Stephen F Madden

Stephen F Madden

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Stephen F Madden

Stephen F Madden

Publications by authors named "Stephen F Madden"

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Elevated Plasma microRNA-206 Levels Predict Cognitive Decline and Progression to Dementia from Mild Cognitive Impairment.

Biomolecules 2019 Nov 13;9(11). Epub 2019 Nov 13.

Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland.

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http://dx.doi.org/10.3390/biom9110734DOI Listing
November 2019

Altered Steroid Milieu in AI-Resistant Breast Cancer Facilitates AR Mediated Gene-Expression Associated with Poor Response to Therapy.

Mol Cancer Ther 2019 Oct 9;18(10):1731-1743. Epub 2019 Jul 9.

Endocrine Oncology Research Group, Department of Surgery, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland.

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http://dx.doi.org/10.1158/1535-7163.MCT-18-0791DOI Listing
October 2019

The Mutant p53-Targeting Compound APR-246 Induces ROS-Modulating Genes in Breast Cancer Cells.

Transl Oncol 2018 Dec 6;11(6):1343-1349. Epub 2018 Sep 6.

UCD School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland; UCD Clinical Research Centre, St. Vincent's University Hospital, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.tranon.2018.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132178PMC
December 2018

Complex spectrum of phenobarbital effects in a mouse model of neonatal hypoxia-induced seizures.

Sci Rep 2018 07 3;8(1):9986. Epub 2018 Jul 3.

Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, 123, St Stephen Green, Dublin, 2, Dublin, Ireland.

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http://dx.doi.org/10.1038/s41598-018-28044-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030182PMC
July 2018

Development of a personalized therapeutic strategy for ERBB-gene-mutated cancers.

Ther Adv Med Oncol 2018 9;10:1758834017746040. Epub 2018 Jan 9.

Medical Oncology Group, Department of Molecular Medicine, Royal College of Surgeons in Ireland, ERC Smurfit Building, Dublin, 9, Ireland.

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http://dx.doi.org/10.1177/1758834017746040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784557PMC
January 2018

Tyrosine kinase inhibitors as modulators of trastuzumab-mediated antibody-dependent cell-mediated cytotoxicity in breast cancer cell lines.

Cell Immunol 2017 Sep 15;319:35-42. Epub 2017 Jul 15.

National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland; Department of Medical Oncology, St Vincent's University Hospital, Elm Park, Dublin 4, Ireland.

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https://linkinghub.elsevier.com/retrieve/pii/S00088749173011
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http://dx.doi.org/10.1016/j.cellimm.2017.07.005DOI Listing
September 2017

Dual inhibition of IGF1R and ER enhances response to trastuzumab in HER2 positive breast cancer cells.

Int J Oncol 2017 Jun 26;50(6):2221-2228. Epub 2017 Apr 26.

National Institute for Cellular Biotechnology, Dublin City University, Dublin 9, Ireland.

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http://dx.doi.org/10.3892/ijo.2017.3976DOI Listing
June 2017

Vitamin D receptor as a target for breast cancer therapy.

Endocr Relat Cancer 2017 04 17;24(4):181-195. Epub 2017 Feb 17.

UCD School of MedicineConway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1530/ERC-16-0463DOI Listing
April 2017

Bidirectional KCNQ1:β-catenin interaction drives colorectal cancer cell differentiation.

Proc Natl Acad Sci U S A 2017 04 3;114(16):4159-4164. Epub 2017 Apr 3.

Department of Molecular Medicine, Royal College of Surgeons in Ireland (RCSI) Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland;

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http://dx.doi.org/10.1073/pnas.1702913114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402468PMC
April 2017

Preclinical evaluation of the AR inhibitor enzalutamide in triple-negative breast cancer cells.

Endocr Relat Cancer 2016 Apr 1;23(4):323-34. Epub 2016 Mar 1.

School of MedicineUniversity College Dublin, Ireland UCD Clinical Research CentreSt. Vincent's University Hospital, Dublin, Ireland.

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https://erc.bioscientifica.com/view/journals/erc/23/4/323.xm
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http://dx.doi.org/10.1530/ERC-16-0068DOI Listing
April 2016

ADAM10: a new player in breast cancer progression?

Br J Cancer 2015 Sep 18;113(6):945-51. Epub 2015 Aug 18.

UCD School of Medicine and Medical Science, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1038/bjc.2015.288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578086PMC
September 2015

Circulating miRNAs miR-34a and miR-150 associated with colorectal cancer progression.

BMC Cancer 2015 Apr 30;15:329. Epub 2015 Apr 30.

Molecular Therapeutics for Cancer Ireland, National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.

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http://dx.doi.org/10.1186/s12885-015-1327-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417244PMC
April 2015

OvMark: a user-friendly system for the identification of prognostic biomarkers in publically available ovarian cancer gene expression datasets.

Mol Cancer 2014 Oct 24;13:241. Epub 2014 Oct 24.

Molecular Therapeutics for Cancer Ireland, National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.

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http://dx.doi.org/10.1186/1476-4598-13-241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219121PMC
October 2014

A gene expression profile indicative of early stage HER2 targeted therapy response.

Mol Cancer 2013 Jul 1;12:69. Epub 2013 Jul 1.

Molecular Therapeutics for Cancer Ireland, National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.

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http://dx.doi.org/10.1186/1476-4598-12-69DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725168PMC
July 2013

Identification of transcription factors associated with castration-resistance: is the serum responsive factor a potential therapeutic target?

Prostate 2013 May 28;73(7):743-53. Epub 2013 Jan 28.

UCD School of Medicine and Medical Science, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland.

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http://dx.doi.org/10.1002/pros.22618DOI Listing
May 2013

Gene expression analysis in prostate cancer: the importance of the endogenous control.

Prostate 2013 Mar 27;73(4):382-90. Epub 2012 Aug 27.

Prostate Molecular Oncology, Academic Unit of Clinical and Molecular Oncology, Institute of Molecular Medicine, Trinity College Dublin, Ireland.

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http://dx.doi.org/10.1002/pros.22578DOI Listing
March 2013

CGCDB: a web-based resource for the investigation of gene coexpression in CHO cell culture.

Biotechnol Bioeng 2012 Jun 4;109(6):1368-70. Epub 2012 Jan 4.

National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.

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http://dx.doi.org/10.1002/bit.24416DOI Listing
June 2012

Gene expression changes as markers of early lapatinib response in a panel of breast cancer cell lines.

Mol Cancer 2012 Jun 18;11:41. Epub 2012 Jun 18.

Molecular Therapeutics for Cancer Ireland, National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.

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http://dx.doi.org/10.1186/1476-4598-11-41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439312PMC
June 2012

Proteomic portrait of human breast cancer progression identifies novel prognostic markers.

Cancer Res 2012 May 13;72(9):2428-39. Epub 2012 Mar 13.

Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3711DOI Listing
May 2012

Characterization and response of newly developed high-grade glioma cultures to the tyrosine kinase inhibitors, erlotinib, gefitinib and imatinib.

Exp Cell Res 2012 Mar 20;318(5):641-52. Epub 2012 Jan 20.

National Institute for Cellular Biotechnology, Dublin City University, Dublin 9, Ireland.

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http://dx.doi.org/10.1016/j.yexcr.2012.01.014DOI Listing
March 2012

Sustained expression of steroid receptor coactivator SRC-2/TIF-2 is associated with better prognosis in malignant pleural mesothelioma.

J Thorac Oncol 2012 Jan;7(1):243-8

Department of Molecular Medicine, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland.

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http://linkinghub.elsevier.com/retrieve/pii/S155608641531784
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http://dx.doi.org/10.1097/JTO.0b013e31822f6544DOI Listing
January 2012

5-AZA-2'-deoxycytidine induced demethylation influences N-glycosylation of secreted glycoproteins in ovarian cancer.

Epigenetics 2011 Nov 1;6(11):1362-72. Epub 2011 Nov 1.

Dublin-Oxford NIBRT Glycobiology Laboratory, NIBRT, Conway Institute, University College Dublin, Belfield, Dublin, Ireland.

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http://dx.doi.org/10.4161/epi.6.11.17977DOI Listing
November 2011

Detecting microRNA activity from gene expression data.

BMC Bioinformatics 2010 May 18;11:257. Epub 2010 May 18.

School of Medicine and Medical Science, Conway Institute, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1186/1471-2105-11-257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885376PMC
May 2010

Hypoxia selectively activates the CREB family of transcription factors in the in vivo lung.

Am J Respir Crit Care Med 2008 Nov 8;178(9):977-83. Epub 2008 Aug 8.

University College Dublin, School of Medicine and Medical Science, and Conway Institute of Biomolecular and Biomedical Research, Dublin, Ireland.

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http://www.atsjournals.org/doi/abs/10.1164/rccm.200712-1890O
Publisher Site
http://dx.doi.org/10.1164/rccm.200712-1890OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643223PMC
November 2008

Distinct patterns in the regulation and evolution of human cancer genes.

In Silico Biol 2008 ;8(1):33-46

Research Unit on Biomedical Informatics, Experimental and Health Science Department, Universitat Pompeu Fabra, Barcelona, 08080, Spain.

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http://public-files.prbb.org/publicacions/6101dfd0-f5e0-012b
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July 2008

Integrating transcription factor binding site information with gene expression datasets.

Bioinformatics 2007 Feb 24;23(3):298-305. Epub 2006 Nov 24.

UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1093/bioinformatics/btl597DOI Listing
February 2007

ETV4 and Myeov knockdown impairs colon cancer cell line proliferation and invasion.

Biochem Biophys Res Commun 2006 Jun 27;345(1):216-21. Epub 2006 Apr 27.

Conway Institute of Biomolecular and Biomedical Research, UCD, Ireland.

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http://dx.doi.org/10.1016/j.bbrc.2006.04.094DOI Listing
June 2006

Digital extractor: analysis of digital differential display output.

Bioinformatics 2003 Aug;19(12):1594-5

Human Genomics and Bioinformatics Research Unit, Department of Medicine and Therapeutics, University College Dublin, Mater Misericordiae Hospital, The Dublin Molecular Medicine Centre, 41 Eccles St, Dublin 7, Ireland.

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http://dx.doi.org/10.1093/bioinformatics/btg198DOI Listing
August 2003