Stephanie Le Gras

Stephanie Le Gras

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Stephanie Le Gras

Stephanie Le Gras

Publications by authors named "Stephanie Le Gras"

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Cell-Type-Specific Gene Expression Profiling in Adult Mouse Brain Reveals Normal and Disease-State Signatures.

Cell Rep 2019 Feb;26(9):2477-2493.e9

Department of Clinical Neurosciences, Laboratory of Neurotherapies and Neuromodulation (LNTM), Lausanne University Hospital, 1011 Lausanne, Switzerland; Neuroscience Research Center, LNTM, Lausanne University Hospital, 1011 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.02.003DOI Listing
February 2019

Genes and Pathways Regulated by Androgens in Human Neural Cells, Potential Candidates for the Male Excess in Autism Spectrum Disorder.

Biol Psychiatry 2018 08 9;84(4):239-252. Epub 2018 Jan 9.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France; Centre National de la Recherche Scientifique, UMR 7104, Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U964, Illkirch, France; Université de Strasbourg, Illkirch, France; Laboratory of Genetic Diagnostics, Hôpitaux Universitaires de Strasbourg, Strasbourg, France. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2018.01.002DOI Listing
August 2018

Combinatorial DNA methylation codes at repetitive elements.

Genome Res 2017 06 27;27(6):934-946. Epub 2017 Mar 27.

Département de Génomique Fonctionnelle et Cancer, Institut de Génétique et Biologie Moléculaire et Cellulaire (IGBMC), UdS, CNRS, INSERM, Equipe labellisée Ligue contre le Cancer, 67404 Illkirch Cedex, France.

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http://dx.doi.org/10.1101/gr.213983.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453327PMC
June 2017

TEAD transcription factors are required for normal primary myoblast differentiation in vitro and muscle regeneration in vivo.

PLoS Genet 2017 02 8;13(2):e1006600. Epub 2017 Feb 8.

Department of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/UNISTRA, Illkirch, France.

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https://dx.plos.org/10.1371/journal.pgen.1006600
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http://dx.doi.org/10.1371/journal.pgen.1006600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323021PMC
February 2017

Altered enhancer transcription underlies Huntington's disease striatal transcriptional signature.

Sci Rep 2017 02 22;7:42875. Epub 2017 Feb 22.

University of Strasbourg, Laboratory of Cognitive and Adaptive Neurosciences (LNCA), 12 rue Goethe, 67000 Strasbourg, France.

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http://dx.doi.org/10.1038/srep42875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320509PMC
February 2017

A targeted next-generation sequencing assay for the molecular diagnosis of genetic disorders with orodental involvement.

J Med Genet 2016 Feb 26;53(2):98-110. Epub 2015 Oct 26.

Centre de Référence des Manifestations Odontologiques des Maladies Rares, Pôle de Médecine et Chirurgie Bucco-dentaires, Hôpitaux Universitaires de Strasbourg (HUS), Strasbourg, France Faculté de Chirurgie Dentaire, Université de Strasbourg, Strasbourg, France Institut de Génétique et de Biologie Moléculaire and Cellulaire-Centre Européen de Recherche en Biologie et en Médecine, CNRS UMR7104, INSERM U964 Université de Strasbourg, Illkirch, France.

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http://dx.doi.org/10.1136/jmedgenet-2015-103302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752661PMC
February 2016

Ikaros mediates gene silencing in T cells through Polycomb repressive complex 2.

Nat Commun 2015 Nov 9;6:8823. Epub 2015 Nov 9.

Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM U964, CNRS UMR 7104, Université de Strasbourg, Equipe Labellisée Ligue Contre le Cancer, 1 rue Laurent Fries, Illkirch 67404, France.

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http://www.nature.com/articles/ncomms9823
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http://dx.doi.org/10.1038/ncomms9823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667618PMC
November 2015

A Brn2-Zic1 axis specifies the neuronal fate of retinoic-acid-treated embryonic stem cells.

J Cell Sci 2015 Jul 19;128(13):2303-18. Epub 2015 May 19.

Department of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/UDS, 1 Rue Laurent Fries, Illkirch, Cédex 67404, France Equipe Labellisée of the Ligue Nationale Contre le Cancer, CNRS/INSERM/UDS, 1 Rue Laurent Fries, Illkirch, Cédex 67404, France

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http://dx.doi.org/10.1242/jcs.168849DOI Listing
July 2015

Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice.

Hum Mol Genet 2015 Jun 17;24(12):3481-96. Epub 2015 Mar 17.

Neurogenetics and Translational Medicine Department, Laboratory of Cognitive and Adaptive Neuroscience, CNRS/University of Strasbourg, UMR 7364, 12 rue Goethe, 67000 Strasbourg, France

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http://dx.doi.org/10.1093/hmg/ddv099DOI Listing
June 2015

TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.

Elife 2014 Sep 10;3:e03613. Epub 2014 Sep 10.

Department of Functional Genomics and Cancer, Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS/INSERM/UDS, Illkirch, France.

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http://dx.doi.org/10.7554/eLife.03613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359380PMC
September 2014

20 ans après: a second mutation in MAOA identified by targeted high-throughput sequencing in a family with altered behavior and cognition.

Eur J Hum Genet 2014 Jun 30;22(6):776-83. Epub 2013 Oct 30.

1] IGBMC, CNRS UMR 7104/INSERM U964/University of Strasbourg, Illkirch Cedex, France [2] Chaire de Génétique Humaine, Collège de France, Paris, France [3] Laboratoire de Diagnostic Génétique, Hôpitaux Universitaires de Strasbourg, France.

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http://dx.doi.org/10.1038/ejhg.2013.243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023218PMC
June 2014

The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells.

Sci Signal 2014 Mar 18;7(317):ra28. Epub 2014 Mar 18.

1Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM U964, CNRS UMR 7104, Université de Strasbourg, 67404 Illkirch, France.

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http://stke.sciencemag.org/cgi/doi/10.1126/scisignal.2004545
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http://dx.doi.org/10.1126/scisignal.2004545DOI Listing
March 2014

Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation.

Genome Res 2013 Oct 26;23(10):1563-79. Epub 2013 Jul 26.

Institut Pasteur, Laboratory of Nuclear Organization and Oncogenesis, Department of Cell Biology and Infection, F-75015 Paris, France;

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http://dx.doi.org/10.1101/gr.154872.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787255PMC
October 2013

Chromatin signatures and retrotransposon profiling in mouse embryos reveal regulation of LINE-1 by RNA.

Nat Struct Mol Biol 2013 Mar 27;20(3):332-8. Epub 2013 Jan 27.

Centre National de la Recherche Scientifique, Institut National de la Santé et de la Recherche Médicale, Université de Strasbourg, Illkirch, France.

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http://dx.doi.org/10.1038/nsmb.2495DOI Listing
March 2013

Trim24-repressed VL30 retrotransposons regulate gene expression by producing noncoding RNA.

Nat Struct Mol Biol 2013 Mar 3;20(3):339-46. Epub 2013 Feb 3.

Department of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.

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http://dx.doi.org/10.1038/nsmb.2496DOI Listing
March 2013

Samaritan myopathy, an ultimately benign congenital myopathy, is caused by a RYR1 mutation.

Acta Neuropathol 2012 Oct 3;124(4):575-81. Epub 2012 Jul 3.

Department of Translational Medecine and Neurogenetics, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.

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http://dx.doi.org/10.1007/s00401-012-1007-3DOI Listing
October 2012

A strategy for direct mapping and identification of mutations by whole-genome sequencing.

Genetics 2010 Sep 6;186(1):427-30. Epub 2010 Jul 6.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Institut National de Santé et de Recherche Médicale (INSERM) U964/Centre National de Recherche Scientifique (CNRS) UMR 1704/Université de Strasbourg, 67404 Illkirch CU Strasbourg, France.

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http://www.genetics.org/content/genetics/186/1/427.full.pdf
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http://www.genetics.org/cgi/doi/10.1534/genetics.110.119230
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http://dx.doi.org/10.1534/genetics.110.119230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940307PMC
September 2010

Bcl11b represses a mature T-cell gene expression program in immature CD4(+)CD8(+) thymocytes.

Eur J Immunol 2010 Aug;40(8):2143-54

Institut de Génétique et de Biologie Moléculaire et Cellulaire, INSERM U964, CNRS UMR7104, Université de Strasbourg, Illkirch, France.

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http://dx.doi.org/10.1002/eji.200940258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942964PMC
August 2010