Stephen J Meltzer

Stephen J Meltzer

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Stephen J Meltzer

Publications by authors named "Stephen J Meltzer"

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Krüppel-like Factor 5 Promotes Sonic Hedgehog Signaling and Neoplasia in Barrett's Esophagus and Esophageal Adenocarcinoma.

Transl Oncol 2019 Nov 8;12(11):1432-1441. Epub 2019 Aug 8.

Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tranon.2019.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700477PMC
November 2019

Synthetic circular multi-miR sponge simultaneously inhibits miR-21 and miR-93 in esophageal carcinoma.

Lab Invest 2019 Oct 19;99(10):1442-1453. Epub 2019 Jun 19.

Division of Gastroenterology, Department of Medicine, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.

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http://dx.doi.org/10.1038/s41374-019-0273-2DOI Listing
October 2019

Epigenetic alterations of a novel antioxidant gene predispose susceptible individuals to increased risk of esophageal cancer.

Int J Biol Sci 2018 7;14(12):1658-1668. Epub 2018 Sep 7.

Guangdong Key Laboratory for Genome Stability & Disease Prevention, Department of Pharmacology and Carson International Cancer Center, Shenzhen University School of Medicine, Shenzhen 518039, China.

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http://dx.doi.org/10.7150/ijbs.28482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216027PMC
September 2019

Evaluation of Salivary Exosomal Chimeric RNA as a Potential Biomarker in Esophageal Carcinoma.

Clin Cancer Res 2019 05 11;25(10):3035-3045. Epub 2019 Feb 11.

Institute of Precision Cancer Medicine and Pathology, Jinan University Medical College, Guangzhou, Guangdong, China.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-3169DOI Listing
May 2019

Synthetic Circular RNA Functions as a miR-21 Sponge to Suppress Gastric Carcinoma Cell Proliferation.

Mol Ther Nucleic Acids 2018 Dec 22;13:312-321. Epub 2018 Sep 22.

Division of Gastroenterology, Department of Medicine, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, MD 21205, USA; Division of Gastroenterology, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, MD 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2018.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197335PMC
December 2018

Inhibition of miR‑194 suppresses the Wnt/β‑catenin signalling pathway in gastric cancer.

Oncol Rep 2018 Dec 8;40(6):3323-3334. Epub 2018 Oct 8.

Guangdong Key Laboratory for Genome Stability & Disease Prevention, Department of Pathology, The Shenzhen University School of Medicine, Shenzhen, Guangdong 518060, P.R. China.

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http://dx.doi.org/10.3892/or.2018.6773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196585PMC
December 2018

Novel circular RNA NF1 acts as a molecular sponge, promoting gastric cancer by absorbing miR-16.

Endocr Relat Cancer 2018 12 1. Epub 2018 Dec 1.

S Meltzer, Division of Gastroenterology, Department of Medicine, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, United States.

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https://erc.bioscientifica.com/view/journals/erc/26/3/ERC-18
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http://dx.doi.org/10.1530/ERC-18-0478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545167PMC
December 2018

Modeling Wnt signaling by CRISPR-Cas9 genome editing recapitulates neoplasia in human Barrett epithelial organoids.

Cancer Lett 2018 11 23;436:109-118. Epub 2018 Aug 23.

Division of Gastroenterology, Department of Medicine, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA; Division of Gastroenterology, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2018.08.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152930PMC
November 2018

Inhibition of the miR-192/215-Rab11-FIP2 axis suppresses human gastric cancer progression.

Cell Death Dis 2018 07 13;9(7):778. Epub 2018 Jul 13.

Department of Pathology, School of Basic Medical Sciences, Guangdong Key Laboratory for Genome Stability & Disease Prevention, Shenzhen Key Laboratory of Micromolecule Innovatal Drugs, Shenzhen University Health Sciences Center, Shenzhen, Guangdong, People's Republic of China.

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http://dx.doi.org/10.1038/s41419-018-0785-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045576PMC
July 2018

Super-Enhancer-Driven Long Non-Coding RNA LINC01503, Regulated by TP63, Is Over-Expressed and Oncogenic in Squamous Cell Carcinoma.

Gastroenterology 2018 06 15;154(8):2137-2151.e1. Epub 2018 Feb 15.

Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California; Cancer Science Institute of Singapore, National University of Singapore, Singapore; National University Cancer Institute, National University Hospital Singapore, Singapore.

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http://dx.doi.org/10.1053/j.gastro.2018.02.018DOI Listing
June 2018

Nearly a Third of High-Grade Dysplasia and Colorectal Cancer Is Undetected in Patients with Inflammatory Bowel Disease.

Dig Dis Sci 2017 12 19;62(12):3586-3593. Epub 2017 Jun 19.

Division of Gastroenterology and Hepatology, School of Medicine, University of North Carolina at Chapel Hill, 4119B Bioinformatics Building, 130 Mason Farm Road, Chapel Hill, NC, 27599-7080, USA.

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http://dx.doi.org/10.1007/s10620-017-4652-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435268PMC
December 2017

Esophageal Adenocarcinoma-Derived Extracellular Vesicle MicroRNAs Induce a Neoplastic Phenotype in Gastric Organoids.

Neoplasia 2017 Nov 29;19(11):941-949. Epub 2017 Sep 29.

Department of Medicine (GI Division), the Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA; Department of Oncology, the Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2017.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633352PMC
November 2017

Proton Pump Inhibitors Do Not Reduce the Risk of Esophageal Adenocarcinoma in Patients with Barrett's Esophagus: A Systematic Review and Meta-Analysis.

PLoS One 2017 10;12(1):e0169691. Epub 2017 Jan 10.

Division of Gastroenterology, Department of Medicine and Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0169691PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224998PMC
August 2017

Long Noncoding RNAs in the Pathogenesis of Barrett's Esophagus and Esophageal Carcinoma.

Gastroenterology 2017 07 18;153(1):27-34. Epub 2017 May 18.

Department of Medicine/Gastroenterology Division and Sidney Kimmel Comprehensive Cancer Center, the Johns Hopkins University School of Medicine, Baltimore, Maryland 21287. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.04.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515484PMC
July 2017

Gastric Cancer in the Era of Precision Medicine.

Cell Mol Gastroenterol Hepatol 2017 May 20;3(3):348-358. Epub 2017 Feb 20.

Division of Gastroenterology, Department of Medicine, and Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1016/j.jcmgh.2017.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404028PMC
May 2017

MiRNA-194 activates the Wnt/β-catenin signaling pathway in gastric cancer by targeting the negative Wnt regulator, SUFU.

Cancer Lett 2017 01 31;385:117-127. Epub 2016 Oct 31.

Department of Medicine/GI Division and Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.canlet.2016.10.035DOI Listing
January 2017

Leaky transporters and sphincters in Barrett's oesophagus?

Lancet Oncol 2016 10 12;17(10):1336-1337. Epub 2016 Aug 12.

The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(16)30365-5DOI Listing
October 2016

TNFAIP8 overexpression: a potential predictor of lymphatic metastatic recurrence in pN0 esophageal squamous cell carcinoma after Ivor Lewis esophagectomy.

Tumour Biol 2016 Aug 17;37(8):10923-34. Epub 2016 Feb 17.

Department of Thoracic Surgery, Provincial Hospital Affiliated to Shandong University, 324 Jingwu Road, Jinan, 250021, Shandong, China.

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http://dx.doi.org/10.1007/s13277-016-4978-1DOI Listing
August 2016

Paf15 expression correlates with rectal cancer prognosis, cell proliferation and radiation response.

Oncotarget 2016 Jun;7(25):38750-38761

Department of Surgical Oncology, The First Affiliated Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi, China.

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http://dx.doi.org/10.18632/oncotarget.9606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122426PMC
June 2016

Phosphorus-32, a clinically available drug, inhibits cancer growth by inducing DNA double-strand breakage.

PLoS One 2015 1;10(6):e0128152. Epub 2015 Jun 1.

Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0128152PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450878PMC
April 2016

Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers.

Gastroenterology 2016 Apr 5;150(4):931-43. Epub 2016 Jan 5.

Ludwig Center at Johns Hopkins, Baltimore, Maryland; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2015.12.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270616PMC
April 2016

Klotho: a tumor suppressor and modulator of the Wnt/β-catenin pathway in human hepatocellular carcinoma.

Lab Invest 2016 Feb 3;96(2):197-205. Epub 2015 Aug 3.

Departments of Medicine (Gastroenterology Division) and Oncology, Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA.

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http://dx.doi.org/10.1038/labinvest.2015.86DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731258PMC
February 2016

Differential methylation of the promoter and first exon of the RASSF1A gene in hepatocarcinogenesis.

Hepatol Res 2015 Nov 9;45(11):1110-23. Epub 2014 Dec 9.

Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1111/hepr.12449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426255PMC
November 2015

TQ inhibits hepatocellular carcinoma growth in vitro and in vivo via repression of Notch signaling.

Oncotarget 2015 Oct;6(32):32610-21

Department of Gastroenterology, the First Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China.

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http://dx.doi.org/10.18632/oncotarget.5362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741716PMC
October 2015

LINE-1 expression and retrotransposition in Barrett's esophagus and esophageal carcinoma.

Proc Natl Acad Sci U S A 2015 Sep 17;112(35):E4894-900. Epub 2015 Aug 17.

McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205;

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http://dx.doi.org/10.1073/pnas.1502474112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568228PMC
September 2015

Effects of vitamin D3 stimulation of thioredoxin-interacting protein in hepatocellular carcinoma.

Hepatol Res 2014 Dec 25;44(13):1357-66. Epub 2014 Mar 25.

Division of Gastroenterology and Hepatology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1111/hepr.12302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107198PMC
December 2014

Tumor suppression by miR-31 in esophageal carcinoma is p21-dependent.

Genes Cancer 2014 Nov;5(11-12):436-44

Department of Biotherapy and Gastrointestinal Medical Oncology, Affiliated Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China ; Tumor Tissue Bank, Affiliated Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China ; Cancer Research Center, Shantou University Medical College, Shantou, Guangdong, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279440PMC
http://dx.doi.org/10.18632/genesandcancer.38DOI Listing
November 2014

Evidence for enhanced telomerase activity in Barrett's esophagus with dysplasia and adenocarcinoma.

Asian Pac J Cancer Prev 2013 ;14(2):679-83

Surgery and Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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http://dx.doi.org/10.7314/apjcp.2013.14.2.679DOI Listing
July 2014

Genome-wide and gene-specific epigenomic platforms for hepatocellular carcinoma biomarker development trials.

Gastroenterol Res Pract 2014 17;2014:597164. Epub 2014 Apr 17.

Department of Otolaryngology, Division of Head and Neck Cancer Research, School of Medicine, The Johns Hopkins University, Baltimore, MD 21231, USA ; Department of Obstetrics and Gynecology, University of Puerto Rico School of Medicine, San Juan, PR 00927, USA.

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http://dx.doi.org/10.1155/2014/597164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009191PMC
May 2014

Temporal evolution in caveolin 1 methylation levels during human esophageal carcinogenesis.

BMC Cancer 2014 May 20;14:345. Epub 2014 May 20.

Department of Pathology, The Shenzhen University School of Medicine, 3688 Nanhai Ave, Rm 703, Nanshan, Shenzhen 518060, Guangdong, People's Republic of China.

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http://dx.doi.org/10.1186/1471-2407-14-345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035847PMC
May 2014

A sequence variant in the phospholipase C epsilon C2 domain is associated with esophageal carcinoma and esophagitis.

Mol Carcinog 2013 Nov 6;52 Suppl 1:E80-6. Epub 2013 Feb 6.

Department of Pathology, Xinxiang Medical University, Xinxiang, China; Henan Key Laboratory for Esophageal Cancer Research, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

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http://dx.doi.org/10.1002/mc.22016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931523PMC
November 2013

Aberrant methylation of the Ras-related associated with diabetes gene in human primary esophageal cancer.

Anticancer Res 2013 Nov;33(11):5199-203

The Shenzhen University School of Medicine. 3688 Nanhai Ave, Rm 703, Nanshan, Shenzhen, Guangdong, People's Republic of China 518060. Tel: +86 075586671904,

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http://ar.iiarjournals.org/content/33/11/5199.full.pdf
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November 2013

Endoglin promoter hypermethylation identifies a field defect in human primary esophageal cancer.

Cancer 2013 Oct 24;119(20):3604-9. Epub 2013 Jul 24.

Department of Pathology, The Shenzhen University School of Medicine, Shenzhen, Guangdong, People's Republic of China; Shenzhen Key Laboratory of Micromolecule Innovative Drugs, Shenzhen, Guangdong, People's Republic of China; Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, Guangdong, People's Republic of China.

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http://dx.doi.org/10.1002/cncr.28276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796027PMC
October 2013

MAL hypermethylation is a tissue-specific event that correlates with MAL mRNA expression in esophageal carcinoma.

Sci Rep 2013 Oct 3;3:2838. Epub 2013 Oct 3.

1] Department of Pathology, The Shenzhen University School of Medicine, Shenzhen, Guangdong, People's Republic of China [2] Shenzhen Key Laboratory of Micromolecule Innovatal Drugs, Shenzhen, Guangdong, People's Republic of China [3] Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, Guangdong, People's Republic of China [4].

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http://dx.doi.org/10.1038/srep02838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789153PMC
October 2013

Prohibitin attenuates colitis-associated tumorigenesis in mice by modulating p53 and STAT3 apoptotic responses.

Cancer Res 2012 Nov 6;72(22):5778-89. Epub 2012 Aug 6.

Department of Internal Medicine, Division of Gastroenterology, Baylor Research Institute, Baylor University Medical Center, Dallas, Texas 75246, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-0603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500430PMC
November 2012

Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma.

Cancer Discov 2012 Oct 9;2(10):899-905. Epub 2012 Aug 9.

Ludwig Center for Cancer Genetics and Therapeutics and Howard Hughes Medical Institutions, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-12-0189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473124PMC
October 2012

Consensus statements for management of Barrett's dysplasia and early-stage esophageal adenocarcinoma, based on a Delphi process.

Gastroenterology 2012 Aug 24;143(2):336-46. Epub 2012 Apr 24.

Queens University, Belfast, UK.

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http://dx.doi.org/10.1053/j.gastro.2012.04.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538857PMC
August 2012

Stomach - Genetic and epigenetic alterations of preneoplastic and neoplastic lesions.

Cancer Biomark 2010 ;9(1-6):493-507

Department of Medicine, Division of Gastroenterology, Johns Hopkins University, School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.3233/CBM-2011-0169DOI Listing
July 2012

LARP7 is a potential tumor suppressor gene in gastric cancer.

Lab Invest 2012 Jul 9;92(7):1013-9. Epub 2012 Apr 9.

Division of Gastroenterology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1038/labinvest.2012.59DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446825PMC
July 2012

MicroRNAs in pathogenesis, diagnosis, and treatment of gastroesophageal cancers.

Gastroenterology 2012 Jul 10;143(1):35-47.e2. Epub 2012 May 10.

Division of Gastroenterology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1053/j.gastro.2012.05.003DOI Listing
July 2012

[32P]ATP inhibits the growth of xenografted tumors in nude mice.

Cell Cycle 2012 May 15;11(10):1878-82. Epub 2012 May 15.

Department of Medicine; The Johns Hopkins School of Medicine; Baltimore, MD USA.

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http://dx.doi.org/10.4161/cc.19955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359117PMC
May 2012

Unique patterns of CpG island methylation in inflammatory bowel disease-associated colorectal cancers.

Inflamm Bowel Dis 2012 Apr 9;18(4):641-8. Epub 2011 Aug 9.

Department of Medicine, Division of Gastroenterology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1002/ibd.21826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214229PMC
April 2012

Aberrant methylation of the PTPRO gene in peripheral blood as a potential biomarker in esophageal squamous cell carcinoma patients.

Cancer Lett 2012 Feb 12;315(2):138-44. Epub 2011 Sep 12.

Department of Integrative Chinese and Western Medicine, Cancer Hospital of Shantou University Medical College, Shantou, People's Republic of China.

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http://dx.doi.org/10.1016/j.canlet.2011.08.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248961PMC
February 2012

MicroRNA involvement in esophageal carcinogenesis.

Curr Opin Pharmacol 2011 Dec 10;11(6):612-6. Epub 2011 Oct 10.

Department of Internal Medicine, Greater Baltimore Medical Center, Baltimore, MD, United States.

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http://dx.doi.org/10.1016/j.coph.2011.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225645PMC
December 2011

Polo-like kinase 1 regulates cell proliferation and is targeted by miR-593* in esophageal cancer.

Int J Cancer 2011 Nov 11;129(9):2134-46. Epub 2011 Mar 11.

Division of Gastroenterology, Department of Medicine and Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/ijc.25874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176391PMC
November 2011

Colorectal cancers with microsatellite instability display unique miRNA profiles.

Clin Cancer Res 2011 Oct 15;17(19):6239-49. Epub 2011 Aug 15.

Department of Internal Medicine, Division of Gastroenterology, Charles A. Sammons Cancer Center and Baylor Research Institute, Baylor University Medical Center, Dallas, Texas 75246, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-1424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186834PMC
October 2011

Novel candidate colorectal cancer biomarkers identified by methylation microarray-based scanning.

Endocr Relat Cancer 2011 Aug 4;18(4):465-78. Epub 2011 Jul 4.

Division of Gastroenterology, Department of Medicine, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, Maryland 21205, USA.

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http://erc.endocrinology-journals.org/cgi/doi/10.1530/ERC-11
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http://dx.doi.org/10.1530/ERC-11-0083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464012PMC
August 2011

MicroRNAs and epigenetics.

FEBS J 2011 May 30;278(10):1598-609. Epub 2011 Mar 30.

Department of Nanobio Drug Discovery, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.

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http://doi.wiley.com/10.1111/j.1742-4658.2011.08089.x
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http://dx.doi.org/10.1111/j.1742-4658.2011.08089.xDOI Listing
May 2011

Relation between normal rectal methylation, smoking status, and the presence or absence of colorectal adenomas.

Cancer 2010 Oct;116(19):4495-501

Division of Gastroenterology, Department of Medicine, the Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1002/cncr.25348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988654PMC
October 2010

MicroRNAs in Barrett's esophagus and esophageal adenocarcinoma.

Curr Opin Pharmacol 2009 Dec 19;9(6):727-32. Epub 2009 Sep 19.

Department of Surgery, Kyoto University Hospital, Shogoin, Kyoto City, Japan.

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http://dx.doi.org/10.1016/j.coph.2009.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794797PMC
December 2009

Screening for microsatellite instability identifies frequent 3'-untranslated region mutation of the RB1-inducible coiled-coil 1 gene in colon tumors.

PLoS One 2009 Nov 2;4(11):e7715. Epub 2009 Nov 2.

Division of Gastroenterology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0007715PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766054PMC
November 2009

Honey, I shrunk the telomere: UC speeds aging.

Inflamm Bowel Dis 2009 Sep;15(9):1432-3

Department of Medicine Johns Hopkins University School of Medicine Baltimore, MD, USA.

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https://academic.oup.com/ibdjournal/article/15/9/1432-1433/4
Publisher Site
http://dx.doi.org/10.1002/ibd.20887DOI Listing
September 2009

Epigenetic events in gastrointestinal cancer.

Am J Gastroenterol 2009 Aug;104(8):1910-2

Division of Gastroenterology and Hepatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1038/ajg.2008.145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988650PMC
August 2009

The miR-106b-25 polycistron, activated by genomic amplification, functions as an oncogene by suppressing p21 and Bim.

Gastroenterology 2009 May;136(5):1689-700

Division of Gastroenterology, Department of Medicine, The Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland 21287, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887605PMC
http://dx.doi.org/10.1053/j.gastro.2009.02.002DOI Listing
May 2009

Hypermethylation of the somatostatin promoter is a common, early event in human esophageal carcinogenesis.

Cancer 2008 Jan;112(1):43-9

Division of Gastroenterology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1002/cncr.23135DOI Listing
January 2008

Hypermethylation of the AKAP12 promoter is a biomarker of Barrett's-associated esophageal neoplastic progression.

Cancer Epidemiol Biomarkers Prev 2008 Jan;17(1):111-7

Division of Gastroenterology, Department of Medicine, Johns Hopkins University School of Medicine, 1503 East Jefferson Street, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-07-0407DOI Listing
January 2008

Hypermethylation of tachykinin-1 is a potential biomarker in human esophageal cancer.

Clin Cancer Res 2007 Nov;13(21):6293-300

Division of Gastroenterology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-0818DOI Listing
November 2007