2019.07.004DOI Listing
July 2019

Eisenmenger syndrome and other types of pulmonary arterial hypertension related to adult congenital heart disease.

Expert Rev Cardiovasc Ther 2019 Jun 6;17(6):449-459. Epub 2019 Jun 6.

a Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension , National Heart and Lung Institute, Biomedical Research Unit, Royal Brompton Hospital, Imperial College , London , UK.

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/14779072.2019.1
Publisher Site
http://dx.doi.org/10.1080/14779072.2019.1623024DOI Listing
June 2019

Heart or heart-lung transplantation for patients with congenital heart disease in England.

Heart 2019 04 12;105(8):596-602. Epub 2019 Jan 12.

Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/heartjnl-2018-313984DOI Listing
April 2019

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.

Authors:
Christopher J Rhodes Ken Batai Marta Bleda Matthias Haimel Laura Southgate Marine Germain Michael W Pauciulo Charaka Hadinnapola Jurjan Aman Barbara Girerd Amit Arora Jo Knight Ken B Hanscombe Jason H Karnes Marika Kaakinen Henning Gall Anna Ulrich Lars Harbaum Inês Cebola Jorge Ferrer Katie Lutz Emilia M Swietlik Ferhaan Ahmad Philippe Amouyel Stephen L Archer Rahul Argula Eric D Austin David Badesch Sahil Bakshi Christopher Barnett Raymond Benza Nitin Bhatt Harm J Bogaard Charles D Burger Murali Chakinala Colin Church John G Coghlan Robin Condliffe Paul A Corris Cesare Danesino Stéphanie Debette C Gregory Elliott Jean Elwing Melanie Eyries Terry Fortin Andre Franke Robert P Frantz Adaani Frost Joe G N Garcia Stefano Ghio Hossein-Ardeschir Ghofrani J Simon R Gibbs John Harley Hua He Nicholas S Hill Russel Hirsch Arjan C Houweling Luke S Howard Dunbar Ivy David G Kiely James Klinger Gabor Kovacs Tim Lahm Matthias Laudes Rajiv D Machado Robert V MacKenzie Ross Keith Marsolo Lisa J Martin Shahin Moledina David Montani Steven D Nathan Michael Newnham Andrea Olschewski Horst Olschewski Ronald J Oudiz Willem H Ouwehand Andrew J Peacock Joanna Pepke-Zaba Zia Rehman Ivan Robbins Dan M Roden Erika B Rosenzweig Ghulam Saydain Laura Scelsi Robert Schilz Werner Seeger Christian M Shaffer Robert W Simms Marc Simon Olivier Sitbon Jay Suntharalingam Haiyang Tang Alexander Y Tchourbanov Thenappan Thenappan Fernando Torres Mark R Toshner Carmen M Treacy Anton Vonk Noordegraaf Quinten Waisfisz Anna K Walsworth Robert E Walter John Wharton R James White Jeffrey Wilt Stephen J Wort Delphine Yung Allan Lawrie Marc Humbert Florent Soubrier David-Alexandre Trégouët Inga Prokopenko Richard Kittles Stefan Gräf William C Nichols Richard C Trembath Ankit A Desai Nicholas W Morrell Martin R Wilkins

Lancet Respir Med 2019 Mar 5;7(3):227-238. Epub 2018 Dec 5.

Department of Medicine, Imperial College London, London, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2213-2600(18)30409-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391516PMC
March 2019

Incidence, mortality and bleeding rates associated with pulmonary embolism in England between 1997 and 2015.

Int J Cardiol 2019 Feb 2;277:229-234. Epub 2018 Oct 2.

Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital, Imperial College, London, UK.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01675273183265
Publisher Site
http://dx.doi.org/10.1016/j.ijcard.2018.10.001DOI Listing
February 2019

Arrhythmias in adult patients with congenital heart disease and pulmonary arterial hypertension.

Heart 2018 12 18;104(23):1963-1969. Epub 2018 May 18.

Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital, National Heart and Lung Institute, Imperial College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/heartjnl-2017-312881DOI Listing
December 2018

Use of intravenous iron in cyanotic patients with congenital heart disease and/or pulmonary hypertension.

Int J Cardiol 2018 Sep 19;267:79-83. Epub 2018 May 19.

Adult Congenital Heart Centre and Centre for Pulmonary Hypertension, Royal Brompton Hospital, London, UK; National Heart and Lung Institute, Imperial College School of Medicine, London, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2018.05.062DOI Listing
September 2018

Atrial septal defects and pulmonary arterial hypertension.

J Thorac Dis 2018 Sep;10(Suppl 24):S2953-S2965

Department of Adult Congenital Heart Disease, Royal Brompton and Harefield NHS Foundation Trust, National Heart and Lung Institute, Imperial College London, London, UK.

View Article

Download full-text PDF

Source
http://jtd.amegroups.com/article/view/23699/18018
Publisher Site
http://dx.doi.org/10.21037/jtd.2018.08.92DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174141PMC
September 2018

Pulmonary Arterial Hypertension: Iron Matters.

Front Physiol 2018 31;9:641. Epub 2018 May 31.

Cardiorespiratory Interface - Vascular Biology, The National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fphys.2018.00641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990599PMC
May 2018

miR-424-5p reduces ribosomal RNA and protein synthesis in muscle wasting.

J Cachexia Sarcopenia Muscle 2018 04 7;9(2):400-416. Epub 2017 Dec 7.

Molecular Medicine Section, National Heart and Lung Institute, Imperial College London, South Kensington Campus, London, SW7 2AZ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcsm.12266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879973PMC
April 2018

Year in review 2017: Interstitial lung disease, pulmonary vascular disease and sleep.

Respirology 2018 04 22;23(4):421-433. Epub 2018 Feb 22.

Interstitial Lung Disease Unit, Royal Brompton Hospital, Imperial College, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/resp.13273DOI Listing
April 2018

Balloon pulmonary angioplasty for chronic thromboembolic disease: aiming for perfection.

EuroIntervention 2018 04;13(17):1983-1986

Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4244/EIJV13I17A323DOI Listing
April 2018

miR-322-5p targets IGF-1 and is suppressed in the heart of rats with pulmonary hypertension.

FEBS Open Bio 2018 03 24;8(3):339-348. Epub 2018 Jan 24.

Molecular Medicine National Heart & Lung Institute Imperial College London UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/2211-5463.12369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832985PMC
March 2018

Pulmonary arteriovenous malformations emerge from the shadows.

Thorax 2017 12;72(12):1071-1073

NHLI Vascular Science, Imperial College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/thoraxjnl-2017-211072DOI Listing
December 2017

British Thoracic Society Clinical Statement on Pulmonary Arteriovenous Malformations.

Thorax 2017 12;72(12):1154-1163

Pulmonary Hypertension Department, Royal Brompton Hospital, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/thoraxjnl-2017-210764DOI Listing
December 2017

Pulmonary Arterial Hypertension Complicating Congenital Heart Disease: Advances in Therapy.

Semin Respir Crit Care Med 2017 10 15;38(5):636-650. Epub 2017 Oct 15.

Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0037-1606222DOI Listing
October 2017

Outcome of cardiac surgery in patients with congenital heart disease in England between 1997 and 2015.

PLoS One 2017 19;12(6):e0178963. Epub 2017 Jun 19.

Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital, Imperial College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0178963PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476245PMC
September 2017

Response by Kempny et al to Letter Regarding Article, "Predictors of Death in Contemporary Adult Patients With Eisenmenger Syndrome: A Multicenter Study".

Circulation 2017 09;136(11):1078-1079

From Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, National Heart and Lung Institute, Biomedical Research Unit, Royal Brompton Hospital, Imperial College, London, United Kingdom (A.K., W.L., G.-P.D., K.D., S.J.W., M.A.G.); and Department of Cardiology, Rigshospitalet, Copenhagen, Denmark (C.S.H., A.S.J., L.S.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.117.029768DOI Listing
September 2017

Survival in portopulmonary hypertension: Outcomes of the United Kingdom National Pulmonary Arterial Hypertension Registry.

J Heart Lung Transplant 2017 Jul 31;36(7):770-779. Epub 2016 Dec 31.

National Pulmonary Hypertension Service (Newcastle), The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.healun.2016.12.014DOI Listing
July 2017

Year in review 2016: Interstitial lung disease, pulmonary vascular disease, pulmonary function, paediatric lung disease, cystic fibrosis and sleep.

Respirology 2017 07 25;22(5):1022-1034. Epub 2017 May 25.

Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/resp.13080DOI Listing
July 2017

Predictors of Death in Contemporary Adult Patients With Eisenmenger Syndrome: A Multicenter Study.

Circulation 2017 Apr 15;135(15):1432-1440. Epub 2016 Dec 15.

From Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, National Heart and Lung Institute, Biomedical Research Unit, Royal Brompton Hospital, Imperial College, London, UK (A.K., W.L., G.-P.D., K.D., S.T.W., M.A.G.); Department of Cardiology, Rigshospitalet, Copenhagen, Denmark (C.S.H., A.S.J., L.S.); Beijing Anzhen Hospital, Capital Medical University, China (G.H.); Boston Adult Congenital Heart and Pulmonary Hypertension Service, Boston Children's Hospital and Brigham and Women's Hospital, Harvard Medical School, MA (A.R.O., M.J.L.); Department of Cardiology, University Hospitals Leuven, Belgium (W.B.); Department of Cardiology, Academic Medical Center, Amsterdam, Netherlands (B.J.M., I.B.); Institute of Cardiology, Jagiellonian University Medical College, Cracow, Poland (L.T.-P.); AGH University of Science and Technology, Cracow, Poland (K.S.); Department of Cardiology, Second University of Naples, Italy (M.D'A., G.S.); Adult Congenital Heart Centre, University Medical Center, Ljubljana, Slovenia (K.P.); Department of Cardiology, Rikshospitalet Oslo University Hospital, Norway (M.-E.E.); and Department of Cardiology, Lund University Hospital, Sweden (U.T.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.116.023033DOI Listing
April 2017

Pulmonary tumour thrombotic microangiopathy.

Curr Opin Pulm Med 2016 09;22(5):421-8

aNational Pulmonary Hypertension Service bInterstitial Lung Disease Unit, Royal Brompton Hospital, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MCP.0000000000000297DOI Listing
September 2016

Dynamic Risk Stratification of Patient Long-Term Outcome After Pulmonary Endarterectomy: Results From the United Kingdom National Cohort.

Circulation 2016 May 6;133(18):1761-71. Epub 2016 Apr 6.

From Papworth Hospital, Cambridge, United Kingdom (J.E.C., K.P., M.T., E.S., C.T., A. Ponnaberanam, K.S., D.T., J.D., S.T., C.N., N.S., D.P.T., J.P.-Z.); MRC Biostatistics Unit, Cambridge, United Kingdom (L.S.); Royal Hallamshire Hospital, Sheffield, United Kingdom (D.G.K., R.C., C.E.); Respiratory Medicine Department, University of Warmia and Mazury, Poland (E.S.); Hammersmith Hospital, London, United Kingdom (D.G., S. Gibbs, L.H.); Freeman Hospital, Newcastle, United Kingdom (P.C., J.L.); Golden Jubilee Hospital, Glasgow, United Kingdom (M.J., A. Peacock); Royal United Hospital, Bath, United Kingdom (R.M.-R.); Royal Free Hospital, London, United Kingdom (B.S., G.C.); Royal Brompton Hospital, London, United Kingdom (K.D., J.W.); Mater Misericordiae University Hospital, Dublin, Ireland (S. Gaine); and Great Ormond Street Hospital, London, United Kingdom (S.M.).

View Article

Download full-text PDF

Source
http://circ.ahajournals.org/content/early/2016/04/06/CIRCULA
Web Search
http://circ.ahajournals.org/content/early/2016/04/06/CIRCULA
Web Search
http://circ.ahajournals.org/lookup/doi/10.1161/CIRCULATIONAH
Publisher Site
http://dx.doi.org/10.1161/CIRCULATIONAHA.115.019470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860739PMC
May 2016

Year in review 2015: Interstitial lung disease, pulmonary vascular disease, pulmonary function, sleep and ventilation, cystic fibrosis and paediatric lung disease.

Respirology 2016 Apr 24;21(3):556-66. Epub 2016 Feb 24.

Lady Cilento Children's Hospital, School of Medicine, University of Queensland, Brisbane, Queensland, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/resp.12749DOI Listing
April 2016

Percutaneous transluminal pulmonary angioplasty for the treatment of chronic thromboembolic pulmonary hypertension: Challenges and future directions.

Int J Cardiol 2015 27;187:401-3. Epub 2015 Mar 27.

Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital, London, UK; NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, UK; National Heart and Lung Institute, Imperial College School of Medicine, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2015.03.361DOI Listing
February 2016

Determinants of outpatient clinic attendance amongst adults with congenital heart disease and outcome.

Int J Cardiol 2016 Jan 22;203:245-50. Epub 2015 Oct 22.

Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, UK; National Heart and Lung Institute, Imperial College School of Medicine, London, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2015.10.081DOI Listing
January 2016

Survival Prospects and Circumstances of Death in Contemporary Adult Congenital Heart Disease Patients Under Follow-Up at a Large Tertiary Centre.

Circulation 2015 Dec 14;132(22):2118-25. Epub 2015 Sep 14.

From Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital, London, United Kingdom (G.-P.D., A.K., R.A.-G., L.S., A.U., W.L., S.B.-N., S.J.W., K.D., M.A.G.); NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, United Kingdom (G.-P.D., A.K., R.A.-G., L.S., A.U., W.L., S.B.-N., S.J.W., K.D., M.A.G.); National Heart and Lung Institute, Imperial College School of Medicine, London, United Kingdom (G.-P.D., A.K., R.A.-G., L.S., A.U., W.L., S.B.-N., S.J.W., K.D., M.A.G.); and Division of Adult Congenital and Valvular Heart Disease, Department of Cardiology and Angiology, University Hospital Muenster, Germany (G.-P.D.).

View Article

Download full-text PDF

Source
http://circ.ahajournals.org/content/early/2015/09/14/CIRCULA
Web Search
http://circ.ahajournals.org/lookup/doi/10.1161/CIRCULATIONAH
Publisher Site
http://dx.doi.org/10.1161/CIRCULATIONAHA.115.017202DOI Listing
December 2015

Impaired Right, Left, or Biventricular Function and Resting Oxygen Saturation Are Associated With Mortality in Eisenmenger Syndrome: A Clinical and Cardiovascular Magnetic Resonance Study.

Circ Cardiovasc Imaging 2015 Dec;8(12)

From the National Institute for Health Research Cardiovascular Biomedical Research Unit, Royal Brompton and Harefield NHS Foundation Trust, National Heart and Lung Institute, Imperial College London, London, United Kingdom (A.S.J., C.S.B., R.R., G.-P.D., W.L., K.D., J.S.W., D.J.P., M.A.G., S.V.B.-N.); Department of Cardiology, Rigshospitalet, Copenhagen, Denmark (A.S.J.); Adult Congenital Heart Program, Knight Cardiovascular Institute, Oregon Health and Science University Portland (C.S.B.); Section of Clinical Physiology, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden (R.R.); and Division of Adult Congenital and Valvular Heart Disease, Department of Cardiovascular Medicine, University Hospital Muenster, Muenster, Germany (G.-P.D.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCIMAGING.115.003596DOI Listing
December 2015

Hypoalbuminaemia predicts outcome in adult patients with congenital heart disease.

Heart 2015 May 3;101(9):699-705. Epub 2015 Mar 3.

Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital, London, UK NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, UK National Heart and Lung Institute, Imperial College School of Medicine, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/heartjnl-2014-306970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413739PMC
May 2015

Physiological differences between various types of Eisenmenger syndrome and relation to outcome.

Int J Cardiol 2015 Jan 13;179:455-60. Epub 2014 Nov 13.

Adult Congenital Heart Centre and Centre for Pulmonary Hypertension, Royal Brompton Hospital, London, UK; NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital and National Heart and Lung Institute, Imperial College School of Medicine, London, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2014.11.100DOI Listing
January 2015

C-reactive protein in adults with pulmonary arterial hypertension associated with congenital heart disease and its prognostic value.

Heart 2014 Sep 1;100(17):1335-41. Epub 2014 May 1.

Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital, London, UK NIHR Cardiovascular Biomedical Research Unit, Royal Brompton Hospital and National Heart and Lung Institute, Imperial College London, London, UK National Heart and Lung Institute, Imperial College School of Medicine, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/heartjnl-2014-305494DOI Listing
September 2014

Evidence for the involvement of type I interferon in pulmonary arterial hypertension.

Circ Res 2014 Feb 13;114(4):677-88. Epub 2013 Dec 13.

From the Department of Cardiothoracic Pharmacology, National Heart and Lung Institute, Imperial College London, United Kingdom (P.M.G., D.M.R., N.S.K., N.A.M., S.J.W., J.A.M.); Centre for Pharmacology and Therapeutics, Experimental Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom (E.O., O.D.D., L.Z.); Service d'Anatomie Pathologique, Centre Chirurgical Marie Lannelongue, Le Plessis-Robinson, France (P.D.); Univ. Paris-Sud, Faculté de médecine, Kremlin-Bicêtre, France (P.D., F.P., F.A., M.H.); INSERM UMR-S 999, Labex LERMIT, Hypertension Artérielle Pulmonaire: Physiopathologie et Innovation Thérapeutique, Centre Chirurgical Marie Lannelongue, Le Plessis-Robinson, France (P.D., F.P., F.A., E.F., M.H.); AP-HP, DHU TORINO, Centre de Référence de l'Hypertension Pulmonaire Sévère, Service de Pneumologie et Réanimation Respiratoire, Hôpital Bicêtre, Le Kremlin-Bicêtre, France (F.P., F.A., M.H.); Pulmonary Hypertension service, Royal Free Hospital, London, United Kingdom (B.E.S., J.G.C.); Centre for Rheumatology and Connective Tissue Diseases, Department of Inflammation, University College London, Royal Free Campus, London, United Kingdom (A.M.H.); Pulmonary Vascular Diseases Unit, Papworth Hospital NHS Trust, Papworth Everard, Cambridge (M.S., G.H., N.W.M.); and National Heart & Lung Institute, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, Centre for Respiratory Infection, Imperial College London, United Kingdom (N.B.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCRESAHA.114.302221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006084PMC
February 2014

Six-minute walk test distance and resting oxygen saturations but not functional class predict outcome in adult patients with Eisenmenger syndrome.

Int J Cardiol 2013 Oct 2;168(5):4784-9. Epub 2013 Aug 2.

Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital, London, UK; National Heart and Lung Institute, Imperial College School of Medicine, London, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2013.07.227DOI Listing
October 2013

Viral Toll Like Receptor activation of pulmonary vascular smooth muscle cells results in endothelin-1 generation; relevance to pathogenesis of pulmonary arterial hypertension.

Biochem Biophys Res Commun 2012 Oct 28;426(4):486-91. Epub 2012 Aug 28.

Cardiothoracic Pharmacology, National Heart and Lung Institute, Imperial College London, Dovehouse Street, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2012.08.106DOI Listing
October 2012

Echocardiographic predictors of outcome in eisenmenger syndrome.

Circulation 2012 Sep 16;126(12):1461-8. Epub 2012 Aug 16.

Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.112.091421DOI Listing
September 2012

BMP-9 induced endothelial cell tubule formation and inhibition of migration involves Smad1 driven endothelin-1 production.

PLoS One 2012 27;7(1):e30075. Epub 2012 Jan 27.

Unit of Critical Care, Royal Brompton Hospital, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0030075PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267722PMC
July 2012

Pulmonary hypertension in left heart disease: a review.

Int J Cardiol 2012 May 23;156(3):253-8. Epub 2011 Jun 23.

Department of Pulmonary Hypertension, Royal Brompton Hospital, National Heart and Lung Institute, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2011.06.013DOI Listing
May 2012

Pulmonary vascular and right ventricular dysfunction in adult critical care: current and emerging options for management: a systematic literature review.

Crit Care 2010 21;14(5):R169. Epub 2010 Sep 21.

Department of Critical Care, National Heart and Lung Institute, Imperial College London, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/cc9264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219266PMC
September 2011

The role of endothelin-1 in the pathogenesis of pulmonary arterial hypertension.

Pharmacol Res 2011 Jun 16;63(6):504-11. Epub 2011 Mar 16.

Department of Adult Intensive Care Unit, Royal Brompton Hospital, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London SW36LY, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phrs.2011.03.003DOI Listing
June 2011

Pulmonary hypertension in sarcoidosis: a review.

Respirology 2011 Jan;16(1):69-77

Royal Brompton Hospital and National Heart and Lung Institute Imperial College, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1440-1843.2010.01872.xDOI Listing
January 2011

Detection of pulmonary hypertension with multidetector CT and echocardiography alone and in combination.

Radiology 2010 Feb;254(2):609-16

Department of Radiology, Royal Brompton Hospital, Sydney Street, London, SW3 6NP, England.

View Article

Download full-text PDF

Source
http://pubs.rsna.org/doi/10.1148/radiol.09090548
Publisher Site
http://dx.doi.org/10.1148/radiol.09090548DOI Listing
February 2010

Improved survival among patients with Eisenmenger syndrome receiving advanced therapy for pulmonary arterial hypertension.

Circulation 2010 Jan 21;121(1):20-5. Epub 2009 Dec 21.

Adult Congenital Heart Centre and Centre for Pulmonary Hypertension, Royal Brompton Hospital, London, UK.

View Article

Download full-text PDF

Source
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.109.8
Publisher Site
http://dx.doi.org/10.1161/CIRCULATIONAHA.109.883876DOI Listing
January 2010

Role of pravastatin in pulmonary hypertension in chronic obstructive pulmonary disease.

Clin Sci (Lond) 2009 Mar;116(6):493-5

Department of Pulmonary Hypertension, Royal Brompton Hospital. Sydney St, London SW3 6NP, UK.

View Article

Download full-text PDF

Source
http://www.clinsci.org/cgi/doi/10.1042/CS20080590
Publisher Site
http://dx.doi.org/10.1042/CS20080590DOI Listing
March 2009

Role for nuclear factor-kappaB and signal transducer and activator of transcription 1/interferon regulatory factor-1 in cytokine-induced endothelin-1 release in human vascular smooth muscle cells.

Mol Pharmacol 2003 Oct;64(4):923-31

Department of Cardiac, Vascular and Inflammation Research, The William Harvey Research Institute, St. Bartholomew's and the Royal London School of Medicine and Dentistry, Charterhouse Square, London, EC1M 6BQ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/mol.64.4.923DOI Listing
October 2003

Cyclooxygenase-2 acts as an endogenous brake on endothelin-1 release by human pulmonary artery smooth muscle cells: implications for pulmonary hypertension.

Mol Pharmacol 2002 Nov;62(5):1147-53

Unit of Critical Care Medicine, Imperial College School of Medicine, Royal Brompton Hospital, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/mol.62.5.1147DOI Listing
November 2002