Publications by authors named "Stephen Burgess"

100Publications

Rising numbers of positive covid-19 tests in the UK.

BMJ 2020 09 17;370:m3605. Epub 2020 Sep 17.

Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.

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http://dx.doi.org/10.1136/bmj.m3605DOI Listing
September 2020

Association of Prior Atherosclerotic Cardiovascular Disease with Dementia After Stroke: A Retrospective Cohort Study.

J Alzheimers Dis 2020 Aug 17. Epub 2020 Aug 17.

Primary Care Unit, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.3233/JAD-200536DOI Listing
August 2020

MR-Clust: Clustering of genetic variants in Mendelian randomization with similar causal estimates.

Bioinformatics 2020 Sep 11. Epub 2020 Sep 11.

MRC Biostatistics Unit, University of Cambridge, Cambridge, CB2 0SR, UK.

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http://dx.doi.org/10.1093/bioinformatics/btaa778DOI Listing
September 2020

Sleep duration and risk of overall and 22 site-specific cancers: A Mendelian randomization study.

Int J Cancer 2020 Sep 7. Epub 2020 Sep 7.

Unit of Medical Epidemiology, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1002/ijc.33286DOI Listing
September 2020

Are we underestimating seroprevalence of SARS-CoV-2?

BMJ 2020 09 3;370:m3364. Epub 2020 Sep 3.

Clinical Pharmacology and Therapeutics Section, Institute of Medical and Biomedical Education and Institute for Infection and Immunity, St George's, University of London, London, UK.

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http://dx.doi.org/10.1136/bmj.m3364DOI Listing
September 2020

A method for fast field settling in cryogen-free superconducting magnets for NMR.

Solid State Nucl Magn Reson 2020 Aug 19;109:101684. Epub 2020 Aug 19.

Cryogenic Ltd, London, UK.

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http://dx.doi.org/10.1016/j.ssnmr.2020.101684DOI Listing
August 2020

Genetically raised serum bilirubin levels and lung cancer: a cohort study and Mendelian randomisation using UK Biobank.

Thorax 2020 Aug 27. Epub 2020 Aug 27.

Department of Primary Care & Population Health, UCL, London, UK.

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http://dx.doi.org/10.1136/thoraxjnl-2020-214756DOI Listing
August 2020

Effects of tumour necrosis factor on cardiovascular disease and cancer: A two-sample Mendelian randomization study.

EBioMedicine 2020 Aug 14;59:102956. Epub 2020 Aug 14.

Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm 17177, Sweden; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2020.102956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452586PMC
August 2020

Polygenic modelling of treatment effect heterogeneity.

Genet Epidemiol 2020 Aug 10. Epub 2020 Aug 10.

MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1002/gepi.22347DOI Listing
August 2020

Insulin-like growth factor-1 and site-specific cancers: A Mendelian randomization study.

Cancer Med 2020 Jul 27. Epub 2020 Jul 27.

Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1002/cam4.3345DOI Listing
July 2020

Impact of Genetically Predicted Red Blood Cell Traits on Venous Thromboembolism: Multivariable Mendelian Randomization Study Using UK Biobank.

J Am Heart Assoc 2020 Jul 8;9(14):e016771. Epub 2020 Jul 8.

School of Public Health Li Ka Shing Faculty of Medicine The University of Hong Kong Hong Kong SAR, China.

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http://dx.doi.org/10.1161/JAHA.120.016771DOI Listing
July 2020

Genetically Predicted Midlife Blood Pressure and Coronary Artery Disease Risk: Mendelian Randomization Analysis.

J Am Heart Assoc 2020 Jul 4;9(14):e016773. Epub 2020 Jul 4.

Institute for Stroke and Dementia Research University Hospital of Ludwig-Maximilians-University Munich Germany.

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http://dx.doi.org/10.1161/JAHA.120.016773DOI Listing
July 2020

IGF-1 and cardiometabolic diseases: a Mendelian randomisation study.

Diabetologia 2020 Sep 16;63(9):1775-1782. Epub 2020 Jun 16.

Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1007/s00125-020-05190-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406523PMC
September 2020

Lipoprotein(a) in Alzheimer, Atherosclerotic, Cerebrovascular, Thrombotic, and Valvular Disease: Mendelian Randomization Investigation.

Circulation 2020 Jun 1;141(22):1826-1828. Epub 2020 Jun 1.

British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, United Kingdom (A.M.M., T.J., A.S.B., S.B.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.120.045826DOI Listing
June 2020

Alcohol Consumption and Cardiovascular Disease: A Mendelian Randomization Study.

Circ Genom Precis Med 2020 Jun 5;13(3):e002814. Epub 2020 May 5.

Department of Surgical Sciences, Uppsala University, Uppsala, Sweden (S.C.L., K.M.).

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http://dx.doi.org/10.1161/CIRCGEN.119.002814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299220PMC
June 2020

Is Type 2 Diabetes Causally Associated With Cancer Risk? Evidence From a Two-Sample Mendelian Randomization Study.

Diabetes 2020 Jul 29;69(7):1588-1596. Epub 2020 Apr 29.

Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

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http://dx.doi.org/10.2337/db20-0084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306131PMC
July 2020

Genetic predisposition to smoking in relation to 14 cardiovascular diseases.

Eur Heart J 2020 Apr 16. Epub 2020 Apr 16.

Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.

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http://dx.doi.org/10.1093/eurheartj/ehaa193DOI Listing
April 2020

A comparison of robust Mendelian randomization methods using summary data.

Genet Epidemiol 2020 Jun 6;44(4):313-329. Epub 2020 Apr 6.

Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1002/gepi.22295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317850PMC
June 2020

Circulating interleukins in relation to coronary artery disease, atrial fibrillation and ischemic stroke and its subtypes: A two-sample Mendelian randomization study.

Int J Cardiol 2020 Aug 21;313:99-104. Epub 2020 Mar 21.

Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2020.03.053DOI Listing
August 2020

Causal associations of thyroid function and dysfunction with overall, breast and thyroid cancer: A two-sample Mendelian randomization study.

Int J Cancer 2020 Oct 3;147(7):1895-1903. Epub 2020 Apr 3.

Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1002/ijc.32988DOI Listing
October 2020

Iron Status and Cancer Risk in UK Biobank: A Two-Sample Mendelian Randomization Study.

Nutrients 2020 Feb 19;12(2). Epub 2020 Feb 19.

Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.3390/nu12020526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071358PMC
February 2020

Urinary Albumin, Sodium, and Potassium and Cardiovascular Outcomes in the UK Biobank: Observational and Mendelian Randomization Analyses.

Hypertension 2020 Mar 3;75(3):714-722. Epub 2020 Feb 3.

From the Division of Cardiovascular Medicine, Department of Medicine (D.Z., T.L.A., E.I.), Stanford University School of Medicine, CA.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.14028DOI Listing
March 2020

A robust and efficient method for Mendelian randomization with hundreds of genetic variants.

Nat Commun 2020 01 17;11(1):376. Epub 2020 Jan 17.

BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/s41467-019-14156-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969055PMC
January 2020

Selecting likely causal risk factors from high-throughput experiments using multivariable Mendelian randomization.

Nat Commun 2020 01 7;11(1):29. Epub 2020 Jan 7.

MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/s41467-019-13870-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946691PMC
January 2020

Plasma Phospholipid Fatty Acids, and Risk of 15 Cardiovascular Diseases: A Mendelian Randomisation Study.

Nutrients 2019 Dec 7;11(12). Epub 2019 Dec 7.

Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.3390/nu11123001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950527PMC
December 2019

On the magnetic field stability of cryogen-free magnets for magnetic resonance applications.

Solid State Nucl Magn Reson 2020 Feb 30;105:101639. Epub 2019 Nov 30.

Cryogenic Ltd, London, UK.

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http://dx.doi.org/10.1016/j.ssnmr.2019.101639DOI Listing
February 2020

Genetic Determinants of Lipids and Cardiovascular Disease Outcomes: A Wide-Angled Mendelian Randomization Investigation.

Circ Genom Precis Med 2019 12 22;12(12):e002711. Epub 2019 Nov 22.

Department of Public Health and Primary Care, BHF Cardiovascular Epidemiology Unit (E.A., P.C., J.M.B.R., A.M.M., S. Bell, A.S.B., E.D.A., J.P., S. Burgess), University of Cambridge, United Kingdom.

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http://dx.doi.org/10.1161/CIRCGEN.119.002711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6922071PMC
December 2019

Lipid lowering and Alzheimer disease risk: A mendelian randomization study.

Ann Neurol 2020 01;87(1):30-39

Institute of Cardiovascular Science, Faculty of Population Health, University College London, London, United Kingdom.

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http://dx.doi.org/10.1002/ana.25642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944510PMC
January 2020

Robust methods in Mendelian randomization via penalization of heterogeneous causal estimates.

PLoS One 2019 23;14(9):e0222362. Epub 2019 Sep 23.

Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0222362PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756542PMC
March 2020

Factorial Mendelian randomization: using genetic variants to assess interactions.

Int J Epidemiol 2019 Aug 1. Epub 2019 Aug 1.

Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1093/ije/dyz161DOI Listing
August 2019

How humans can contribute to Mendelian randomization analyses.

Int J Epidemiol 2019 06;48(3):661-664

MRC Integrative Epidemiology Unit, School of Social and Community Medicine, Bristol, UK.

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http://dx.doi.org/10.1093/ije/dyz152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739231PMC
June 2019

Smoking and stroke: A mendelian randomization study.

Ann Neurol 2019 09 3;86(3):468-471. Epub 2019 Jul 3.

Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1002/ana.25534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701987PMC
September 2019

PhenoScanner V2: an expanded tool for searching human genotype-phenotype associations.

Bioinformatics 2019 11;35(22):4851-4853

MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.

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http://dx.doi.org/10.1093/bioinformatics/btz469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6853652PMC
November 2019

Do Cerebral Small Vessel Disease and Multiple Sclerosis Share Common Mechanisms of White Matter Injury?

Stroke 2019 08 21;50(8):1968-1972. Epub 2019 Jun 21.

From the Department of Clinical Neurosciences (R.B.B., M.T., S.S., H.S.M.), University of Cambridge, United Kingdom.

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http://dx.doi.org/10.1161/STROKEAHA.118.023649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661245PMC
August 2019

Circulating phylloquinone, inactive Matrix Gla protein and coronary heart disease risk: A two-sample Mendelian Randomization study.

Clin Nutr 2020 Apr 7;39(4):1131-1136. Epub 2019 May 7.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.clnu.2019.04.024DOI Listing
April 2020

Resting Heart Rate and Cardiovascular Disease.

Circ Genom Precis Med 2019 03;12(3):e002459

Department of Public Health and Primary Care (A.M.M., S.B.), University of Cambridge, United Kingdom.

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http://dx.doi.org/10.1161/CIRCGEN.119.002459DOI Listing
March 2019

Mendelian Randomization Study of and Cardiovascular Disease.

N Engl J Med 2019 03;380(11):1033-1042

From the Centre for Naturally Randomized Trials (B.A.F., T.B.F.), Medical Research Council, British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care (B.A.F., S.B., C.O.-W., A.M.W., A.S.B., E.D.A., J.D.), Medical Research Council Biostatistics Unit (S.B.), and NIHR Blood and Transplant Research Unit in Donor Health and Genomics (A.S.B., E.D.A., J.D.), University of Cambridge, Cambridge, and Imperial Centre for Cardiovascular Disease Prevention, Department of Primary Care and Public Health, School of Public Health, Imperial College London, London (K.K.R.) - all in the United Kingdom; the Department of Pharmacologic and Biomolecular Sciences, University of Milan and Multimedica IRCCS, Milan (A.L.C.); Michigan State University, East Lansing (D.R.N.); the Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam (J.J.P.K.); and Monash University, Clayton, VIC, Australia (S.J.N.).

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http://www.nejm.org/doi/10.1056/NEJMoa1806747
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http://dx.doi.org/10.1056/NEJMoa1806747DOI Listing
March 2019

Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study.

Neurology 2019 02 25;92(9):e944-e950. Epub 2019 Jan 25.

From the Unit of Cardiovascular and Nutritional Epidemiology (S.C.L.), Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Stroke Research Group, Department of Clinical Neurosciences (M.T., H.S.M.), MRC Biostatistics Unit (S.B.), and Department of Public Health and Primary Care (S.B.), University of Cambridge, UK; Department of Cerebrovascular Diseases (G.B.B.), Fondazione IRCCS-Istituto Neurologico Carlo Besta, Milano, Italy; Department of Clinical Pathology and Genetics (C.J.), Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg; and Department of Surgical Sciences (K.M.), Uppsala University, Sweden.

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http://dx.doi.org/10.1212/WNL.0000000000007001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404465PMC
February 2019

Body composition and atrial fibrillation: a Mendelian randomization study.

Eur Heart J 2019 04;40(16):1277-1282

Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, 300 Pasteur Dr, Stanford, CA, USA.

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https://academic.oup.com/eurheartj/advance-article/doi/10.10
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http://dx.doi.org/10.1093/eurheartj/ehz003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475522PMC
April 2019

Thyroid Function and Dysfunction in Relation to 16 Cardiovascular Diseases.

Circ Genom Precis Med 2019 03;12(3):e002468

Department of Public Health and Primary Care (E.A., A.M.M., S.B.).

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http://dx.doi.org/10.1161/CIRCGEN.118.002468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443057PMC
March 2019

Cardiovascular Risk Factors Associated With Venous Thromboembolism.

JAMA Cardiol 2019 02;4(2):163-173

London School of Hygiene and Tropical Medicine, London, United Kingdom.

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http://cardiology.jamanetwork.com/article.aspx?doi=10.1001/j
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http://dx.doi.org/10.1001/jamacardio.2018.4537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386140PMC
February 2019

The interaction of lipid-liganded gold clusters (Aurora ) with lipid bilayers.

Chem Phys Lipids 2019 01 28;218:40-46. Epub 2018 Nov 28.

Instituto Biofisika (UPV/EHU, CSIC), Barrio Sarriena s/n, 48940, Leioa, Spain; Departamento de Bioquímica y Biología Molecular, Universidad del País Vasco, Barrio Sarriena s/n, 48940, Leioa, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00093084183023
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http://dx.doi.org/10.1016/j.chemphyslip.2018.11.007DOI Listing
January 2019

Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies.

Authors:
Lisa Pennells Stephen Kaptoge Angela Wood Mike Sweeting Xiaohui Zhao Ian White Stephen Burgess Peter Willeit Thomas Bolton Karel G M Moons Yvonne T van der Schouw Randi Selmer Kay-Tee Khaw Vilmundur Gudnason Gerd Assmann Philippe Amouyel Veikko Salomaa Mika Kivimaki Børge G Nordestgaard Michael J Blaha Lewis H Kuller Hermann Brenner Richard F Gillum Christa Meisinger Ian Ford Matthew W Knuiman Annika Rosengren Debbie A Lawlor Henry Völzke Cyrus Cooper Alejandro Marín Ibañez Edoardo Casiglia Jussi Kauhanen Jackie A Cooper Beatriz Rodriguez Johan Sundström Elizabeth Barrett-Connor Rachel Dankner Paul J Nietert Karina W Davidson Robert B Wallace Dan G Blazer Cecilia Björkelund Chiara Donfrancesco Harlan M Krumholz Aulikki Nissinen Barry R Davis Sean Coady Peter H Whincup Torben Jørgensen Pierre Ducimetiere Maurizio Trevisan Gunnar Engström Carlos J Crespo Tom W Meade Marjolein Visser Daan Kromhout Stefan Kiechl Makoto Daimon Jackie F Price Agustin Gómez de la Cámara J Wouter Jukema Benoît Lamarche Altan Onat Leon A Simons Maryam Kavousi Yoav Ben-Shlomo John Gallacher Jacqueline M Dekker Hisatomi Arima Nawar Shara Robert W Tipping Ronan Roussel Eric J Brunner Wolfgang Koenig Masaru Sakurai Jelena Pavlovic Ron T Gansevoort Dorothea Nagel Uri Goldbourt Elizabeth L M Barr Luigi Palmieri Inger Njølstad Shinichi Sato W M Monique Verschuren Cherian V Varghese Ian Graham Oyere Onuma Philip Greenland Mark Woodward Majid Ezzati Bruce M Psaty Naveed Sattar Rod Jackson Paul M Ridker Nancy R Cook Ralph B D'Agostino Simon G Thompson John Danesh Emanuele Di Angelantonio

Eur Heart J 2019 02;40(7):621-631

Department of Public Health and Primary Care, University of Cambridge, 2 Worts' Causeway, Cambridge, UK.

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http://fdslive.oup.com/www.oup.com/pdf/production_in_progres
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http://dx.doi.org/10.1093/eurheartj/ehy653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374687PMC
February 2019

Contextualizing selection bias in Mendelian randomization: how bad is it likely to be?

Int J Epidemiol 2019 06;48(3):691-701

MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.

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https://academic.oup.com/ije/advance-article/doi/10.1093/ije
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http://dx.doi.org/10.1093/ije/dyy202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659463PMC
June 2019

Mendelian randomization in the bone field.

Bone 2019 09 12;126:51-58. Epub 2018 Oct 12.

MRC Biostatistics Unit, University of Cambridge, United Kingdom; Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S87563282183039
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http://dx.doi.org/10.1016/j.bone.2018.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697532PMC
September 2019

Genetic association between adiposity and gout: a Mendelian randomization study.

Rheumatology (Oxford) 2018 12;57(12):2145-2148

Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

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https://academic.oup.com/rheumatology/advance-article/doi/10
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http://dx.doi.org/10.1093/rheumatology/key229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697177PMC
December 2018

A Bayesian approach to Mendelian randomization with multiple pleiotropic variants.

Biostatistics 2020 01;21(1):86-101

Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1093/biostatistics/kxy027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920542PMC
January 2020

Mendelian randomization with a binary exposure variable: interpretation and presentation of causal estimates.

Eur J Epidemiol 2018 Oct 23;33(10):947-952. Epub 2018 Jul 23.

Department of Epidemiology, Erasmus MC, Rotterdam, Netherlands.

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http://dx.doi.org/10.1007/s10654-018-0424-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153517PMC
October 2018

What indeed can be tested with an instrumental variable?

Authors:
Stephen Burgess

Eur J Epidemiol 2018 Aug;33(8):695-697

MRC Biostatistics Unit, Cambridge Institute of Public Health, University of Cambridge, Robinson Way, Cambridge, CB2 0SR, UK.

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http://dx.doi.org/10.1007/s10654-018-0423-7DOI Listing
August 2018

Genetic predictors of testosterone and their associations with cardiovascular disease and risk factors: A Mendelian randomization investigation.

Int J Cardiol 2018 Sep 18;267:171-176. Epub 2018 May 18.

Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, Cambridgeshire, UK; MRC Biostatistics Unit, University of Cambridge, Cambridge, Cambridgeshire, UK; Homerton College, University of Cambridge, Cambridge, Cambridgeshire, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01675273173610
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http://dx.doi.org/10.1016/j.ijcard.2018.05.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024225PMC
September 2018

Serum magnesium levels and risk of coronary artery disease: Mendelian randomisation study.

BMC Med 2018 05 17;16(1):68. Epub 2018 May 17.

Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1186/s12916-018-1065-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956816PMC
May 2018

Serum 25-hydroxyvitamin D levels and risk of lung cancer and histologic types: a Mendelian randomisation analysis of the HUNT study.

Eur Respir J 2018 06 7;51(6). Epub 2018 Jun 7.

Dept of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

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http://dx.doi.org/10.1183/13993003.00329-2018DOI Listing
June 2018

Inferring Causal Relationships Between Risk Factors and Outcomes from Genome-Wide Association Study Data.

Annu Rev Genomics Hum Genet 2018 08 25;19:303-327. Epub 2018 Apr 25.

MRC Biostatistics Unit, University of Cambridge, Cambridge CB2 0SR, United Kingdom; email:

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http://dx.doi.org/10.1146/annurev-genom-083117-021731DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481551PMC
August 2018

Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies.

Authors:
Angela M Wood Stephen Kaptoge Adam S Butterworth Peter Willeit Samantha Warnakula Thomas Bolton Ellie Paige Dirk S Paul Michael Sweeting Stephen Burgess Steven Bell William Astle David Stevens Albert Koulman Randi M Selmer W M Monique Verschuren Shinichi Sato Inger Njølstad Mark Woodward Veikko Salomaa Børge G Nordestgaard Bu B Yeap Astrid Fletcher Olle Melander Lewis H Kuller Beverley Balkau Michael Marmot Wolfgang Koenig Edoardo Casiglia Cyrus Cooper Volker Arndt Oscar H Franco Patrik Wennberg John Gallacher Agustín Gómez de la Cámara Henry Völzke Christina C Dahm Caroline E Dale Manuela M Bergmann Carlos J Crespo Yvonne T van der Schouw Rudolf Kaaks Leon A Simons Pagona Lagiou Josje D Schoufour Jolanda M A Boer Timothy J Key Beatriz Rodriguez Conchi Moreno-Iribas Karina W Davidson James O Taylor Carlotta Sacerdote Robert B Wallace J Ramon Quiros Rosario Tumino Dan G Blazer Allan Linneberg Makoto Daimon Salvatore Panico Barbara Howard Guri Skeie Timo Strandberg Elisabete Weiderpass Paul J Nietert Bruce M Psaty Daan Kromhout Elena Salamanca-Fernandez Stefan Kiechl Harlan M Krumholz Sara Grioni Domenico Palli José M Huerta Jackie Price Johan Sundström Larraitz Arriola Hisatomi Arima Ruth C Travis Demosthenes B Panagiotakos Anna Karakatsani Antonia Trichopoulou Tilman Kühn Diederick E Grobbee Elizabeth Barrett-Connor Natasja van Schoor Heiner Boeing Kim Overvad Jussi Kauhanen Nick Wareham Claudia Langenberg Nita Forouhi Maria Wennberg Jean-Pierre Després Mary Cushman Jackie A Cooper Carlos J Rodriguez Masaru Sakurai Jonathan E Shaw Matthew Knuiman Trudy Voortman Christa Meisinger Anne Tjønneland Hermann Brenner Luigi Palmieri Jean Dallongeville Eric J Brunner Gerd Assmann Maurizio Trevisan Richard F Gillum Ian Ford Naveed Sattar Mariana Lazo Simon G Thompson Pietro Ferrari David A Leon George Davey Smith Richard Peto Rod Jackson Emily Banks Emanuele Di Angelantonio John Danesh

Lancet 2018 04;391(10129):1513-1523

Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(18)30134-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899998PMC
April 2018

Maternal iron status during pregnancy and respiratory and atopic outcomes in the offspring: a Mendelian randomisation study.

BMJ Open Respir Res 2018 30;5(1):e000275. Epub 2018 Mar 30.

Centre for Primary Care and Public Health, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1136/bmjresp-2018-000275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890059PMC
March 2018

Genetically elevated gamma-glutamyltransferase and Alzheimer's disease.

Exp Gerontol 2018 06 2;106:61-66. Epub 2018 Mar 2.

MRC Biostatistics Unit, University of Cambridge, Cambridge, Cambridgeshire CB2 0SR, UK; Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, Cambridgeshire CB1 8RN, UK.

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http://dx.doi.org/10.1016/j.exger.2018.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915296PMC
June 2018

Body mass index and breast cancer survival: a Mendelian randomization analysis.

Authors:
Qi Guo Stephen Burgess Constance Turman Manjeet K Bolla Qin Wang Michael Lush Jean Abraham Kristiina Aittomäki Irene L Andrulis Carmel Apicella Volker Arndt Myrto Barrdahl Javier Benitez Christine D Berg Carl Blomqvist Stig E Bojesen Bernardo Bonanni Judith S Brand Hermann Brenner Annegien Broeks Barbara Burwinkel Carlos Caldas Daniele Campa Federico Canzian Jenny Chang-Claude Stephen J Chanock Suet-Feung Chin Fergus J Couch Angela Cox Simon S Cross Cezary Cybulski Kamila Czene Hatef Darabi Peter Devilee W Ryan Diver Alison M Dunning Helena M Earl Diana M Eccles Arif B Ekici Mikael Eriksson D Gareth Evans Peter A Fasching Jonine Figueroa Dieter Flesch-Janys Henrik Flyger Susan M Gapstur Mia M Gaudet Graham G Giles Gord Glendon Mervi Grip Jacek Gronwald Lothar Haeberle Christopher A Haiman Per Hall Ute Hamann Susan Hankinson Jaana M Hartikainen Alexander Hein Louise Hiller Frans B Hogervorst Bernd Holleczek Maartje J Hooning Robert N Hoover Keith Humphreys David J Hunter Anika Hüsing Anna Jakubowska Arja Jukkola-Vuorinen Rudolf Kaaks Maria Kabisch Vesa Kataja Julia A Knight Linetta B Koppert Veli-Matti Kosma Vessela N Kristensen Diether Lambrechts Loic Le Marchand Jingmei Li Annika Lindblom Sara Lindström Jolanta Lissowska Jan Lubinski Mitchell J Machiela Arto Mannermaa Siranoush Manoukian Sara Margolin Federik Marme John W M Martens Catriona McLean Primitiva Menéndez Roger L Milne Anna Marie Mulligan Taru A Muranen Heli Nevanlinna Patrick Neven Sune F Nielsen Børge G Nordestgaard Janet E Olson Jose I A Perez Paolo Peterlongo Kelly-Anne Phillips Christopher J Poole Katri Pylkäs Paolo Radice Nazneen Rahman Thomas Rüdiger Anja Rudolph Elinor J Sawyer Fredrick Schumacher Petra Seibold Caroline Seynaeve Mitul Shah Ann Smeets Melissa C Southey Rob A E M Tollenaar Ian Tomlinson Helen Tsimiklis Hans-Ulrich Ulmer Celine Vachon Ans M W van den Ouweland Laura J Van't Veer Hans Wildiers Walter Willett Robert Winqvist M Pilar Zamora Georgia Chenevix-Trench Thilo Dörk Douglas F Easton Montserrat García-Closas Peter Kraft John L Hopper Wei Zheng Marjanka K Schmidt Paul D P Pharoah

Int J Epidemiol 2017 12;46(6):1814-1822

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1093/ije/dyx131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837506PMC
December 2017

Modifiable pathways in Alzheimer's disease: Mendelian randomisation analysis.

BMJ 2017 12 6;359:j5375. Epub 2017 Dec 6.

Stroke Research Group, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717765PMC
http://dx.doi.org/10.1136/bmj.j5375DOI Listing
December 2017

Association between a functional interleukin 6 receptor genetic variant and risk of depression and psychosis in a population-based birth cohort.

Brain Behav Immun 2018 03 2;69:264-272. Epub 2017 Dec 2.

Department of Psychiatry, University of Cambridge, Cambridge, UK; Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK.

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http://dx.doi.org/10.1016/j.bbi.2017.11.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871397PMC
March 2018

Extending the MR-Egger method for multivariable Mendelian randomization to correct for both measured and unmeasured pleiotropy.

Stat Med 2017 Dec 27;36(29):4705-4718. Epub 2017 Sep 27.

Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1002/sim.7492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725762PMC
December 2017

Mendelian randomization with fine-mapped genetic data: Choosing from large numbers of correlated instrumental variables.

Genet Epidemiol 2017 12 25;41(8):714-725. Epub 2017 Sep 25.

Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1002/gepi.22077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725678PMC
December 2017

Genetically-Predicted Adult Height and Alzheimer's Disease.

J Alzheimers Dis 2017 ;60(2):691-698

Stroke Research Group, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.3233/JAD-170528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037293PMC
April 2018

Erratum to: Interpreting findings from Mendelian randomization using the MR-Egger method.

Eur J Epidemiol 2017 05;32(5):391-392

Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1007/s10654-017-0276-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828068PMC
May 2017

Difficulties in Testing the Instrument Strength Independent of Direct Effect Assumption in Mendelian Randomization.

JAMA Cardiol 2017 08;2(8):929-930

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England.

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http://dx.doi.org/10.1001/jamacardio.2017.1572DOI Listing
August 2017

Interpreting findings from Mendelian randomization using the MR-Egger method.

Eur J Epidemiol 2017 05 19;32(5):377-389. Epub 2017 May 19.

Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1007/s10654-017-0255-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506233PMC
May 2017

Mendelian Randomization Implicates High-Density Lipoprotein Cholesterol-Associated Mechanisms in Etiology of Age-Related Macular Degeneration.

Ophthalmology 2017 08 26;124(8):1165-1174. Epub 2017 Apr 26.

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1016/j.ophtha.2017.03.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526457PMC
August 2017

MendelianRandomization: an R package for performing Mendelian randomization analyses using summarized data.

Int J Epidemiol 2017 12;46(6):1734-1739

Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1093/ije/dyx034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510723PMC
December 2017