Stephan Weidinger

Stephan Weidinger

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Stephan Weidinger

Stephan Weidinger

Publications by authors named "Stephan Weidinger"

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Transient epidermal barrier deficiency and lowered allergic threshold in filaggrin-hornerin (FlgHrnr ) double-deficient mice.

Allergy 2019 Mar 4. Epub 2019 Mar 4.

Department of Dermatology, Venereology, and Allergology, University Medical Center, Georg August University, Göttingen, Germany.

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http://dx.doi.org/10.1111/all.13756DOI Listing
March 2019

Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Nat Genet 2018 09;50(9):1343

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41588-018-0197-6DOI Listing
September 2018

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Nat Genet 2018 08 16;50(8):1072-1080. Epub 2018 Jul 16.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41588-018-0157-1DOI Listing
August 2018

Atopic dermatitis.

Nat Rev Dis Primers 2018 06 21;4(1). Epub 2018 Jun 21.

Paediatric Dermatology, Our Lady's Children's Hospital Crumlin, Dublin, Ireland.

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http://www.nature.com/articles/s41572-018-0001-z
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http://dx.doi.org/10.1038/s41572-018-0001-zDOI Listing
June 2018

Epidermal lipid composition, barrier integrity, and eczematous inflammation are associated with skin microbiome configuration.

J Allergy Clin Immunol 2018 May 5;141(5):1668-1676.e16. Epub 2018 Feb 5.

Department of Dermatology and Allergy, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.01.019DOI Listing
May 2018

Humidity-regulated CLCA2 protects the epidermis from hyperosmotic stress.

Sci Transl Med 2018 May;10(440)

Institute of Molecular Health Sciences, Department of Biology, ETH Zurich, 8093 Zurich, Switzerland.

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http://dx.doi.org/10.1126/scitranslmed.aao4650DOI Listing
May 2018

The serine protease inhibitor of Kazal-type 7 (SPINK7) is expressed in human skin.

Arch Dermatol Res 2017 Nov 29;309(9):767-771. Epub 2017 Aug 29.

Department of Dermatology, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Schittenhelmstr. 7, 24105, Kiel, Germany.

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http://dx.doi.org/10.1007/s00403-017-1773-9DOI Listing
November 2017

Looking beyond Placebo-Controlled Trials.

J Invest Dermatol 2017 06 28;137(6):1366-1367. Epub 2017 Feb 28.

Department of Dermatology, Venereology and Allergy, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.

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http://dx.doi.org/10.1016/j.jid.2017.02.965DOI Listing
June 2017

Regression of melanoma metastases and multiple non-melanoma skin cancers in xeroderma pigmentosum by the PD1-antibody pembrolizumab.

Eur J Cancer 2017 05 31;77:84-87. Epub 2017 Mar 31.

Department of Dermatology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.

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http://dx.doi.org/10.1016/j.ejca.2017.02.026DOI Listing
May 2017

Sézary Syndrome and Atopic Dermatitis: Comparison of Immunological Aspects and Targets.

Biomed Res Int 2016 17;2016:9717530. Epub 2016 May 17.

Department of Dermatology, Christian-Albrechts-University Kiel, Kiel, Germany.

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http://dx.doi.org/10.1155/2016/9717530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886049PMC
January 2017

Research Waste in Atopic Eczema Trials-Just the Tip of the Iceberg.

J Invest Dermatol 2016 10;136(10):1930-1933

Department of Dermatology, Venereology and Allergy, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.

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http://dx.doi.org/10.1016/j.jid.2016.06.614DOI Listing
October 2016

Genome-wide association study of serum coenzyme Q10 levels identifies susceptibility loci linked to neuronal diseases.

Hum Mol Genet 2016 07 5;25(13):2881-2891. Epub 2016 May 5.

Division of Molecular Prevention, Institute of Human Nutrition and Food Science, Christian-Albrechts-University of Kiel, Heinrich-Hecht-Platz 10, 24118 Kiel, Germany.

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http://dx.doi.org/10.1093/hmg/ddw134DOI Listing
July 2016

Atopic dermatitis.

Lancet 2016 Mar 13;387(10023):1109-1122. Epub 2015 Sep 13.

Department of Dermatology and Allergy, University Hospital Bonn, Bonn, Germany.

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http://dx.doi.org/10.1016/S0140-6736(15)00149-XDOI Listing
March 2016

Targeting IgE in Severe Atopic Dermatitis with a Combination of Immunoadsorption and Omalizumab.

Acta Derm Venereol 2016 Jan;96(1):72-6

Department of Dermatology and Allergy, Technische Universität München (TUM), Biedersteiner Str. 29, DE-80802 Munich, Germany.

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http://dx.doi.org/10.2340/00015555-2165DOI Listing
January 2016

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.

Authors:
Lavinia Paternoster Marie Standl Johannes Waage Hansjörg Baurecht Melanie Hotze David P Strachan John A Curtin Klaus Bønnelykke Chao Tian Atsushi Takahashi Jorge Esparza-Gordillo Alexessander Couto Alves Jacob P Thyssen Herman T den Dekker Manuel A Ferreira Elisabeth Altmaier Patrick Ma Sleiman Feng Li Xiao Juan R Gonzalez Ingo Marenholz Birgit Kalb Maria Pino Yanes Cheng-Jian Xu Lisbeth Carstensen Maria M Groen-Blokhuis Cristina Venturini Craig E Pennell Sheila J Barton Albert M Levin Ivan Curjuric Mariona Bustamante Eskil Kreiner-Møller Gabrielle A Lockett Jonas Bacelis Supinda Bunyavanich Rachel A Myers Anja Matanovic Ashish Kumar Joyce Y Tung Tomomitsu Hirota Michiaki Kubo Wendy L McArdle A J Henderson John P Kemp Jie Zheng George Davey Smith Franz Rüschendorf Anja Bauerfeind Min Ae Lee-Kirsch Andreas Arnold Georg Homuth Carsten O Schmidt Elisabeth Mangold Sven Cichon Thomas Keil Elke Rodríguez Annette Peters Andre Franke Wolfgang Lieb Natalija Novak Regina Fölster-Holst Momoko Horikoshi Juha Pekkanen Sylvain Sebert Lise L Husemoen Niels Grarup Johan C de Jongste Fernando Rivadeneira Albert Hofman Vincent Wv Jaddoe Suzanne Gma Pasmans Niels J Elbert André G Uitterlinden Guy B Marks Philip J Thompson Melanie C Matheson Colin F Robertson Janina S Ried Jin Li Xian Bo Zuo Xiao Dong Zheng Xian Yong Yin Liang Dan Sun Maeve A McAleer Grainne M O'Regan Caoimhe Mr Fahy Linda E Campbell Milan Macek Michael Kurek Donglei Hu Celeste Eng Dirkje S Postma Bjarke Feenstra Frank Geller Jouke Jan Hottenga Christel M Middeldorp Pirro Hysi Veronique Bataille Tim Spector Carla Mt Tiesler Elisabeth Thiering Badri Pahukasahasram James J Yang Medea Imboden Scott Huntsman Natàlia Vilor-Tejedor Caroline L Relton Ronny Myhre Wenche Nystad Adnan Custovic Scott T Weiss Deborah A Meyers Cilla Söderhäll Erik Melén Carole Ober Benjamin A Raby Angela Simpson Bo Jacobsson John W Holloway Hans Bisgaard Jordi Sunyer Nicole M Probst Hensch L Keoki Williams Keith M Godfrey Carol A Wang Dorret I Boomsma Mads Melbye Gerard H Koppelman Deborah Jarvis Wh Irwin McLean Alan D Irvine Xue Jun Zhang Hakon Hakonarson Christian Gieger Esteban G Burchard Nicholas G Martin Liesbeth Duijts Allan Linneberg Marjo-Riitta Jarvelin Markus M Noethen Susanne Lau Norbert Hübner Young-Ae Lee Mayumi Tamari David A Hinds Daniel Glass Sara J Brown Joachim Heinrich David M Evans Stephan Weidinger

Nat Genet 2015 Dec 19;47(12):1449-1456. Epub 2015 Oct 19.

Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.

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http://dx.doi.org/10.1038/ng.3424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753676PMC
December 2015

Biomarkers for atopic dermatitis: a systematic review and meta-analysis.

Curr Opin Allergy Clin Immunol 2015 Oct;15(5):453-60

aDepartment of Dermatology and Allergy, University Medical Center Utrecht, Utrecht, The Netherlands bDepartment of Dermatology, Venereology and Allergy, University Hospital Schleswig-Holstein, Campus Kiel, Germany cDepartment of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands dDepartment of Paediatric Dermatology, St John's Institute of Dermatology, Guy's and St Thomas' Hospitals NHS Foundation Trust and King's College, London, UK.

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http://dx.doi.org/10.1097/ACI.0000000000000198DOI Listing
October 2015

Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.

Nat Commun 2015 Apr 23;6:6916. Epub 2015 Apr 23.

1] State Key Laboratory Incubation Base of Dermatology, Ministry of National Science and Technology, Anhui Medical University, Hefei, Anhui 230032, China [2] Key Lab of Dermatology (Anhui Medical University), Ministry of Education, Hefei, Anhui 230032, China [3] Collaborative Innovation Center for Complex and Severe Skin Diseases, Anhui Medical University, Hefei, Anhui 230032, China [4] Department of Human Genetics, Genome Institute of Singapore, A*STAR, Singapore 138672, Singapore [5] Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore, 138672, Singapore [6] School of Life Sciences, Anhui Medical University, Hefei, Anhui 230032, China.

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http://dx.doi.org/10.1038/ncomms7916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423213PMC
April 2015

Influence of external, intrinsic and individual behaviour variables on serum 25(OH)D in a German survey.

J Photochem Photobiol B 2014 Nov 1;140:120-9. Epub 2014 Aug 1.

Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.

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http://dx.doi.org/10.1016/j.jphotobiol.2014.07.018DOI Listing
November 2014

Allergy and asthma prevention 2014.

Pediatr Allergy Immunol 2014 Oct;25(6):516-33

Pediatric Pulmonology and Allergy Unit, Children's Hospital La Fe, Instituto de Investigacion La Fe, Valencia, Spain.

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http://dx.doi.org/10.1111/pai.12272DOI Listing
October 2014

Analysis of filaggrin mutations and expression in corneal specimens from patients with or without atopic dermatitis.

Int Arch Allergy Immunol 2014 16;163(1):20-4. Epub 2013 Nov 16.

University Eye Hospital, University Medical Centre Freiburg, Freiburg im Breisgau, Germany.

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http://dx.doi.org/10.1159/000355965DOI Listing
March 2014

Alternative models of comorbidity: a framework for the interpretation of epidemiological association studies.

J Invest Dermatol 2014 Feb;134(2):303-307

Department of Dermatology, Venerology and Allergy, Excellence Cluster 'Inflammation at Interfaces', University Hospital Schleswig-Holstein, Christian-Albrechts-University, Kiel, Germany.

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http://dx.doi.org/10.1038/jid.2013.527DOI Listing
February 2014

Skin barrier in atopic dermatitis.

Front Biosci (Landmark Ed) 2014 Jan 1;19:542-56. Epub 2014 Jan 1.

Department of Dermatology, Allergology, and Venerology, University Hospital Schleswig-Holstein, Campus Kiel, Schittenhelmstrasse 7, 24105 Kiel, Germany.

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January 2014

[Association of atopic eczema and attention-deficit/hyperactivity disorder - meta-analysis of epidemiologic studies].

Z Kinder Jugendpsychiatr Psychother 2013 Jan;41(1):35-42; quiz 42-4

Institut und Poliklinik für Arbeits- und Sozialmedizin, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden.

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http://dx.doi.org/10.1024/1422-4917/a000208DOI Listing
January 2013

Molecular genetics of atopic eczema.

Chem Immunol Allergy 2012 13;96:24-29. Epub 2012 Mar 13.

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http://dx.doi.org/10.1159/000331807DOI Listing
July 2012

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.

Authors:
Lavinia Paternoster Marie Standl Chih-Mei Chen Adaikalavan Ramasamy Klaus Bønnelykke Liesbeth Duijts Manuel A Ferreira Alexessander Couto Alves Jacob P Thyssen Eva Albrecht Hansjörg Baurecht Bjarke Feenstra Patrick M A Sleiman Pirro Hysi Nicole M Warrington Ivan Curjuric Ronny Myhre John A Curtin Maria M Groen-Blokhuis Marjan Kerkhof Annika Sääf Andre Franke David Ellinghaus Regina Fölster-Holst Emmanouil Dermitzakis Stephen B Montgomery Holger Prokisch Katharina Heim Anna-Liisa Hartikainen Anneli Pouta Juha Pekkanen Alexandra I F Blakemore Jessica L Buxton Marika Kaakinen David L Duffy Pamela A Madden Andrew C Heath Grant W Montgomery Philip J Thompson Melanie C Matheson Peter Le Souëf Beate St Pourcain George Davey Smith John Henderson John P Kemp Nicholas J Timpson Panos Deloukas Susan M Ring H-Erich Wichmann Martina Müller-Nurasyid Natalija Novak Norman Klopp Elke Rodríguez Wendy McArdle Allan Linneberg Torkil Menné Ellen A Nohr Albert Hofman André G Uitterlinden Cornélia M van Duijn Fernando Rivadeneira Johan C de Jongste Ralf J P van der Valk Matthias Wjst Rain Jogi Frank Geller Heather A Boyd Jeffrey C Murray Cecilia Kim Frank Mentch Michael March Massimo Mangino Tim D Spector Veronique Bataille Craig E Pennell Patrick G Holt Peter Sly Carla M T Tiesler Elisabeth Thiering Thomas Illig Medea Imboden Wenche Nystad Angela Simpson Jouke-Jan Hottenga Dirkje Postma Gerard H Koppelman Henriette A Smit Cilla Söderhäll Bo Chawes Eskil Kreiner-Møller Hans Bisgaard Erik Melén Dorret I Boomsma Adnan Custovic Bo Jacobsson Nicole M Probst-Hensch Lyle J Palmer Daniel Glass Hakon Hakonarson Mads Melbye Deborah L Jarvis Vincent W V Jaddoe Christian Gieger David P Strachan Nicholas G Martin Marjo-Riitta Jarvelin Joachim Heinrich David M Evans Stephan Weidinger

Nat Genet 2011 Dec 25;44(2):187-92. Epub 2011 Dec 25.

Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, UK.

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http://www.tweelingenregister.org/nederlands/verslaggeving/N
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http://www.nature.com/doifinder/10.1038/ng.1017
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http://dx.doi.org/10.1038/ng.1017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272375PMC
December 2011

Genetics of atopic dermatitis.

J Dtsch Dermatol Ges 2011 Sep 26;9(9):670-6. Epub 2011 Apr 26.

Department of Dermatology and Allergy, University of Bonn, Germany.

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http://dx.doi.org/10.1111/j.1610-0387.2011.07656.xDOI Listing
September 2011

Mutual antagonism of T cells causing psoriasis and atopic eczema.

N Engl J Med 2011 Jul;365(3):231-8

Center of Allergy and Environment (ZAUM), Technische Universität and Helmholtz Center Munich, Munich, Germany.

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http://dx.doi.org/10.1056/NEJMoa1104200DOI Listing
July 2011

[Common diseases of the nails in the general practitioner's office].

MMW Fortschr Med 2011 Jun;153(23):64-7; quiz 68

Klinik für Dermatologie/Allergologie, Hochgebirgsklinik Davos, Davos.

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June 2011

Genome-wide association studies on IgE regulation: are genetics of IgE also genetics of atopic disease?

Curr Opin Allergy Clin Immunol 2010 Oct;10(5):408-17

Department of Dermatology and Allergy, Technische Universität München, Munich, Germany.

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https://insights.ovid.com/crossref?an=00130832-201010000-000
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http://dx.doi.org/10.1097/ACI.0b013e32833d7d2dDOI Listing
October 2010

Meta-analysis of filaggrin polymorphisms in eczema and asthma: robust risk factors in atopic disease.

J Allergy Clin Immunol 2009 Jun;123(6):1361-70.e7

Division of Environmental Dermatology and Allergy, Helmholtz Zentrum Munich and ZAUM-Center for Allergy and Environment, Technische Universität München, Munich, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S009167490900524
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http://dx.doi.org/10.1016/j.jaci.2009.03.036DOI Listing
June 2009

Filaggrin variants confer susceptibility to asthma.

J Allergy Clin Immunol 2008 May 8;121(5):1294-5; author reply 1295-6. Epub 2008 Apr 8.

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http://dx.doi.org/10.1016/j.jaci.2008.02.039DOI Listing
May 2008

Filaggrin mutations, atopic eczema, hay fever, and asthma in children.

J Allergy Clin Immunol 2008 May 8;121(5):1203-1209.e1. Epub 2008 Apr 8.

Department of Dermatology and Allergy, Technical University Munich, Munich, Germany.

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http://dx.doi.org/10.1016/j.jaci.2008.02.014DOI Listing
May 2008

Filaggrin loss-of-function mutations and association with allergic diseases.

Pharmacogenomics 2008 Apr;9(4):399-413

Division of Environmental Dermatology and Allergy, Helmholtz Zentrum Muenchen, Neuherberg and ZAUM-Center for Allergy and Environment, Technical University Munich, Biedersteiner Str. 29, 80802 Munich, Germany.

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http://dx.doi.org/10.2217/14622416.9.4.399DOI Listing
April 2008

Toward a major risk factor for atopic eczema: meta-analysis of filaggrin polymorphism data.

J Allergy Clin Immunol 2007 Dec 5;120(6):1406-12. Epub 2007 Nov 5.

Institute for Medical Statistics and Epidemiology (IMSE), Technical University Munich (TUM), Munich, Germany.

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http://dx.doi.org/10.1016/j.jaci.2007.08.067DOI Listing
December 2007