Stephan Menzel

Clinical Genetics Branch, Division of Clinical Epidemiology and Genetics, National Cancer Institute, National Institutes of Health/DCEG/CGB Branch, 9609 Medical Center Dr, Rm 6E452, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1111/bjh.12399	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720816	PMC

August 2013

4 Reads

2 Citations

4.711 Impact Factor

HbA2 levels in normal adults are influenced by two distinct genetic mechanisms.

Authors:

Stephan Menzel Chad Garner Helen Rooks Tim D Spector Swee Lay Thein

Br J Haematol 2013 Jan 9;160(1):101-5. Epub 2012 Oct 9.

Molecular Haematology, James Black Centre, King's College London, 125 Coldharbour Lane, London, UK.

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http://dx.doi.org/10.1111/bjh.12084	DOI Listing

January 2013

1 Read

10 Citations

4.711 Impact Factor

Multiple loci are associated with white blood cell phenotypes.

Authors:

Michael A Nalls David J Couper Toshiko Tanaka Frank J A van Rooij Ming-Huei Chen Albert V Smith Daniela Toniolo Neil A Zakai Qiong Yang Andreas Greinacher Andrew R Wood Melissa Garcia Paolo Gasparini Yongmei Liu Thomas Lumley Aaron R Folsom Alex P Reiner Christian Gieger Vasiliki Lagou Janine F Felix Henry Völzke Natalia A Gouskova Alessandro Biffi Angela Döring Uwe Völker Sean Chong Kerri L Wiggins Augusto Rendon Abbas Dehghan Matt Moore Kent Taylor James G Wilson Guillaume Lettre Albert Hofman Joshua C Bis Nicola Pirastu Caroline S Fox Christa Meisinger Jennifer Sambrook Sampath Arepalli Matthias Nauck Holger Prokisch Jonathan Stephens Nicole L Glazer L Adrienne Cupples Yukinori Okada Atsushi Takahashi Yoichiro Kamatani Koichi Matsuda Tatsuhiko Tsunoda Toshihiro Tanaka Michiaki Kubo Yusuke Nakamura Kazuhiko Yamamoto Naoyuki Kamatani Michael Stumvoll Anke Tönjes Inga Prokopenko Thomas Illig Kushang V Patel Stephen F Garner Brigitte Kuhnel Massimo Mangino Ben A Oostra Swee Lay Thein Josef Coresh H-Erich Wichmann Stephan Menzel JingPing Lin Giorgio Pistis André G Uitterlinden Tim D Spector Alexander Teumer Gudny Eiriksdottir Vilmundur Gudnason Stefania Bandinelli Timothy M Frayling Aravinda Chakravarti Cornelia M van Duijn David Melzer Willem H Ouwehand Daniel Levy Eric Boerwinkle Andrew B Singleton Dena G Hernandez Dan L Longo Nicole Soranzo Jacqueline C M Witteman Bruce M Psaty Luigi Ferrucci Tamara B Harris Christopher J O'Donnell Santhi K Ganesh

PLoS Genet 2011 Jun 30;7(6):e1002113. Epub 2011 Jun 30.

Laboratory of Neurogenetics, Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1002113	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128114	PMC

June 2011

58 Reads

59 Citations

Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach.

Authors:

Belinda Giardine Joseph Borg Douglas R Higgs Kenneth R Peterson Sjaak Philipsen Donna Maglott Belinda K Singleton David J Anstee A Nazli Basak Barnaby Clark Flavia C Costa Paula Faustino Halyna Fedosyuk Alex E Felice Alain Francina Renzo Galanello Monica V E Gallivan Marianthi Georgitsi Richard J Gibbons Piero C Giordano Cornelis L Harteveld James D Hoyer Martin Jarvis Philippe Joly Emmanuel Kanavakis Panagoula Kollia Stephan Menzel Webb Miller Kamran Moradkhani John Old Adamantia Papachatzopoulou Manoussos N Papadakis Petros Papadopoulos Sonja Pavlovic Lucia Perseu Milena Radmilovic Cathy Riemer Stefania Satta Iris Schrijver Maja Stojiljkovic Swee Lay Thein Jan Traeger-Synodinos Ray Tully Takahito Wada John S Waye Claudia Wiemann Branka Zukic David H K Chui Henri Wajcman Ross C Hardison George P Patrinos

Nat Genet 2011 Mar 20;43(4):295-301. Epub 2011 Mar 20.

Pennsylvania State University, Center for Comparative Genomics and Bioinformatics, University Park, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.785	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878152	PMC

March 2011

57 Reads

44 Citations

29.352 Impact Factor

Genetics of fetal hemoglobin in Tanzanian and British patients with sickle cell anemia.

Authors:

Julie Makani Stephan Menzel Siana Nkya Sharon E Cox Emma Drasar Deogratius Soka Albert N Komba Josephine Mgaya Helen Rooks Nisha Vasavda Gregory Fegan Charles R Newton Martin Farrall Swee Lay Thein

Blood 2011 Jan 10;117(4):1390-2. Epub 2010 Nov 10.

Muhimbili University of Health and Allied Sciences, Dar-es-Salaam, Tanzania.

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http://dx.doi.org/10.1182/blood-2010-08-302703	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555384	PMC

January 2011

20 Reads

33 Citations

10.452 Impact Factor

A twins heritability study on alpha hemoglobin stabilizing protein (AHSP) expression variability.

Authors:

Mei I Lai Chad Garner Jie Jiang Nicholas Silver Steve Best Stephan Menzel Swee L Thein

Twin Res Hum Genet 2010 Dec;13(6):567-72

Department of Pathology, Universiti Putra Malaysia, Malaysia.

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http://dx.doi.org/10.1375/twin.13.6.567	DOI Listing

December 2010

36 Reads

1.920 Impact Factor

Experimental generation of SNP haplotype signatures in patients with sickle cell anaemia.

Authors:

Stephan Menzel Jian Qin Nisha Vasavda Swee Lay Thein Ramesh Ramakrishnan

PLoS One 2010 Sep 24;5(9):e13004. Epub 2010 Sep 24.

Division of Gene and Cell Based Therapy, King's College London School of Medicine, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013004	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945316	PMC

September 2010

11 Reads

2 Citations

3.234 Impact Factor

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.

Authors:

Nicole Soranzo Tim D Spector Massimo Mangino Brigitte Kühnel Augusto Rendon Alexander Teumer Christina Willenborg Benjamin Wright Li Chen Mingyao Li Perttu Salo Benjamin F Voight Philippa Burns Roman A Laskowski Yali Xue Stephan Menzel David Altshuler John R Bradley Suzannah Bumpstead Mary-Susan Burnett Joseph Devaney Angela Döring Roberto Elosua Stephen E Epstein Wendy Erber Mario Falchi Stephen F Garner Mohammed J R Ghori Alison H Goodall Rhian Gwilliam Hakon H Hakonarson Alistair S Hall Naomi Hammond Christian Hengstenberg Thomas Illig Inke R König Christopher W Knouff Ruth McPherson Olle Melander Vincent Mooser Matthias Nauck Markku S Nieminen Christopher J O'Donnell Leena Peltonen Simon C Potter Holger Prokisch Daniel J Rader Catherine M Rice Robert Roberts Veikko Salomaa Jennifer Sambrook Stefan Schreiber Heribert Schunkert Stephen M Schwartz Jovana Serbanovic-Canic Juha Sinisalo David S Siscovick Klaus Stark Ida Surakka Jonathan Stephens John R Thompson Uwe Völker Henry Völzke Nicholas A Watkins George A Wells H-Erich Wichmann David A Van Heel Chris Tyler-Smith Swee Lay Thein Sekar Kathiresan Markus Perola Muredach P Reilly Alexandre F R Stewart Jeanette Erdmann Nilesh J Samani Christa Meisinger Andreas Greinacher Panos Deloukas Willem H Ouwehand Christian Gieger

Nat Genet 2009 Nov 11;41(11):1182-90. Epub 2009 Oct 11.

Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.

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http://dx.doi.org/10.1038/ng.467	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108459	PMC

November 2009

64 Reads

197 Citations

29.352 Impact Factor

Control of fetal hemoglobin: new insights emerging from genomics and clinical implications.

Authors:

Swee Lay Thein Stephan Menzel Mark Lathrop Chad Garner

Hum Mol Genet 2009 Oct;18(R2):R216-23

Division of Gene and Cell Based Therapy, King's College London School of Medicine, Molecular Haematology, Denmark Hill Campus, London SE5 9NU, UK.

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http://dx.doi.org/10.1093/hmg/ddp401	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758709	PMC

October 2009

9 Reads

75 Citations

6.393 Impact Factor

Association of sickle avascular necrosis with bone morphogenic protein 6.

Authors:

Pinar Ulug Nisha Vasavda Moji Awogbade Juliette Cunningham Stephan Menzel Swee Lay Thein

Ann Hematol 2009 Aug 18;88(8):803-5. Epub 2008 Dec 18.

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http://dx.doi.org/10.1007/s00277-008-0659-5	DOI Listing

August 2009

24 Reads

6 Citations

2.634 Impact Factor

Discovering the genetics underlying foetal haemoglobin production in adults.

Authors:

Swee Lay Thein Stephan Menzel

Br J Haematol 2009 May 2;145(4):455-67. Epub 2008 Mar 2.

King's College London School of Medicine, Molecular Haematology, Division of Gene and Cell Based Therapy, Denmark Hill Campus, London, UK.

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http://dx.doi.org/10.1111/j.1365-2141.2009.07650.x	DOI Listing

May 2009

46 Citations

4.711 Impact Factor

A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function.

Blood 2009 Apr 12;113(16):3831-7. Epub 2009 Feb 12.

Human Genetics Department, Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom.

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http://dx.doi.org/10.1182/blood-2008-10-184234	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714088	PMC

April 2009

15 Reads

43 Citations

10.452 Impact Factor

Ethnic differences in F cell levels in Jamaica: a potential tool for identifying new genetic loci controlling fetal haemoglobin.

Authors:

Lisa E Creary Colin A McKenzie Stephan Menzel Neil A Hanchard Veronica Taylor Ian Hambleton Tim D Spector Terrence E Forrester Swee Lay Thein

Br J Haematol 2009 Mar 20;144(6):954-60. Epub 2008 Dec 20.

Division of Gene and Cell Based Therapy, King's College London School of Medicine, James Black Centre, London, UK.

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http://dx.doi.org/10.1111/j.1365-2141.2008.07532.x	DOI Listing

March 2009

5 Reads

2 Citations

4.711 Impact Factor

Genetic variation on chromosome 6 influences F cell levels in healthy individuals of African descent and HbF levels in sickle cell patients.

Authors:

Lisa E Creary Pinar Ulug Stephan Menzel Colin A McKenzie Neil A Hanchard Veronica Taylor Martin Farrall Terrence E Forrester Swee Lay Thein

PLoS One 2009 16;4(1):e4218. Epub 2009 Jan 16.

King's College London School of Medicine, Division of Gene and Cell, Based Therapy, James Black Centre, Denmark Hill Campus, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0004218	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621086	PMC

March 2009

9 Reads

28 Citations

3.234 Impact Factor

Hydroxyurea therapy lowers circulating DNA levels in sickle cell anemia.

Authors:

Pinar Ulug Nisha Vasavda Rohan Kumar Linda Keir Moji Awogbade Juliette Cunningham David C Rees Stephan Menzel Swee Lay Thein

Am J Hematol 2008 Sep;83(9):714-6

King's College London School of Medicine, Division of Gene and Cell Based Therapy, Denmark Hill Campus, London SE5 9NU.

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http://dx.doi.org/10.1002/ajh.21237	DOI Listing

September 2008

8 Reads

3 Citations

3.800 Impact Factor

The HBS1L-MYB intergenic region on chromosome 6q23.3 influences erythrocyte, platelet, and monocyte counts in humans.

Authors:

Stephan Menzel Jie Jiang Nicholas Silver Joy Gallagher Juliette Cunningham Gabriela Surdulescu Mark Lathrop Martin Farrall Tim D Spector Swee Lay Thein

Blood 2007 Nov 21;110(10):3624-6. Epub 2007 Aug 21.

King's College London School of Medicine, Division of Gene and Cell Based Therapy, London, United Kingdom.

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http://www.bloodjournal.org/content/110/10/3624.full.pdf	Web Search
http://www.bloodjournal.org/cgi/doi/10.1182/blood-2007-05-09	Publisher Site
http://dx.doi.org/10.1182/blood-2007-05-093419	DOI Listing

November 2007

15 Reads

29 Citations

10.452 Impact Factor

Circulating DNA: a potential marker of sickle cell crisis.

Authors:

Nisha Vasavda Pinar Ulug Sheila Kondaveeti Karthik Ramasamy Taku Sugai Gordon Cheung David C Rees Moji Awogbade Sybil Bannister Juliette Cunningham Stephan Menzel Swee Lay Thein

Br J Haematol 2007 Oct;139(2):331-6

King's College London, King's College Hospital, Division of Gene and Cell Based Therapy, Denmark Hill, London, UK.

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http://dx.doi.org/10.1111/j.1365-2141.2007.06775.x	DOI Listing

October 2007

29 Reads

3 Citations

4.711 Impact Factor

A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15.

Authors:

Stephan Menzel Chad Garner Ivo Gut Fumihiko Matsuda Masao Yamaguchi Simon Heath Mario Foglio Diana Zelenika Anne Boland Helen Rooks Steve Best Tim D Spector Martin Farrall Mark Lathrop Swee Lay Thein

Nat Genet 2007 Oct 2;39(10):1197-9. Epub 2007 Sep 2.

King's College London School of Medicine, Division of Gene and Cell Based Therapy, King's Denmark Hill Campus, London SE5 9PJ, UK.

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http://dx.doi.org/10.1038/ng2108	DOI Listing

October 2007

5 Reads

144 Citations

29.352 Impact Factor

The linear effects of alpha-thalassaemia, the UGT1A1 and HMOX1 polymorphisms on cholelithiasis in sickle cell disease.

Authors:

Nisha Vasavda Stephan Menzel Sheila Kondaveeti Emma Maytham Moji Awogbade Sybil Bannister Juliette Cunningham Andrew Eichholz Yvonne Daniel Iheanyi Okpala Tony Fulford Swee Lay Thein

Br J Haematol 2007 Jul;138(2):263-70

King's College London School of Medicine, Division of Gene and Cell Based Therapy, London, UK.

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http://dx.doi.org/10.1111/j.1365-2141.2007.06643.x	DOI Listing

July 2007

42 Reads

15 Citations

4.711 Impact Factor

Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults.

Authors:

Swee Lay Thein Stephan Menzel Xu Peng Steve Best Jie Jiang James Close Nicholas Silver Ageliki Gerovasilli Chen Ping Masao Yamaguchi Karin Wahlberg Pinar Ulug Tim D Spector Chad Garner Fumihiko Matsuda Martin Farrall Mark Lathrop

Proc Natl Acad Sci U S A 2007 Jul 25;104(27):11346-51. Epub 2007 Jun 25.

King's College London School of Medicine, Division of Gene and Cell Based Therapy, King's College Hospital, London SE5 9PJ, United Kingdom.

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http://dx.doi.org/10.1073/pnas.0611393104	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040901	PMC

July 2007

20 Reads

80 Citations

9.810 Impact Factor

cMYB is involved in the regulation of fetal hemoglobin production in adults.

Authors:

Jie Jiang Steve Best Stephan Menzel Nicholas Silver Mei I Lai Gabriela L Surdulescu Tim D Spector Swee Lay Thein

Blood 2006 Aug;108(3):1077-83

Department of Haematological Medicine, King's College London School of Medicine at King's College Hospital, Denmark Hill Campus, London SE5 9PJ, United Kingdom.

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