Stephane Angers

Stephane Angers

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Stephane Angers

Publications by authors named "Stephane Angers"

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IPO11 mediates βcatenin nuclear import in a subset of colorectal cancers.

J Cell Biol 2020 Feb;219(2)

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1083/jcb.201903017DOI Listing
February 2020

Functional Enhancers Shape Extrachromosomal Oncogene Amplifications.

Cell 2019 Nov 21;179(6):1330-1341.e13. Epub 2019 Nov 21.

Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Case Comprehensive Cancer Center, Cleveland, OH 44106, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.10.039DOI Listing
November 2019

High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting.

Nat Biomed Eng 2019 Oct 23;3(10):796-805. Epub 2019 Sep 23.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/s41551-019-0454-8DOI Listing
October 2019

Identifying chemogenetic interactions from CRISPR screens with drugZ.

Genome Med 2019 08 22;11(1):52. Epub 2019 Aug 22.

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1186/s13073-019-0665-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706933PMC
August 2019

Agonist-induced desensitisation of β -adrenoceptors: Where, when, and how?

Br J Pharmacol 2019 Jul 7;176(14):2539-2558. Epub 2019 Apr 7.

Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany.

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http://dx.doi.org/10.1111/bph.14633DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592865PMC
July 2019

Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma.

Dev Cell 2019 01 13;48(2):167-183.e5. Epub 2018 Dec 13.

Program in Developmental & Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada; Joint Institute of Genetics and Genomic Medicine, Zhejiang University and University of Toronto, Toronto, ON, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15345807183093
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http://dx.doi.org/10.1016/j.devcel.2018.11.015DOI Listing
January 2019

Three-Dimensional Nanostructured Architectures Enable Efficient Neural Differentiation of Mesenchymal Stem Cells via Mechanotransduction.

Nano Lett 2018 11 18;18(11):7188-7193. Epub 2018 Oct 18.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy , University of Toronto , Toronto , M5S 3M2 , Canada.

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http://pubs.acs.org/doi/10.1021/acs.nanolett.8b03313
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http://dx.doi.org/10.1021/acs.nanolett.8b03313DOI Listing
November 2018

Wnt signaling in development and tissue homeostasis.

Development 2018 06 8;145(11). Epub 2018 Jun 8.

University of Toronto, 144 College Street, Toronto, ON M5S 3M2, Canada

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http://dx.doi.org/10.1242/dev.146589DOI Listing
June 2018

High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.

Mol Cell 2018 02 25;69(3):517-532.e11. Epub 2018 Jan 25.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.12.020DOI Listing
February 2018

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

Cell Stem Cell 2017 08 14;21(2):209-224.e7. Epub 2017 Jul 14.

Developmental and Stem Cell Biology Program and Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada; Division of Neurosurgery, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2017.06.004DOI Listing
August 2017

Identification of Novel Smoothened Ligands Using Structure-Based Docking.

PLoS One 2016 4;11(8):e0160365. Epub 2016 Aug 4.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160365PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973902PMC
July 2017

Separating the Anti-Inflammatory and Diabetogenic Effects of Glucocorticoids Through LXRβ Antagonism.

Endocrinology 2017 04;158(4):1034-1047

Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario M5S 3M2, Canada.

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http://dx.doi.org/10.1210/en.2017-00094DOI Listing
April 2017

Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay.

J Cell Sci 2016 10;129(20):3892-3902

MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, Cambridge CB2 0QH, UK

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http://dx.doi.org/10.1242/jcs.195685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087658PMC
October 2016

Role of Spinophilin in Group I Metabotropic Glutamate Receptor Endocytosis, Signaling, and Synaptic Plasticity.

J Biol Chem 2016 08 29;291(34):17602-15. Epub 2016 Jun 29.

the Department of Anatomy and Cell Biology, University of Western Ontario, London, Ontario N6A 3K7, Canada, and

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http://dx.doi.org/10.1074/jbc.M116.722355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016157PMC
August 2016

Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins.

Proc Natl Acad Sci U S A 2016 08 2;113(33):9304-9. Epub 2016 Aug 2.

Department of Experimental Biology, Faculty of Science, Masaryk University, 61 137 Brno, Czech Republic; Institute of Biophysics, Academy of Sciences of Czech Republic, 61 200 Brno, Czech Republic;

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http://dx.doi.org/10.1073/pnas.1608783113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995965PMC
August 2016

PRICKLE1 Contributes to Cancer Cell Dissemination through Its Interaction with mTORC2.

Dev Cell 2016 May 12;37(4):311-325. Epub 2016 May 12.

Inserm, U1068, CRCM, Cell Polarity, Cell Signalling and Cancer "Equipe labellisée Ligue Contre le Cancer", Marseille 13009, France; Institut Paoli-Calmettes, Marseille 13009, France; Aix-Marseille Université, UM 105, Marseille 13284, France; CNRS, UMR7258, CRCM, Marseille 13009, France. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2016.04.011DOI Listing
May 2016

Visualization of a short-range Wnt gradient in the intestinal stem-cell niche.

Nature 2016 Feb 10;530(7590):340-3. Epub 2016 Feb 10.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht, 3584CT Utrecht, the Netherlands.

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http://dx.doi.org/10.1038/nature16937DOI Listing
February 2016

SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the Gαi-LGN-NuMA Ternary Complex.

Dev Cell 2016 Jan;36(1):50-62

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, ON M5S 3M2, Canada; Department of Biochemistry, University of Toronto, ON M5S 1A8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2015.12.016DOI Listing
January 2016

The Pseudomonas syringae type III effector HopF2 suppresses Arabidopsis stomatal immunity.

PLoS One 2014 11;9(12):e114921. Epub 2014 Dec 11.

Department of Cell & Systems Biology, University of Toronto, 25 Willcocks St., Toronto, Ontario, Canada; Centre for the Analysis of Genome Evolution & Function, University of Toronto, Toronto, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0114921PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263708PMC
December 2015

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

Cell 2015 Dec 25;163(6):1515-26. Epub 2015 Nov 25.

Donnelly Centre, 160 College Street, Toronto, ON M5S3E1, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S1A1, Canada; Canadian Institute for Advanced Research, Toronto, ON M5G1Z8, Canada. Electronic address:

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http://www.cell.com/cell/pdf/S0092-8674(15)01495-6.pdf
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http://www.cell.com/cms/attachment/2042476803/2055463631/mmc
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http://linkinghub.elsevier.com/retrieve/pii/S009286741501495
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http://dx.doi.org/10.1016/j.cell.2015.11.015DOI Listing
December 2015

A Par-1-Par-3-Centrosome Cell Polarity Pathway and Its Tuning for Isotropic Cell Adhesion.

Curr Biol 2015 Oct 8;25(20):2701-8. Epub 2015 Oct 8.

Department of Cell & Systems Biology, University of Toronto, 25 Harbord Street, Toronto, ON M5S 3G5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2015.08.063DOI Listing
October 2015

BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.

Mol Cell Proteomics 2015 Jul 21;14(7):1781-95. Epub 2015 Apr 21.

From the ‡Princess Margaret Cancer Centre, University Health Network; ‡‡Department of Medical Biophysics, University of Toronto, Toronto, ON Canada

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http://www.mcponline.org/content/14/7/1781.full.pdf
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http://www.mcponline.org/lookup/doi/10.1074/mcp.M114.045658
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http://dx.doi.org/10.1074/mcp.M114.045658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587326PMC
July 2015

Tandem affinity purification to identify cytosolic and nuclear gβγ-interacting proteins.

Methods Mol Biol 2015 ;1234:161-84

Department of Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1007/978-1-4939-1755-6_14DOI Listing
June 2015

Ca(2+)/calmodulin-dependent protein kinase II interacts with group I metabotropic glutamate and facilitates receptor endocytosis and ERK1/2 signaling: role of β-amyloid.

Mol Brain 2015 Mar 26;8:21. Epub 2015 Mar 26.

J. Allyn Taylor Centre for Cell Biology, Robarts Research Institute, and the Department of Physiology and Pharmacology, University of Western Ontario, 100 Perth Dr. London, Ontario, N6A 5K8, Canada.

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http://dx.doi.org/10.1186/s13041-015-0111-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378271PMC
March 2015

New insights in the regulation of Rab GTPases by G protein-coupled receptors.

Small GTPases 2014 9;5:e29039. Epub 2014 May 9.

Service de Rhumatologie; Département de Médecine; Faculté de Médecine et des Sciences de la Santé; and the Institut de Pharmacologie de Sherbrooke; Université de Sherbrooke; and the Centre de Recherche du Centre Hospitalier de l'Université de Sherbrooke, Sherbrooke, QC Canada.

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http://dx.doi.org/10.4161/sgtp.29039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205129PMC
February 2015

Stepping stone: a cytohesin adaptor for membrane cytoskeleton restraint in the syncytial Drosophila embryo.

Mol Biol Cell 2015 Feb 24;26(4):711-25. Epub 2014 Dec 24.

Department of Cell and Systems Biology, University of Toronto, Toronto, ON M5S 3G5, Canada

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http://dx.doi.org/10.1091/mbc.E14-11-1554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325841PMC
February 2015

Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development.

Dev Biol 2015 Jan 13;397(2):191-202. Epub 2014 Nov 13.

Program in Developmental & Stem Cell Biology, The Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada M5S 1A8. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2014.10.023DOI Listing
January 2015

The PPFIA1-PP2A protein complex promotes trafficking of Kif7 to the ciliary tip and Hedgehog signaling.

Sci Signal 2014 Dec 9;7(355):ra117. Epub 2014 Dec 9.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario M5S 3M2, Canada. Department of Biochemistry, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

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http://dx.doi.org/10.1126/scisignal.2005608DOI Listing
December 2014

Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic β cells.

Mol Cell Proteomics 2014 Nov 20;13(11):3049-62. Epub 2014 Jul 20.

From the ‡Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Canada, M5S 1A8; §Division of Advanced Diagnosis, Toronto General Research Institute, Toronto, Canada, M5G 1C7;

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http://dx.doi.org/10.1074/mcp.M114.040196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223491PMC
November 2014

Ubiquitylation and activation of a Rab GTPase is promoted by a β₂AR-HACE1 complex.

J Cell Sci 2014 Jan 4;127(Pt 1):111-23. Epub 2013 Nov 4.

Service de Rhumatologie, Département de Médecine, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, the Centre de Recherche Clinique Étienne-Le Bel, Sherbrooke, QC J1H 5N4, Canada.

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http://dx.doi.org/10.1242/jcs.132944DOI Listing
January 2014

Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability.

Mol Endocrinol 2013 Aug 24;27(8):1245-66. Epub 2013 Jun 24.

Service de Rhumatologie Département de Médecine, Université de Sherbrooke, the Institut de Pharmacologie de Sherbrooke, and the Centre de Recherche Clinique Etienne-Lebel, Sherbrooke, Québec J1H 5N4, Canada.

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http://dx.doi.org/10.1210/me.2013-1091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427950PMC
August 2013

A novel assay for measurement of membrane-protein surface expression using a β-lactamase.

Traffic 2013 Jul 5;14(7):778-84. Epub 2013 May 5.

Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/tra.12073DOI Listing
July 2013

Emerging non-canonical functions for heterotrimeric G proteins in cellular signaling.

J Recept Signal Transduct Res 2013 Jun;33(3):177-83

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.3109/10799893.2013.795972DOI Listing
June 2013

Inhibition of tankyrases induces Axin stabilization and blocks Wnt signalling in breast cancer cells.

PLoS One 2012 7;7(11):e48670. Epub 2012 Nov 7.

Department of Biochemistry, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0048670PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492487PMC
May 2013

Ptk7 promotes non-canonical Wnt/PCP-mediated morphogenesis and inhibits Wnt/β-catenin-dependent cell fate decisions during vertebrate development.

Development 2013 Apr;140(8):1807-18

Program in Developmental & Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.

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http://dx.doi.org/10.1242/dev.090183DOI Listing
April 2013

Radil controls neutrophil adhesion and motility through β2-integrin activation.

Mol Biol Cell 2012 Dec 24;23(24):4751-65. Epub 2012 Oct 24.

Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

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http://www.molbiolcell.org/doi/10.1091/mbc.e12-05-0408
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http://dx.doi.org/10.1091/mbc.E12-05-0408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521683PMC
December 2012

KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression.

J Cell Biol 2012 Dec 3;199(6):951-67. Epub 2012 Dec 3.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 1A1, Canada.

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http://dx.doi.org/10.1083/jcb.201206051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518219PMC
December 2012

Gli proteins in development and disease.

Annu Rev Cell Dev Biol 2011 21;27:513-37. Epub 2011 Jul 21.

Program in Developmental and Stem Cell Biology, Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada.

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http://dx.doi.org/10.1146/annurev-cellbio-092910-154048DOI Listing
February 2012

Mink1 regulates β-catenin-independent Wnt signaling via Prickle phosphorylation.

Mol Cell Biol 2012 Jan 28;32(1):173-85. Epub 2011 Oct 28.

Department of Pharmaceutical Sciences, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1128/MCB.06320-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255712PMC
January 2012

Tandem affinity purification and identification of heterotrimeric g protein-associated proteins.

Methods Mol Biol 2011 ;756:357-70

Department of Pharmaceutical Sciences & Biochemistry, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/978-1-61779-160-4_22DOI Listing
December 2011

Calcium-sensing receptor modulates cell adhesion and migration via integrins.

J Biol Chem 2011 Nov 3;286(47):40922-33. Epub 2011 Oct 3.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario M5S 3M2, Canada.

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http://dx.doi.org/10.1074/jbc.M111.265454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220485PMC
November 2011

The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signaling.

Mol Cell Biol 2011 May 7;31(10):2053-65. Epub 2011 Mar 7.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, M5S 3M2 Ontario, Canada.

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http://mcb.asm.org/cgi/doi/10.1128/MCB.01094-10
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http://dx.doi.org/10.1128/MCB.01094-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133363PMC
May 2011

G protein betagamma subunits regulate cell adhesion through Rap1a and its effector Radil.

J Biol Chem 2010 Feb 4;285(9):6538-51. Epub 2010 Jan 4.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario M5S 3M2, Canada.

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http://dx.doi.org/10.1074/jbc.M109.069948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825450PMC
February 2010

Proximal events in Wnt signal transduction.

Nat Rev Mol Cell Biol 2009 Jul;10(7):468-77

Leslie Dan Faculty of Pharmacy and the Department of Biochemistry, University of Toronto, Ontario, M5S 3M2, Canada.

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http://dx.doi.org/10.1038/nrm2717DOI Listing
July 2009

Glutamate transporter coupling to Na,K-ATPase.

J Neurosci 2009 Jun;29(25):8143-55

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario M5S 3M2, Canada.

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http://www.jneurosci.org/content/29/25/8143.full.pdf
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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.1081-09.2
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http://dx.doi.org/10.1523/JNEUROSCI.1081-09.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6666056PMC
June 2009

Modulation of the beta-catenin signaling pathway by the dishevelled-associated protein Hipk1.

PLoS One 2009 2;4(2):e4310. Epub 2009 Feb 2.

Department of Pharmacology, Howard Hughes Medical Institute, University of Washington School of Medicine, Seattle, Washington, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0004310PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629544PMC
April 2009

Proteomic analyses of protein complexes in the Wnt pathway.

Authors:
Stephane Angers

Methods Mol Biol 2008 ;468:223-30

Leslie Dan Faculty of Pharmacy, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1007/978-1-59745-249-6_17DOI Listing
January 2009

New regulators of Wnt/beta-catenin signaling revealed by integrative molecular screening.

Sci Signal 2008 Nov 11;1(45):ra12. Epub 2008 Nov 11.

Howard Hughes Medical Institute, Department of Pharmacology, Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, Box 357370, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1126/scisignal.2000037DOI Listing
November 2008

[The tumor suppressor gene WTX, mutated in Wilms tumours, is a member of the beta-catenin destruction complex].

Authors:
Stéphane Angers

Med Sci (Paris) 2007 Nov;23(11):1025-7

Chaire de Recherche du Canada en Architecture Fonctionnelle des Complexes de Signalisation, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, M5S 3M2 Canada.

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http://dx.doi.org/10.1051/medsci/200723111025DOI Listing
November 2007

Recovery of oligomers and cooperativity when monomers of the M2 muscarinic cholinergic receptor are reconstituted into phospholipid vesicles.

Biochemistry 2007 Jul 7;46(26):7907-27. Epub 2007 Jun 7.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada M5S 3M2.

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http://phm.utoronto.ca/angers/Biochemistry%202007%20Recovery
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http://pubs.acs.org/doi/abs/10.1021/bi6026105
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http://dx.doi.org/10.1021/bi6026105DOI Listing
July 2007

Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling.

Science 2007 May;316(5827):1043-6

Howard Hughes Medical Institute, University of Washington School of Medicine, Box 357370, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1126/science/1141515DOI Listing
May 2007

Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery.

Nature 2006 Oct;443(7111):590-3

Howard Hughes Medical Institute, University of Washington, School of Medicine, Box 357280, Seattle, Washington 98195, USA.

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http://dx.doi.org/10.1038/nature05175DOI Listing
October 2006

The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation.

Nat Cell Biol 2006 Apr 19;8(4):348-57. Epub 2006 Mar 19.

Howard Hughes Medical Institute, University of Washington School of Medicine, Box 357370, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1038/ncb1381DOI Listing
April 2006

An aplysia dopamine1-like receptor: molecular and functional characterization.

J Neurochem 2006 Jan 29;96(2):414-27. Epub 2005 Nov 29.

Département de biochimie, Université de Montréal, Montréal, Québec, Canada.

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http://dx.doi.org/10.1111/j.1471-4159.2005.03561.xDOI Listing
January 2006

Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting.

J Biol Chem 2004 Aug 20;279(32):33390-7. Epub 2004 May 20.

Department of Biochemistry and Groupe de Recherche sur le Système Nerveux Autonome, Université de Montréal, Montréal, Quebec H3C 3J7, Canada.

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http://dx.doi.org/10.1074/jbc.M403363200DOI Listing
August 2004

Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer.

J Biol Chem 2002 Nov 19;277(47):44925-31. Epub 2002 Sep 19.

Département de Biochimie and Groupe de Recherche sur le Système Nerveux Autonome, Université de Montréal, Montréal, Quebec H3C 3J7, Canada.

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http://dx.doi.org/10.1074/jbc.M205767200DOI Listing
November 2002

Constitutive agonist-independent CCR5 oligomerization and antibody-mediated clustering occurring at physiological levels of receptors.

J Biol Chem 2002 Sep 27;277(38):34666-73. Epub 2002 Jun 27.

Department of Cell Biology, Cochin Institute, INSERM U-567, CNRS UMR-8104 and University René-Descartes, Paris 75014, France.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M202386200
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http://dx.doi.org/10.1074/jbc.M202386200DOI Listing
September 2002

Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer.

J Biol Chem 2002 Jun 8;277(24):21522-8. Epub 2002 Apr 8.

Department of Cell Biology, Institut Cochin, INSERM U 567, CNRS UMR 8104, 22 rue Méchain, 75014 Paris, France.

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http://dx.doi.org/10.1074/jbc.M200729200DOI Listing
June 2002

Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function.

Annu Rev Pharmacol Toxicol 2002 ;42:409-35

Department of Biochemistry and Groupe de Recherche sur le Système Nerveux Autonome, Université de Montréal, Montréal, H3C 3J7, Canada.

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http://dx.doi.org/10.1146/annurev.pharmtox.42.091701.082314DOI Listing
April 2002