Publications by authors named "Stephen H Friend"

46Publications

CANCER. The cancer predisposition revolution.

Science 2016 May;352(6289):1052-3

Sage Bionetworks, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1126/science.aag0832DOI Listing
May 2016

The Use of Smartphones for Health Research.

Acad Med 2017 02;92(2):157-160

E.R. Dorsey is professor, Department of Neurology, and director, Center for Human Experimental Technologies (CHET), University of Rochester Medical Center, Rochester, New York. Y.F. Chan is assistant professor, Department of Genetics and Genomic Sciences and Department of Emergency Medicine, and director of digital health, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York. M.V. McConnell is professor, Department of Medicine, and director of cardiovascular health innovation, Stanford University School of Medicine, Stanford, California. S.Y. Shaw is assistant professor, Department of Medicine, and cofounder and codirector, Center for Assessment Technology and Continuous Health (CATCH), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. A.D. Trister is senior physician, Sage Bionetworks, Seattle, Washington. S.H. Friend is president, cofounder, and director, Sage Bionetworks, Seattle, Washington.

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http://dx.doi.org/10.1097/ACM.0000000000001205DOI Listing
February 2017

Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.

Authors:
Genevera I Allen Nicola Amoroso Catalina Anghel Venkat Balagurusamy Christopher J Bare Derek Beaton Roberto Bellotti David A Bennett Kevin L Boehme Paul C Boutros Laura Caberlotto Cristian Caloian Frederick Campbell Elias Chaibub Neto Yu-Chuan Chang Beibei Chen Chien-Yu Chen Ting-Ying Chien Tim Clark Sudeshna Das Christos Davatzikos Jieyao Deng Donna Dillenberger Richard J B Dobson Qilin Dong Jimit Doshi Denise Duma Rosangela Errico Guray Erus Evan Everett David W Fardo Stephen H Friend Holger Fröhlich Jessica Gan Peter St George-Hyslop Satrajit S Ghosh Enrico Glaab Robert C Green Yuanfang Guan Ming-Yi Hong Chao Huang Jinseub Hwang Joseph Ibrahim Paolo Inglese Anandhi Iyappan Qijia Jiang Yuriko Katsumata John S K Kauwe Arno Klein Dehan Kong Roland Krause Emilie Lalonde Mario Lauria Eunjee Lee Xihui Lin Zhandong Liu Julie Livingstone Benjamin A Logsdon Simon Lovestone Tsung-Wei Ma Ashutosh Malhotra Lara M Mangravite Taylor J Maxwell Emily Merrill John Nagorski Aishwarya Namasivayam Manjari Narayan Mufassra Naz Stephen J Newhouse Thea C Norman Ramil N Nurtdinov Yen-Jen Oyang Yudi Pawitan Shengwen Peng Mette A Peters Stephen R Piccolo Paurush Praveen Corrado Priami Veronica Y Sabelnykova Philipp Senger Xia Shen Andrew Simmons Aristeidis Sotiras Gustavo Stolovitzky Sabina Tangaro Andrea Tateo Yi-An Tung Nicholas J Tustison Erdem Varol George Vradenburg Michael W Weiner Guanghua Xiao Lei Xie Yang Xie Jia Xu Hojin Yang Xiaowei Zhan Yunyun Zhou Fan Zhu Hongtu Zhu Shanfeng Zhu

Alzheimers Dement 2016 06 11;12(6):645-53. Epub 2016 Apr 11.

School of Computer Science, Fudan University, Shanghai, Shanghai, China; Shanghai Key Lab of Intelligent Information Processing, Fudan University, Shanghai, Shanghai, China; Centre for Computational Systems Biology, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1016/j.jalz.2016.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474755PMC
June 2016

First, design for data sharing.

Nat Biotechnol 2016 Apr;34(4):377-9

Sage Bionetworks, Seattle, Washington, USA.

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http://dx.doi.org/10.1038/nbt.3516DOI Listing
April 2016

Smartphones as new tools in the management and understanding of Parkinson's disease.

NPJ Parkinsons Dis 2016 3;2:16006. Epub 2016 Mar 3.

Sage Bionetworks, Seattle, WA, USA.

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http://dx.doi.org/10.1038/npjparkd.2016.6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516584PMC
March 2016

PERSONALIZED HYPOTHESIS TESTS FOR DETECTING MEDICATION RESPONSE IN PARKINSON DISEASE PATIENTS USING iPHONE SENSOR DATA.

Pac Symp Biocomput 2016 ;21:273-84

Sage Bionetworks, 1100 Fairview Avenue North, Seattle, Washington 98109, USA*Corresponding author.,

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October 2016

App-enabled trial participation: Tectonic shift or tepid rumble?

Authors:
Stephen H Friend

Sci Transl Med 2015 Jul;7(297):297ed10

Stephen H. Friend is the president of Sage Bionetworks, Seattle, WA 98109, USA. E-mail:

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http://dx.doi.org/10.1126/scitranslmed.aab1206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440077PMC
July 2015

Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection.

Nat Methods 2015 Jul 18;12(7):623-30. Epub 2015 May 18.

1] Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada. [2] Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. [3] Department of Pharmacology &Toxicology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/nmeth.3407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856034PMC
July 2015

Translational genomics. Clues from the resilient.

Science 2014 May;344(6187):970-2

Icahn School of Medicine at Mount Sinai, Department of Genetics and Genomic Sciences and the Icahn Institute for Genomics and Multiscale Biology, New York, NY 10029, USA.

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http://dx.doi.org/10.1126/science.1255648DOI Listing
May 2014

Cancer. Potential of the synthetic lethality principle.

Science 2013 Nov;342(6160):809-11

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.

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http://dx.doi.org/10.1126/science.1244669DOI Listing
November 2013

Metcalfe's law and the biology information commons.

Nat Biotechnol 2013 Apr;31(4):297-303

Sage Bionetworks, Seattle, Washington, USA.

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http://dx.doi.org/10.1038/nbt.2555DOI Listing
April 2013

Point: Are we prepared for the future doctor visit?

Nat Biotechnol 2011 Mar;29(3):215-8

Sage Bionetworks, Seattle, Washington, USA.

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http://dx.doi.org/10.1038/nbt.1794DOI Listing
March 2011

Predictive, personalized, preventive, participatory (P4) cancer medicine.

Nat Rev Clin Oncol 2011 03;8(3):184-7

Institute for Systems Biology, 1441 North 34th Street, Seattle, WA 98103, USA.

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http://dx.doi.org/10.1038/nrclinonc.2010.227DOI Listing
March 2011

Opening up to precompetitive collaboration.

Sci Transl Med 2010 Oct;2(52):52cm26

AltshulerGray, 61 Dean Road, Brookline, MA 02445, USA.

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http://dx.doi.org/10.1126/scitranslmed.3001515DOI Listing
October 2010

Something in common.

Authors:
Stephen H Friend

Sci Transl Med 2010 Jul;2(40):40ed6

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http://stm.sciencemag.org/cgi/doi/10.1126/scitranslmed.30012
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http://dx.doi.org/10.1126/scitranslmed.3001280DOI Listing
July 2010

A network view of disease and compound screening.

Nat Rev Drug Discov 2009 04;8(4):286-95

Eric E. Schadt is at Rosetta Inpharmatics, LLC, Merck & Co., Inc., 401 Terry Avenue North, Seattle, Washington 98109, USA.

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http://www.nature.com/articles/nrd2826
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http://dx.doi.org/10.1038/nrd2826DOI Listing
April 2009

Accelerating drug discovery: Open source cancer cell biology?

Cancer Cell 2006 Nov;10(5):349-51

Merck Research Laboratories, Merck & Co, Inc., Upper Gwynedd, Pennsylvania 19454, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S153561080600317
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http://dx.doi.org/10.1016/j.ccr.2006.10.011DOI Listing
November 2006

Cancer biomarkers--an invitation to the table.

Science 2006 May;312(5777):1165-8

H. Lee Moffitt Cancer Center, University of South Florida, Tampa, FL 33613, USA.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1125948
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http://dx.doi.org/10.1126/science.1125948DOI Listing
May 2006

How molecular profiling could revolutionize drug discovery.

Nat Rev Drug Discov 2005 Apr;4(4):345-50

GHC Technologies, Inc., 505 Coast Boulevard South, Suite 309, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/nrd1696DOI Listing
April 2005

Signatures of environmental exposures using peripheral leukocyte gene expression: tobacco smoke.

Cancer Epidemiol Biomarkers Prev 2004 Mar;13(3):445-53

Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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March 2004

Alfred Knudson: the importance of a visionary who enables scientists.

Authors:
Stephen H Friend

Genes Chromosomes Cancer 2003 Dec;38(4):326-8

Merck Research Laboratories, Merck & Company, West Point, Pennsylvania, USA.

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http://dx.doi.org/10.1002/gcc.10257DOI Listing
December 2003

Toxicogenomics and drug discovery: will new technologies help us produce better drugs?

Nat Rev Drug Discov 2002 01;1(1):84-8

Rosetta Inpharmatics, 12040 115th Avenue NE, Kirkland, Washington 98034, USA.

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http://www.nature.com/articles/nrd710
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http://dx.doi.org/10.1038/nrd710DOI Listing
January 2002

The magic of microarrays.

Sci Am 2002 Feb;286(2):44-9, 53

Rosetta Inpharmatics, Kirkland, Wash., USA.

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http://dx.doi.org/10.1038/scientificamerican0202-44DOI Listing
February 2002