Publications by authors named "Stephanie Roessler"

62Publications

Integrative genomics highlights opportunities for innovative therapies targeting the tumor microenvironment in gallbladder cancer.

Authors:
Stephanie Roessler Julien Edeline Peter Schirmacher Cédric Coulouarn

J Hepatol 2021 Feb 16. Epub 2021 Feb 16.

Inserm, Univ Rennes 1, UMR_S 1242, COSS (Chemistry, Oncogenesis Stress Signaling), Centre de Lutte contre le Cancer Eugène Marquis, Rennes, France. Electronic address:

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February 2021

Integrative analysis reveals early and distinct genetic and epigenetic changes in intraductal papillary and tubulopapillary cholangiocarcinogenesis.

Authors:
Benjamin Goeppert Damian Stichel Reka Toth Sarah Fritzsche Moritz Anton Loeffler Anna Melissa Schlitter Olaf Neumann Yassen Assenov Monika Nadja Vogel Arianeb Mehrabi Katrin Hoffmann Bruno Köhler Christoph Springfeld Dieter Weichenhan Christoph Plass Irene Esposito Peter Schirmacher Andreas von Deimling Stephanie Roessler

Gut 2021 Jan 19. Epub 2021 Jan 19.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany

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January 2021

Prohibitin, STAT3 and SH2D4A physically and functionally interact in tumor cell mitochondria.

Authors:
Carolin Ploeger Thorben Huth Raisatun Nisa Sugiyanto Stefan Pusch Benjamin Goeppert Stephan Singer Redouane Tabti Ingrid Hausser Peter Schirmacher Laurent Désaubry Stephanie Roessler

Cell Death Dis 2020 11 30;11(11):1023. Epub 2020 Nov 30.

Department of General Pathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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November 2020

Loss of miR-192-5p initiates a hyperglycolysis and stemness positive feedback in hepatocellular carcinoma.

Authors:
Yuanzhuo Gu Fubo Ji Niya Liu Yongzhi Zhao Xiyang Wei Shiyuan Hu Wei Jia Xin Wei Wang Anuradha Budhu Juling Ji Bin Zhao Stephanie Roessler Xin Zheng Junfang Ji

J Exp Clin Cancer Res 2020 Nov 30;39(1):268. Epub 2020 Nov 30.

MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, Zhejiang Province, China.

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November 2020

YAP Orchestrates Heterotypic Endothelial Cell Communication via HGF/c-MET Signaling in Liver Tumorigenesis.

Authors:
Stefan Thomann Sofia M E Weiler Simone Marquard Fabian Rose Claudia R Ball Marcell Tóth Teng Wei Carsten Sticht Sarah Fritzsche Stephanie Roessler Carolina De La Torre Eduard Ryschich Olga Ermakova Carolin Mogler Daniel Kazdal Norbert Gretz Hanno Glimm Eugen Rempel Peter Schirmacher Kai Breuhahn

Cancer Res 2020 Dec 21;80(24):5502-5514. Epub 2020 Oct 21.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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December 2020

Epigenome-wide analysis of methylation changes in the sequence of gallstone disease, dysplasia, and gallbladder cancer.

Authors:
Johannes Brägelmann Carol Barahona Ponce Katherine Marcelain Stephanie Roessler Benjamin Goeppert Ivan Gallegos Alicia Colombo Verónica Sanhueza Erik Morales María Teresa Rivera Gonzalo de Toro Alejandro Ortega Bettina Müller Fernando Gabler Dominique Scherer Melanie Waldenberger Eva Reischl Felix Boekstegers Valentina Garate-Calderon Sinan U Umu Trine B Rounge Odilia Popanda Justo Lorenzo Bermejo

Hepatology 2020 Oct 5. Epub 2020 Oct 5.

Institute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany.

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October 2020

RNA Sequencing of Hepatobiliary Cancer Cell Lines: Data and Applications to Mutational and Transcriptomic Profiling.

Authors:
Dominique Scherer Marcela Dávila Dávila López Benjamin Goeppert Sanna Abrahamsson Rosa González González Silos Igor Nova Katherine Marcelain Juan C Roa David Ibberson Sinan U Umu Trine Ballestad Rounge Stephanie Roessler Justo Lorenzo Bermejo

Cancers (Basel) 2020 Sep 3;12(9). Epub 2020 Sep 3.

Institute of Medical Biometry and Informatics, University of Heidelberg, 69120 Heidelberg, Germany.

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September 2020

Synchronised infection identifies early rate-limiting steps in the hepatitis B virus life cycle.

Authors:
Anindita Chakraborty Chunkyu Ko Christin Henning Aaron Lucko James M Harris Fuwang Chen Xiaodong Zhuang Jochen M Wettengel Stephanie Roessler Ulrike Protzer Jane A McKeating

Cell Microbiol 2020 12 28;22(12):e13250. Epub 2020 Sep 28.

Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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December 2020

Spatially resolved analysis of FFPE tissue proteomes by quantitative mass spectrometry.

Authors:
Katarzyna Buczak Joanna M Kirkpatrick Felicia Truckenmueller Deolinda Santinha Lino Ferreira Stephanie Roessler Stephan Singer Martin Beck Alessandro Ori

Nat Protoc 2020 09 31;15(9):2956-2979. Epub 2020 Jul 31.

Leibniz Institute on Aging-Fritz Lipmann Institute (FLI), Jena, Germany.

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September 2020

Transcriptome profiling identifies TIGIT as a marker of T cell exhaustion in liver cancer.

Authors:
Dmitrij Ostroumov Steven Duong Jessica Wingerath Norman Woller Michael P Manns Kai Timrott Moritz Kleine Wolf Ramackers Stephanie Roessler Sven Nahnsen Stefan Czemmel Oliver Dittrich-Breiholz Tobias Eggert Florian Kühnel Thomas C Wirth

Hepatology 2020 Jul 27. Epub 2020 Jul 27.

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, 30625, Hannover, Germany.

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July 2020

miRNA profiling of biliary intraepithelial neoplasia reveals stepwise tumorigenesis in distal cholangiocarcinoma via the miR-451a/ATF2 axis.

Authors:
Moritz A Loeffler Jun Hu Martina Kirchner Xiyang Wei Yi Xiao Thomas Albrecht Carolina De La Torre Carsten Sticht Jesus M Banales Monika N Vogel Anita Pathil-Warth Arianeb Mehrabi Katrin Hoffmann Christian Rupp Bruno Köhler Christoph Springfeld Peter Schirmacher Junfang Ji Stephanie Roessler Benjamin Goeppert

J Pathol 2020 11 15;252(3):239-251. Epub 2020 Sep 15.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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November 2020

MiR-125b Loss Activated HIF1α/pAKT Loop, Leading to Transarterial Chemoembolization Resistance in Hepatocellular Carcinoma.

Authors:
Xiyang Wei Lei Zhao Ruizhe Ren Fubo Ji Shuting Xue Jianjuan Zhang Zhaogang Liu Zhao Ma Xin W Wang Linda Wong Niya Liu Jiong Shi Xing Guo Stephanie Roessler Xin Zheng Junfang Ji

Hepatology 2020 Jul 1. Epub 2020 Jul 1.

MOE Key Laboratory of Biosystems Homeostasis & Protection, Life Sciences Institute, Zhejiang University, Hangzhou, China.

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July 2020

Impact of Type 2 Diabetes on Oncologic Outcomes of Hepatocellular Carcinomas in Non-Cirrhotic, Non-alcoholic Steatohepatitis: a Matched-Pair Analysis.

Authors:
Adrian T Billeter Philip C Müller Thomas Albrecht Stephanie Roessler Moritz Löffler Anastasia Lemekhova Arianeb Mehrabi Beat P Müller-Stich Katrin Hoffmann

J Gastrointest Surg 2020 May 6. Epub 2020 May 6.

Department of General-, Visceral- and Transplantation Surgery, University Hospital Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.

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May 2020

NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis.

Authors:
Sarah Luiken Angelika Fraas Matthias Bieg Raisatun Sugiyanto Benjamin Goeppert Stephan Singer Carolin Ploeger Gregor Warsow Jens U Marquardt Carsten Sticht Carolina De La Torre Stefan Pusch Arianeb Mehrabi Norbert Gretz Matthias Schlesner Roland Eils Peter Schirmacher Thomas Longerich Stephanie Roessler

Oncogene 2020 04 13;39(15):3128-3144. Epub 2020 Feb 13.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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April 2020

Genomic Characterization of Cholangiocarcinoma in Primary Sclerosing Cholangitis Reveals Therapeutic Opportunities.

Authors:
Benjamin Goeppert Trine Folseraas Stephanie Roessler Matthias Kloor Anna-Lena Volckmar Volker Endris Ivo Buchhalter Albrecht Stenzinger Krzysztof Grzyb Marit M Grimsrud Barbara Gornicka Erik von Seth Gary M Reynolds Andre Franke Daniel N Gotthardt Arianeb Mehrabi Angela Cheung Joanne Verheij Johanna Arola Heikki Mäkisalo Tor J Eide Sören Weidemann John C Cheville Giuseppe Mazza Gideon M Hirschfield Cyriel Y Ponsioen Annika Bergquist Piotr Milkiewicz Konstantinos N Lazaridis Christoph Schramm Michael P Manns Martti Färkkilä Arndt Vogel Kirsten M Boberg Peter Schirmacher Tom H Karlsen

Hepatology 2020 Oct 19;72(4):1253-1266. Epub 2020 Aug 19.

Norwegian PSC Research Center Department of Transplantation Medicine, Division of Surgery, Inflammatory Medicine and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway.

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October 2020

HER2 gene (ERBB2) amplification is a low-frequency driver with potential predictive value in gallbladder carcinoma.

Authors:
Thomas Albrecht Melina Rausch Stephanie Roessler Veronika Geissler Michael Albrecht Christine Halske Carolin Seifert Marcus Renner Stephan Singer Arianeb Mehrabi Monika Nadja Vogel Anita Pathil-Warth Elena Busch Bruno Köhler Christian Rupp Karl Heinz Weiss Christoph Springfeld Christoph Röcken Peter Schirmacher Benjamin Goeppert

Virchows Arch 2020 Jun 14;476(6):871-880. Epub 2019 Dec 14.

Institute of Pathology, Heidelberg University Hospital, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.

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June 2020

Karyopherin α2-dependent import of E2F1 and TFDP1 maintains protumorigenic stathmin expression in liver cancer.

Authors:
Elisabeth Drucker Kerstin Holzer Stefan Pusch Juliane Winkler Diego F Calvisi Eva Eiteneuer Esther Herpel Benjamin Goeppert Stephanie Roessler Alessandro Ori Peter Schirmacher Kai Breuhahn Stephan Singer

Cell Commun Signal 2019 11 29;17(1):159. Epub 2019 Nov 29.

Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.

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November 2019

Nucleoporin Nup155 is part of the p53 network in liver cancer.

Authors:
Kerstin Holzer Alessandro Ori Amy Cooke Daniel Dauch Elisabeth Drucker Philip Riemenschneider Amparo Andres-Pons Amanda L DiGuilio Marie-Therese Mackmull Jochen Baßler Stephanie Roessler Kai Breuhahn Lars Zender Joseph S Glavy Frank Dombrowski Ed Hurt Peter Schirmacher Martin Beck Stephan Singer

Nat Commun 2019 05 14;10(1):2147. Epub 2019 May 14.

Institute of Pathology, University Hospital Heidelberg, 69120, Heidelberg, Germany.

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May 2019

Low frequency of mismatch repair deficiency in gallbladder cancer.

Authors:
Benjamin Goeppert Stephanie Roessler Marcus Renner Moritz Loeffler Stephan Singer Melina Rausch Thomas Albrecht Arianeb Mehrabi Monika Nadja Vogel Anita Pathil Elena Czink Bruno Köhler Christoph Springfeld Christian Rupp Karl Heinz Weiss Peter Schirmacher Magnus von Knebel Doeberitz Matthias Kloor

Diagn Pathol 2019 May 8;14(1):36. Epub 2019 May 8.

Department of Applied Tumor Biology, Institute of Pathology, University of Heidelberg, Heidelberg, Germany.

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May 2019

Random gene sets in predicting survival of patients with hepatocellular carcinoma.

Authors:
Timo Itzel Rainer Spang Thorsten Maass Stefan Munker Stephanie Roessler Matthias P Ebert Hans J Schlitt Wolfgang Herr Matthias Evert Andreas Teufel

J Mol Med (Berl) 2019 06 17;97(6):879-888. Epub 2019 Apr 17.

Division of Hepatology & Division of Clinical Bioinformatics, Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.

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June 2019