Sten Eirik Jacobsen

Sten Eirik Jacobsen

UNVERIFIED PROFILE

Are you Sten Eirik Jacobsen?   Register this Author

Register author
Sten Eirik Jacobsen

Sten Eirik Jacobsen

Publications by authors named "Sten Eirik Jacobsen"

Are you Sten Eirik Jacobsen?   Register this Author

100Publications

2214Reads

12Profile Views

Unravelling Intratumoral Heterogeneity through High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing.

Mol Cell 2019 03 12;73(6):1292-1305.e8. Epub 2019 Feb 12.

Haematopoietic Stem Cell Biology Laboratory, Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK; Medical Research Council Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK; National Institute for Health Research Biomedical Research Centre, University of Oxford, Oxford, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2019.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436961PMC
March 2019

Haematopoiesis in the era of advanced single-cell technologies.

Nat Cell Biol 2019 01 2;21(1):2-8. Epub 2019 Jan 2.

MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41556-018-0227-8DOI Listing
January 2019

Loss of Canonical Notch Signaling Affects Multiple Steps in NK Cell Development in Mice.

J Immunol 2018 12 26;201(11):3307-3319. Epub 2018 Oct 26.

Lund Research Center for Stem Cell Biology and Cell Therapy, Lund University, 221 84 Lund, Sweden;

View Article

Download full-text PDF

Source
http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1701675
Publisher Site
http://dx.doi.org/10.4049/jimmunol.1701675DOI Listing
December 2018

Origins of ETP leukemia.

Oncoscience 2018 Nov 22;5(11-12):271-272. Epub 2018 Aug 22.

MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, OX3 9DS UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncoscience.456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326737PMC
November 2018

Kit ligand has a critical role in mouse yolk sac and aorta-gonad-mesonephros hematopoiesis.

EMBO Rep 2018 10 30;19(10). Epub 2018 Aug 30.

MRC Molecular Hematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/embr.201745477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172468PMC
October 2018

Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells.

Nature 2018 02 3;554(7690):106-111. Epub 2018 Jan 3.

Haematopoietic Stem Cell Laboratory, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DS, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature25455DOI Listing
February 2018

Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors.

Cancer Cell 2018 02;33(2):274-291.e8

Haematopoietic Stem Cell Biology Laboratory, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DS, UK; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DS, UK; NIHR Biomedical Research Centre, Churchill Hospital, Oxford OX3 7LE, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2018.01.006DOI Listing
February 2018

Autophagy-Dependent Generation of Free Fatty Acids Is Critical for Normal Neutrophil Differentiation.

Immunity 2017 09 12;47(3):466-480.e5. Epub 2017 Sep 12.

Kennedy Institute of Rheumatology, University of Oxford, Roosevelt Drive, Oxford OX3 7FY, UK; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DS, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2017.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610174PMC
September 2017

-initiating mutations in MDS-RSs target lymphomyeloid hematopoietic stem cells.

Blood 2017 08 20;130(7):881-890. Epub 2017 Jun 20.

Center for Hematology and Regenerative Medicine, Karolinska Institutet, Department of Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2017-03-776070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572789PMC
August 2017

Macrophage colony-stimulating factor receptor marks and regulates a fetal myeloid-primed B-cell progenitor in mice.

Blood 2016 07 17;128(2):217-26. Epub 2016 May 17.

Lund Research Center for Stem Cell Biology and Cell Therapy, Division of Molecular Hematology, Department of Laboratory Medicine.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2016-01-693887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009960PMC
July 2016

Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development.

Cell Rep 2016 07 7;16(4):1039-1054. Epub 2016 Jul 7.

Department of Haematology, Cambridge Institute for Medical Research, Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge CB2 0XY, UK; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4UU, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2016.06.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967476PMC
July 2016

Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells.

Nat Commun 2016 Mar 24;7:11075. Epub 2016 Mar 24.

MRC Molecular Hematology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms11075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820843PMC
March 2016

Autophagy limits proliferation and glycolytic metabolism in acute myeloid leukemia.

Cell Death Discov 2015 Aug;1

Translational Immunology Lab, BRC- NIHR, John Radcliffe Hospital, Experimental Medicine, Nuffield Department of Medicine, Oxford OX3 9DU, UK ; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford OX3 9DS, UK.

View Article

Download full-text PDF

Source
http://search.proquest.com/openview/620e53d7bdb55fb4e8cad3e6
Web Search
http://www.nature.com/articles/cddiscovery20158
Publisher Site
http://dx.doi.org/10.1038/cddiscovery.2015.8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641322PMC
August 2015

A pilot phase I dose finding safety study of the thrombopoietin-receptor agonist, eltrombopag, in patients with myelodysplastic syndrome treated with azacitidine.

Eur J Haematol 2014 Nov 14;93(5):439-45. Epub 2014 Jun 14.

Department of Medical Sciences, Section of Hematology, Uppsala University Hospital, Uppsala, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ejh.12383DOI Listing
November 2014

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.

Cancer Cell 2014 Jun 15;25(6):794-808. Epub 2014 May 15.

Haematopoietic Stem Cell Biology Laboratory, MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK; Departments of Cell and Molecular Biology, Medicine Huddinge, and Laboratory Medicine, Huddinge, Karolinska Institutet and Center for Hematology and Regenerative Medicine, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccr.2014.03.036DOI Listing
June 2014

Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate.

J Exp Med 2014 Feb 3;211(2):181-8. Epub 2014 Feb 3.

Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, England, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20131189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920567PMC
February 2014

Germline counterparts of oncogenic mutations: who gives a JAK?.

Oncotarget 2013 Jun;4(6):814-5

Haematopoietic Stem Cell Biology Laboratory, WIMM, University of Oxford, Oxford, UK .

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757239PMC
http://dx.doi.org/10.18632/oncotarget.1105DOI Listing
June 2013

Impact of isolated germline JAK2V617I mutation on human hematopoiesis.

Blood 2013 May 27;121(20):4156-65. Epub 2013 Mar 27.

Haematopoietic Stem Cell Biology Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2012-05-430926DOI Listing
May 2013

Characterization of transcriptional networks in blood stem and progenitor cells using high-throughput single-cell gene expression analysis.

Nat Cell Biol 2013 Apr 24;15(4):363-72. Epub 2013 Mar 24.

Department of Haematology, Wellcome Trust and MRC Cambridge Stem Cell Institute and Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncb2709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796878PMC
April 2013

Dicer is selectively important for the earliest stages of erythroid development.

Blood 2012 Sep 6;120(12):2412-6. Epub 2012 Aug 6.

Haematopoietic Stem Cell Laboratory, MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2011-10-383653DOI Listing
September 2012

Emergence of NK-cell progenitors and functionally competent NK-cell lineage subsets in the early mouse embryo.

Blood 2012 Jul 9;120(1):63-75. Epub 2011 Nov 9.

Hematopoietic Stem Cell Laboratory, Lund Research Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2011-02-337980DOI Listing
July 2012

A lineage of myeloid cells independent of Myb and hematopoietic stem cells.

Science 2012 Apr 22;336(6077):86-90. Epub 2012 Mar 22.

Centre for Molecular and Cellular Biology of Inflammation, New Hunt's House, King's College London, Great Maze Pond, London SE1 1UL, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1219179DOI Listing
April 2012

Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1.

PLoS Genet 2011 Dec 22;7(12):e1002404. Epub 2011 Dec 22.

Medical Research Council Human Genetics Unit and the Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1002404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245305PMC
December 2011

FLT3 expression initiates in fully multipotent mouse hematopoietic progenitor cells.

Blood 2011 Aug 31;118(6):1544-8. Epub 2011 May 31.

Haematopoietic Stem Cell Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2010-10-316232DOI Listing
August 2011

GATA3 is redundant for maintenance and self-renewal of hematopoietic stem cells.

Blood 2011 Aug 13;118(5):1291-3. Epub 2011 Jun 13.

Haematopoietic Stem Cell Laboratory, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2011-02-338046DOI Listing
August 2011

Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors.

J Exp Med 2011 Aug 18;208(8):1563-70. Epub 2011 Jul 18.

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, 221 84 Lund, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20110752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149225PMC
August 2011

Hoxb4-YFP reporter mouse model: a novel tool for tracking HSC development and studying the role of Hoxb4 in hematopoiesis.

Blood 2011 Mar 28;117(13):3521-8. Epub 2011 Jan 28.

Ontogeny of Haematopoietic Stem Cells Group, Medical Research Council/Juvenile Diabetes Research Foundation Centre for Development in Stem Cell Biology, Institute for Stem Cell Research, University of Edinburgh, West Mains Road, Edinburgh, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2009-12-253989DOI Listing
March 2011

Clever leukemic stem cells branch out.

Cell Stem Cell 2011 Mar;8(3):242-4

MRC Molecular Haematology Unit, Radcliffe Hospital, Oxford OX3 9DU, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2011.02.015DOI Listing
March 2011

Identification of an NK/T cell-restricted progenitor in adult bone marrow contributing to bone marrow- and thymic-dependent NK cells.

Blood 2010 Jul 26;116(2):183-92. Epub 2010 Apr 26.

Hematopoietic Stem Cell Laboratory, Lund Research Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2009-10-247130DOI Listing
July 2010

Developmental biology: Instructions writ in blood.

Nature 2009 Sep;461(7261):183-4

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/461183aDOI Listing
September 2009

Long-term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke.

Glia 2009 Jun;57(8):835-49

Laboratory of Neurogenesis and Cell Therapy, Section of Restorative Neurology, Wallenberg Neuroscience Center A11, University Hospital, Lund, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/glia.20810DOI Listing
June 2009

Polyclonal T-cell reconstitution of X-SCID recipients after in utero transplantation of lymphoid-primed multipotent progenitors.

Blood 2009 May 12;113(19):4790-8. Epub 2008 Dec 12.

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell, Biology and Cell Therapy, Lund University, Lund, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2007-12-129056DOI Listing
May 2009

FLT3 receptor and ligand are dispensable for maintenance and posttransplantation expansion of mouse hematopoietic stem cells.

Blood 2009 Apr 2;113(15):3453-60. Epub 2009 Feb 2.

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2008-08-174060DOI Listing
April 2009

High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle.

Blood 2009 Mar 23;113(12):2661-72. Epub 2009 Jan 23.

Medical Research Council Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2008-06-161117DOI Listing
March 2009

Distinct and overlapping patterns of cytokine regulation of thymic and bone marrow-derived NK cell development.

J Immunol 2009 Feb;182(3):1460-8

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.182.3.1460DOI Listing
February 2009

FLT3 ligand and not TSLP is the key regulator of IL-7-independent B-1 and B-2 B lymphopoiesis.

Blood 2008 Sep 19;112(6):2297-304. Epub 2008 Jun 19.

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2008-04-150508DOI Listing
September 2008

B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells.

Blood 2008 Aug 21;112(4):1048-55. Epub 2008 May 21.

Department for Biomedicine and Surgery, Linköping University, Linköping, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2007-11-125385DOI Listing
August 2008

Delineating the cellular pathways of hematopoietic lineage commitment.

Semin Immunol 2008 Aug 27;20(4):213-20. Epub 2008 Aug 27.

Haematopoietic Stem Cell Laboratory, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.smim.2008.07.005DOI Listing
August 2008

Down-regulation of Mpl marks the transition to lymphoid-primed multipotent progenitors with gradual loss of granulocyte-monocyte potential.

Blood 2008 Apr 24;111(7):3424-34. Epub 2008 Jan 24.

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2007-08-108324DOI Listing
April 2008

Permissive roles of hematopoietin and cytokine tyrosine kinase receptors in early T-cell development.

Blood 2008 Feb 26;111(4):2083-90. Epub 2007 Nov 26.

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2007-08-108563DOI Listing
February 2008

Kit regulates maintenance of quiescent hematopoietic stem cells.

J Immunol 2008 Feb;180(4):2045-53

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.180.4.2045DOI Listing
February 2008

Protein kinase B (c-akt) regulates hematopoietic lineage choice decisions during myelopoiesis.

Blood 2008 Jan 21;111(1):112-21. Epub 2007 Sep 21.

Molecular Immunology Lab, Department of Immunology, University Medical Center, Utrecht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2006-07-037572DOI Listing
January 2008

Involvement of CCR9 at multiple stages of adult T lymphopoiesis.

J Leukoc Biol 2008 Jan 2;83(1):156-64. Epub 2007 Oct 2.

Immunolology Section, Lund University, BMCI13, Lund, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.0607423DOI Listing
January 2008

Critical role of thrombopoietin in maintaining adult quiescent hematopoietic stem cells.

Cell Stem Cell 2007 Dec 20;1(6):671-84. Epub 2007 Nov 20.

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, 221 84, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2007.10.008DOI Listing
December 2007

Distinct roles of integrins alpha6 and alpha4 in homing of fetal liver hematopoietic stem and progenitor cells.

Blood 2007 Oct 22;110(7):2399-407. Epub 2007 Jun 22.

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden.

View Article

Download full-text PDF

Source
http://www.bloodjournal.org/cgi/doi/10.1182/blood-2006-10-05
Publisher Site
http://dx.doi.org/10.1182/blood-2006-10-051276DOI Listing
October 2007

TSLP-mediated fetal B lymphopoiesis?

Nat Immunol 2007 Sep;8(9):897; author reply 898

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ni0907-897DOI Listing
September 2007

Crucial role of FLT3 ligand in immune reconstitution after bone marrow transplantation and high-dose chemotherapy.

Blood 2007 Jul 22;110(1):424-32. Epub 2007 Mar 22.

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2006-09-047480DOI Listing
July 2007

Delineation of the earliest lineage commitment steps of haematopoietic stem cells: new developments, controversies and major challenges.

Curr Opin Hematol 2007 Jul;14(4):315-21

Haematopoietic Stem Cell Laboratory, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Headington, Oxford, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MOH.0b013e3281de72bbDOI Listing
July 2007

Biological and molecular evidence for existence of lymphoid-primed multipotent progenitors.

Ann N Y Acad Sci 2007 Jun 18;1106:89-94. Epub 2007 Apr 18.

Haematopoietic Stem Cell Laboratory, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Headington, Oxford, OX3 9DS, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1196/annals.1392.023DOI Listing
June 2007

Ectopic expression of PAX5 promotes maintenance of biphenotypic myeloid progenitors coexpressing myeloid and B-cell lineage-associated genes.

Blood 2007 May 11;109(9):3697-705. Epub 2007 Jan 11.

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, Klinikgatan 26, 221 84 Lund, Sweden.

View Article

Download full-text PDF

Source
http://www.bloodjournal.org/cgi/doi/10.1182/blood-2006-05-02
Publisher Site
http://dx.doi.org/10.1182/blood-2006-05-026021DOI Listing
May 2007

Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.

Nat Immunol 2006 Oct 3;7(10):1048-56. Epub 2006 Sep 3.

European Molecular Biology Laboratory Mouse Biology Unit, 00016 Monterotondo, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ni1381DOI Listing
October 2006

Tumor necrosis factor receptor 1 is a negative regulator of progenitor proliferation in adult hippocampal neurogenesis.

J Neurosci 2006 Sep;26(38):9703-12

Laboratory of Neurogenesis and Cell Therapy, Section of Restorative Neurology, Wallenberg Neuroscience Center, University Hospital, SE 221 84 Lund, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1523/JNEUROSCI.2723-06.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6674454PMC
September 2006

Prolonged cell cycle transit is a defining and developmentally conserved hemopoietic stem cell property.

J Immunol 2006 Jul;177(1):201-8

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.177.1.201DOI Listing
July 2006

Failure of transdifferentiation of adult hematopoietic stem cells into neurons.

Stem Cells 2006 Jun 23;24(6):1594-604. Epub 2006 Mar 23.

Neuronal Survival Unit, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1634/stemcells.2005-0548DOI Listing
June 2006

Failure of transplanted bone marrow cells to adopt a pancreatic beta-cell fate.

Diabetes 2006 Feb;55(2):290-6

Hematopoietic Stem Cell Laboratory, Lund University, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/diabetes.55.02.06.db05-1212DOI Listing
February 2006