Publications



Exercise's effect on mobility disability in older adults with and without obesity: The LIFE study randomized clinical trial.
Obesity (Silver Spring) 2017 Jul;25(7):1199-1205
Department of Aging and Geriatric Research, Institute on Aging, College of Medicine, University of Florida, Gainesville, Florida, USA.

Cellular senescence biomarker p16INK4a+ cell burden in thigh adipose is associated with poor physical function in older women.
J Gerontol A Biol Sci Med Sci 2017 Jun 27. Epub 2017 Jun 27.
Sticht Center for Healthy Aging and Alzheimer's Prevention, Internal Medicine - Gerontology and Geriatric Medicine, Wake Forest School of Medicine (WFSM), 1 Medical Center Blvd, Winston-Salem, NC 27157.







Effects of Longitudinal Glucose Exposure on Cognitive and Physical Function: Results from the Action for Health in Diabetes Movement and Memory Study.
J Am Geriatr Soc 2017 Jan 27;65(1):137-145. Epub 2016 Sep 27.
Department of Section on Gerontology and Geriatric Medicine, Department of Internal Medicine, School of Medicine, Wake Forest University, Winston-Salem, North Carolina.

Effect of Statin Use on Mobility Disability and its Prevention in At-risk Older Adults: The LIFE Study.
J Gerontol A Biol Sci Med Sci 2016 Nov 17;71(11):1519-1524. Epub 2016 Mar 17.
Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Sticht Center on Aging, Wake Forest School of Medicine, Winston-Salem, North Carolina.


Effect of Intensive Chemotherapy on Physical, Cognitive, and Emotional Health of Older Adults with Acute Myeloid Leukemia.
J Am Geriatr Soc 2016 Oct 14;64(10):1988-1995. Epub 2016 Sep 14.
Section on Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.

A Multidimensional Risk Score to Predict All-Cause Hospitalization in Community-Dwelling Older Individuals With Obstructive Lung Disease.
J Am Med Dir Assoc 2016 Jun 23;17(6):508-13. Epub 2016 Feb 23.
NUTRIM School for Nutrition and Translational Research in Metabolism, Department of Respiratory Medicine, Maastricht University Medical Centre+, Maastricht, The Netherlands.



Association of Muscle Mass, Area, and Strength With Incident Diabetes in Older Adults: The Health ABC Study.
J Clin Endocrinol Metab 2016 Apr 1;101(4):1847-55. Epub 2016 Mar 1.
Department of Family Medicine and Public Health (B.A.L., M.H.C., I.X.), and Department of Medicine (J.H.I.), University of California, San Diego, San Diego, California 92093-0628; Department of Pathology and Laboratory Medicine (C.L.W.), College of Medicine, University of Vermont, Burlington, Vermont 05446; Wake Forest University and School of Medicine (S.B.K.), Winston-Salem, North Carolina 27157; Graduate School of Public Health (E.S.S.), University of Pittsburgh, Pittsburgh, Pennsylvania 15219; Division of General Internal Medicine (A.M.K.), Department of Epidemiology and Biostatistics (A.V.S.), University of California, San Francisco, San Francisco, California 94143; University of Pittsburgh School of Medicine and Veterans Affairs Pittsburgh Healthcare System (L.F.F.), Pittsburgh, Pennsylvania 15261; and National Institute on Aging (T.B.H.), Bethesda, Maryland 20892.

Self-reported Mobility in Older Patients Predicts Early Postoperative Outcomes after Elective Noncardiac Surgery.
Anesthesiology 2016 Apr;124(4):815-25
From the Department of Internal Medicine, Section of General Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina (S.K.); Sticht Center on Aging, Wake Forest School of Medicine, Winston-Salem, North Carolina (A.P.M., X.I.L., S.B.K., W.J.R., L.G.); Department of Health and Exercise Science, Wake Forest University, Winston-Salem, North Carolina (A.P.M., W.J.R.); Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, North Carolina (L.R., C.R., L.G.); Division of Public Health Sciences, Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina (X.I.L.); Department of Internal Medicine, Section of Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina (S.B.K.); Department of Internal Medicine, Section of Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina (L.G.); and Hypertension and Vascular Research Center, Wake Forest School of Medicine, Winston-Salem, North Carolina (L.G.).





Association of Serum Erythropoietin With Cardiovascular Events, Kidney Function Decline, and Mortality: The Health Aging and Body Composition Study.
Circ Heart Fail 2016 Jan;9(1):e002124
From the Division of Nephrology, Department of Medicine, Tufts Medical Center, Boston, MA (P.S.G., M.J.S.); Kidney Research Institute (R.K.) and Department of Anesthesiology and Pain Medicine (K.V.P.), University of Washington, Seattle; Sticht Center on Aging, Wake Forest School of Medicine, Winston-Salem, NC (S.B.K.); Section of Nephrology, Department of Medicine, Yale University School of Medicine, New Haven, CT (C.R.P.); Nephrology Section, Veterans Affairs San Diego Healthcare System and Division of Nephrology and Preventive Medicine, University of California, San Diego (J.H.I.); Renal Section, VA Pittsburgh Healthcare System (L.F.F.) and Department of Epidemiology, Graduate School of Public Health (A.B.N.), University of Pittsburgh, PA; Department of Epidemiology, Biostatistics, and Medicine, University of California, San Francisco (M.G.S.); Department of General Internal Medicine, San Francisco VA Medical Center, CA (M.G.S.); and Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MA (T.B.H.).



Respirometric Profiling of Muscle Mitochondria and Blood Cells Are Associated With Differences in Gait Speed Among Community-Dwelling Older Adults.
J Gerontol A Biol Sci Med Sci 2015 Nov 16;70(11):1394-9. Epub 2014 Jul 16.
Sticht Center on Aging and Department of Internal Medicine, Section on Gerontology and Geriatrics, Wake Forest School of Medicine, Winston-Salem, North Carolina.


Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry.
Hum Mol Genet 2015 Aug 20;24(16):4728-38. Epub 2015 May 20.
Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Department of Nutrition, Harvard Chan School of Public Health, Boston, MA, USA, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden,


Increased cardiovascular stiffness and impaired age-related functional status.
J Gerontol A Biol Sci Med Sci 2015 May 24;70(5):545-53. Epub 2014 Jun 24.
Section of Cardiology, Department of Internal Medicine, Section of Radiology, Wake Forest School of Medicine, Winston-Salem, North Carolina.



Genetic and environmental factors are associated with serum 25-hydroxyvitamin D concentrations in older African Americans.
J Nutr 2015 Apr 25;145(4):799-805. Epub 2015 Feb 25.
Division of Nutritional Sciences, Cornell University, Ithaca, NY; Department of Healthcare Policy and Research, Division of Biostatistics and Epidemiology, Weill Cornell Medical College, New York, NY


Protein and healthy aging.
Am J Clin Nutr 2015 Apr 29. Epub 2015 Apr 29.
From the Department of Nutrition and Metabolism, University of Texas Medical Branch, Galveston, TX (DP-J); the Department of Nutrition Science, Purdue University, West Lafayette, IN (WWC); the Jean Mayer USDA Human Nutrition Research Center, Tufts University, Boston, MA (PFJ); Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC (SBK); the Department of Medicine, Boston University, Boston, MA (LLM); the Department of Nutritional Sciences, University of Connecticut, Storrs, CT (NRR); and the NUTRIM School for Nutrition, Toxicology, and Metabolism, Maastricht University, Maastricht, The Netherlands (LJCvL).


A long-term intensive lifestyle intervention and physical function: the look AHEAD Movement and Memory Study.
Obesity (Silver Spring) 2015 Jan 29;23(1):77-84. Epub 2014 Nov 29.
Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.


Meta-analysis of genome-wide association studies for circulating phylloquinone concentrations.
Am J Clin Nutr 2014 Dec 8;100(6):1462-9. Epub 2014 Oct 8.
From the Nutrition and Genomics Laboratory (HSD, CES, KR, and JMO), Vitamin K Laboratory (MKS and SLB), Jean Mayer U.S. Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA; the Translational Gerontology Branch (TT), Laboratory of Neurogenetics (MAN), National Institute on Aging, Baltimore, MD; the Department of Nutrition, Harvard School of Public Health, Boston, MA (AH); the Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN (TJW); the Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA (XG and JY); the Department of Public Health Sciences (YL), Sticht Center on Aging (SBK), Wake Forest Medical Center, Winston-Salem, NC; Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, CA (DL); the Department of Biostatistics, University of Washington, Seattle, WA (WCJ); Boston University and National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA (EJB); the Department of Medicine, Boston University School of Medicine, Boston, MA (EJB); New York Academy of Medicine, New York, NY (DSS); the Department of Epidemiology, Centro Nacional Investigaciones Cardiovasculares (CNIC), Madrid, Spain (JMO); and Instituto Madrileño de Estudios Avanzados en Alimentación (IMDEA-FOOD), Madrid, Spain (JMO). Any opinions, findings, conclusions, or recommendations expressed in this publication are those of the author(s) and do not necessarily reflect the view of the U.S. Department of Agriculture.

Sensory and motor peripheral nerve function and incident mobility disability.
J Am Geriatr Soc 2014 Dec 8;62(12):2273-9. Epub 2014 Dec 8.
Spaulding Rehabilitation Hospital, Cambridge, Massachusetts; School of Public Health, Boston University, Boston, Massachusetts.

Age-related variations in the methylome associated with gene expression in human monocytes and T cells.
Nat Commun 2014 Nov 18;5:5366. Epub 2014 Nov 18.
Departments of Epidemiology & Prevention, and Biostatistics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA.

Serum bicarbonate concentrations and kidney disease progression in community-living elders: the Health, Aging, and Body Composition (Health ABC) Study.
Am J Kidney Dis 2014 Oct 18;64(4):542-9. Epub 2014 Jun 18.
Division of Nephrology and Hypertension, Department of Medicine, University of California, San Diego, CA; Nephrology Section, Veterans Affairs San Diego Healthcare System, San Diego, CA; Division of Preventive Medicine, Department of Family and Preventive Medicine, University of California San Diego, San Diego, CA. Electronic address:

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.
Nat Commun 2014 Oct 28;5:5068. Epub 2014 Oct 28.
1] NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London EC1M 6BQ, UK [2] Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, London EC1M6BQ, UK.

Long-term impact of behavioral weight loss intervention on cognitive function.
J Gerontol A Biol Sci Med Sci 2014 Sep 11;69(9):1101-8. Epub 2014 Mar 11.
Section on Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.


Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study.
Lancet Diabetes Endocrinol 2014 Sep 25;2(9):719-29. Epub 2014 Jun 25.
Population, Policy and Practice, UCL Institute of Child Health, London, UK; School of Population Health, Sansom Institute for Health Research, University of South Australia, Adelaide, SA, Australia; South Australian Health and Medical Research Institute, Adelaide, SA, Australia. Electronic address:

Weight change, body composition, and risk of mobility disability and mortality in older adults: a population-based cohort study.
J Am Geriatr Soc 2014 Aug 15;62(8):1476-1483. Epub 2014 Jul 15.
Laboratory of Epidemiology, and Population Sciences, Intramural Research Program, National Institute on Aging, Bethesda, MD.

Urinary kidney injury molecule 1 (KIM-1) and interleukin 18 (IL-18) as risk markers for heart failure in older adults: the Health, Aging, and Body Composition (Health ABC) Study.
Am J Kidney Dis 2014 Jul 18;64(1):49-56. Epub 2014 Mar 18.
Department of Medicine, University of California, San Francisco, San Francisco, CA; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA; Department of General Internal Medicine, San Francisco Veterans Affairs Medical Center, San Francisco, CA. Electronic address:

Genome-wide association analysis identifies six new loci associated with forced vital capacity.
Nat Genet 2014 Jul 15;46(7):669-77. Epub 2014 Jun 15.
1] Epidemiology Branch, National Institute of Environmental Health Sciences, US National Institutes of Health, US Department of Health and Human Services, Research Triangle Park, North Carolina, USA. [2].

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function.
PLoS One 2014 1;9(7):e100776. Epub 2014 Jul 1.
Division of Nutritional Sciences, Cornell University, Ithaca, New York, United States of America; Department of Health Care Policy and Research, Division of Biostatistics and Epidemiology, Weill Cornell Medical College, New York, New York, United States of America.


Sleep-wake disturbances in sedentary community-dwelling elderly adults with functional limitations.
J Am Geriatr Soc 2014 Jun 2;62(6):1064-72. Epub 2014 Jun 2.
Clinical Epidemiology Research Center, Veterans Affairs Connecticut, West Haven, Connecticut; Department of Medicine, School of Medicine, Yale University, New Haven, Connecticut.

Associations of BMI and adipose tissue area and density with incident mobility limitation and poor performance in older adults.
Am J Clin Nutr 2014 May 12;99(5):1059-65. Epub 2014 Feb 12.
Laboratory of Epidemiology, and Population Sciences, Intramural Research Program, National Institute on Aging, Bethesda, MD (RAM, IR, and TBH); the Sections on Comparative Medicine Pathology, Radiology (TCR), and Gerontology and Geriatrics (SBK), Sticht Center on Aging, Wake Forest School of Medicine, Winston-Salem, NC; the Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA (HNA); the Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA (ABN); the Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN (SS); the Center for Aging and Population Health, Department of Medicine, University of Pittsburgh, Pittsburgh, PA (BHG); and the Translational Gerontology Branch, Intramural Research Program, National Institute on Aging, Baltimore, MD (EMS).






Respiratory impairment and dyspnea and their associations with physical inactivity and mobility in sedentary community-dwelling older persons.
J Am Geriatr Soc 2014 Apr 17;62(4):622-8. Epub 2014 Mar 17.
Veterans Affairs Connecticut, West Haven, Connecticut; Department of Medicine, School of Medicine, Yale University, New Haven, Connecticut.


Genome-wide association of body fat distribution in African ancestry populations suggests new loci.
PLoS Genet 2013 15;9(8):e1003681. Epub 2013 Aug 15.
Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.

Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats.
Cardiovasc Endocrinol 2012 Sep;1(3):49-58
Department of Anesthesiology, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina, USA ; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina, USA ; Hypertension and Vascular Research Center, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina, USA.

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