Stephen Brand

Stephen Brand

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Stephen Brand

Stephen Brand

Publications by authors named "Stephen Brand"

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36Publications

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The proteasome as a target for protozoan parasites.

Expert Opin Ther Targets 2019 11 4;23(11):903-914. Epub 2019 Nov 4.

Department of Biochemistry and Molecular Biology Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, Australia.

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http://dx.doi.org/10.1080/14728222.2019.1685981DOI Listing
November 2019

A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors.

J Med Chem 2018 09 12;61(18):8374-8389. Epub 2018 Sep 12.

Drug Discovery Unit, Wellcome Centre for Anti-Infectives Research, Division of Biological Chemistry and Drug Discovery, School of Life Sciences , University of Dundee , Dundee , DD1 5EH , United Kingdom.

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http://dx.doi.org/10.1021/acs.jmedchem.8b00884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167002PMC
September 2018

Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani.

ACS Infect Dis 2017 10 2;3(10):718-727. Epub 2017 Oct 2.

Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.

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http://dx.doi.org/10.1021/acsinfecdis.7b00047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663395PMC
October 2017

Enantiomerically enriched, polycrystalline molecular sieves.

Proc Natl Acad Sci U S A 2017 05 1;114(20):5101-5106. Epub 2017 May 1.

Chemical Engineering, California Institute of Technology, Pasadena, CA 91125;

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http://dx.doi.org/10.1073/pnas.1704638114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441830PMC
May 2017

Validation of N-myristoyltransferase as Potential Chemotherapeutic Target in Mammal-Dwelling Stages of Trypanosoma cruzi.

PLoS Negl Trop Dis 2016 Apr 29;10(4):e0004540. Epub 2016 Apr 29.

The Border Biomedical Research Center, Department of Biological Sciences, University of Texas at El Paso, El Paso, Texas, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0004540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851402PMC
April 2016

Facile Synthesis, Characterization, and Catalytic Behavior of a Large-Pore Zeolite with the IWV Framework.

Chemistry 2016 Mar 2;22(12):4022-9. Epub 2016 Feb 2.

Chemical Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.

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http://dx.doi.org/10.1002/chem.201504717DOI Listing
March 2016

Development of a Fluorescence-based Trypanosoma cruzi CYP51 Inhibition Assay for Effective Compound Triaging in Drug Discovery Programmes for Chagas Disease.

PLoS Negl Trop Dis 2015 Sep 22;9(9):e0004014. Epub 2015 Sep 22.

Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee, United Kingdom.

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http://dx.doi.org/10.1371/journal.pntd.0004014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578769PMC
September 2015

Prevention of chronic renal allograft rejection by soluble CD83.

Transplantation 2010 Dec;90(12):1278-85

Department of Surgery, University of Western Ontario, London, ON, Canada.

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http://dx.doi.org/10.1097/TP.0b013e318200005cDOI Listing
December 2010

Structural identification of recombinant human CD83 mutant variant as a potent therapeutic protein.

Protein Expr Purif 2010 Oct 8;73(2):140-6. Epub 2010 Jun 8.

Department of Chemical Engineering, University of Waterloo, Waterloo, Ontario, Canada N2L 3G1.

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http://dx.doi.org/10.1016/j.pep.2010.05.016DOI Listing
October 2010

Assessment of the anterior maxilla in orthodontic patients using upper anterior occlusal radiographs and dental panoramic tomography: a comparison.

Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010 May 22;109(5):765-74. Epub 2010 Jan 22.

Specialist Orthodontist, Total Orthodontics, Haywards Heath, United Kingdom.

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http://linkinghub.elsevier.com/retrieve/pii/S107921040900778
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http://dx.doi.org/10.1016/j.tripleo.2009.10.016DOI Listing
May 2010

Bioprocess development for production, purification, and structural characterization of recombinant hCD83ext as a potential therapeutic protein.

Protein Expr Purif 2009 May 13;65(1):92-9. Epub 2008 Dec 13.

Department of Chemical Engineering, University of Waterloo, 200 University Ave. West, Waterloo, Ont. N2L3G1, Canada.

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http://dx.doi.org/10.1016/j.pep.2008.12.005DOI Listing
May 2009

A large-scale examination of the nature and efficacy of teachers' practices to engage parents: assessment, parental contact, and student-level impact.

J Sch Psychol 2008 Aug 21;46(4):477-505. Epub 2007 Dec 21.

School of Education, University of Rhode Island, Kingston, RI 02881, USA.

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http://dx.doi.org/10.1016/j.jsp.2007.11.001DOI Listing
August 2008

A fluorous, Pummerer cyclative-capture strategy for the synthesis of N-heterocycles.

Chemistry 2007 ;13(4):1032-46

Department of Chemistry, The Joseph Black Building, The University of Glasgow, Glasgow G12 8QQ, Scotland.

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http://dx.doi.org/10.1002/chem.200601429DOI Listing
March 2007

Solid phase approaches to N-heterocycles using a sulfur linker cleaved by SmI2.

J Org Chem 2006 Aug;71(17):6497-507

Department of Chemistry, Joseph Black Building, University of Glasgow, Glasgow, G12 8QQ, UK.

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http://dx.doi.org/10.1021/jo060940nDOI Listing
August 2006

Combination therapy with epidermal growth factor and gastrin increases beta-cell mass and reverses hyperglycemia in diabetic NOD mice.

Diabetes 2005 Sep;54(9):2596-601

Heritage Medical Research Centre, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.2337/diabetes.54.9.2596DOI Listing
September 2005

Combination therapy with epidermal growth factor and gastrin induces neogenesis of human islet {beta}-cells from pancreatic duct cells and an increase in functional {beta}-cell mass.

J Clin Endocrinol Metab 2005 Jun 15;90(6):3401-9. Epub 2005 Mar 15.

430 Heritage Medical Research Center, University of Alberta, Edmonton, Alberta, Canada T6G 2S2.

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http://dx.doi.org/10.1210/jc.2004-0761DOI Listing
June 2005

A fluorous-phase pummerer cyclative-capture strategy for the synthesis of nitrogen heterocycles.

Angew Chem Int Ed Engl 2005 Jan;44(3):452-5

Department of Chemistry, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, Scotland, UK.

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http://doi.wiley.com/10.1002/anie.200461930
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http://dx.doi.org/10.1002/anie.200461930DOI Listing
January 2005

The first Pummerer cyclisations on solid phase. Convenient construction of oxindoles enabled by a sulfur-link to resin.

Chem Commun (Camb) 2003 Sep(18):2380-1

Department of Chemistry, The Joseph Black Building, University of Glasgow, Glasgow, Scotland, UK G12 8QQ.

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http://dx.doi.org/10.1039/b307586aDOI Listing
September 2003

Efficient synthesis of 3-aminocyclobut-2-en-1-ones: squaramide surrogates as potent VLA-4 antagonists.

Org Lett 2003 Jun;5(13):2343-6

Medicinal Chemistry, Celltech Group plc, 216 Bath Road, Slough SL1 4EN, UK.

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http://dx.doi.org/10.1021/ol034701nDOI Listing
June 2003

An Enantioselective Ring Expansion Route Leading to Furanose and Pyranose Nucleosides Featuring Spirodiketopiperazines at the Anomeric Position.

J Org Chem 1999 Mar;64(6):2010-2025

Evans Chemical Laboratories, The Ohio State University, Columbus, Ohio 43210.

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http://dx.doi.org/10.1021/jo982259uDOI Listing
March 1999