Stephan Ossowski

Stephan Ossowski

UNVERIFIED PROFILE

Are you Stephan Ossowski?   Register this Author

Register author
Stephan Ossowski

Stephan Ossowski

Publications by authors named "Stephan Ossowski"

Are you Stephan Ossowski?   Register this Author

63Publications

1752Reads

26Profile Views

Radiogenomics in head and neck cancer: correlation of radiomic heterogeneity and somatic mutations in TP53, FAT1 and KMT2D.

Strahlenther Onkol 2019 Sep 23;195(9):771-779. Epub 2019 May 23.

Department of Radiation Oncology, Medical Faculty and University Hospital, Eberhard Karls University, Hoppe-Seyler-Straße 3, 72076, Tübingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00066-019-01478-xDOI Listing
September 2019

eDiVA-Classification and prioritization of pathogenic variants for clinical diagnostics.

Hum Mutat 2019 Jul 21;40(7):865-878. Epub 2019 May 21.

Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.23772DOI Listing
July 2019

Allele balance bias identifies systematic genotyping errors and false disease associations.

Hum Mutat 2019 Jan 23;40(1):115-126. Epub 2018 Nov 23.

Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/humu.23674
Publisher Site
http://dx.doi.org/10.1002/humu.23674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587442PMC
January 2019

Circulating cell-free DNA: A potential biomarker to differentiate inflammation and infection during radiochemotherapy.

Radiother Oncol 2018 12 7;129(3):575-581. Epub 2018 Aug 7.

Institute of Medical Genetics and Applied Genomics, Medical Faculty and University Hospital, Eberhard Karls University, Tübingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.radonc.2018.07.016DOI Listing
December 2018

Tissue-specific DNA methylation loss during ageing and carcinogenesis is linked to chromosome structure, replication timing and cell division rates.

Nucleic Acids Res 2018 08;46(14):7022-7039

Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona 08003, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gky498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101545PMC
August 2018

Negative selection in tumor genome evolution acts on essential cellular functions and the immunopeptidome.

Genome Biol 2018 05 31;19(1):67. Epub 2018 May 31.

Design of Biological Systems Group, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, 08003, Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13059-018-1434-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984361PMC
May 2018

Signatures of positive selection reveal a universal role of chromatin modifiers as cancer driver genes.

Sci Rep 2017 10 13;7(1):13124. Epub 2017 Oct 13.

Bioinformatics and Genomics Program, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, 08003, Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-017-12888-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640613PMC
October 2017

Spinal Cord Transcriptomic and Metabolomic Analysis after Excitotoxic Injection Injury Model of Syringomyelia.

J Neurotrauma 2017 02 13;34(3):720-733. Epub 2016 Oct 13.

1 Department of Chemical and Biomolecular Engineering, University of Akron , Akron, Ohio.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/neu.2015.4341DOI Listing
February 2017

Identification of Gene Mutations and Fusion Genes in Patients with Sézary Syndrome.

J Invest Dermatol 2016 07 30;136(7):1490-1499. Epub 2016 Mar 30.

Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, Barcelona 08003, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; CIBER in Epidemiology and Public Health (CIBERESP), Barcelona, Spain; Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain; Experimental Genetics, Sidra Medical and Research Centre, Doha, Qatar. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jid.2016.03.024DOI Listing
July 2016

Chromosome-level assembly of Arabidopsis thaliana Ler reveals the extent of translocation and inversion polymorphisms.

Proc Natl Acad Sci U S A 2016 07 27;113(28):E4052-60. Epub 2016 Jun 27.

Department of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1607532113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948326PMC
July 2016

Missense mutations in TENM4, a regulator of axon guidance and central myelination, cause essential tremor.

Hum Mol Genet 2015 Oct 17;24(20):5677-86. Epub 2015 Jul 17.

Bioinformatics and Genomics Program, Centre for Genomic Regulation (CRG), Barcelona, Spain, Universitat Pompeu Fabra (UPF), Barcelona, Spain, Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain, CRG CIBER de Epidemiología y Salud Pública (CIBERESP), Barcelona, Catalonia 08003, Spain, Dexeus Women's Health, University Hospital Quiron-Dexeus, Barcelona, Catalonia 08028, Spain

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddv281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692992PMC
October 2015

Jitterbug: somatic and germline transposon insertion detection at single-nucleotide resolution.

BMC Genomics 2015 Oct 12;16:768. Epub 2015 Oct 12.

Genomic and Epigenomic Variation in Disease Group, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Dr. Aiguader 88, 08003, Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12864-015-1975-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603299PMC
October 2015

Targeted next-generation sequencing in steroid-resistant nephrotic syndrome: mutations in multiple glomerular genes may influence disease severity.

Eur J Hum Genet 2015 Sep 19;23(9):1192-9. Epub 2014 Nov 19.

1] Molecular Biology Laboratory, Fundació Puigvert, Instituto de Investigaciones Biomédicas Sant Pau (IIB-Sant Pau), Universitat Autònoma de Barcelona, REDinREN, Instituto de Investigación Carlos III, Barcelona, Catalonia, Spain [2] Nephrology Department, Fundació Puigvert, Instituto de Investigaciones Biomédicas Sant Pau (IIB-Sant Pau), Universitat Autònoma de Barcelona, REDinREN, Instituto de Investigación Carlos III, Barcelona, Catalonia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ejhg.2014.252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538209PMC
September 2015

Analysis of a long-term outbreak of XDR Pseudomonas aeruginosa: a molecular epidemiological study.

J Antimicrob Chemother 2015 May 11;70(5):1322-30. Epub 2015 Jan 11.

Institute of Medical Microbiology and Hygiene, University of Tübingen, Tübingen, Germany German Center for Infection Research (DZIF), partner site Tübingen, Tübingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jac/dku546DOI Listing
May 2015

Chromatin-wide profiling of DYRK1A reveals a role as a gene-specific RNA polymerase II CTD kinase.

Mol Cell 2015 Feb 22;57(3):506-20. Epub 2015 Jan 22.

Gene Regulation, Stem Cells and Cancer Programme, Centre for Genomic Regulation (CRG), Dr Aiguader 88, 08003 Barcelona, Spain; Universitat Pompeu Fabra (UPF), Dr Aiguader 88, 08003 Barcelona, Spain; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), Passeig Lluís Companys 23, 08010 Barcelona, Spain. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2014.12.026DOI Listing
February 2015

A shift from magnitude to sign epistasis during adaptive evolution of a bacterial social trait.

Evolution 2014 09 15;68(9):2701-8. Epub 2014 Jul 15.

Department of Biology, Indiana University, 1001 E. Third Street, Bloomington, Indiana, 47401.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/evo.12467DOI Listing
September 2014

Diagnosis of autosomal dominant polycystic kidney disease using efficient PKD1 and PKD2 targeted next-generation sequencing.

Mol Genet Genomic Med 2014 Sep 23;2(5):412-21. Epub 2014 May 23.

Molecular Biology Laboratory, Fundació Puigvert, Instituto de Investigaciones Biomédicas Sant Pau (IIB-Sant Pau), Universitat Autònoma de Barcelona REDinREN, Instituto de Investigación Carlos III, Barcelona, Catalonia, Spain ; Nephrology Department, Fundació Puigvert, Instituto de Investigaciones Biomédicas Sant Pau (IIB-Sant Pau), Universitat Autònoma de Barcelona REDinREN, Instituto de Investigación Carlos III, Barcelona, Catalonia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mgg3.82DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190876PMC
September 2014

Accurate molecular diagnosis of phenylketonuria and tetrahydrobiopterin-deficient hyperphenylalaninemias using high-throughput targeted sequencing.

Eur J Hum Genet 2014 Apr 14;22(4):528-34. Epub 2013 Aug 14.

1] Genomics and Disease Group, Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain [2] Universitat Pompeu Fabra (UPF), Barcelona, Spain [3] Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain [4] CIBER in Epidemiology and Public Health (CIBERESP), Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ejhg.2013.175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953903PMC
April 2014

A genomic-scale artificial microRNA library as a tool to investigate the functionally redundant gene space in Arabidopsis.

Plant Cell 2013 Aug 16;25(8):2848-63. Epub 2013 Aug 16.

Division of Biological Sciences, Cell and Developmental Biology Section, University of California San Diego, La Jolla, California 92093-0116.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1105/tpc.113.112805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784584PMC
August 2013

Artificial microRNAs for specific gene silencing in rice.

Methods Mol Biol 2013 ;956:131-49

Department of Molecular Biology, Max Planck Institute for Developmental Biology, Tübingen, Germany.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/978-1-62703-194-3_11
Publisher Site
http://dx.doi.org/10.1007/978-1-62703-194-3_11DOI Listing
April 2013

Impaired sterol ester synthesis alters the response of Arabidopsis thaliana to Phytophthora infestans.

Plant J 2013 Feb 12;73(3):456-68. Epub 2012 Dec 12.

Department of Stress and Developmental Biology, Leibniz Institute of Plant Biochemistry, Weinberg 3, D-06120, Halle (Saale), Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/tpj.12046DOI Listing
February 2013

Complementation contributes to transcriptome complexity in maize (Zea mays L.) hybrids relative to their inbred parents.

Genome Res 2012 Dec 19;22(12):2445-54. Epub 2012 Oct 19.

Institute of Crop Science and Resource Conservation, Division of Crop Functional Genomics, University of Bonn, 53113 Bonn, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.138461.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514674PMC
December 2012

The cis-regulatory code of Hox function in Drosophila.

EMBO J 2012 Aug 10;31(15):3323-33. Epub 2012 Jul 10.

CellNetworks-Cluster of Excellence and Centre for Organismal Studies (COS) Heidelberg, Heidelberg University, Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/emboj.2012.179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411081PMC
August 2012

Fitness of Arabidopsis thaliana mutation accumulation lines whose spontaneous mutations are known.

Evolution 2012 Jul 21;66(7):2335-9. Epub 2012 Feb 21.

Department of Biology, College of Charleston, Charleston, South Carolina 29401, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1558-5646.2012.01583.xDOI Listing
July 2012

Genome-wide comparison of nucleotide-binding site-leucine-rich repeat-encoding genes in Arabidopsis.

Plant Physiol 2011 Oct 2;157(2):757-69. Epub 2011 Aug 2.

Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tuebingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1104/pp.111.181990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192553PMC
October 2011

Reference-guided assembly of four diverse Arabidopsis thaliana genomes.

Proc Natl Acad Sci U S A 2011 Jun 6;108(25):10249-54. Epub 2011 Jun 6.

Department of Molecular Biology, Max Planck Institute for Developmental Biology, D-72076 Tübingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1107739108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121819PMC
June 2011

Simultaneous alignment of short reads against multiple genomes.

Genome Biol 2009 17;10(9):R98. Epub 2009 Sep 17.

Department of Molecular Biology, Max Planck Institute for Developmental Biology, Spemannstrasse 37-39, D-72076 Tübingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/gb-2009-10-9-r98DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768987PMC
February 2010

Directed gene silencing with artificial microRNAs.

Methods Mol Biol 2010 ;592:71-88

Institut de Biologie Moléculaire des Plantes (CNRS), Strasbourg, Cedex, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-60327-005-2_6DOI Listing
January 2010

The rate and molecular spectrum of spontaneous mutations in Arabidopsis thaliana.

Science 2010 Jan;327(5961):92-4

Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878865PMC
http://dx.doi.org/10.1126/science.1180677DOI Listing
January 2010

Transcriptional control of gene expression by microRNAs.

Cell 2010 Jan;140(1):111-22

Plant Biotechnology, Faculty of Biology, University of Freiburg, Schaenzlestrasse 1, 79104 Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2009.12.023DOI Listing
January 2010

Selective epigenetic control of retrotransposition in Arabidopsis.

Nature 2009 Sep 6;461(7262):427-30. Epub 2009 Sep 6.

Department of Plant Biology, University of Geneva, Sciences III, 30 Quai Ernest-Ansermet, CH-1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature08328DOI Listing
September 2009

Highly specific gene silencing by artificial microRNAs in the unicellular alga Chlamydomonas reinhardtii.

Plant J 2009 Apr 19;58(1):165-74. Epub 2009 Jan 19.

Department of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-313X.2008.03767.xDOI Listing
April 2009

Sequencing of natural strains of Arabidopsis thaliana with short reads.

Genome Res 2008 Dec 25;18(12):2024-33. Epub 2008 Sep 25.

Department of Molecular Biology, Max Planck Institute for Developmental Biology, Tübingen, Germany.

View Article

Download full-text PDF

Source
http://www.genome.org/cgi/doi/10.1101/gr.080200.108
Publisher Site
http://dx.doi.org/10.1101/gr.080200.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593571PMC
December 2008

Specific gene silencing by artificial MicroRNAs in Physcomitrella patens: an alternative to targeted gene knockouts.

Plant Physiol 2008 Oct 27;148(2):684-93. Epub 2008 Aug 27.

Plant Biotechnology, Faculty of Biology, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1104/pp.108.128025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556843PMC
October 2008

Optimal spliced alignments of short sequence reads.

Bioinformatics 2008 Aug;24(16):i174-80

Friedrich Miescher Laboratory, Max Planck Society, Spemannstr 39, 72076 Tübingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btn300DOI Listing
August 2008

Gene silencing in plants using artificial microRNAs and other small RNAs.

Plant J 2008 Feb;53(4):674-90

Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-313X.2007.03328.xDOI Listing
February 2008

Recombination and linkage disequilibrium in Arabidopsis thaliana.

Nat Genet 2007 Sep 5;39(9):1151-5. Epub 2007 Aug 5.

Molecular and Computational Biology, University of Southern California, Los Angeles, California 90089, USA.

View Article

Download full-text PDF

Source
http://www.thefootjournal.com/trends/genetics/pdf/S0168-9525
Web Search
http://www.nature.com/doifinder/10.1038/ng2115
Publisher Site
http://dx.doi.org/10.1038/ng2115DOI Listing
September 2007

Text similarity: an alternative way to search MEDLINE.

Bioinformatics 2006 Sep 22;22(18):2298-304. Epub 2006 Aug 22.

University of Texas Southwestern Medical Center, Eugene McDermott Center for Human Growth and Development, Division for Translational Research 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btl388DOI Listing
September 2006

Highly specific gene silencing by artificial microRNAs in Arabidopsis.

Plant Cell 2006 May 10;18(5):1121-33. Epub 2006 Mar 10.

Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.

View Article

Download full-text PDF

Source
http://www.plantcell.org/content/18/5/1121.full.pdf+html
Web Search
http://www.plantcell.org/cgi/doi/10.1105/tpc.105.039834
Publisher Site
http://dx.doi.org/10.1105/tpc.105.039834DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456875PMC
May 2006