Publications by authors named "Stephen J Forman"

100Publications

Systemic Anti-PD-1 Immunotherapy Results in PD-1 Blockade on T Cells in the Cerebrospinal Fluid.

JAMA Oncol 2020 Oct 8. Epub 2020 Oct 8.

Department of Hematology and Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratories, City of Hope Beckman Research Institute and Comprehensive Cancer Center, Duarte, California.

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http://dx.doi.org/10.1001/jamaoncol.2020.4508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545351PMC
October 2020

Effective combination immunotherapy using oncolytic viruses to deliver CAR targets to solid tumors.

Sci Transl Med 2020 Sep;12(559)

Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1126/scitranslmed.aaz1863DOI Listing
September 2020

Outcome of Allogeneic Hematopoietic Cell Transplantation after Venetoclax and Hypomethylating Agent Therapy for Acute Myelogenous Leukemia.

Biol Blood Marrow Transplant 2020 Dec 29;26(12):e322-e327. Epub 2020 Aug 29.

Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope Medical Center, Duarte, California. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2020.08.027DOI Listing
December 2020

Retreatment with venetoclax and hypomethylating agents among AML patients who have relapsed after initial response and subsequent interruption of therapy.

Leuk Lymphoma 2020 Aug 19:1-2. Epub 2020 Aug 19.

Gehr Family Center for Leukemia Research, Department of Hematology and Hematopoietic Cell Transplantation, City of Hope Medical Center, Duarte, CA, USA.

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http://dx.doi.org/10.1080/10428194.2020.1808213DOI Listing
August 2020

Venetoclax and hypomethylating agents in FLT3-mutated acute myeloid leukemia.

Am J Hematol 2020 Jul 6. Epub 2020 Jul 6.

Department of Hematology and Hematopoietic Cell Transplantation, City of Hope Medical Center, Gehr Family Center for Leukemia Research, Duarte, California, USA.

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http://dx.doi.org/10.1002/ajh.25929DOI Listing
July 2020

Antitumor efficacy of BAFF-R targeting CAR T cells manufactured under clinic-ready conditions.

Cancer Immunol Immunother 2020 Oct 25;69(10):2139-2145. Epub 2020 May 25.

Toni Stephenson Lymphoma Center, Department of Hematology and Hematopoietic Cell Transplantation, Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA.

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http://dx.doi.org/10.1007/s00262-020-02614-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511472PMC
October 2020

Developing and Monitoring a Standard-of-Care Chimeric Antigen Receptor (CAR) T Cell Clinical Quality and Regulatory Program.

Biol Blood Marrow Transplant 2020 Aug 19;26(8):1386-1393. Epub 2020 May 19.

Department of Hematology T Cell Therapeutics Research Laboratory, City of Hope Medical Center, Duarte, California; Department of Hematology, The Hematologic Malignancies and Stem Cell Transplantation Institute, City of Hope National Medical Center, Duarte, California. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2020.03.021DOI Listing
August 2020

Long-Term Outcomes of Allogeneic Hematopoietic Cell Transplant with Fludarabine and Melphalan Conditioning and Tacrolimus/Sirolimus as Graft-versus-Host Disease Prophylaxis in Patients with Acute Lymphoblastic Leukemia.

Biol Blood Marrow Transplant 2020 Aug 19;26(8):1425-1432. Epub 2020 May 19.

Department of Hematology and HCT, City of Hope, Duarte, California; Department of Computational Quantitative Medicine/BRI, City of Hope, Duarte, California. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2020.04.015DOI Listing
August 2020

The efficacy of venetoclax and hypomethylating agents in acute myeloid leukemia with extramedullary involvement.

Leuk Lymphoma 2020 08 19;61(8):2020-2023. Epub 2020 Mar 19.

Gehr Family Center for Leukemia Research, Department of Hematology and Hematopoietic Cell Transplantation, City of Hope Medical Center, Duarte, CA, USA.

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http://dx.doi.org/10.1080/10428194.2020.1742908DOI Listing
August 2020

Clinical and Genetic Risk Prediction of Cognitive Impairment After Blood or Marrow Transplantation for Hematologic Malignancy.

J Clin Oncol 2020 Apr 21;38(12):1312-1321. Epub 2020 Feb 21.

Institute for Cancer Outcomes and Survivorship, School of Medicine, University of Alabama at Birmingham, Birmingham, AL.

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http://dx.doi.org/10.1200/JCO.19.01085DOI Listing
April 2020

How I treat adults with advanced acute lymphoblastic leukemia eligible for CD19-targeted immunotherapy.

Blood 2020 03;135(11):804-813

Gehr Family Center for Leukemia Research, Department of Hematology and Hematopoietic Cell Transplantation, City of Hope Medical Center, Duarte, CA.

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http://dx.doi.org/10.1182/blood.2019002132DOI Listing
March 2020

Massively-Parallelized, Deterministic Mechanoporation for Intracellular Delivery.

Nano Lett 2020 02 28;20(2):860-867. Epub 2019 Oct 28.

Department of Bioengineering , University of California - Riverside , Riverside , California 92521 , United States.

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http://dx.doi.org/10.1021/acs.nanolett.9b03175DOI Listing
February 2020

Influence of donor KIR genotypes on reduced relapse risk in acute myelogenous leukemia after hematopoietic stem cell transplantation in patients with CMV reactivation.

Leuk Res 2019 12 28;87:106230. Epub 2019 Sep 28.

Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA, United States.

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http://dx.doi.org/10.1016/j.leukres.2019.106230DOI Listing
December 2019

Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer.

Cell Stem Cell 2019 10 5;25(4):542-557.e9. Epub 2019 Sep 5.

Department of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2019.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018522PMC
October 2019

Venetoclax and hypomethylating agents in TP53-mutated acute myeloid leukaemia.

Br J Haematol 2019 10 22;187(2):e45-e48. Epub 2019 Aug 22.

Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA.

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http://dx.doi.org/10.1111/bjh.16166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786919PMC
October 2019

Allogeneic Stem Cell Transplantation Provides Durable Remission in Patients with Primary Mediastinal Large B Cell Lymphoma.

Biol Blood Marrow Transplant 2019 12 5;25(12):2383-2387. Epub 2019 Aug 5.

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Medical Oncology Division, University of Washington, Seattle, Washington.

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http://dx.doi.org/10.1016/j.bbmt.2019.07.041DOI Listing
December 2019

The feasibility of venetoclax and decitabine in therapy-related acute myeloid leukemia with concurrent advanced non-hematological malignancies.

Leuk Res 2019 09 30;84:106196. Epub 2019 Jul 30.

Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01452126193014
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http://dx.doi.org/10.1016/j.leukres.2019.106196DOI Listing
September 2019

Favorable outcomes for allogeneic hematopoietic cell transplantation in elderly patients with NPM1-mutated and FLT3-ITD-negative acute myeloid leukemia.

Bone Marrow Transplant 2020 02 14;55(2):473-475. Epub 2019 May 14.

Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA.

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http://dx.doi.org/10.1038/s41409-019-0553-xDOI Listing
February 2020

IL15 Enhances CAR-T Cell Antitumor Activity by Reducing mTORC1 Activity and Preserving Their Stem Cell Memory Phenotype.

Cancer Immunol Res 2019 05 19;7(5):759-772. Epub 2019 Mar 19.

Department of Hematology and Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratory, City of Hope, Duarte, California.

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http://dx.doi.org/10.1158/2326-6066.CIR-18-0466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687561PMC
May 2019

In Vitro Tumor Cell Rechallenge For Predictive Evaluation of Chimeric Antigen Receptor T Cell Antitumor Function.

J Vis Exp 2019 02 27(144). Epub 2019 Feb 27.

Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratory, City of Hope Beckman Research Institute and Medical Center;

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http://dx.doi.org/10.3791/59275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719706PMC
February 2019

Acute Lymphoblastic Leukemia in the Older Adult.

J Oncol Pract 2019 02;15(2):67-75

1 Gehr Family Leukemia Research Center, City of Hope National Medical Center, Duarte, CA.

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http://dx.doi.org/10.1200/JOP.18.00271DOI Listing
February 2019

Post-Allogeneic Hematopoietic Stem Cell Transplantation Eculizumab as Prophylaxis Against Hemolysis and Thrombosis for Patients with Hematologic Disorders Associated with Paroxysmal Nocturnal Hemoglobinuria Clones.

Biol Blood Marrow Transplant 2019 05 29;25(5):e183-e185. Epub 2019 Jan 29.

Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, California; Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, California.

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http://dx.doi.org/10.1016/j.bbmt.2019.01.025DOI Listing
May 2019

The Bcl-2 inhibitor venetoclax inhibits Nrf2 antioxidant pathway activation induced by hypomethylating agents in AML.

J Cell Physiol 2019 08 8;234(8):14040-14049. Epub 2019 Jan 8.

Gehr Family Center for Leukemia Research, Hematology Malignancies and Stem Cell Transplantation Institute, City of Hope Medical Center, Duarte, California.

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http://dx.doi.org/10.1002/jcp.28091DOI Listing
August 2019

Adults with Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia: Considerations for Allogeneic Hematopoietic Cell Transplantation in First Complete Remission.

Biol Blood Marrow Transplant 2019 02 5;25(2):e41-e45. Epub 2018 Oct 5.

Department of Hematology and Hematopoietic cell transplantation, City of Hope Medical Center, Duarte, California.

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https://linkinghub.elsevier.com/retrieve/pii/S10838791183060
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http://dx.doi.org/10.1016/j.bbmt.2018.09.041DOI Listing
February 2019

Outcomes of Patients with Recurrent and Refractory Lymphoma Undergoing Allogeneic Hematopoietic Cell Transplantation with BEAM Conditioning and Sirolimus- and Tacrolimus-Based GVHD Prophylaxis.

Biol Blood Marrow Transplant 2019 02 15;25(2):287-292. Epub 2018 Sep 15.

Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, California; Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, California. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10838791183056
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http://dx.doi.org/10.1016/j.bbmt.2018.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502508PMC
February 2019

Acute lymphoblastic leukemia as a clonally unrelated second primary malignancy after multiple myeloma.

Leukemia 2019 01 19;33(1):266-270. Epub 2018 Jul 19.

The Judy and Bernard Briskin Center for Multiple Myeloma Research, City of Hope, Duarte, CA, USA.

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http://dx.doi.org/10.1038/s41375-018-0213-yDOI Listing
January 2019

Regulation of miR-34b/c-targeted gene expression program by SUMOylation.

Nucleic Acids Res 2018 08;46(14):7108-7123

Department of Molecular Medicine, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1093/nar/gky484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101486PMC
August 2018

Glioblastoma-targeted CD4+ CAR T cells mediate superior antitumor activity.

JCI Insight 2018 05 17;3(10). Epub 2018 May 17.

Department of Hematology and Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratory, and.

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https://insight.jci.org/articles/view/99048
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http://dx.doi.org/10.1172/jci.insight.99048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012522PMC
May 2018

PET of Adoptively Transferred Chimeric Antigen Receptor T Cells with Zr-Oxine.

J Nucl Med 2018 10 4;59(10):1531-1537. Epub 2018 May 4.

Department of Molecular Immunology, Beckman Research Institute, City of Hope Medical Center, Duarte, California

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http://dx.doi.org/10.2967/jnumed.117.206714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167529PMC
October 2018

A Future for Autologous Hematopoietic Stem Cell Transplantation in Type 1 Diabetes.

Front Immunol 2018 6;9:690. Epub 2018 Apr 6.

Department of Diabetes Immunology, Diabetes & Metabolism Research Institute, Beckman Research Institute at the City of Hope, Duarte, CA, United States.

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http://dx.doi.org/10.3389/fimmu.2018.00690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904498PMC
June 2019

Cognitive Functioning After Hematopoietic Cell Transplantation for Hematologic Malignancy: Results From a Prospective Longitudinal Study.

J Clin Oncol 2018 02 18;36(5):463-475. Epub 2017 Dec 18.

Noha Sharafeldin, Liton Francisco, and Smita Bhatia, University of Alabama at Birmingham, Birmingham, AL; and Alysia Bosworth, Sunita K. Patel, Yanjun Chen, Emily Morse, Molly Mather, Canlan Sun, Stephen J. Forman, and F. Lennie Wong, City of Hope, Duarte, CA.

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http://dx.doi.org/10.1200/JCO.2017.74.2270DOI Listing
February 2018

Prevalence of anthracycline-related cardiac dysfunction in long-term survivors of adult-onset lymphoma.

Cancer 2018 02 7;124(4):850-857. Epub 2017 Nov 7.

Institute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Birmingham, Alabama.

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http://dx.doi.org/10.1002/cncr.31110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801059PMC
February 2018

Optimization of IL13Rα2-Targeted Chimeric Antigen Receptor T Cells for Improved Anti-tumor Efficacy against Glioblastoma.

Mol Ther 2018 01 5;26(1):31-44. Epub 2017 Oct 5.

Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratory, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1016/j.ymthe.2017.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763077PMC
January 2018

How I treat patients with HIV-related hematological malignancies using hematopoietic cell transplantation.

Blood 2017 11 7;130(18):1976-1984. Epub 2017 Sep 7.

Hematological Malignancies and Hematopoietic Stem Cell Transplantation Institute, City of Hope, Duarte, CA.

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http://dx.doi.org/10.1182/blood-2017-04-551606DOI Listing
November 2017

Stabilization of the c-Myc Protein by CAMKIIγ Promotes T Cell Lymphoma.

Cancer Cell 2017 07;32(1):115-128.e7

Molecular and Cellular Biology of Cancer Program & Department of Diabetes Complications and Metabolism, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA; Irell & Manella Graduate School of Biological Sciences, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15356108173025
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http://dx.doi.org/10.1016/j.ccell.2017.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552197PMC
July 2017

Antileukemic activity and cellular effects of the antimalarial agent artesunate in acute myeloid leukemia.

Leuk Res 2017 08 10;59:124-135. Epub 2017 May 10.

Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA 91010, USA; Gehr Family Center for Leukemia Research City of Hope Medical Center, Duarte, CA 91010, USA. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2017.05.007DOI Listing
August 2017