Stephen Hearty

Stephen Hearty

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Stephen Hearty

Stephen Hearty

Publications by authors named "Stephen Hearty"

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28Publications

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Decoding Selection Bias Imparted by Unpaired Cysteines: a Tug of War Between Expression and Affinity.

Appl Biochem Biotechnol 2018 Jul 12;185(3):778-785. Epub 2018 Jan 12.

Biomedical Diagnostics Institute, National Centre for Sensor Research, Dublin City University, Glasnevin, Dublin 9, Ireland.

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July 2018

Measuring Protein-Protein Interactions Using Biacore.

Methods Mol Biol 2017 ;1485:339-354

Biomedical Diagnostics Institute, Dublin City University, Dublin 9, Ireland.

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January 2018

Measuring Antibody-Antigen Binding Kinetics Using Surface Plasmon Resonance.

Methods Mol Biol 2018 ;1827:421-455

School of Biotechnology, Dublin City University, Dublin, Ireland.

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January 2018

Facile domain rearrangement abrogates expression recalcitrance in a rabbit scFv.

Appl Microbiol Biotechnol 2015 Mar 24;99(6):2693-703. Epub 2014 Dec 24.

Biomedical Diagnostics Institute, National Centre for Sensor Research, Glasnevin, Dublin City University, Dublin 9, Ireland.

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March 2015

Reconciling the structural attributes of avian antibodies.

J Biol Chem 2014 May 15;289(22):15384-92. Epub 2014 Apr 15.

From the Department of Biochemistry and Molecular Biology, Faculty of Medicine, Nursing and Health Science, Monash University, Melbourne, Victoria 3800, Australia,

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May 2014

A highly stable, sensitive, regenerable and rapid immunoassay for detecting aflatoxin B1 in corn incorporating covalent AFB1 immobilization and a recombinant Fab antibody.

Talanta 2013 Oct 14;115:329-35. Epub 2013 May 14.

Applied Biochemistry Group (ABG), School of Biotechnology, Dublin City University, Dublin 9, Ireland. Electronic address:

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October 2013

Measuring antibody-antigen binding kinetics using surface plasmon resonance.

Methods Mol Biol 2012 ;907:411-42

Biomedical Diagnostics Institute, Dublin City University, Dublin, Ireland.

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December 2012

Exploiting recombinant antibodies in point-of-care (POC) diagnostics: the combinatorial advantage.

Bioeng Bugs 2011 May-Jun;2(3):182-6. Epub 2011 May 1.

Biomedical Diagnostics Institute, National Centre for Sensor Research, School of Biotechnology, Dublin City University, Dublin, Ireland.

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November 2011

A high-affinity recombinant antibody permits rapid and sensitive direct detection of myeloperoxidase.

Anal Biochem 2011 Mar 23;410(1):1-6. Epub 2010 Oct 23.

Biomedical Diagnostics Institute (BDI), Dublin City University, Dublin 9, Ireland.

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March 2011

Measuring protein-protein interactions using Biacore.

Methods Mol Biol 2011 ;681:403-18

School of Biotechnology and Biomedical Diagnostics Institute, Dublin City University, Dublin, Ireland.

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February 2011

Highly sensitive recombinant antibodies capable of reliably differentiating heart-type fatty acid binding protein from noncardiac isoforms.

Anal Biochem 2010 Dec 7;407(2):165-71. Epub 2010 Aug 7.

Biomedical Diagnostics Institute, National Centre for Sensor Research, Dublin City University, Dublin 9, Ireland.

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December 2010

Surface plasmon resonance for vaccine design and efficacy studies: recent applications and future trends.

Expert Rev Vaccines 2010 Jun;9(6):645-64

Biomedical Diagnostics Institute, Dublin City University, Dublin 9, Ireland.

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June 2010

Cardiac biomarkers and the case for point-of-care testing.

Clin Biochem 2009 May 7;42(7-8):549-61. Epub 2009 Feb 7.

Biomedical Diagnostics Institute, Dublin City University, Dublin, Ireland.

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May 2009

Antibody production, design and use for biosensor-based applications.

Semin Cell Dev Biol 2009 Feb 4;20(1):10-26. Epub 2009 Feb 4.

Biomedical Diagnostics Institute, National Centre for Sensor Research, School of Biotechnology, Dublin City University, Dublin 9, Ireland.

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February 2009

Helicobacter pylori lipopolysaccharide interacts with TFF1 in a pH-dependent manner.

Gastroenterology 2008 Dec 3;135(6):2043-54, 2054.e1-2. Epub 2008 Sep 3.

University College Dublin School of Medicine and Medical Science, The Children's Research Centre, Our Lady's Children's Hospital, Dublin, Ireland.

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December 2008

High throughput ranking of recombinant avian scFv antibody fragments from crude lysates using the Biacore A100.

J Immunol Methods 2007 Jun 15;323(2):172-9. Epub 2007 May 15.

Biomedical Diagnostics Institute, Dublin City University, Dublin 9, Ireland.

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June 2007

Detection of fungal spores using a generic surface plasmon resonance immunoassay.

Biosens Bioelectron 2007 May 18;22(11):2724-9. Epub 2006 Dec 18.

Danish Institute of Agricultural Sciences, Department of Integrated Pest Management, DK-4200 Slagelse, Denmark.

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May 2007

Monoclonal antibodies for the detection of Puccinia striiformis urediniospores.

Mycol Res 2007 Mar 9;111(Pt 3):332-8. Epub 2007 Mar 9.

Danish Institute of Agricultural Sciences, Department of Integrated Pest Management, DK-4200 Slagelse, Denmark.

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March 2007

Rapid analysis of coumarins using surface plasmon resonance.

J AOAC Int 2006 May-Jun;89(3):884-92

Dublin City University, National Centre for Sensor Research, School of Biotechnology, Dublin 9, Ireland.

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November 2006

Production, characterisation and potential application of a novel monoclonal antibody for rapid identification of virulent Listeria monocytogenes.

J Microbiol Methods 2006 Aug 2;66(2):294-312. Epub 2006 Feb 2.

School of Biotechnology, Dublin City University, Dublin 9, Ireland.

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August 2006

The development of rapid fluorescence-based immunoassays, using quantum dot-labelled antibodies for the detection of Listeria monocytogenes cell surface proteins.

Int J Biol Macromol 2006 Aug 4;39(1-3):127-34. Epub 2006 Apr 4.

School of Biotechnology & National Centre for Sensor Research, Dublin City University, Glasnevin, Dublin 9, Ireland.

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August 2006

Development of a surface plasmon resonance-based immunoassay for Listeria monocytogenes.

J Food Prot 2005 Apr;68(4):728-35

School of Biotechnology and National Centre for Sensor Research, Dublin City University, Dublin 9, Ireland.

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April 2005

A generic approach for the detection of whole Listeria monocytogenes cells in contaminated samples using surface plasmon resonance.

Biosens Bioelectron 2004 May;19(10):1331-5

School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.

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May 2004