Stephan Brand

Stephan Brand

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Stephan Brand

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Contrast-enhanced ultrasound (CEUS) has excellent diagnostic accuracy in differentiating focal liver lesions: results from a Swiss tertiary gastroenterological centre.

Swiss Med Wkly 2019 Jun 30;149:w20087. Epub 2019 Jun 30.

Department of Gastroenterology and Hepatology, Kantonsspital St. Gallen, Switzerland.

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http://dx.doi.org/10.4414/smw.2019.20087DOI Listing
June 2019

Endoscopic Treatment of Early Barrett's Adenocarcinoma and Dysplasia: Focus on Submucosal Cancer.

Digestion 2019 3;99(4):293-300. Epub 2018 Sep 3.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kantonsspital Sankt Gallen, St. Gallen, Switzerland.

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http://dx.doi.org/10.1159/000492217DOI Listing
September 2018

Transcriptome-Wide High-Density Microarray Analysis Reveals Differential Gene Transcription in Periprosthetic Tissue From Hips With Chronic Periprosthetic Joint Infection vs Aseptic Loosening.

J Arthroplasty 2017 01 29;32(1):234-240. Epub 2016 Jun 29.

Department of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1016/j.arth.2016.06.036DOI Listing
January 2017

Injury severity of pedestrians, bicyclists and motorcyclists resulting from crashes with reversing cars.

Accid Anal Prev 2016 Sep 28;94:46-51. Epub 2016 May 28.

Trauma Department, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.aap.2016.05.010DOI Listing
September 2016

Effectiveness of Bicycle Safety Helmets in Preventing Facial Injuries in Road Accidents.

Arch Trauma Res 2016 Sep 29;5(3):e30011. Epub 2016 Jun 29.

Trauma Department, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.5812/atr.30011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079115PMC
September 2016

Impact of intraprosthetic drilling on the strength of the femoral stem in periprosthetic fractures: A finite element investigation.

Proc Inst Mech Eng H 2016 Jul 6;230(7):675-81. Epub 2016 May 6.

Institute of Materials Science, Leibniz University of Hannover, Hannover, Germany.

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http://dx.doi.org/10.1177/0954411916647078DOI Listing
July 2016

Open Repair Versus Thoracic Endovascular Aortic Repair in Multiple-Injured Patients: Observations From a Level-1 Trauma Center.

Arch Trauma Res 2015 Dec 5;4(4):e27183. Epub 2015 Dec 5.

Division of Vascular Surgery, Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.5812/atr.27183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733514PMC
December 2015

Lipocalin-2 Is a Disease Activity Marker in Inflammatory Bowel Disease Regulated by IL-17A, IL-22, and TNF-α and Modulated by IL23R Genotype Status.

Inflamm Bowel Dis 2015 Oct;21(10):2327-40

*Department of Medicine II, Grosshadern, Ludwig-Maximilians-Universität (LMU), Munich, Germany; †Clinic for Preventive Dentistry and Parodontology, LMU Munich, Munich, Germany; ‡Clinic for Pediatric Pneumology and Neonatology, Hannover Medical School, Hannover, Germany; §Department of Clinical Chemistry, Grosshadern, LMU Munich, Munich, Germany; and ‖Institute of Human Genetics, RWTH Aachen University, Aachen, Germany.

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http://dx.doi.org/10.1097/MIB.0000000000000515DOI Listing
October 2015

Concepts and Potential Future Developments for Treatment of Periprosthetic Proximal Femoral Fractures.

Open Orthop J 2015 31;9:405-11. Epub 2015 Aug 31.

Trauma Department, Hannover Medical School, Germany ; Steadman Philippon Research Institute, Vail, CO, USA.

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http://dx.doi.org/10.2174/1874325001509010405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578140PMC
September 2015

Current Concepts for Patellar Dislocation.

Arch Trauma Res 2015 Sep 1;4(3):e29301. Epub 2015 Sep 1.

Department of Trauma, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.5812/atr.29301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636822PMC
September 2015

[Medical therapy of ulcerative colitis].

Authors:
Stephan Brand

MMW Fortschr Med 2015 Feb;157(2):45-8

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http://link.springer.com/10.1007/s15006-015-2648-7
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http://dx.doi.org/10.1007/s15006-015-2648-7DOI Listing
February 2015

Colesevelam for the treatment of bile acid malabsorption-associated diarrhea in patients with Crohn's disease: a randomized, double-blind, placebo-controlled study.

J Crohns Colitis 2014 Nov 19;8(11):1471-9. Epub 2014 Jun 19.

Department of Medicine II, University Hospital Munich-Grosshadern, Ludwig-Maximilians-University Munich, Germany; Isarmedizin Zentrum, Munich, Germany.

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http://dx.doi.org/10.1016/j.crohns.2014.05.009DOI Listing
November 2014

IL-36γ sustains a proinflammatory self-amplifying loop with IL-17C in anti-TNF-induced psoriasiform skin lesions of patients with Crohn's disease.

Inflamm Bowel Dis 2014 Nov;20(11):1891-901

*Department of Medicine II, University-Hospital Munich-Grosshadern, Ludwig-Maximilians-University (LMU), Munich, Germany; †Clinic for Preventive Dentistry and Parodontology, Ludwig-Maximilians-University, Munich, Germany; and ‡Department of Dermatology and Allergy, Ludwig-Maximilians-University, Munich, Germany.

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http://dx.doi.org/10.1097/MIB.0000000000000198DOI Listing
November 2014

Thoracic injuries sustained by severely injured front-seat passengers and drivers: injury patterns and their relationship to crash characteristics.

Int J Inj Contr Saf Promot 2013 5;20(4):313-20. Epub 2012 Oct 5.

a Trauma Department , Medical School Hannover , Carl-Neuberg-Str. 1 , Hannover , 30625 , Germany.

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http://www.tandfonline.com/doi/abs/10.1080/17457300.2012.724
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http://dx.doi.org/10.1080/17457300.2012.724692DOI Listing
September 2014

Hybrid and electric low-noise cars cause an increase in traffic accidents involving vulnerable road users in urban areas.

Int J Inj Contr Saf Promot 2013 19;20(4):339-41. Epub 2012 Oct 19.

a Trauma Department , Hannover Medical School , MHH, with Accident Research Unit, Carl-Neuberg-Strasse 1/OE 6230, D-30625 , Hannover , Germany.

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http://www.tandfonline.com/doi/abs/10.1080/17457300.2012.733
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http://dx.doi.org/10.1080/17457300.2012.733714DOI Listing
September 2014

IL-17A alone weakly affects the transcriptome of intestinal epithelial cells but strongly modulates the TNF-α-induced expression of inflammatory mediators and inflammatory bowel disease susceptibility genes.

Inflamm Bowel Dis 2014 Sep;20(9):1502-15

*Department of Medicine II, and †Clinic for Preventive Dentistry and Parodontology, Ludwig-Maximilians-University, Munich, Germany.

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http://dx.doi.org/10.1097/MIB.0000000000000121DOI Listing
September 2014

Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2.

PLoS One 2013 5;8(11):e77773. Epub 2013 Nov 5.

Department of Medicine II - Grosshadern, Ludwig-Maximilians-University (LMU), Munich, Germany ; Department of Preventive Dentistry and Periodontology, Ludwig-Maximilians-University (LMU), Munich, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077773PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818382PMC
August 2014

Risk of malignancies in patients with inflammatory bowel disease treated with thiopurines or anti-TNF alpha antibodies.

Pharmacoepidemiol Drug Saf 2014 Jul 30;23(7):735-44. Epub 2014 Apr 30.

Department of Medicine II, University Hospital Munich-Grosshadern, Ludwig-Maximilians-University Munich, Munich, Germany.

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http://doi.wiley.com/10.1002/pds.3621
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http://dx.doi.org/10.1002/pds.3621DOI Listing
July 2014

Vertebral fractures in motor vehicle accidents - a medical and technical analysis of 33,015 injured front-seat occupants.

Accid Anal Prev 2014 May 15;66:15-9. Epub 2014 Jan 15.

Trauma Department and Accident Research Unit, Hannover Medical School (MHH), Carl-Neuberg-Strasse 1, D-30625 Hannover, Germany.

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http://dx.doi.org/10.1016/j.aap.2014.01.003DOI Listing
May 2014

What's new in emergencies, trauma and shock? studying traffic related injuries in India.

J Emerg Trauma Shock 2014 Apr;7(2):69-70

Department of Trauma, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.4103/0974-2700.130871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013738PMC
April 2014

Functional relevance of the cannabinoid receptor 2 - heme oxygenase pathway: a novel target for the attenuation of portal hypertension.

Life Sci 2013 Oct 3;93(16):543-51. Epub 2013 Sep 3.

Department of Medicine II (Gastroenterology and Hepatology), Liver Center Munich, University of Munich, Grosshadern, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.lfs.2013.08.018DOI Listing
October 2013

Response to Tsai et al.

Authors:
Stephan Brand

Am J Gastroenterol 2013 Sep;108(9):1536-7

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http://www.nature.com/articles/ajg2013216
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http://dx.doi.org/10.1038/ajg.2013.216DOI Listing
September 2013

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.

Nat Genet 2013 Jun 21;45(6):670-5. Epub 2013 Apr 21.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://petercroucher.com/wp-content/uploads/2013/10/51_Natur
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http://www.nature.com/doifinder/10.1038/ng.2616
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http://dx.doi.org/10.1038/ng.2616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667736PMC
June 2013

Bicyclist-bicyclist crashes--a medical and technical crash analysis.

Traffic Inj Prev 2013 ;14(1):56-60

Trauma Department, Hannover Medical School, Accident Research Unit, Hannover, Germany.

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http://dx.doi.org/10.1080/15389588.2012.688152DOI Listing
March 2013

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Authors:
Luke Jostins Stephan Ripke Rinse K Weersma Richard H Duerr Dermot P McGovern Ken Y Hui James C Lee L Philip Schumm Yashoda Sharma Carl A Anderson Jonah Essers Mitja Mitrovic Kaida Ning Isabelle Cleynen Emilie Theatre Sarah L Spain Soumya Raychaudhuri Philippe Goyette Zhi Wei Clara Abraham Jean-Paul Achkar Tariq Ahmad Leila Amininejad Ashwin N Ananthakrishnan Vibeke Andersen Jane M Andrews Leonard Baidoo Tobias Balschun Peter A Bampton Alain Bitton Gabrielle Boucher Stephan Brand Carsten Büning Ariella Cohain Sven Cichon Mauro D'Amato Dirk De Jong Kathy L Devaney Marla Dubinsky Cathryn Edwards David Ellinghaus Lynnette R Ferguson Denis Franchimont Karin Fransen Richard Gearry Michel Georges Christian Gieger Jürgen Glas Talin Haritunians Ailsa Hart Chris Hawkey Matija Hedl Xinli Hu Tom H Karlsen Limas Kupcinskas Subra Kugathasan Anna Latiano Debby Laukens Ian C Lawrance Charlie W Lees Edouard Louis Gillian Mahy John Mansfield Angharad R Morgan Craig Mowat William Newman Orazio Palmieri Cyriel Y Ponsioen Uros Potocnik Natalie J Prescott Miguel Regueiro Jerome I Rotter Richard K Russell Jeremy D Sanderson Miquel Sans Jack Satsangi Stefan Schreiber Lisa A Simms Jurgita Sventoraityte Stephan R Targan Kent D Taylor Mark Tremelling Hein W Verspaget Martine De Vos Cisca Wijmenga David C Wilson Juliane Winkelmann Ramnik J Xavier Sebastian Zeissig Bin Zhang Clarence K Zhang Hongyu Zhao Mark S Silverberg Vito Annese Hakon Hakonarson Steven R Brant Graham Radford-Smith Christopher G Mathew John D Rioux Eric E Schadt Mark J Daly Andre Franke Miles Parkes Severine Vermeire Jeffrey C Barrett Judy H Cho

Nature 2012 Nov;491(7422):119-24

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

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http://dx.doi.org/10.1038/nature11582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491803PMC
November 2012

Intraprosthetic fixation techniques in the treatment of periprosthetic fractures-A biomechanical study.

World J Orthop 2012 Oct;3(10):162-6

Stephan Brand, Maximilian Petri, Carl Haasper, Christian Krettek, Thomas Goesling, Department of Trauma, Medical School Hannover (MHH), D-30625 Hannover, Germany.

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http://dx.doi.org/10.5312/wjo.v3.i10.162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536858PMC
October 2012

Injury patterns of seniors in traffic accidents: A technical and medical analysis.

World J Orthop 2012 Sep;3(9):151-5

Stephan Brand, Dietmar Otte, Christian Walter Mueller, Maximilian Petri, Philipp Haas, Timo Stuebig, Timo Stuebig, Christian Krettek, Carl Haasper, Accident Research Unit, Trauma Department, Medical School Hannover (MHH), D-30625 Hannover, Germany.

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http://dx.doi.org/10.5312/wjo.v3.i9.151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502611PMC
September 2012

Infliximab does not affect postoperative complication rates in Crohn's patients undergoing abdominal surgery.

Inflamm Bowel Dis 2012 Jul 16;18(7):1207-13. Epub 2011 Sep 16.

Department of Surgery, Grosshadern, Ludwig-Maximilians-University Munich, Munich, Germany.

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http://dx.doi.org/10.1002/ibd.21860DOI Listing
July 2012

Perifosine-mediated Akt inhibition in neuroendocrine tumor cells: role of specific Akt isoforms.

Endocr Relat Cancer 2012 Jun 24;19(3):423-34. Epub 2012 May 24.

Department of Internal Medicine II, University-Hospital Munich-Grosshadern, Munich, Germany.

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http://dx.doi.org/10.1530/ERC-12-0074DOI Listing
June 2012

Homozygosity for the NOD2 p.Leu1007fsX1008 variant is the main genetic predictor for fibrostenotic Crohn's disease.

Authors:
Stephan Brand

Inflamm Bowel Dis 2012 Feb 29;18(2):393-4. Epub 2011 Oct 29.

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http://dx.doi.org/10.1002/ibd.21914DOI Listing
February 2012

Malignant melanoma during ustekinumab therapy of Crohn's disease.

Inflamm Bowel Dis 2012 Jan 10;18(1):E199-200. Epub 2011 Oct 10.

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http://dx.doi.org/10.1002/ibd.21877DOI Listing
January 2012

PSC: Protect and serve with colitis: does it help the liver to have severe ulcerative colitis?

Gut 2011 Sep 11;60(9):1165-6. Epub 2011 May 11.

Department of Medicine II, Klinikum Grosshadern, Ludwig-Maximilians-University, Marchioninistrasse 15, D-81377 Munich, Germany.

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http://dx.doi.org/10.1136/gut.2011.240309DOI Listing
September 2011

The novel Raf inhibitor Raf265 decreases Bcl-2 levels and confers TRAIL-sensitivity to neuroendocrine tumour cells.

Endocr Relat Cancer 2011 Apr 21;18(2):277-85. Epub 2011 Mar 21.

Department of Internal Medicine II, University-Hospital Munich-Grosshadern, University of Munich, Marchioninistr.15, 81377 Munich, Germany.

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http://dx.doi.org/10.1530/ERC-10-0108DOI Listing
April 2011

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

Authors:
Carl A Anderson Gabrielle Boucher Charlie W Lees Andre Franke Mauro D'Amato Kent D Taylor James C Lee Philippe Goyette Marcin Imielinski Anna Latiano Caroline Lagacé Regan Scott Leila Amininejad Suzannah Bumpstead Leonard Baidoo Robert N Baldassano Murray Barclay Theodore M Bayless Stephan Brand Carsten Büning Jean-Frédéric Colombel Lee A Denson Martine De Vos Marla Dubinsky Cathryn Edwards David Ellinghaus Rudolf S N Fehrmann James A B Floyd Timothy Florin Denis Franchimont Lude Franke Michel Georges Jürgen Glas Nicole L Glazer Stephen L Guthery Talin Haritunians Nicholas K Hayward Jean-Pierre Hugot Gilles Jobin Debby Laukens Ian Lawrance Marc Lémann Arie Levine Cecile Libioulle Edouard Louis Dermot P McGovern Monica Milla Grant W Montgomery Katherine I Morley Craig Mowat Aylwin Ng William Newman Roel A Ophoff Laura Papi Orazio Palmieri Laurent Peyrin-Biroulet Julián Panés Anne Phillips Natalie J Prescott Deborah D Proctor Rebecca Roberts Richard Russell Paul Rutgeerts Jeremy Sanderson Miquel Sans Philip Schumm Frank Seibold Yashoda Sharma Lisa A Simms Mark Seielstad A Hillary Steinhart Stephan R Targan Leonard H van den Berg Morten Vatn Hein Verspaget Thomas Walters Cisca Wijmenga David C Wilson Harm-Jan Westra Ramnik J Xavier Zhen Z Zhao Cyriel Y Ponsioen Vibeke Andersen Leif Torkvist Maria Gazouli Nicholas P Anagnou Tom H Karlsen Limas Kupcinskas Jurgita Sventoraityte John C Mansfield Subra Kugathasan Mark S Silverberg Jonas Halfvarson Jerome I Rotter Christopher G Mathew Anne M Griffiths Richard Gearry Tariq Ahmad Steven R Brant Mathias Chamaillard Jack Satsangi Judy H Cho Stefan Schreiber Mark J Daly Jeffrey C Barrett Miles Parkes Vito Annese Hakon Hakonarson Graham Radford-Smith Richard H Duerr Séverine Vermeire Rinse K Weersma John D Rioux

Nat Genet 2011 Mar 6;43(3):246-52. Epub 2011 Feb 6.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084597PMC
March 2011

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.

Nat Genet 2010 Dec;42(12):1118-25

Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Kiel, Germany.

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http://dx.doi.org/10.1038/ng.717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299551PMC
December 2010

Compensatory activation of Akt in response to mTOR and Raf inhibitors - a rationale for dual-targeted therapy approaches in neuroendocrine tumor disease.

Cancer Lett 2010 Sep 30;295(1):100-9. Epub 2010 Mar 30.

Department of Internal Medicine II, University-Hospital Munich-Grosshadern, University of Munich, Marchioninistr.15, 81377 Munich, Germany.

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http://dx.doi.org/10.1016/j.canlet.2010.02.018DOI Listing
September 2010

Severe Legionella pneumophila pneumonia following infliximab therapy in a patient with Crohn's disease.

Inflamm Bowel Dis 2009 Aug;15(8):1240-4

Department of Medicine II, University Hospital Munich-Grosshadern, Ludwig-Maximilians-University Munich, Germany.

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http://dx.doi.org/10.1002/ibd.20866DOI Listing
August 2009

Effects of the cathelicidin LL-37 on intestinal epithelial barrier integrity.

Regul Pept 2009 Aug 26;156(1-3):104-17. Epub 2009 Mar 26.

Department of Internal Medicine I, St. Josef-Hospital, Ruhr-University, Bochum, Germany.

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http://dx.doi.org/10.1016/j.regpep.2009.03.009DOI Listing
August 2009

Hepatosplenic T-cell lymphoma in a patient with Crohn's disease.

Nat Rev Gastroenterol Hepatol 2009 Jul;6(7):433-6

Department of Medicine II, University Hospital, Munich-Grosshadern, Munich, Germany.

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http://dx.doi.org/10.1038/nrgastro.2009.87DOI Listing
July 2009

Probiotics regulate the expression of COX-2 in intestinal epithelial cells.

Nutr Cancer 2009 ;61(1):103-13

Department of Internal Medicine I, St. Josef-Hospital, Ruhr-University, Bochum, Germany.

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http://dx.doi.org/10.1080/01635580802372625DOI Listing
April 2009

IL-22: a two-headed cytokine in IBD?

Inflamm Bowel Dis 2009 Mar;15(3):473-4

Department of Medicine II, Ludwig-Maximilians-University Munich, Grosshadern, Munich, Germany.

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https://academic.oup.com/ibdjournal/article/15/3/473-474/464
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http://dx.doi.org/10.1002/ibd.20625DOI Listing
March 2009

Targeting endocannabinoid degradation protects against experimental colitis in mice: involvement of CB1 and CB2 receptors.

J Mol Med (Berl) 2008 Aug 21;86(8):925-36. Epub 2008 May 21.

Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1007/s00109-008-0359-6DOI Listing
August 2008

Free fatty acids sensitize hepatocytes to bile acid-induced apoptosis.

Biochem Biophys Res Commun 2008 Jul 29;371(3):441-5. Epub 2008 Apr 29.

Department of Medicine II-Grosshadern, University of Munich, Marchioninistrasse 15, 81377 Munich, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2008.04.113DOI Listing
July 2008