Stephan Michel

Stephan Michel

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Stephan Michel

Stephan Michel

Publications by authors named "Stephan Michel"

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49Publications

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Differential Phase Arrangement of Cellular Clocks along the Tonotopic Axis of the Mouse Cochlea Ex Vivo.

Curr Biol 2017 Sep 17;27(17):2623-2629.e2. Epub 2017 Aug 17.

Department of Physiology and Pharmacology, Karolinska Institutet, 17177 Stockholm, Sweden. Electronic address:

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September 2017

Evidence for Weakened Intercellular Coupling in the Mammalian Circadian Clock under Long Photoperiod.

PLoS One 2016 22;11(12):e0168954. Epub 2016 Dec 22.

Department of Molecular Cell Biology, Laboratory for Neurophysiology, Leiden University Medical Center, Leiden, The Netherlands.

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July 2017

Stereopure Functionalized Benzosultams via Ruthenium(II)-Catalyzed Dynamic Kinetic Resolution-Asymmetric Transfer Hydrogenation.

Org Lett 2017 04 13;19(8):2042-2045. Epub 2017 Apr 13.

National Institute of Chemistry, Hajdrihova 19, 1001 Ljubljana, Slovenia.

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April 2017

Photoperiod Modulates Fast Delayed Rectifier Potassium Currents in the Mammalian Circadian Clock.

ASN Neuro 2016 10 3;8(5). Epub 2016 Oct 3.

Leiden University Medical Center, Leiden, The Netherlands.

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October 2016

γ-Sultam-cored N,N-ligands in the ruthenium(ii)-catalyzed asymmetric transfer hydrogenation of aryl ketones.

Org Biomol Chem 2016 Feb;14(6):2112-20

National Institute of Chemistry, Hajdrihova 19, 1001 Ljubljana, Slovenia.

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February 2016

Neurophysiological analysis of the suprachiasmatic nucleus: a challenge at multiple levels.

Methods Enzymol 2015 26;552:75-102. Epub 2014 Dec 26.

Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands.

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November 2015

Role of vasoactive intestinal peptide in the light input to the circadian system.

Eur J Neurosci 2015 Jul 25;42(2):1839-48. Epub 2015 May 25.

Department of Psychiatry & Biobehavioral Sciences, University of California - Los Angeles, Los Angeles, CA, 90024, USA.

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July 2015

Age-related changes in large-conductance calcium-activated potassium channels in mammalian circadian clock neurons.

Neurobiol Aging 2015 Jun 31;36(6):2176-83. Epub 2015 Jan 31.

Laboratory of Neurophysiology, Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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June 2015

Seasonal induction of GABAergic excitation in the central mammalian clock.

Proc Natl Acad Sci U S A 2014 Jul 16;111(26):9627-32. Epub 2014 Jun 16.

Department of Molecular Cell Biology, Laboratory of Neurophysiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands

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July 2014

Efficient asymmetric syntheses of 1-phenyl-phosphindane, derivatives, and 2- or 3-oxa analogues: mission accomplished.

Org Lett 2014 May 28;16(10):2688-91. Epub 2014 Apr 28.

National Institute of Chemistry , Hajdrihova 19, 1000 Ljubljana, Slovenia.

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May 2014

Aging of the suprachiasmatic clock.

Neuroscientist 2014 Feb 7;20(1):44-55. Epub 2013 Aug 7.

1Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands.

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February 2014

Enhanced phase resetting in the synchronized suprachiasmatic nucleus network.

J Biol Rhythms 2014 Feb;29(1):4-15

Laboratory for Neurophysiology, Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, the Netherlands.

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February 2014

P-stereogenic phospholanes or phosphorinanes from o-biarylylphosphines: two bridges not too far.

J Org Chem 2013 May 6;78(10):4665-73. Epub 2013 May 6.

National Institute of Chemistry, Hajdrihova 19, SI-1000 Ljubljana, Slovenia.

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May 2013

Asymmetric transfer hydrogenation of 1-naphthyl ketones by an ansa-Ru(II) complex of a DPEN-SO2N(Me)-(CH2)2(η(6)-p-Tol) combined ligand.

Org Lett 2013 Apr 19;15(7):1614-7. Epub 2013 Mar 19.

National Institute of Chemistry, Hajdrihova 19, SI-1000 Ljubljana, Slovenia.

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April 2013

Mechanism of bilateral communication in the suprachiasmatic nucleus.

Eur J Neurosci 2013 Mar 14;37(6):964-71. Epub 2013 Jan 14.

Laboratory for Neurophysiology, Department of Molecular Cell Biology, Leiden University Medical Center, LUMC PZ S5-P, PO 9600, 2300 RC, Leiden, The Netherlands.

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March 2013

Dynamic neuronal network organization of the circadian clock and possible deterioration in disease.

Prog Brain Res 2012 ;199:143-62

Laboratory for Neurophysiology, Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands.

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January 2013

Role of vasoactive intestinal peptide in seasonal encoding by the suprachiasmatic nucleus clock.

Eur J Neurosci 2012 May 19;35(9):1466-74. Epub 2012 Apr 19.

Laboratory of Neurophysiology, Department of Molecular Cell Biology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands.

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May 2012

Evidence for neuronal desynchrony in the aged suprachiasmatic nucleus clock.

J Neurosci 2012 Apr;32(17):5891-9

Department of Neurophysiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.

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April 2012

Phase resetting of the mammalian circadian clock relies on a rapid shift of a small population of pacemaker neurons.

PLoS One 2011 22;6(9):e25437. Epub 2011 Sep 22.

Laboratory for Neurophysiology, Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands.

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February 2012

Profiling the tuneable R-SMS-Phos structure in the rhodium(I)-catalyzed hydrogenation of olefins: the last stand?

Org Biomol Chem 2011 Jul 31;9(14):5266-71. Epub 2011 May 31.

National Institute of Chemistry, Hajdrihova 19, SI-1001, Ljubljana, Slovenia.

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July 2011

Daily and seasonal adaptation of the circadian clock requires plasticity of the SCN neuronal network.

Eur J Neurosci 2010 Dec;32(12):2143-51

Department of Molecular Cell Biology, Laboratory for Neurophysiology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands.

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December 2010

Impact on hydrogenation catalytic cycle of the R groups' cyclic feature in "R-SMS-Phos".

Org Lett 2010 Jul;12(13):3022-5

Laboratory of Organic and Medicinal Chemistry, National Institute of Chemistry, Hajdrihova 19, SI-1001 Ljubljana, Slovenia.

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July 2010

Tetracysteine-tagged prion protein allows discrimination between the native and converted forms.

FEBS J 2010 May 19;277(9):2038-50. Epub 2010 Mar 19.

Department of Biotechnology, National Institute of Chemistry, Ljubljana, Slovenia.

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May 2010

Heavyweight "R-SMS-Phos" ligands in the olefins' hydrogenation arena.

Org Lett 2010 Mar;12(6):1296-9

Laboratory of Organic and Medicinal Chemistry, National Institute of Chemistry, Hajdrihova 19, SI-1001 Ljubljana, Slovenia.

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March 2010

Circadian regulation of a-type potassium currents in the suprachiasmatic nucleus.

J Neurophysiol 2010 Feb 25;103(2):632-40. Epub 2009 Nov 25.

Department of Psychiatry and Biobehavioral Sciences, University of California-Los Angeles, Los Angeles, CA 90024-1759, USA.

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February 2010

Phase of the electrical activity rhythm in the SCN in vitro not influenced by preparation time.

Chronobiol Int 2009 Aug;26(6):1075-89

Department of Molecular Cell Biology, Laboratory for Neurophysiology, Leiden University Medical Center, Leiden, The Netherlands.

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August 2009

Phase shifting capacity of the circadian pacemaker determined by the SCN neuronal network organization.

PLoS One 2009 23;4(3):e4976. Epub 2009 Mar 23.

Department of Molecular Cell Biology, Laboratory for Neurophysiology, Leiden University Medical Center, Leiden, The Netherlands.

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April 2009

Enhanced circadian phase resetting in R192Q Cav2.1 calcium channel migraine mice.

Ann Neurol 2008 Sep;64(3):315-24

Laboratory for Neurophysiology, Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, the Netherlands.

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September 2008

Organization of cell and tissue circadian pacemakers: a comparison among species.

Brain Res Rev 2008 Jun 1;58(1):18-47. Epub 2007 Nov 1.

Laboratory for Neurophysiology, Department of Molecular Cell Biology, Leiden University Medical Center, Postal zone S5-P, P.O. Box 9600, 2300 RC Leiden, The Netherlands.

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June 2008

Study of the reaction of bulky aryllithium reagents with 3,4-dimethyl-2,5-diphenyl-1,3,2-oxazaphospholidine-2-borane derived from ephedrine.

J Org Chem 2007 Oct 18;72(21):8010-8. Epub 2007 Sep 18.

PhosPhoenix SARL, 115, rue de l'Abbé Groult, F-75015 Paris, France.

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October 2007

Processing of daily and seasonal light information in the mammalian circadian clock.

Gen Comp Endocrinol 2007 Jun-Jul;152(2-3):159-64. Epub 2007 Jan 25.

Laboratory for Neurophysiology, Department of Molecular Cell Biology, Leiden University Medical Center, Postal Zone S5-P, P.O. Box 9600, 2300 RC Leiden, The Netherlands.

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August 2007

Seasonal encoding by the circadian pacemaker of the SCN.

Curr Biol 2007 Mar 22;17(5):468-73. Epub 2007 Feb 22.

Department of Molecular Cell Biology, Lab for Neurophysiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.

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March 2007

Highly enantioselective transfer hydrogenation of fluoroalkyl ketones.

Org Lett 2006 Dec;8(26):5935-8

Laboratory of Organic and Medicinal Chemistry, National Institute of Chemistry, Hajdrihova 19, SI-1001 Ljubljana, Slovenia.

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December 2006

Regulation of glutamatergic signalling by PACAP in the mammalian suprachiasmatic nucleus.

BMC Neurosci 2006 Feb 16;7:15. Epub 2006 Feb 16.

Department of Molecular Cell Biology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands.

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February 2006

Fast delayed rectifier potassium current is required for circadian neural activity.

Nat Neurosci 2005 May 24;8(5):650-6. Epub 2005 Apr 24.

Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, 760 Westwood Plaza, Los Angeles, California 90024-1759, USA.

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May 2005

A GABAergic mechanism is necessary for coupling dissociable ventral and dorsal regional oscillators within the circadian clock.

Curr Biol 2005 May;15(10):886-93

Department of Neurophysiology, Leiden University Medical Center, Wassenaarseweg 62, Post Office Box 9604, 2300 RC Leiden, The Netherlands.

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May 2005

Circadian rhythm in inhibitory synaptic transmission in the mouse suprachiasmatic nucleus.

J Neurophysiol 2004 Jul 18;92(1):311-9. Epub 2004 Feb 18.

Mental Retardation Research Center, Department of Psychiatry and Biobehavioral Science, University of California-Los Angeles, 760 Westwood Plaza, Los Angeles, CA 90024-1759, USA.

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July 2004

Synaptic stimulation of Aplysia peptidergic neurons can activate hormone secretion in the absence of an afterdischarge.

Neurosci Lett 2004 May;362(3):249-52

Department of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.

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May 2004

Post-afterdischarge depolarization does not stimulate prolonged neurohormone secretion but is required for activity-dependent stimulation of neurohormone biosynthesis from peptidergic neurons.

Endocrinology 2004 Apr 22;145(4):1678-84. Epub 2003 Dec 22.

Department of Physiology, David Geffen School of Medicine at University of California-Los Angeles, 90095-1751, USA.

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April 2004

Activity-dependent regulation of neurohormone synthesis and its impact on reproductive behavior in aplysia.

Biol Reprod 2004 Feb 1;70(2):277-81. Epub 2003 Oct 1.

Department of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095-1751, USA.

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February 2004

Disrupted circadian rhythms in VIP- and PHI-deficient mice.

Am J Physiol Regul Integr Comp Physiol 2003 Nov 10;285(5):R939-49. Epub 2003 Jul 10.

Mental Retardation Res. Ctr., Univ. of California - Los Angeles, 760 Westwood Plaza, Los Angeles, CA 90024-1759, USA.

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November 2003

An activity-dependent switch to cap-independent translation triggered by eIF4E dephosphorylation.

Nat Neurosci 2003 Mar;6(3):219-20

Department of Neurology and Neurosurgery, McGill University, Montreal Neurological Institute, 3801 University St., Montreal, Quebec H3A-2B4, Canada.

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March 2003

Neurohormone secretion persists after post-afterdischarge membrane depolarization and cytosolic calcium elevation in peptidergic neurons in intact nervous tissue.

J Neurosci 2002 Oct;22(20):9063-9

Department of Physiology, David Geffin School of Medicine at University of California at Los Angeles, Los Angeles, California 90095, USA.

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October 2002

Excitatory mechanisms in the suprachiasmatic nucleus: the role of AMPA/KA glutamate receptors.

J Neurophysiol 2002 Aug;88(2):817-28

Mental Retardation Research Center, Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles 90024-1759, USA.

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August 2002