Stephen G Matthews

Stephen G Matthews

UNVERIFIED PROFILE

Are you Stephen G Matthews?   Register this Author

Register author
Stephen G Matthews

Stephen G Matthews

Publications by authors named "Stephen G Matthews"

Are you Stephen G Matthews?   Register this Author

100Publications

1268Reads

13Profile Views

Maternal malnutrition impacts placental morphology and transporter expression: an origin for poor offspring growth.

J Nutr Biochem 2020 Apr 8;78:108329. Epub 2020 Jan 8.

Department of Physiology, University of Toronto, Toronto, Ontario, Canada; Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, Brazil.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jnutbio.2019.108329DOI Listing
April 2020

Parental adversity: Impact across generations.

Neurosci Biobehav Rev 2020 Mar 17. Epub 2020 Mar 17.

Department of Physiology, Obstetrics & Gynaecology and Medicine, University of Toronto, Toronto, Ontario, Canada and Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neubiorev.2020.03.016DOI Listing
March 2020

Developmental programming of the HPA axis and related behaviours: epigenetic mechanisms.

J Endocrinol 2019 07;242(1):T69-T79

Department of Physiology, University of Toronto, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1530/JOE-19-0057DOI Listing
July 2019

Prenatal programming of stress responsiveness and behaviours: Progress and perspectives.

J Neuroendocrinol 2019 03 1;31(3):e12674. Epub 2019 Feb 1.

Departments of Physiology, Obstetrics and Gynaecology and Medicine, University of Toronto, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jne.12674DOI Listing
March 2019

Genome-wide epigenetic signatures of childhood adversity in early life: Opportunities and challenges.

J Dev Orig Health Dis 2019 02 12;10(1):65-72. Epub 2019 Feb 12.

1Department of Physiology,University of Toronto,Toronto,ON,Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S2040174418000843DOI Listing
February 2019

Glucocorticoids modulate multidrug resistance transporters in the first trimester human placenta.

J Cell Mol Med 2018 07 24;22(7):3652-3660. Epub 2018 Apr 24.

Department of Physiology, University of Toronto, Toronto, ON, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jcmm.13646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010777PMC
July 2018

The DNA methylation landscape of enhancers in the guinea pig hippocampus.

Epigenomics 2018 04 4;10(4):349-365. Epub 2018 Apr 4.

Department of Pharmacology & Therapeutics, Sackler Program for Epigenetics & Psychobiology, McGill University, Montreal, Quebec H3G 1Y6, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/epi-2017-0064DOI Listing
April 2018

Prenatal Stress, Glucocorticoids, and Developmental Programming of the Stress Response.

Endocrinology 2018 01;159(1):69-82

Department of Physiology, University of Toronto, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2017-00896DOI Listing
January 2018

Automated tracking to measure behavioural changes in pigs for health and welfare monitoring.

Sci Rep 2017 12 14;7(1):17582. Epub 2017 Dec 14.

Agriculture, School of Natural and Environmental Sciences, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-017-17451-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730557PMC
December 2017

Nurturing care: promoting early childhood development.

Lancet 2017 01 4;389(10064):91-102. Epub 2016 Oct 4.

Center of Excellence in Women and Child Health, The Aga Khan University, Karachi, Pakistan; Center for Global Child Health, The Hospital for Sick Children, Toronto, ON, Canada.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01406736163139
Publisher Site
http://dx.doi.org/10.1016/S0140-6736(16)31390-3DOI Listing
January 2017

Characterization and novel analyses of acute stress response patterns in a population-based cohort of young adults: influence of gender, smoking, and BMI.

Stress 2016 3;19(2):139-50. Epub 2016 Mar 3.

a School of Women's and Infants' Health, The University of Western Australia , Perth , WA , Australia .

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/10253890.2016.1146672DOI Listing
December 2016

Early detection of health and welfare compromises through automated detection of behavioural changes in pigs.

Vet J 2016 Nov 28;217:43-51. Epub 2016 Sep 28.

School of Agriculture, Food and Rural Development, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tvjl.2016.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5110645PMC
November 2016

Reply to Commentary Letter by Dr. Melvin Khee Shing Leow.

J Steroid Biochem Mol Biol 2016 10 28;163:213. Epub 2016 Jul 28.

Department of Physiology, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jsbmb.2016.07.013DOI Listing
October 2016

P-glycoprotein expression and localization in the rat uterus throughout gestation and labor.

Reproduction 2016 09 22;152(3):195-204. Epub 2016 Jun 22.

Lunenfeld-Tanenbaum Research InstituteMount Sinai Hospital, Toronto, Ontario, Canada Department of Obstetrics & GynecologyUniversity of Toronto, Toronto, Ontario, Canada Department of PhysiologyUniversity of Toronto, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1530/REP-16-0161DOI Listing
September 2016

High reactivity of the cortisol awakening response predicts positive treatment outcome in heterogeneous depressed patients completing an alternate milieu inpatient program.

Gen Hosp Psychiatry 2015 Nov-Dec;37(6):601-5. Epub 2015 Jun 10.

Centre for Addiction and Mental Health, Toronto, Ontario, Canada M6J 1H4; University of Toronto Department of Psychiatry, Toronto, Ontario, Canada M5S 2J7; University of Toronto Department of Physiology, Toronto, Ontario, Canada, M5S 2J7; Institute of Medical Science, Toronto, Ontario, Canada M5S 2J7.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.genhosppsych.2015.06.006DOI Listing
August 2016

Astrocyte-mediated regulation of multidrug resistance p-glycoprotein in fetal and neonatal brain endothelial cells: age-dependent effects.

Physiol Rep 2016 08 22;4(16). Epub 2016 Aug 22.

Department of Physiology, Faculty of Medicine University of Toronto, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14814/phy2.12853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002904PMC
August 2016

Programming of stress pathways: A transgenerational perspective.

J Steroid Biochem Mol Biol 2016 06 22;160:175-80. Epub 2015 Oct 22.

Department of Physiology, University of Toronto, Canada; Department of Obstetrics & Gynaecology and Medicine, University of Toronto, Canada; Fraser Mustard Institute for Human Development, University of Toronto, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jsbmb.2015.10.008DOI Listing
June 2016

Hypothalamic-pituitary-adrenal axis activity under resting conditions and cardiovascular risk factors in adolescents.

Psychoneuroendocrinology 2016 Apr 9;66:118-24. Epub 2016 Jan 9.

School of Medicine and Pharmacology, University of Western Australia, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.psyneuen.2016.01.002DOI Listing
April 2016

Glucocorticoids modify effects of TGF-β1 on multidrug resistance in the fetal blood-brain barrier.

Growth Factors 2016 02 28;34(1-2):33-41. Epub 2016 Apr 28.

a Department of Physiology , University of Toronto , Toronto , ON , Canada .

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/08977194.2016.1162163DOI Listing
February 2016

The ontogeny of P-glycoprotein in the developing human blood-brain barrier: implication for opioid toxicity in neonates.

Pediatr Res 2015 Oct 18;78(4):417-21. Epub 2015 Jun 18.

Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/pr.2015.119DOI Listing
October 2015

Impact of bacterial and viral challenge on multidrug resistance in first- and third-trimester human placenta.

Am J Pathol 2015 Jun 8;185(6):1666-75. Epub 2015 May 8.

Department of Physiology, University of Toronto, Toronto, Ontario, Canada; Department of Obstetrics and Gynecology, University of Toronto, Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2015.02.013DOI Listing
June 2015

Low maternal sensitivity at 6 months of age predicts higher BMI in 48 month old girls but not boys.

Appetite 2014 Nov 15;82:97-102. Epub 2014 Jul 15.

Institute of Medical Science, University of Toronto, Toronto, ON M5S 1A8, Canada; Centre for Addition and Mental Health (CAMH), Toronto, ON M6J 1H4, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.appet.2014.07.012DOI Listing
November 2014

Synthetic glucocorticoid reduces human placental system a transport in women treated with antenatal therapy.

J Clin Endocrinol Metab 2014 Nov 8;99(11):E2226-33. Epub 2014 Aug 8.

Departments of Physiology (M.C.A., J.R.G.C., S.G.M.), Obstetrics and Gynecology (J.R.G.C., S.G.M.), and Medicine (M.C.A., J.R.G.C., S.G.M.) University of Toronto, Toronto, Ontario Canada M5A 1A8; and Maternal and Fetal Heath Research Centre (J.R.G.C., R.L.J., C.P.S.), School Institute of Human Development, Manchester Academic Health Sciences Centre, University of Manchester, St. Mary's Hospital, Central Manchester University Hospitals National Health Service Foundation Trust, Manchester M13 9WL, United Kingdom.

View Article

Download full-text PDF

Source
https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
Publisher Site
http://dx.doi.org/10.1210/jc.2014-2157DOI Listing
November 2014

The maternal adversity, vulnerability and neurodevelopment project: theory and methodology.

Can J Psychiatry 2014 Sep;59(9):497-508

Professor, McGill University, Montreal, Quebec. Associate Director, Douglas Mental Health University Institute, Montreal, Quebec; Adjunct Senior Investigator, Singapore Institute for Clinical Sciences, Singapore, Republic of Singapore.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168812PMC
http://dx.doi.org/10.1177/070674371405900906DOI Listing
September 2014

Glucocorticoids and fetal programming part 1: Outcomes.

Nat Rev Endocrinol 2014 Jul 27;10(7):391-402. Epub 2014 May 27.

Departments of Obstetrics and Gynaecology, Medicine and Physiology, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrendo.2014.73DOI Listing
July 2014

Glucocorticoids and fetal programming part 2: Mechanisms.

Nat Rev Endocrinol 2014 Jul 27;10(7):403-11. Epub 2014 May 27.

Departments of Obstetrics and Gynaecology, Medicine and Physiology, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrendo.2014.74DOI Listing
July 2014

More evidence that unnecessary antenatal treatments cause harm--reply.

JAMA Pediatr 2014 Apr;168(4):389-90

Department of Physiology, Fraser Mustard Institute of Human Development, University of Toronto, Toronto, Ontario, Canada4Department of Obstetrics and Gynaecology, Fraser Mustard Institute of Human Development, University of Toronto, Toronto, Ontario, Cana.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamapediatrics.2013.5244DOI Listing
April 2014

TGF-β1 regulation of multidrug resistance P-glycoprotein in the developing male blood-brain barrier.

Endocrinology 2014 Feb 21;155(2):475-84. Epub 2013 Nov 21.

Department of Physiology (S.B., M.I., E.B., M.J., S.G.M.), Obstetrics and Gynecology (S.G.M.), and Medicine (S.G.M.), Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada; and Department of Obstetrics and Gynecology (W.G.), and Cellular and Molecular Medicine (W.G.), Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2013-1472DOI Listing
February 2014

Adult glucocorticoid exposure leads to transcriptional and DNA methylation changes in nuclear steroid receptors in the hippocampus and kidney of mouse male offspring.

Biol Reprod 2014 Feb 27;90(2):43. Epub 2014 Feb 27.

Department of Pharmacology & Therapeutics, McGill University, Montreal, Quebec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1095/biolreprod.113.115899DOI Listing
February 2014

Effects of antenatal synthetic glucocorticoid on glucocorticoid receptor binding, DNA methylation, and genome-wide mRNA levels in the fetal male hippocampus.

Endocrinology 2013 Nov 12;154(11):4170-81. Epub 2013 Sep 12.

Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, Ontario, Canada M5S 1A8.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2013-1484DOI Listing
November 2013

Effects of sertraline and fluoxetine on p-glycoprotein at barrier sites: in vivo and in vitro approaches.

PLoS One 2013 28;8(2):e56525. Epub 2013 Feb 28.

Wisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0056525PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585317PMC
August 2013

Glucocorticoid programming of the fetal male hippocampal epigenome.

Endocrinology 2013 Mar 6;154(3):1168-80. Epub 2013 Feb 6.

Department Pharmacology & Therapeutics, McGill University, Montreal, Quebec, Canada H3G1Y6.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2012-1980DOI Listing
March 2013

Transgenerational effects of prenatal synthetic glucocorticoids on hypothalamic-pituitary-adrenal function.

Endocrinology 2012 Jul 7;153(7):3295-307. Epub 2012 May 7.

Department of Physiology, Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, Ontario, Canada M5S 1A8.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2012-1054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413075PMC
July 2012

Sertraline alters multidrug resistance phosphoglycoprotein activity in the mouse placenta and fetal blood-brain barrier.

Reprod Sci 2012 Apr;19(4):407-15

Department of Physiology, University of Toronto, Toronto, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1933719111424438DOI Listing
April 2012

Transgenerational inheritance of stress pathology.

Exp Neurol 2012 Jan 31;233(1):95-101. Epub 2011 Jan 31.

Department of Physiology, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario, M5S 1A8, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.expneurol.2011.01.009DOI Listing
January 2012

Is perinatal neuroendocrine programming involved in the developmental origins of metabolic disorders?

World J Diabetes 2011 Dec;2(12):211-6

David IW Phillips, MRC Lifecourse Epidemiology Unit, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4239/wjd.v2.i12.211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238489PMC
December 2011

Effects of chronic maternal stress on hypothalamo-pituitary-adrenal (HPA) function and behavior: no reversal by environmental enrichment.

Horm Behav 2011 Nov 31;60(5):589-98. Epub 2011 Aug 31.

Department of Physiology, Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, Ontario, Canada M5S 1A8.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yhbeh.2011.08.008DOI Listing
November 2011

Antenatal dexamethasone treatment in midgestation reduces system A-mediated transport in the late-gestation murine placenta.

Endocrinology 2011 Sep 5;152(9):3561-70. Epub 2011 Jul 5.

Department of Physiology, University of Toronto, 1 Kings College Circle, Medical Sciences Building Room 3360, Toronto, Ontario, Canada M5S 1A8.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2011-0104DOI Listing
September 2011

Glucocorticoid regulation of placental breast cancer resistance protein (Bcrp1) in the mouse.

Reprod Sci 2011 Jul 20;18(7):631-9. Epub 2011 May 20.

Department of Physiology, University of Toronto, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1933719110395399DOI Listing
July 2011

Breast cancer-resistance protein (BCRP1) in the fetal mouse brain: development and glucocorticoid regulation.

Biol Reprod 2011 Apr 15;84(4):783-9. Epub 2010 Dec 15.

Department of Physiology, University of Toronto, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1095/biolreprod.110.088468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574638PMC
April 2011

Corticosteroid regulation of P-glycoprotein in the developing blood-brain barrier.

Endocrinology 2011 Mar 14;152(3):1067-79. Epub 2011 Jan 14.

Department of Physiology, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario, Canada M5S 1A8.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2010-1227DOI Listing
March 2011

Testosterone is involved in mediating the effects of prenatal stress in male guinea pig offspring.

J Physiol 2011 Feb 20;589(Pt 3):755-66. Epub 2010 Dec 20.

Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1113/jphysiol.2010.200543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052442PMC
February 2011

Multiple courses of antenatal corticosteroids for preterm birth study: 2-year outcomes.

Pediatrics 2010 Nov 18;126(5):e1045-55. Epub 2010 Oct 18.

Department of Newborn and Developmental Paediatrics, Centre for Mother, Infant, and Child Research, Sunnybrook Health Sciences Centre, M4-233 2075 Bayview Ave Toronto, Ontario, M4N 3M5, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1542/peds.2010-0857DOI Listing
November 2010

Developmental expression of multidrug resistance phosphoglycoprotein (P-gp) in the mouse fetal brain and glucocorticoid regulation.

Brain Res 2010 Oct 13;1357:9-18. Epub 2010 Aug 13.

Department of Physiology, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.brainres.2010.08.016DOI Listing
October 2010

Prenatal synthetic glucocorticoid exposure alters hypothalamic-pituitary-adrenal regulation and pregnancy outcomes in mature female guinea pigs.

J Physiol 2010 Mar 11;588(Pt 5):887-99. Epub 2010 Jan 11.

Department of Physiology, Faculty of Medicine, University of Toronto, Medical Sciences Building, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1113/jphysiol.2009.182139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834946PMC
March 2010

Minireview: transgenerational inheritance of the stress response: a new frontier in stress research.

Endocrinology 2010 Jan 3;151(1):7-13. Epub 2009 Nov 3.

Department of Physiology, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2009-0916DOI Listing
January 2010

Effects of maternal dexamethasone treatment in early pregnancy on pituitary-adrenal axis in fetal sheep.

Endocrinology 2009 Dec 21;150(12):5466-77. Epub 2009 Oct 21.

Department of Physiology and Obstetrics and Gynecology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2009-0086DOI Listing
December 2009

Multidrug resistance phosphoglycoprotein (ABCB1) expression in the guinea pig placenta: developmental changes and regulation by betamethasone.

Can J Physiol Pharmacol 2009 Nov;87(11):973-8

Department of Physiology, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.

View Article

Download full-text PDF

Source
http://www.nrcresearchpress.com/doi/10.1139/Y09-087
Publisher Site
http://dx.doi.org/10.1139/y09-087DOI Listing
November 2009

The effects of prenatal stress on learning in adult offspring is dependent on the timing of the stressor.

Behav Brain Res 2009 Jan 22;197(1):144-9. Epub 2008 Aug 22.

Department of Physiology, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario, M5S 1A8 Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbr.2008.08.018DOI Listing
January 2009

Prenatal stress modifies behavior and hypothalamic-pituitary-adrenal function in female guinea pig offspring: effects of timing of prenatal stress and stage of reproductive cycle.

Endocrinology 2008 Dec 28;149(12):6406-15. Epub 2008 Aug 28.

Department of Physiology, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario, Canada M5S 1A8.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2008-0347DOI Listing
December 2008

The effect of long-term insulin treatment with and without antecedent hypoglycemia on neuropeptide and corticosteroid receptor expression in the brains of diabetic rats.

Brain Res Bull 2008 Oct 29;77(4):149-57. Epub 2008 Jul 29.

University of Toronto - Department of Physiology, Medical Sciences Building, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.brainresbull.2008.07.001DOI Listing
October 2008

Adaptation to intermittent stress promotes maintenance of beta-cell compensation: comparison with food restriction.

Am J Physiol Endocrinol Metab 2008 Oct 19;295(4):E947-58. Epub 2008 Aug 19.

Department of Physiology, University of Toronto, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpendo.90378.2008DOI Listing
October 2008

Molecular regulation of the hypothalamic-pituitary-adrenal axis in adult male guinea pigs after prenatal stress at different stages of gestation.

J Physiol 2008 Sep 17;586(17):4317-26. Epub 2008 Jul 17.

Department of Physiology, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario, Canada, M5S 1A8.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1113/jphysiol.2008.153684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652172PMC
September 2008

Chronic maternal stress affects growth, behaviour and hypothalamo-pituitary-adrenal function in juvenile offspring.

Horm Behav 2008 Sep 20;54(4):514-20. Epub 2008 Mar 20.

CIHR program in Maternal Adversity Vulnerability and Neurodevelopment (MAVAN), University of Toronto, 1 King's College Circle, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yhbeh.2008.02.025DOI Listing
September 2008

Adaptation to mild, intermittent stress delays development of hyperglycemia in the Zucker diabetic Fatty rat independent of food intake: role of habituation of the hypothalamic-pituitary-adrenal axis.

Endocrinology 2008 Jun 6;149(6):2990-3001. Epub 2008 Mar 6.

Departments of Physiology, Medical Sciences Building, University of Toronto, Toronto, Ontario, Canada M5S 1A8.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2007-1473DOI Listing
June 2008

Transgenerational effects of prenatal nutrient restriction on cardiovascular and hypothalamic-pituitary-adrenal function.

J Physiol 2008 Apr 21;586(8):2217-29. Epub 2008 Feb 21.

1Centre for Developmental Origins of Health and Disease, Princess Anne Hospital, Coxford Road, Southampton SO16 5YA, UK.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1113/jphysiol.2007.147967
Publisher Site
http://dx.doi.org/10.1113/jphysiol.2007.147967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2465204PMC
April 2008

Fetal programming of hypothalamic-pituitary-adrenal (HPA) axis function and behavior by synthetic glucocorticoids.

Brain Res Rev 2008 Mar 27;57(2):586-95. Epub 2007 Jul 27.

Department of Physiology, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario, Canada M5S 1A8.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.brainresrev.2007.06.013DOI Listing
March 2008

Fetal mechanisms in neurodevelopmental disorders.

Pediatr Neurol 2008 Mar;38(3):163-76

Department of Neurology and Developmental Medicine, Kennedy Krieger Institute, 707 North Broadway, Baltimore, MD 21205, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pediatrneurol.2007.10.009DOI Listing
March 2008

Swim training prevents hyperglycemia in ZDF rats: mechanisms involved in the partial maintenance of beta-cell function.

Am J Physiol Endocrinol Metab 2008 Feb 20;294(2):E271-83. Epub 2007 Nov 20.

Department of Physiology, University of Toronto, 1 King's College Circle, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpendo.00476.2007DOI Listing
February 2008

Overexposure to antenatal corticosteroids: a global concern.

J Obstet Gynaecol Can 2007 Nov;29(11):879

Departments of Physiology, Obstetrics and Gynaecology, and Medicine, University of Toronto, Toronto ON.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1701-2163(16)32655-XDOI Listing
November 2007

Effects of repeated prenatal glucocorticoid exposure on long-term potentiation in the juvenile guinea-pig hippocampus.

J Physiol 2007 Jun 5;581(Pt 3):1033-42. Epub 2007 Apr 5.

Department of Physiology, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1113/jphysiol.2006.127381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2170854PMC
June 2007

Psychological stressors as a model of maternal adversity: diurnal modulation of corticosterone responses and changes in maternal behavior.

Horm Behav 2007 Jan 10;51(1):77-88. Epub 2006 Oct 10.

CIHR program in Maternal Adversity, Vulnerability and Neurodevelopment (MAVAN) Douglas Hospital Research Center, Department of Psychiatry, McGill University, Montreal, Quebec, Canada H4H 1R3.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yhbeh.2006.08.008DOI Listing
January 2007

Repeated maternal glucocorticoid treatment affects activity and hippocampal NMDA receptor expression in juvenile guinea pigs.

J Physiol 2007 Jan 26;578(Pt 1):249-57. Epub 2006 Oct 26.

Department of Physiology, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario, Canada M5S 1A8.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1113/jphysiol.2006.122887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075130PMC
January 2007

Foetal experience: lifelong consequences.

J Neuroendocrinol 2007 Jan;19(1):73-4

Department of Physiology, Faculty of Medicine, University of Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2826.2006.01504.xDOI Listing
January 2007

Fetal programming of hypothalamo-pituitary-adrenal function: prenatal stress and glucocorticoids.

J Physiol 2006 Apr 9;572(Pt 1):31-44. Epub 2006 Feb 9.

Department of Physiology, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1113/jphysiol.2006.105254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779638PMC
April 2006

Changes in basal hypothalamo-pituitary-adrenal activity during exercise training are centrally mediated.

Am J Physiol Regul Integr Comp Physiol 2005 Nov;289(5):R1360-71

School of Kinesiology and Health Science, York University, 4700 Keele St., Toronto, Ontario, Canada M3J 1P3.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpregu.00103.2005DOI Listing
November 2005

Short periods of prenatal stress affect growth, behaviour and hypothalamo-pituitary-adrenal axis activity in male guinea pig offspring.

J Physiol 2005 Aug 2;566(Pt 3):967-77. Epub 2005 Jun 2.

Department of Physiology, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario, M5S 1A8. Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1113/jphysiol.2005.090191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1464791PMC
August 2005

Hyperglycemia does not increase basal hypothalamo-pituitary-adrenal activity in diabetes but it does impair the HPA response to insulin-induced hypoglycemia.

Am J Physiol Regul Integr Comp Physiol 2005 Jul 17;289(1):R235-46. Epub 2005 Mar 17.

Department of Physiology, 1 King's College Circle, Medical Sciences Bldg. Rm. 3358, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpregu.00674.2004DOI Listing
July 2005

Maternal nutrient deprivation induces sex-specific changes in thyroid hormone receptor and deiodinase expression in the fetal guinea pig brain.

J Physiol 2005 Jul 5;566(Pt 2):467-80. Epub 2005 May 5.

Division of Reproductive and Child Health, University of Birmingham, Birmingham Women's Hospital, Edgbaston, Birmingham B15 2TG, UK.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1113/jphysiol.2005.084673
Publisher Site
http://dx.doi.org/10.1113/jphysiol.2005.084673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1464754PMC
July 2005

Maternal adversity, glucocorticoids and programming of neuroendocrine function and behaviour.

Neurosci Biobehav Rev 2005 Apr;29(2):209-26

Department of Physiology, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ont., Canada M5S 1A8.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neubiorev.2004.10.004DOI Listing
April 2005