Stephen A Chappell

Stephen A Chappell

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Stephen A Chappell

Stephen A Chappell

Publications by authors named "Stephen A Chappell"

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Considerations in the Use of Codon Optimization for Recombinant Protein Expression.

Methods Mol Biol 2018 ;1850:275-288

Leidos, San Diego, CA, USA.

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http://dx.doi.org/10.1007/978-1-4939-8730-6_18DOI Listing
May 2019

A critical analysis of codon optimization in human therapeutics.

Trends Mol Med 2014 Nov 25;20(11):604-13. Epub 2014 Sep 25.

Department of Cell and Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://www.cell.com/trends/molecular-medicine/pdf/S1471-4914
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http://dx.doi.org/10.1016/j.molmed.2014.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253638PMC
November 2014

Analysis of ribosomal shunting during translation initiation in eukaryotic mRNAs.

Methods Enzymol 2007 ;429:323-54

Department of Neurobiology, The Scripps Research Institute, La Jolla, California, USA.

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http://dx.doi.org/10.1016/S0076-6879(07)29015-9DOI Listing
December 2007

Ribosomal tethering and clustering as mechanisms for translation initiation.

Proc Natl Acad Sci U S A 2006 Nov 16;103(48):18077-82. Epub 2006 Nov 16.

Department of Neurobiology, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.0608212103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1838709PMC
November 2006

Ribosomal shunting mediated by a translational enhancer element that base pairs to 18S rRNA.

Proc Natl Acad Sci U S A 2006 Jun 12;103(25):9488-93. Epub 2006 Jun 12.

Department of Neurobiology, The Scripps Research Institute, and The Skaggs Institute for Chemical Biology, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.0603597103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1480434PMC
June 2006

An mRNA-rRNA base-pairing mechanism for translation initiation in eukaryotes.

Nat Struct Mol Biol 2006 Jan 11;13(1):30-4. Epub 2005 Dec 11.

Department of Neurobiology, The Scripps Research Institute, and The Skaggs Institute for Chemical Biology, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/nsmb1031DOI Listing
January 2006

Biochemical and functional analysis of a 9-nt RNA sequence that affects translation efficiency in eukaryotic cells.

Proc Natl Acad Sci U S A 2004 Jun 21;101(26):9590-4. Epub 2004 Jun 21.

Department of Neurobiology, The Scripps Research Institute, and The Skaggs Institute for Chemical Biology, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.0308759101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC470719PMC
June 2004

The internal ribosome entry site (IRES) contained within the RNA-binding motif protein 3 (Rbm3) mRNA is composed of functionally distinct elements.

J Biol Chem 2003 Sep 24;278(36):33793-800. Epub 2003 Jun 24.

Department of Neurobiology, The Scripps Research Institute, and The Skaggs Institute for Chemical Biology, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1074/jbc.M303495200DOI Listing
September 2003