Stephanie Hoppe

Stephanie Hoppe

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Stephanie Hoppe

Stephanie Hoppe

Publications by authors named "Stephanie Hoppe"

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Brain accumulation of osimertinib and its active metabolite AZ5104 is restricted by ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein).

Pharmacol Res 2019 Aug 5;146:104297. Epub 2019 Jun 5.

Division of Pharmacology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2019.104297DOI Listing
August 2019

P-glycoprotein Limits Ribociclib Brain Exposure and CYP3A4 Restricts Its Oral Bioavailability.

Mol Pharm 2019 Aug 5. Epub 2019 Aug 5.

Division of Pharmacology , The Netherlands Cancer Institute , Amsterdam , The Netherlands.

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http://dx.doi.org/10.1021/acs.molpharmaceut.9b00475DOI Listing
August 2019

Performance Evaluation of MHC Class-I Binding Prediction Tools Based on an Experimentally Validated MHC-Peptide Binding Data Set.

Cancer Immunol Res 2019 May 22;7(5):719-736. Epub 2019 Mar 22.

German Cancer Research Center (DKFZ), Immunotherapy and Immunoprevention, Heidelberg, Germany.

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http://dx.doi.org/10.1158/2326-6066.CIR-18-0584DOI Listing
May 2019

P-Glycoprotein (MDR1/ABCB1) Restricts Brain Penetration of the Bruton's Tyrosine Kinase Inhibitor Ibrutinib, While Cytochrome P450-3A (CYP3A) Limits Its Oral Bioavailability.

Mol Pharm 2018 11 10;15(11):5124-5134. Epub 2018 Oct 10.

Division of Pharmacology , The Netherlands Cancer Institute , 1066 CX Amsterdam , The Netherlands.

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http://dx.doi.org/10.1021/acs.molpharmaceut.8b00702DOI Listing
November 2018

P-glycoprotein (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) affect brain accumulation and intestinal disposition of encorafenib in mice.

Pharmacol Res 2018 03 14;129:414-423. Epub 2017 Nov 14.

The Netherlands Cancer Institute, Division of Pharmacology, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2017.11.006DOI Listing
March 2018

Brain Accumulation of Ponatinib and Its Active Metabolite, N-Desmethyl Ponatinib, Is Limited by P-Glycoprotein (P-GP/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2).

Mol Pharm 2017 10 19;14(10):3258-3268. Epub 2017 Sep 19.

Division of Molecular Oncology, The Netherlands Cancer Institute , Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

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http://pubs.acs.org/doi/10.1021/acs.molpharmaceut.7b00257
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http://dx.doi.org/10.1021/acs.molpharmaceut.7b00257DOI Listing
October 2017

What next? Preferably development of drugs that are no longer transported by the ABCB1 and ABCG2 efflux transporters.

Pharmacol Res 2017 Sep 31;123:144. Epub 2017 May 31.

Division of Molecular Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10436618173058
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http://dx.doi.org/10.1016/j.phrs.2017.05.015DOI Listing
September 2017

Breast cancer resistance protein (BCRP/ABCG2) and P-glycoprotein (P-gp/ABCB1) transport afatinib and restrict its oral availability and brain accumulation.

Pharmacol Res 2017 Jun 10;120:43-50. Epub 2017 Mar 10.

Division of Molecular Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2017.01.035DOI Listing
June 2017

PRognostic factor of Early Death In phase II Trials or the end of 'sufficient life expectancy' as an inclusion criterion? (PREDIT model).

BMC Cancer 2016 10 4;16(1):768. Epub 2016 Oct 4.

Department of Medical Oncology, Institut Bergonié, Comprehensive Cancer Centre Bordeaux, 229 cours de l'Argonne, 33076, Bordeaux, France.

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http://dx.doi.org/10.1186/s12885-016-2819-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050995PMC
October 2016

The impact of Organic Anion-Transporting Polypeptides (OATPs) on disposition and toxicity of antitumor drugs: Insights from knockout and humanized mice.

Drug Resist Updat 2016 07 25;27:72-88. Epub 2016 Jun 25.

The Netherlands Cancer Institute, Division of Molecular Oncology, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.drup.2016.06.005DOI Listing
July 2016

Liquid chromatography-tandem mass spectrometric assay for the tyrosine kinase inhibitor afatinib in mouse plasma using salting-out liquid-liquid extraction.

J Chromatogr B Analyt Technol Biomed Life Sci 2016 Feb 21;1012-1013:118-23. Epub 2016 Jan 21.

Utrecht University, Faculty of Science, Department of Pharmaceutical Sciences, Division of Pharmacoepidemiology & Clinical Pharmacology, Universiteitsweg 99, 3584CG Utrecht, The Netherlands; The Netherlands Cancer Institute, Department of Clinical Pharmacology, Plesmanlaan 121, 1066CX Amsterdam, The Netherlands; Slotervaart Hospital, Department of Pharmacy & Pharmacology, Louwesweg 6, 1066 EC Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2016.01.025DOI Listing
February 2016

Liquid chromatography-tandem mass spectrometric assay for the simultaneous determination of the irreversible BTK inhibitor ibrutinib and its dihydrodiol-metabolite in plasma and its application in mouse pharmacokinetic studies.

J Pharm Biomed Anal 2016 Jan 27;118:123-131. Epub 2015 Oct 27.

Utrecht University, Faculty of Science, Department of Pharmaceutical Sciences, Division of Pharmacoepidemiology & Clinical Pharmacology, Universiteitsweg 99, 3584 CG Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.jpba.2015.10.033DOI Listing
January 2016

Susceptibility to eating disorders among collegiate female student-athletes.

J Athl Train 2014 May-Jun;49(3):406-10. Epub 2014 Apr 24.

Department of Exercise Science and Sport Management, Kennesaw State University, GA.

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http://dx.doi.org/10.4085/1062-6050-49.2.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080598PMC
September 2015

[Oncofertility and breast cancer: Where have we come from, where are we going?].

Bull Cancer 2015 Jun 16;102(6):489-96. Epub 2015 May 16.

Institut de lutte contre le cancer, institut Bergonié, service de chirurgie, Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.bulcan.2015.04.004DOI Listing
June 2015

Functional decline in older patients with cancer receiving first-line chemotherapy.

J Clin Oncol 2013 Nov 23;31(31):3877-82. Epub 2013 Sep 23.

Stéphanie Hoppe, Marianne Fonck, Laurent Hoppenreys, Cécile Mertens, Nadine Houédé, Carine A. Bellera, Anne Floquet, Marie-Noëlle Fabry, Camille Chakiba, Simone Mathoulin-Pélissier, and Pierre Soubeyran, Institut Bergonié; Muriel Rainfray, Jean-Frédéric Blanc, Cécile Mertens, and Alain Ravaud, Centre Hospitalier Universitaire; Muriel Rainfray, Christèle Blanc-Bisson, Alain Ravaud, Simone Mathoulin-Pélissier, and Pierre Soubeyran, University of Bordeaux, Bordeaux; Joël Ceccaldi, Centre Hospitalier, Libourne; Yves Imbert and Luc Vogt, Centre Hospitalier, Agen; Laurent Cany, Clinique Francheville, Périgueux; and Jérôme Dauba, Centre Hospitalier, Mont de Marsan, France.

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http://dx.doi.org/10.1200/JCO.2012.47.7430DOI Listing
November 2013

Targeting cancer cells with the natural compound obtusaquinone.

J Natl Cancer Inst 2013 May 11;105(9):643-53. Epub 2013 Mar 11.

Experimental Therapeutics and Molecular Imaging Laboratory, Neuroscience Center, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1093/jnci/djt037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691947PMC
May 2013