Publications by authors named "Stephen Friend"

76Publications

Unlocking stress and forecasting its consequences with digital technology.

NPJ Digit Med 2019 31;2:75. Epub 2019 Jul 31.

4YouandMe, Seattle, WA USA.

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July 2019

Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.

Nat Commun 2016 10 10;7:13205. Epub 2016 Oct 10.

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October 2016

Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.

Nat Commun 2016 08 23;7:12460. Epub 2016 Aug 23.

Sage Bionetworks, Seattle, Washington 98115, USA.

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August 2016

Challenges in identifying cancer genes by analysis of exome sequencing data.

Nat Commun 2016 07 15;7:12096. Epub 2016 Jul 15.

Cancer Cell Map Initiative (CCMI), 9500 Gilman Drive, La Jolla, California 92093, USA.

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July 2016

CANCER. The cancer predisposition revolution.

Science 2016 May;352(6289):1052-3

Sage Bionetworks, Seattle, WA 98109, USA.

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May 2016

The Use of Smartphones for Health Research.

Acad Med 2017 02;92(2):157-160

E.R. Dorsey is professor, Department of Neurology, and director, Center for Human Experimental Technologies (CHET), University of Rochester Medical Center, Rochester, New York. Y.F. Chan is assistant professor, Department of Genetics and Genomic Sciences and Department of Emergency Medicine, and director of digital health, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York. M.V. McConnell is professor, Department of Medicine, and director of cardiovascular health innovation, Stanford University School of Medicine, Stanford, California. S.Y. Shaw is assistant professor, Department of Medicine, and cofounder and codirector, Center for Assessment Technology and Continuous Health (CATCH), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. A.D. Trister is senior physician, Sage Bionetworks, Seattle, Washington. S.H. Friend is president, cofounder, and director, Sage Bionetworks, Seattle, Washington.

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February 2017

Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.

Authors:
Genevera I Allen Nicola Amoroso Catalina Anghel Venkat Balagurusamy Christopher J Bare Derek Beaton Roberto Bellotti David A Bennett Kevin L Boehme Paul C Boutros Laura Caberlotto Cristian Caloian Frederick Campbell Elias Chaibub Neto Yu-Chuan Chang Beibei Chen Chien-Yu Chen Ting-Ying Chien Tim Clark Sudeshna Das Christos Davatzikos Jieyao Deng Donna Dillenberger Richard J B Dobson Qilin Dong Jimit Doshi Denise Duma Rosangela Errico Guray Erus Evan Everett David W Fardo Stephen H Friend Holger Fröhlich Jessica Gan Peter St George-Hyslop Satrajit S Ghosh Enrico Glaab Robert C Green Yuanfang Guan Ming-Yi Hong Chao Huang Jinseub Hwang Joseph Ibrahim Paolo Inglese Anandhi Iyappan Qijia Jiang Yuriko Katsumata John S K Kauwe Arno Klein Dehan Kong Roland Krause Emilie Lalonde Mario Lauria Eunjee Lee Xihui Lin Zhandong Liu Julie Livingstone Benjamin A Logsdon Simon Lovestone Tsung-Wei Ma Ashutosh Malhotra Lara M Mangravite Taylor J Maxwell Emily Merrill John Nagorski Aishwarya Namasivayam Manjari Narayan Mufassra Naz Stephen J Newhouse Thea C Norman Ramil N Nurtdinov Yen-Jen Oyang Yudi Pawitan Shengwen Peng Mette A Peters Stephen R Piccolo Paurush Praveen Corrado Priami Veronica Y Sabelnykova Philipp Senger Xia Shen Andrew Simmons Aristeidis Sotiras Gustavo Stolovitzky Sabina Tangaro Andrea Tateo Yi-An Tung Nicholas J Tustison Erdem Varol George Vradenburg Michael W Weiner Guanghua Xiao Lei Xie Yang Xie Jia Xu Hojin Yang Xiaowei Zhan Yunyun Zhou Fan Zhu Hongtu Zhu Shanfeng Zhu

Alzheimers Dement 2016 06 11;12(6):645-53. Epub 2016 Apr 11.

School of Computer Science, Fudan University, Shanghai, Shanghai, China; Shanghai Key Lab of Intelligent Information Processing, Fudan University, Shanghai, Shanghai, China; Centre for Computational Systems Biology, Fudan University, Shanghai, China.

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June 2016

First, design for data sharing.

Nat Biotechnol 2016 Apr;34(4):377-9

Sage Bionetworks, Seattle, Washington, USA.

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April 2016

Smartphones as new tools in the management and understanding of Parkinson's disease.

NPJ Parkinsons Dis 2016 3;2:16006. Epub 2016 Mar 3.

Sage Bionetworks, Seattle, WA, USA.

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March 2016

App-enabled trial participation: Tectonic shift or tepid rumble?

Authors:
Stephen H Friend

Sci Transl Med 2015 Jul;7(297):297ed10

Stephen H. Friend is the president of Sage Bionetworks, Seattle, WA 98109, USA. E-mail:

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July 2015

Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection.

Nat Methods 2015 Jul 18;12(7):623-30. Epub 2015 May 18.

1] Informatics and Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada. [2] Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. [3] Department of Pharmacology &Toxicology, University of Toronto, Toronto, Ontario, Canada.

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July 2015

The Prostate Cancer DREAM Challenge: A Community-Wide Effort to Use Open Clinical Trial Data for the Quantitative Prediction of Outcomes in Metastatic Prostate Cancer.

Oncologist 2015 May 16;20(5):459-60. Epub 2015 Mar 16.

Project Data Sphere, Raleigh, North Carolina, USA; Sanofi US, Bridgewater, New Jersey, USA; Sage Bionetworks, Seattle, Washington, USA; IBM T.J. Watson Research Center, Yorktown Heights, New York, USA; Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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May 2015

Database of genomic biomarkers for cancer drugs and clinical targetability in solid tumors.

Cancer Discov 2015 Feb;5(2):118-23

Sage Bionetworks, Fred Hutchinson Cancer Research Center, Seattle, Washington.

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February 2015

Social interactomes for enabling research communities.

Cancer Discov 2014 Nov;4(11):1265-8

Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland. Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California. Department of Cell and Molecular Pharmacology, University of California, San Francisco, California.

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November 2014

Translational genomics. Clues from the resilient.

Science 2014 May;344(6187):970-2

Icahn School of Medicine at Mount Sinai, Department of Genetics and Genomic Sciences and the Icahn Institute for Genomics and Multiscale Biology, New York, NY 10029, USA.

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May 2014

Cancer. Potential of the synthetic lethality principle.

Science 2013 Nov;342(6160):809-11

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.

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November 2013

Metcalfe's law and the biology information commons.

Nat Biotechnol 2013 Apr;31(4):297-303

Sage Bionetworks, Seattle, Washington, USA.

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April 2013

Genome-wide methylation profiles reveal quantitative views of human aging rates.

Mol Cell 2013 Jan 21;49(2):359-367. Epub 2012 Nov 21.

Molecular Medicine Research Center and Department of Ophthalmology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China.

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January 2013

Q&A: Stephen Friend on a bioinformation commons.

Authors:
Stephen Friend

Cancer Discov 2012 Aug 19;2(8):658. Epub 2012 Jul 19.

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August 2012

Leveraging models of cell regulation and GWAS data in integrative network-based association studies.

Nat Genet 2012 Jul 27;44(8):841-7. Epub 2012 Jul 27.

Columbia Initiative in Systems Biology, Columbia University, New York, New York, USA.

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July 2012

The precompetitive space: time to move the yardsticks.

Sci Transl Med 2011 Mar;3(76):76cm10

Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.

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March 2011

Point: Are we prepared for the future doctor visit?

Nat Biotechnol 2011 Mar;29(3):215-8

Sage Bionetworks, Seattle, Washington, USA.

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March 2011

Predictive, personalized, preventive, participatory (P4) cancer medicine.

Nat Rev Clin Oncol 2011 03;8(3):184-7

Institute for Systems Biology, 1441 North 34th Street, Seattle, WA 98103, USA.

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March 2011

An accelerated pathway for targeted cancer therapies.

Nat Rev Drug Discov 2011 02;10(2):79-80

Engelberg Center for Health Care Reform, Brookings Institution, Washington DC, USA.

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February 2011

Something in common.

Authors:
Stephen H Friend

Sci Transl Med 2010 Jul;2(40):40ed6

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July 2010

A network view of disease and compound screening.

Nat Rev Drug Discov 2009 04;8(4):286-95

Eric E. Schadt is at Rosetta Inpharmatics, LLC, Merck & Co., Inc., 401 Terry Avenue North, Seattle, Washington 98109, USA.

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April 2009

Accelerating drug discovery: Open source cancer cell biology?

Cancer Cell 2006 Nov;10(5):349-51

Merck Research Laboratories, Merck & Co, Inc., Upper Gwynedd, Pennsylvania 19454, USA.

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November 2006

Cancer biomarkers--an invitation to the table.

Science 2006 May;312(5777):1165-8

H. Lee Moffitt Cancer Center, University of South Florida, Tampa, FL 33613, USA.

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May 2006

Gene expression changes associated with progression and response in chronic myeloid leukemia.

Proc Natl Acad Sci U S A 2006 Feb 13;103(8):2794-9. Epub 2006 Feb 13.

Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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February 2006

Embracing complexity, inching closer to reality.

Sci STKE 2005 Aug 2;2005(295):pe40. Epub 2005 Aug 2.

Rosetta Inpharmatics, 401 Terry Avenue North, Seattle, WA 98109, USA.

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August 2005

How molecular profiling could revolutionize drug discovery.

Nat Rev Drug Discov 2005 Apr;4(4):345-50

GHC Technologies, Inc., 505 Coast Boulevard South, Suite 309, La Jolla, California 92037, USA.

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April 2005

Alfred Knudson: the importance of a visionary who enables scientists.

Authors:
Stephen H Friend

Genes Chromosomes Cancer 2003 Dec;38(4):326-8

Merck Research Laboratories, Merck & Company, West Point, Pennsylvania, USA.

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December 2003

Toxicogenomics and drug discovery: will new technologies help us produce better drugs?

Nat Rev Drug Discov 2002 01;1(1):84-8

Rosetta Inpharmatics, 12040 115th Avenue NE, Kirkland, Washington 98034, USA.

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January 2002

Thirteenth annual pezcoller symposium: focusing analytical tools on complexity in cancer.

Cancer Res 2002 Jul;62(13):3883-7

Pharmacology and Therapeutics Department, Roswell Park Cancer Institute, Buffalo, New York 14263, USA.

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July 2002

The magic of microarrays.

Sci Am 2002 Feb;286(2):44-9, 53

Rosetta Inpharmatics, Kirkland, Wash., USA.

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February 2002