Publications by authors named "Stephane Flibotte"

66Publications

Coordinate Regulation of Ribosome and tRNA Biogenesis Controls Hypoxic Injury and Translation.

Authors:
Omar A Itani Xuefei Zhong Xiaoting Tang Barbara A Scott Jun Yi Yan Stephane Flibotte Yiting Lim Andrew C Hsieh James E Bruce Marc Van Gilst C Michael Crowder

Curr Biol 2021 Jan 5;31(1):128-137.e5. Epub 2020 Nov 5.

Department of Anesthesiology and Pain Medicine, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195-6540, USA; Mitochondria and Metabolism Center, University of Washington, 850 Republican Street, Seattle, WA 98105, USA; Department of Genome Sciences, University of Washington, 3720 15th Ave NE, Seattle, WA 98105, USA. Electronic address:

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January 2021

A low affinity -regulatory BMP response element restricts target gene activation to subsets of Drosophila neurons.

Authors:
Anthony Je Berndt Katerina M Othonos Tianshun Lian Stephane Flibotte Mo Miao Shamsuddin A Bhuiyan Raymond Y Cho Justin S Fong Seo Am Hur Paul Pavlidis Douglas W Allan

Elife 2020 10 30;9. Epub 2020 Oct 30.

Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, Canada.

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October 2020

Loss of function of transcription factor EB remodels lipid metabolism and cell death pathways in the cardiomyocyte.

Authors:
Purvi C Trivedi Jordan J Bartlett Angella Mercer Logan Slade Marc Surette Andrea Ballabio Stephane Flibotte Bahira Hussein Brian Rodrigues Petra C Kienesberger Thomas Pulinilkunnil

Biochim Biophys Acta Mol Basis Dis 2020 10 8;1866(10):165832. Epub 2020 May 8.

Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, NS, Canada; Dalhousie Medicine New Brunswick, E2L 4L5 Saint John, NB, Canada. Electronic address:

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October 2020

A Multimodal Genotoxic Anticancer Drug Characterized by Pharmacogenetic Analysis in .

Authors:
Frank B Ye Akil Hamza Tejomayee Singh Stephane Flibotte Philip Hieter Nigel J O'Neil

Genetics 2020 Jul 15;215(3):609-621. Epub 2020 May 15.

Michael Smith Laboratories, University of British Columbia, Vancouver, V6T 1Z4, Canada

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July 2020

Requirement for translocon-associated protein (TRAP) α in insulin biogenesis.

Authors:
Xin Li Omar A Itani Leena Haataja Kathleen J Dumas Jing Yang Jeeyeon Cha Stephane Flibotte Hung-Jen Shih Colin E Delaney Jialu Xu Ling Qi Peter Arvan Ming Liu Patrick J Hu

Sci Adv 2019 12 4;5(12):eaax0292. Epub 2019 Dec 4.

Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.

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December 2019

Diabetes Mellitus Severity and a Switch From Using Lipoprotein Lipase to Adipose-Derived Fatty Acid Results in a Cardiac Metabolic Signature That Embraces Cell Death.

Authors:
Karanjit Puri Nathaniel Lal Rui Shang Sanjoy Ghosh Stephane Flibotte Roger Dyer Bahira Hussein Brian Rodrigues

J Am Heart Assoc 2019 11 31;8(21):e014022. Epub 2019 Oct 31.

Faculty of Pharmaceutical Sciences University of British Columbia Vancouver BC Canada.

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November 2019

A Receptor Tyrosine Kinase Plays Separate Roles in Sensory Integration and Associative Learning in .

Authors:
Glenn S Wolfe Vivian W Tong Emily Povse Daniel M Merritt Gregory W Stegeman Stephane Flibotte Derek van der Kooy

eNeuro 2019 Jul/Aug;6(4). Epub 2019 Aug 13.

Institute of Medical Science, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

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March 2020

Heparanase protects the heart against chemical or ischemia/reperfusion injury.

Authors:
Fulong Wang Thomas Pulinilkunnil Stephane Flibotte Corey Nislow Israel Vlodavsky Bahira Hussein Brian Rodrigues

J Mol Cell Cardiol 2019 06 17;131:29-40. Epub 2019 Apr 17.

Faculty of Pharmaceutical Sciences, University of British Columbia, 2405 Wesbrook Mall, Vancouver, BC V6T 1Z3, Canada. Electronic address:

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June 2019

The meiotic phosphatase GSP-2/PP1 promotes germline immortality and small RNA-mediated genome silencing.

Authors:
Katherine Kretovich Billmyre Anna-Lisa Doebley Maya Spichal Bree Heestand Tony Belicard Aya Sato-Carlton Stephane Flibotte Matt Simon Megan Gnazzo Ahna Skop Donald Moerman Peter Mark Carlton Peter Sarkies Shawn Ahmed

PLoS Genet 2019 03 28;15(3):e1008004. Epub 2019 Mar 28.

Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States of America.

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March 2019

MicroRNA Biomarkers in Cerebrospinal Fluid and Serum Reflect Injury Severity in Human Acute Traumatic Spinal Cord Injury.

Authors:
Seth Tigchelaar Rishab Gupta Casey P Shannon Femke Streijger Sunita Sinha Stephane Flibotte Michael A Rizzuto John Street Scott Paquette Tamir Ailon Raphaele Charest-Morin Nicolas Dea Charles Fisher Marcel F Dvorak Sanjay Dhall Jean-Marc Mac-Thiong Stefan Parent Christopher Bailey Sean Christie Kendall Van Keuren-Jensen Corey Nislow Brian K Kwon

J Neurotrauma 2019 08 14;36(15):2358-2371. Epub 2019 May 14.

1International Collaboration on Repair Discoveries (ICORD), University of British Columbia, Vancouver, British Columbia, Canada.

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August 2019

Retrograde BMP signaling activates neuronal gene expression through widespread deployment of a conserved BMP-responsive cis-regulatory activation element.

Authors:
Robin Vuilleumier Tianshun Lian Stephane Flibotte Zaynah N Khan Alisa Fuchs George Pyrowolakis Douglas W Allan

Nucleic Acids Res 2019 01;47(2):679-699

Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, British Columbia, Canada.

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January 2019

CRISPR/Cas9 Methodology for the Generation of Knockout Deletions in .

Authors:
Vinci Au Erica Li-Leger Greta Raymant Stephane Flibotte George Chen Kiana Martin Lisa Fernando Claudia Doell Federico I Rosell Su Wang Mark L Edgley Ann E Rougvie Harald Hutter Donald G Moerman

G3 (Bethesda) 2019 01 9;9(1):135-144. Epub 2019 Jan 9.

Department of Zoology and Michael Smith Laboratories

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January 2019

DIP-2 suppresses ectopic neurite sprouting and axonal regeneration in mature neurons.

Authors:
Nathaniel Noblett Zilu Wu Zhao Hua Ding Seungmee Park Tony Roenspies Stephane Flibotte Andrew D Chisholm Yishi Jin Antonio Colavita

J Cell Biol 2019 01 5;218(1):125-133. Epub 2018 Nov 5.

Neuroscience Program, Ottawa Hospital Research Institute, Ottawa, Canada

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January 2019

Mutational and transcriptional landscape of spontaneous gene duplications and deletions in .

Authors:
Anke Konrad Stephane Flibotte Jon Taylor Robert H Waterston Donald G Moerman Ulfar Bergthorsson Vaishali Katju

Proc Natl Acad Sci U S A 2018 07 25;115(28):7386-7391. Epub 2018 Jun 25.

Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX 77845;

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July 2018

A Strategy To Isolate Modifiers of Lethal Mutations: Investigating the Endoderm Specifying Ability of the Intestinal Differentiation GATA Factor ELT-2.

Authors:
Tobias Wiesenfahrt Jingjie Duanmu Frances Snider Don Moerman Vinci Au Erica Li-Leger Stephane Flibotte Dylan M Parker Craig J Marshall Erin Osborne Nishimura Paul E Mains James D McGhee

G3 (Bethesda) 2018 05 4;8(5):1425-1437. Epub 2018 May 4.

Department of Biochemistry and Molecular Biology, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada T2N 4N1

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May 2018

The Molecular Chaperone HSP90 Promotes Notch Signaling in the Germline of .

Authors:
James L Lissemore Elyse Connors Ying Liu Li Qiao Bing Yang Mark L Edgley Stephane Flibotte Jon Taylor Vinci Au Donald G Moerman Eleanor M Maine

G3 (Bethesda) 2018 05 4;8(5):1535-1544. Epub 2018 May 4.

Department of Biology, Syracuse University, NY 13244.

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May 2018

Ribosomal Protein S12e Has a Distinct Function in Cell Competition.

Authors:
Abhijit Kale Zhejun Ji Marianthi Kiparaki Jorge Blanco Gerard Rimesso Stephane Flibotte Nicholas E Baker

Dev Cell 2018 01 8;44(1):42-55.e4. Epub 2018 Jan 8.

Department of Genetics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA; Department of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA. Electronic address:

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January 2018

Reducing insulin via conditional partial gene ablation in adults reverses diet-induced weight gain.

Authors:
Melissa M Page Søs Skovsø Haoning Cen Amy P Chiu Derek A Dionne Daria F Hutchinson Gareth E Lim Marta Szabat Stephane Flibotte Sunita Sinha Corey Nislow Brian Rodrigues James D Johnson

FASEB J 2018 03 3;32(3):1196-1206. Epub 2018 Jan 3.

Department of Cellular and Physiological Sciences, Diabetes Research Group, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada.

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March 2018

Reduced Circulating Insulin Enhances Insulin Sensitivity in Old Mice and Extends Lifespan.

Authors:
Nicole M Templeman Stephane Flibotte Jenny H L Chik Sunita Sinha Gareth E Lim Leonard J Foster Corey Nislow James D Johnson

Cell Rep 2017 07;20(2):451-463

Department of Cellular and Physiological Sciences, Diabetes Research Group, Life Sciences Institute, University of British Columbia, Vancouver, BC V6T 1Z3, Canada. Electronic address:

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July 2017

Recurrent background mutations in WHI2 impair proteostasis and degradation of misfolded cytosolic proteins in Saccharomyces cerevisiae.

Authors:
Sophie A Comyn Stéphane Flibotte Thibault Mayor

Sci Rep 2017 06 23;7(1):4183. Epub 2017 Jun 23.

Department of Biochemistry and Molecular Biology, Michael Smith Laboratories, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada.

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June 2017

Comparative functional genomic screens of three yeast deletion collections reveal unexpected effects of genotype in response to diverse stress.

Authors:
Erica Acton Amy Huei-Yi Lee Pei Jun Zhao Stephane Flibotte Mauricio Neira Sunita Sinha Jennifer Chiang Patrick Flaherty Corey Nislow Guri Giaever

Open Biol 2017 06;7(6)

Department of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada

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June 2017

Insight into the Recent Genome Duplication of the Halophilic Yeast : Combining an Improved Genome with Gene Expression and Chromatin Structure.

Authors:
Sunita Sinha Stephane Flibotte Mauricio Neira Sean Formby Ana Plemenitaš Nina Gunde Cimerman Metka Lenassi Cene Gostinčar Jason E Stajich Corey Nislow

G3 (Bethesda) 2017 07 5;7(7):2015-2022. Epub 2017 Jul 5.

Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver V6T 1Z3, Canada

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July 2017

Serum MicroRNAs Reflect Injury Severity in a Large Animal Model of Thoracic Spinal Cord Injury.

Authors:
Seth Tigchelaar Femke Streijger Sunita Sinha Stephane Flibotte Neda Manouchehri Kitty So Katelyn Shortt Elena Okon Michael A Rizzuto Ivana Malenica Amanda Courtright-Lim Andrew Eisen Kendall Van Keuren-Jensen Corey Nislow Brian K Kwon

Sci Rep 2017 05 3;7(1):1376. Epub 2017 May 3.

International Collaboration on Repair Discoveries (ICORD), University of British Columbia, Vancouver, British Columbia, Canada.

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May 2017

Phenotypic diversity and genotypic flexibility of during long-term chronic infection of cystic fibrosis lungs.

Authors:
Amy Huei-Yi Lee Stephane Flibotte Sunita Sinha Adrianna Paiero Rachel L Ehrlich Sergey Balashov Garth D Ehrlich James E A Zlosnik Joshua Chang Mell Corey Nislow

Genome Res 2017 04 21;27(4):650-662. Epub 2017 Mar 21.

Department of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.

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April 2017

Genome-Wide Screen Reveals Mutants of Are Methotrexate-Resistant.

Authors:
Lai H Wong Stephane Flibotte Sunita Sinha Jennifer Chiang Guri Giaever Corey Nislow

G3 (Bethesda) 2017 04 3;7(4):1251-1257. Epub 2017 Apr 3.

Department of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada

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April 2017

Heparanase Overexpression Induces Glucagon Resistance and Protects Animals From Chemically Induced Diabetes.

Authors:
Dahai Zhang Fulong Wang Nathaniel Lal Amy Pei-Ling Chiu Andrea Wan Jocelyn Jia Denise Bierende Stephane Flibotte Sunita Sinha Ali Asadi Xiaoke Hu Farnaz Taghizadeh Thomas Pulinilkunnil Corey Nislow Israel Vlodavsky James D Johnson Timothy J Kieffer Bahira Hussein Brian Rodrigues

Diabetes 2017 Jan 7;66(1):45-57. Epub 2016 Oct 7.

Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, British Columbia, Canada

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January 2017

Using C. elegans Forward and Reverse Genetics to Identify New Compounds with Anthelmintic Activity.

Authors:
Mark D Mathew Neal D Mathew Angela Miller Mike Simpson Vinci Au Stephanie Garland Marie Gestin Mark L Edgley Stephane Flibotte Aruna Balgi Jennifer Chiang Guri Giaever Pamela Dean Audrey Tung Michel Roberge Calvin Roskelley Tom Forge Corey Nislow Donald Moerman

PLoS Negl Trop Dis 2016 Oct 18;10(10):e0005058. Epub 2016 Oct 18.

Department of Zoology and Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.

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October 2016

Accelerating Gene Discovery by Phenotyping Whole-Genome Sequenced Multi-mutation Strains and Using the Sequence Kernel Association Test (SKAT).

Authors:
Tiffany A Timbers Stephanie J Garland Swetha Mohan Stephane Flibotte Mark Edgley Quintin Muncaster Vinci Au Erica Li-Leger Federico I Rosell Jerry Cai Suzanne Rademakers Gert Jansen Donald G Moerman Michel R Leroux

PLoS Genet 2016 08 10;12(8):e1006235. Epub 2016 Aug 10.

Department of Molecular Biology and Biochemistry and Centre for Cell Biology, Development, and Disease, Simon Fraser University, Burnaby, British Columbia, Canada.

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August 2016

Novel small molecules potentiate premature termination codon readthrough by aminoglycosides.

Authors:
Alireza Baradaran-Heravi Aruna D Balgi Carla Zimmerman Kunho Choi Fahimeh S Shidmoossavee Jason S Tan Célia Bergeaud Alexandra Krause Stéphane Flibotte Yoko Shimizu Hilary J Anderson Vincent Mouly Eric Jan Tom Pfeifer James B Jaquith Michel Roberge

Nucleic Acids Res 2016 08 12;44(14):6583-98. Epub 2016 Jul 12.

Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada

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August 2016

The SWI/SNF chromatin remodeling complex exerts both negative and positive control over LET-23/EGFR-dependent vulval induction in Caenorhabditis elegans.

Authors:
Stephane Flibotte Bo Ram Kim Emily Van de Laar Louise Brown Nadeem Moghal

Dev Biol 2016 07 17;415(1):46-63. Epub 2016 May 17.

Princess Margaret Cancer Centre/University Health Network, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada M5G 1L7. Electronic address:

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July 2016

UBR-5, a Conserved HECT-Type E3 Ubiquitin Ligase, Negatively Regulates Notch-Type Signaling in Caenorhabditis elegans.

Authors:
Komal Safdar Anniya Gu Xia Xu Vinci Au Jon Taylor Stephane Flibotte Donald G Moerman Eleanor M Maine

G3 (Bethesda) 2016 07 7;6(7):2125-34. Epub 2016 Jul 7.

Department of Biology, Syracuse University, New York 13244

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July 2016

N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Reveals an Intronic Residue Critical for Caenorhabditis elegans 3' Splice Site Function in Vivo.

Authors:
Omar A Itani Stephane Flibotte Kathleen J Dumas Chunfang Guo Thomas Blumenthal Patrick J Hu

G3 (Bethesda) 2016 06 1;6(6):1751-6. Epub 2016 Jun 1.

Institute of Gerontology and Departments of Internal Medicine and Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan 48109

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June 2016

Rapid Increase in frequency of gene copy-number variants during experimental evolution in Caenorhabditis elegans.

Authors:
James C Farslow Kendra J Lipinski Lucille B Packard Mark L Edgley Jon Taylor Stephane Flibotte Donald G Moerman Vaishali Katju Ulfar Bergthorsson

BMC Genomics 2015 Dec 9;16:1044. Epub 2015 Dec 9.

Department of Biology, University of New Mexico, Albuquerque, NM, 87131, USA.

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December 2015

Chromoanasynthetic Genomic Rearrangement Identified in a N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Screen in Caenorhabditis elegans.

Authors:
Omar A Itani Stephane Flibotte Kathleen J Dumas Donald G Moerman Patrick J Hu

G3 (Bethesda) 2015 Dec 1;6(2):351-6. Epub 2015 Dec 1.

Institute of Gerontology, University of Michigan Medical School, Ann Arbor, Michigan 48109 Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109 Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan 48109

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December 2015

Spectrum of variations in dog-1/FANCJ and mdf-1/MAD1 defective Caenorhabditis elegans strains after long-term propagation.

Authors:
Maja Tarailo-Graovac Tammy Wong Zhaozhao Qin Stephane Flibotte Jon Taylor Donald G Moerman Ann M Rose Nansheng Chen

BMC Genomics 2015 Mar 18;16:210. Epub 2015 Mar 18.

Department of Molecular Biology and Biochemistry, Simon Fraser University, V5A 1S6, Burnaby, BC, Canada.

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March 2015

Cyclin B3 and dynein heavy chain cooperate to increase fitness in the absence of mdf-1/MAD1 in Caenorhabditis elegans.

Authors:
Maja Tarailo-Graovac Tammy Wong Zhaozhao Qin Stephane Flibotte Jon Taylor Donald G Moerman Ann M Rose Nansheng Chen

Cell Cycle 2014 ;13(19):3089-199

a Department of Molecular Biology and Biochemistry ; Simon Fraser University ; Burnaby , BC Canada.

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August 2015

Random and targeted transgene insertion in Caenorhabditis elegans using a modified Mos1 transposon.

Authors:
Christian Frøkjær-Jensen M Wayne Davis Mihail Sarov Jon Taylor Stephane Flibotte Matthew LaBella Andrei Pozniakovsky Donald G Moerman Erik M Jorgensen

Nat Methods 2014 May 16;11(5):529-34. Epub 2014 Mar 16.

1] Howard Hughes Medical Institute, University of Utah, Salt Lake City, Utah, USA. [2] Department of Biology, University of Utah, Salt Lake City, Utah, USA.

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May 2014

A network of HSPG core proteins and HS modifying enzymes regulates netrin-dependent guidance of D-type motor neurons in Caenorhabditis elegans.

Authors:
Stephan Gysi Christa Rhiner Stephane Flibotte Donald G Moerman Michael O Hengartner

PLoS One 2013 16;8(9):e74908. Epub 2013 Sep 16.

Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland ; Neuroscience Center Zurich, University of Zurich, Zurich, Switzerland.

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May 2014

The million mutation project: a new approach to genetics in Caenorhabditis elegans.

Authors:
Owen Thompson Mark Edgley Pnina Strasbourger Stephane Flibotte Brent Ewing Ryan Adair Vinci Au Iasha Chaudhry Lisa Fernando Harald Hutter Armelle Kieffer Joanne Lau Norris Lee Angela Miller Greta Raymant Bin Shen Jay Shendure Jon Taylor Emily H Turner LaDeana W Hillier Donald G Moerman Robert H Waterston

Genome Res 2013 Oct 25;23(10):1749-62. Epub 2013 Jun 25.

Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA;

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October 2013

Unexpected role for dosage compensation in the control of dauer arrest, insulin-like signaling, and FoxO transcription factor activity in Caenorhabditis elegans.

Authors:
Kathleen J Dumas Colin E Delaney Stephane Flibotte Donald G Moerman Gyorgyi Csankovszki Patrick J Hu

Genetics 2013 Jul 3;194(3):619-29. Epub 2013 Jun 3.

Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, USA.

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July 2013

Chromosome movements promoted by the mitochondrial protein SPD-3 are required for homology search during Caenorhabditis elegans meiosis.

Authors:
Leticia Labrador Consuelo Barroso James Lightfoot Thomas Müller-Reichert Stephane Flibotte Jon Taylor Donald G Moerman Anne M Villeneuve Enrique Martinez-Perez

PLoS Genet 2013 May 9;9(5):e1003497. Epub 2013 May 9.

MRC Clinical Sciences Centre, Imperial College Faculty of Medicine, London, United Kingdom.

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May 2013

Genetic control of vulval development in Caenorhabditis briggsae.

Authors:
Devika Sharanya Bavithra Thillainathan Sujatha Marri Nagagireesh Bojanala Jon Taylor Stephane Flibotte Donald G Moerman Robert H Waterston Bhagwati P Gupta

G3 (Bethesda) 2012 Dec 1;2(12):1625-41. Epub 2012 Dec 1.

Department of Biology, McMaster University, Hamilton, Ontario L8S 4K1, Canada.

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December 2012

DNA synthesis generates terminal duplications that seal end-to-end chromosome fusions.

Authors:
Mia Rochelle Lowden Stephane Flibotte Donald G Moerman Shawn Ahmed

Science 2011 Apr;332(6028):468-71

Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.

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April 2011

Widespread, focal copy number variations (CNV) and whole chromosome aneuploidies in Trypanosoma cruzi strains revealed by array comparative genomic hybridization.

Authors:
Todd A Minning D Brent Weatherly Stephane Flibotte Rick L Tarleton

BMC Genomics 2011 Mar 7;12:139. Epub 2011 Mar 7.

Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia 30602, USA.

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March 2011

C. elegans ADAMTS ADT-2 regulates body size by modulating TGFβ signaling and cuticle collagen organization.

Authors:
Thilini Fernando Stephane Flibotte Sheng Xiong Jianghua Yin Edlira Yzeiraj Donald G Moerman Alicia Meléndez Cathy Savage-Dunn

Dev Biol 2011 Apr 21;352(1):92-103. Epub 2011 Jan 21.

Department of Biology, Queens College, and The Graduate School and University Center, City University of New York, Flushing, NY 11367, USA.

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April 2011

Whole-genome profiling of mutagenesis in Caenorhabditis elegans.

Authors:
Stephane Flibotte Mark L Edgley Iasha Chaudhry Jon Taylor Sarah E Neil Aleksandra Rogula Rick Zapf Martin Hirst Yaron Butterfield Steven J Jones Marco A Marra Robert J Barstead Donald G Moerman

Genetics 2010 Jun 3;185(2):431-41. Epub 2010 May 3.

Department of Zoology, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada.

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June 2010

Genomic sequence of a mutant strain of Caenorhabditis elegans with an altered recombination pattern.

Authors:
Ann M Rose Nigel J O'Neil Mikhail Bilenky Yaron S Butterfield Nawar Malhis Stephane Flibotte Martin R Jones Marco Marra David L Baillie Steven J M Jones

BMC Genomics 2010 Feb 23;11:131. Epub 2010 Feb 23.

Department of Medical Genetics, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada.

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February 2010

Copy number variation in the genomes of twelve natural isolates of Caenorhabditis elegans.

Authors:
Jason S Maydan Adam Lorch Mark L Edgley Stephane Flibotte Donald G Moerman

BMC Genomics 2010 Jan 25;11:62. Epub 2010 Jan 25.

Department of Zoology, University of British Columbia, British Columbia, Canada.

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January 2010

New tools for investigating the comparative biology of Caenorhabditis briggsae and C. elegans.

Authors:
Zhongying Zhao Stephane Flibotte John I Murray Daniel Blick Thomas J Boyle Bhagwati Gupta Donald G Moerman Robert H Waterston

Genetics 2010 Mar 14;184(3):853-63. Epub 2009 Dec 14.

Department of Genome Sciences, University of Washington, Seattle, Washington 98195-5065, USA.

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March 2010

Detection of pathogenic copy number variants in children with idiopathic intellectual disability using 500 K SNP array genomic hybridization.

Authors:
Jm Friedman Shelin Adam Laura Arbour Linlea Armstrong Agnes Baross Patricia Birch Cornelius Boerkoel Susanna Chan David Chai Allen D Delaney Stephane Flibotte William T Gibson Sylvie Langlois Emmanuelle Lemyre H Irene Li Patrick MacLeod Joan Mathers Jacques L Michaud Barbara C McGillivray Millan S Patel Hong Qian Guy A Rouleau Margot I Van Allen Siu-Li Yong Farah R Zahir Patrice Eydoux Marco A Marra

BMC Genomics 2009 Nov 16;10:526. Epub 2009 Nov 16.

Department of Medical Genetics, University of British Columbia, Vancouver, Canada.

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November 2009

Cis-regulatory mutations in the Caenorhabditis elegans homeobox gene locus cog-1 affect neuronal development.

Authors:
M Maggie O'Meara Henry Bigelow Stephane Flibotte John F Etchberger Donald G Moerman Oliver Hobert

Genetics 2009 Apr 2;181(4):1679-86. Epub 2009 Feb 2.

Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biophysics, Columbia University Medical Center, New York, NY 10032, USA.

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April 2009

De Novo identification of single nucleotide mutations in Caenorhabditis elegans using array comparative genomic hybridization.

Authors:
Jason S Maydan H Mark Okada Stephane Flibotte Mark L Edgley Donald G Moerman

Genetics 2009 Apr 2;181(4):1673-7. Epub 2009 Feb 2.

Department of Zoology, University of British Columbia V6T 1Z4, Vancouver, British Columbia, Canada.

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April 2009

Rapid high resolution single nucleotide polymorphism-comparative genome hybridization mapping in Caenorhabditis elegans.

Authors:
Stephane Flibotte Mark L Edgley Jason Maydan Jon Taylor Rick Zapf Robert Waterston Donald G Moerman

Genetics 2009 Jan 28;181(1):33-7. Epub 2008 Oct 28.

Department of Zoology, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada.

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January 2009

Experimental analysis of oligonucleotide microarray design criteria to detect deletions by comparative genomic hybridization.

Authors:
Stephane Flibotte Donald G Moerman

BMC Genomics 2008 Oct 21;9:497. Epub 2008 Oct 21.

Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC, Canada.

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October 2008

Transcription of foreign DNA in Escherichia coli.

Authors:
René L Warren John D Freeman Roger C Levesque Duane E Smailus Stephane Flibotte Robert A Holt

Genome Res 2008 Nov 13;18(11):1798-805. Epub 2008 Aug 13.

BC Cancer Agency, Canada's Michael Smith Genome Sciences Centre, Vancouver, British Columbia V5Z 4S6, Canada.

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November 2008

ALEXA: a microarray design platform for alternative expression analysis.

Authors:
Malachi Griffith Michelle J Tang Obi L Griffith Ryan D Morin Susanna Y Chan Jennifer K Asano Thomas Zeng Stephane Flibotte Adrian Ally Agnes Baross Martin Hirst Steven J M Jones Gregg B Morin Isabella T Tai Marco A Marra

Nat Methods 2008 Feb;5(2):118

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February 2008

Oligonucleotide Array Comparative Genomic Hybridization (oaCGH) based characterization of genetic deficiencies as an aid to gene mapping in Caenorhabditis elegans.

Authors:
Martin R Jones Jason S Maydan Stephane Flibotte Donald G Moerman David L Baillie

BMC Genomics 2007 Nov 7;8:402. Epub 2007 Nov 7.

Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby BC V35 1S6 Canada.

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November 2007

Assessment of algorithms for high throughput detection of genomic copy number variation in oligonucleotide microarray data.

Authors:
Agnes Baross Allen D Delaney H Irene Li Tarun Nayar Stephane Flibotte Hong Qian Susanna Y Chan Jennifer Asano Adrian Ally Manqiu Cao Patricia Birch Mabel Brown-John Nicole Fernandes Anne Go Giulia Kennedy Sylvie Langlois Patrice Eydoux J M Friedman Marco A Marra

BMC Bioinformatics 2007 Oct 2;8:368. Epub 2007 Oct 2.

Genome Sciences Centre, BC Cancer Agency, British Columbia Cancer Agency, Suite 100, 570 West 7th Avenue, Vancouver, BC, V5Z 4S6, Canada.

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October 2007

Rebuilding microbial genomes.

Authors:
Robert A Holt Rene Warren Stephane Flibotte Perseus I Missirlis Duane E Smailus

Bioessays 2007 Jun;29(6):580-90

Canada's Michael Smith Genome Sciences Centre, Vancouver, British Columbia, Canada.

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June 2007

Efficient high-resolution deletion discovery in Caenorhabditis elegans by array comparative genomic hybridization.

Authors:
Jason S Maydan Stephane Flibotte Mark L Edgley Joanne Lau Rebecca R Selzer Todd A Richmond Nathan J Pofahl James H Thomas Donald G Moerman

Genome Res 2007 Mar 31;17(3):337-47. Epub 2007 Jan 31.

Department of Zoology, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada.

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March 2007

Oligonucleotide microarray analysis of genomic imbalance in children with mental retardation.

Authors:
J M Friedman Agnes Baross Allen D Delaney Adrian Ally Laura Arbour Linlea Armstrong Jennifer Asano Dione K Bailey Sarah Barber Patricia Birch Mabel Brown-John Manqiu Cao Susanna Chan David L Charest Noushin Farnoud Nicole Fernandes Stephane Flibotte Anne Go William T Gibson Robert A Holt Steven J M Jones Giulia C Kennedy Martin Krzywinski Sylvie Langlois Haiyan I Li Barbara C McGillivray Tarun Nayar Trevor J Pugh Evica Rajcan-Separovic Jacqueline E Schein Angelique Schnerch Asim Siddiqui Margot I Van Allen Gary Wilson Siu-Li Yong Farah Zahir Patrice Eydoux Marco A Marra

Am J Hum Genet 2006 Sep 25;79(3):500-13. Epub 2006 Jul 25.

Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.

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September 2006

DNA copy-number analysis in bipolar disorder and schizophrenia reveals aberrations in genes involved in glutamate signaling.

Authors:
Gary M Wilson Stephane Flibotte Vikramjit Chopra Brianna L Melnyk William G Honer Robert A Holt

Hum Mol Genet 2006 Mar 24;15(5):743-9. Epub 2006 Jan 24.

Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Suite 100, 570 West 7th Avenue, Vancouver, BC, Canada V5Z 4S6.

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March 2006

Identification by full-coverage array CGH of human DNA copy number increases relative to chimpanzee and gorilla.

Authors:
Gary M Wilson Stephane Flibotte Perseus I Missirlis Marco A Marra Steven Jones Kevin Thornton Andrew G Clark Robert A Holt

Genome Res 2006 Feb 19;16(2):173-81. Epub 2005 Dec 19.

Canada's Michael Smith Genome Sciences Centre, Vancouver, BC, Canada V5Z 4S6.

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February 2006

Analytical and preanalytical biases in serum proteomic pattern analysis for breast cancer diagnosis.

Authors:
Aly Karsan Bernhard J Eigl Stephane Flibotte Karen Gelmon Philip Switzer Patricia Hassell Dorothy Harrison Jennifer Law Malcolm Hayes Moira Stillwell Zhen Xiao Thomas P Conrads Timothy Veenstra

Clin Chem 2005 Aug 10;51(8):1525-8. Epub 2005 Jun 10.

Department of Pathology and Laboratory Medicine, British Columbia Cancer Agency, Vancouver, BC, Canada.

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August 2005

Identification of serum amyloid A as a biomarker to distinguish prostate cancer patients with bone lesions.

Authors:
Lyly Le Kim Chi Scott Tyldesley Stephane Flibotte Deborah L Diamond Michael A Kuzyk Marianne D Sadar

Clin Chem 2005 Apr 3;51(4):695-707. Epub 2005 Feb 3.

British Columbia Cancer Agency, Vancouver, British Columbia, Canada.

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April 2005

Automated ordering of fingerprinted clones.

Authors:
Stephane Flibotte Readman Chiu Chris Fjell Martin Krzywinski Jacqueline E Schein Heesun Shin Marco A Marra

Bioinformatics 2004 May 10;20(8):1264-71. Epub 2004 Feb 10.

Genome Sciences Centre, British Columbia Cancer Research Centre, Vancouver, BC Canada, V5Z 4E6.

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May 2004