Stephane Hué

Stephane Hué

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Stephane Hué

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Phylogenetic investigation of HCV-4d epidemic in Paris MSM HIV population reveals a still active outbreak and a strong link to the Netherlands.

Clin Microbiol Infect 2020 Feb 5. Epub 2020 Feb 5.

Université de Paris, INSERM UMR 1137 IAME, F-75018, Paris, France; Service de Maladies Infectieuses et Tropicales, AP-HP, Hôpital Bichat-Claude Bernard, F-75018, Paris, France.

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http://dx.doi.org/10.1016/j.cmi.2020.01.034DOI Listing
February 2020

HIV-1 Phylodynamics to Detect and Characterize Active Transmission Clusters in North Carolina.

J Infect Dis 2019 Apr 27. Epub 2019 Apr 27.

Division of Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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https://academic.oup.com/jid/advance-article/doi/10.1093/inf
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http://dx.doi.org/10.1093/infdis/jiz176DOI Listing
April 2019

Caution is needed in interpreting HIV transmission chains by ultradeep sequencing.

AIDS 2019 03;33(4):691-699

Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.

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http://dx.doi.org/10.1097/QAD.0000000000002105DOI Listing
March 2019

Leveraging Phylogenetics to Understand HIV Transmission and Partner Notification Networks.

J Acquir Immune Defic Syndr 2018 08;78(4):367-375

Division of Infectious Diseases, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.

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http://dx.doi.org/10.1097/QAI.0000000000001695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058319PMC
August 2018

Prevalence and Transmission Dynamics of HIV-1 Transmitted Drug Resistance in a Southeastern Cohort.

Open Forum Infect Dis 2018 Aug 20;5(8):ofy178. Epub 2018 Jul 20.

Division of Infectious Diseases, University of North Carolina, Chapel Hill, North Carolina.

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http://dx.doi.org/10.1093/ofid/ofy178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101542PMC
August 2018

Rising prevalence of non-B HIV-1 subtypes in North Carolina and evidence for local onward transmission.

Virus Evol 2017 Jan 24;3(1):vex013. Epub 2017 May 24.

Division of Infectious Diseases, University of North Carolina, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1093/ve/vex013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442504PMC
January 2017

Low risk of a sexually-transmitted Zika virus outbreak.

Lancet Infect Dis 2016 10 19;16(10):1100-1102. Epub 2016 Sep 19.

Department of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.

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http://dx.doi.org/10.1016/S1473-3099(16)30324-3DOI Listing
October 2016

Hepatitis C virus quasispecies and pseudotype analysis from acute infection to chronicity in HIV-1 co-infected individuals.

Virology 2016 May 21;492:213-24. Epub 2016 Mar 21.

Division of Infection & Immunity, Faculty of Medical Sciences, University College London, United Kingdom; Wellcome Trust Africa Centre for Health and Population Sciences, University of KwaZulu, Natal, South Africa.

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http://dx.doi.org/10.1016/j.virol.2016.02.003DOI Listing
May 2016

Positive Selection Analysis of Overlapping Reading Frames Is Invalid.

AIDS Res Hum Retroviruses 2015 Oct 22;31(10):947. Epub 2015 Jul 22.

2 Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine , London, United Kingdom .

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http://dx.doi.org/10.1089/AID.2015.0150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118959PMC
October 2015

HIV Transmission Patterns Among Immigrant Latinos Illuminated by the Integration of Phylogenetic and Migration Data.

AIDS Res Hum Retroviruses 2015 Oct 24;31(10):973-80. Epub 2015 Aug 24.

1 Division of Infectious Diseases, School of Medicine, University of North Carolina , Chapel Hill, North Carolina.

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http://dx.doi.org/10.1089/AID.2015.0089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576933PMC
October 2015

A phylotype-based analysis highlights the role of drug-naive HIV-positive individuals in the transmission of antiretroviral resistance in the UK.

AIDS 2015 Sep;29(15):1917-25

aInstitut de Biologie Computationnelle, LIRMM, UMR5506 CNRS bMIVEGEC, CNRS 5290, IRD 224, Université de Montpellier, Montpellier, France cMRC Clinical Trial Unit at UCL dPublic Health England eChelsea & Westminster Hospital fUniversity College London gLondon School of Hygiene and Tropical Medicine, London, UK.

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http://dx.doi.org/10.1097/QAD.0000000000000768DOI Listing
September 2015

Single Genome Analysis for the Detection of Linked Multiclass Drug Resistance Mutations in HIV-1-Infected Children After Failure of Protease Inhibitor-Based First-Line Therapy.

J Acquir Immune Defic Syndr 2015 Jun;69(2):138-44

*Division of Infection and Immunity, University College London, London United Kingdom; †Perinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; ‡Children's Infectious Diseases Clinical Research Unit, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa; §Medical Research Council Clinical Trials Unit, University College London, London, United Kingdom; ||HJF-DAIDS, a Division of the Henry M Jackson Foundation for the Advancement of Military Medicine Inc, Contractor, NIAID, NIH, Department of Health and Human Services, Bethesda, MD; ¶Anova Health Institute, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa; and #Africa Centre for Health and Population Studies, University of KwaZulu Natal.

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http://dx.doi.org/10.1097/QAI.0000000000000568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679142PMC
June 2015

G2/M cell cycle arrest correlates with primate lentiviral Vpr interaction with the SLX4 complex.

J Virol 2015 Jan 15;89(1):230-40. Epub 2014 Oct 15.

Department of Infectious Diseases, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom

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http://dx.doi.org/10.1128/JVI.02307-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301105PMC
January 2015

Phylogenetic analyses reveal HIV-1 infections between men misclassified as heterosexual transmissions.

AIDS 2014 Aug;28(13):1967-75

aDepartment of Infection, University College London bHIV and STI Department, Public Health England, London cSchool of Biological Sciences, University of Edinburgh, Edinburgh dInstitute of Biodiversity, University of Glasgow, Glasgow eMedical Research Council Clinical Trial Unit fHIV and Sexual Health Clinic, Chelsea and Westminster Hospital, London, UK.

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http://dx.doi.org/10.1097/QAD.0000000000000383DOI Listing
August 2014

New insights into an X-traordinary viral protein.

Front Microbiol 2014 8;5:126. Epub 2014 Apr 8.

Department of Infectious Diseases, King's College London London, UK.

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http://dx.doi.org/10.3389/fmicb.2014.00126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986551PMC
June 2014

Preservation of tetherin and CD4 counter-activities in circulating Vpu alleles despite extensive sequence variation within HIV-1 infected individuals.

PLoS Pathog 2014 Jan 23;10(1):e1003895. Epub 2014 Jan 23.

Department of Infectious Disease, King's College School of Medicine, Guy's Hospital, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.ppat.1003895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900648PMC
January 2014

Hepatitis B virus candidate subgenotype I1 varies in distribution throughout Guangxi, China and may have originated in Long An county, Guangxi.

J Med Virol 2013 May;85(5):799-807

Department of Public Health, Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China.

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http://dx.doi.org/10.1002/jmv.23533DOI Listing
May 2013

Phylogenetic and demographic characterization of HIV-1 transmission in Madrid, Spain.

Infect Genet Evol 2013 Mar 2;14:232-9. Epub 2013 Jan 2.

HIV-1 Molecular Epidemiology Laboratory, Department of Microbiology, Hospital Ramón y Cajal-IRYCIS and CIBERESP, Ctra. Colmenar Viejo, Km 9.100, 28034 Madrid, Spain.

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http://dx.doi.org/10.1016/j.meegid.2012.12.006DOI Listing
March 2013

Phylogenetic insights into regional HIV transmission.

AIDS 2012 Sep;26(14):1813-22

Division of Infectious Diseases, University of North Carolina, Chapel Hill, North Carolina 27599-7030, USA.

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http://dx.doi.org/10.1097/QAD.0b013e3283573244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566771PMC
September 2012

HIV type 1 in a rural coastal town in Kenya shows multiple introductions with many subtypes and much recombination.

AIDS Res Hum Retroviruses 2012 Feb 19;28(2):220-4. Epub 2011 Jul 19.

Centre for Medical Molecular Virology, University College, London, United Kingdom.

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http://dx.doi.org/10.1089/aid.2011.0048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275924PMC
February 2012

In vivo emergence of HIV-1 highly sensitive to neutralizing antibodies.

PLoS One 2011 24;6(8):e23961. Epub 2011 Aug 24.

MRC/UCL Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0023961PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161086PMC
February 2012

HIV-1 Group P is unable to antagonize human tetherin by Vpu, Env or Nef.

Retrovirology 2011 Dec 15;8:103. Epub 2011 Dec 15.

Institute of Molecular Virology, Ulm University Medical Center, 89069, Ulm, Germany.

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http://dx.doi.org/10.1186/1742-4690-8-103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285029PMC
December 2011

Evolution of a species-specific determinant within human CRM1 that regulates the post-transcriptional phases of HIV-1 replication.

PLoS Pathog 2011 Nov 17;7(11):e1002395. Epub 2011 Nov 17.

Department of Infectious Diseases, King's College London School of Medicine, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.ppat.1002395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219727PMC
November 2011

Phylogenetic analysis of murine leukemia virus sequences from longitudinally sampled chronic fatigue syndrome patients suggests PCR contamination rather than viral evolution.

J Virol 2011 Oct 17;85(20):10909-13. Epub 2011 Aug 17.

Department of Zoology, University of Oxford, South Parks Road, Oxford OX13PS, United Kingdom.

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http://dx.doi.org/10.1128/JVI.00827-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187511PMC
October 2011

Hare TRIM5α restricts divergent retroviruses and exhibits significant sequence variation from closely related lagomorpha TRIM5 genes.

J Virol 2010 Dec 22;84(23):12463-8. Epub 2010 Sep 22.

MRC Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, Windeyer Building, London, United Kingdom.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.01514-10
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http://dx.doi.org/10.1128/JVI.01514-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976397PMC
December 2010

Disease-associated XMRV sequences are consistent with laboratory contamination.

Retrovirology 2010 Dec 20;7(1):111. Epub 2010 Dec 20.

MRC Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, 46 Cleveland St, London W1T 4JF, UK.

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http://dx.doi.org/10.1186/1742-4690-7-111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018392PMC
December 2010

Novel subtype C human immunodeficiency virus type 1 envelopes cloned directly from plasma: coreceptor usage and neutralization phenotypes.

J Gen Virol 2010 Sep 19;91(Pt 9):2374-80. Epub 2010 May 19.

MRC/UCL Centre for Medical Molecular Virology, University College London, London W1T 4JF, UK.

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http://dx.doi.org/10.1099/vir.0.022228-0DOI Listing
September 2010

Conformational adaptation of Asian macaque TRIMCyp directs lineage specific antiviral activity.

PLoS Pathog 2010 Aug 19;6(8):e1001062. Epub 2010 Aug 19.

University College London Medical Research Council Centre for Medical Molecular Virology, London, UK.

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http://dx.doi.org/10.1371/journal.ppat.1001062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924388PMC
August 2010

The calibrated population resistance tool: standardized genotypic estimation of transmitted HIV-1 drug resistance.

Bioinformatics 2009 May 20;25(9):1197-8. Epub 2009 Mar 20.

Division of Infectious Diseases, Department of Medicine, Stanford University, Stanford, CA, USA.

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http://dx.doi.org/10.1093/bioinformatics/btp134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672634PMC
May 2009

Mutation of a single residue renders human tetherin resistant to HIV-1 Vpu-mediated depletion.

PLoS Pathog 2009 May 22;5(5):e1000443. Epub 2009 May 22.

Medical Research Council Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, London, United Kingdom.

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http://dx.plos.org/10.1371/journal.ppat.1000443
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http://dx.doi.org/10.1371/journal.ppat.1000443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678251PMC
May 2009

Demonstration of sustained drug-resistant human immunodeficiency virus type 1 lineages circulating among treatment-naïve individuals.

J Virol 2009 Mar 21;83(6):2645-54. Epub 2009 Jan 21.

UCL/MRC Centre for Medical Molecular Virology, University College London, Windeyer Building, 46 Cleveland Street, London W1T 4JF, United Kingdom.

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http://dx.doi.org/10.1128/JVI.01556-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648277PMC
March 2009

An active TRIM5 protein in rabbits indicates a common antiviral ancestor for mammalian TRIM5 proteins.

J Virol 2007 Nov 29;81(21):11713-21. Epub 2007 Aug 29.

MRC Centre for Medical Molecular Virology, Department of Infection, Royal Free and University College Medical School, University College London, 46 Cleveland Street, London, United Kingdom.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.01468-07
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http://dx.doi.org/10.1128/JVI.01468-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168759PMC
November 2007

Investigating signs of recent evolution in the pool of proviral HIV type 1 DNA during years of successful HAART.

AIDS Res Hum Retroviruses 2007 Jan;23(1):107-15

Department of Infectious Diseases, Rigshospitalet, Technical University of Denmark, Copenhagen, Denmark.

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http://dx.doi.org/10.1089/aid.2006.0089DOI Listing
January 2007

Sexual transmission of single human immunodeficiency virus type 1 virions encoding highly polymorphic multisite cytotoxic T-lymphocyte escape variants.

J Virol 2005 Nov;79(22):13953-62

The Peter Medawar Building for Pathogen Research and The James Martin 21st Century School, Nuffield Department of Clinical Medicine, University of Oxford, South Parks Road, Oxford OX1 3SY, United Kingdom

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http://dx.doi.org/10.1128/JVI.79.22.13953-13962.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1280182PMC
November 2005

Genetic analysis reveals the complex structure of HIV-1 transmission within defined risk groups.

Proc Natl Acad Sci U S A 2005 Mar 14;102(12):4425-9. Epub 2005 Mar 14.

Centre for Virology, Division of Infection and Immunity, University College London, 46 Cleveland Street, London W1T 4JF, UK.

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http://dx.doi.org/10.1073/pnas.0407534102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC555492PMC
March 2005

Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance.

J Infect Dis 2004 Apr 12;189(7):1232-8. Epub 2004 Mar 12.

Unidade de Genetica e Biologia Molecular, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Brazil.

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http://dx.doi.org/10.1086/382483DOI Listing
April 2004

HIV-1 pol gene variation is sufficient for reconstruction of transmissions in the era of antiretroviral therapy.

AIDS 2004 Mar;18(5):719-28

Division of Immunity and Infection, University of Birmingham and Regional Health Protection Agency, Birmingham Heartlands Hospital, London, UK.

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http://dx.doi.org/10.1097/00002030-200403260-00002DOI Listing
March 2004

Poxvirus genomes: a phylogenetic analysis.

J Gen Virol 2004 Jan;85(Pt 1):105-17

Department of Virology, Faculty of Medicine, Imperial College London, St Mary's Campus, Norfolk Place, London W2 1PG, UK.

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http://jgv.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/vir.0.19565-0DOI Listing
January 2004

Identification of a transmission chain of HIV type 1 containing drug resistance-associated mutations.

AIDS Res Hum Retroviruses 2003 May;19(5):353-61

Public Health Laboratory Service Antiviral Susceptibility Reference Unit, Division of Immunity and Infection, University of Birmingham, Birmingham B9 5SS, UK.

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http://dx.doi.org/10.1089/088922203765551700DOI Listing
May 2003

Minimal variation in T-20 binding domain of different HIV-1 subtypes from antiretroviral-naive and -experienced patients.

AIDS 2002 Aug;16(12):1684-6

PHLS Antiviral Susceptibility Unit, Division of Immunity and Infection, University of Birmingham Medical School, Birmingham, UK.

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http://dx.doi.org/10.1097/00002030-200208160-00016DOI Listing
August 2002

Anaphylactoid reactions to iodinated contrast media.

Acad Radiol 2002 Aug;9 Suppl 2:S431-2

Laboratory of Medical Physics, Service de Biophysique Médicale, CHRU de Caen, France.

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http://dx.doi.org/10.1016/s1076-6332(03)80253-2DOI Listing
August 2002