Steffi Oesterreich

Steffi Oesterreich

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Steffi Oesterreich

Publications by authors named "Steffi Oesterreich"

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Frequent amplifications of ESR1, ERBB2 and MDM4 in primary invasive lobular breast carcinoma.

Cancer Lett 2019 Oct 20;461:21-30. Epub 2019 Jun 20.

Women's Cancer Research Center, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA; UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Department of Pharmacology and Chemical Biology; University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.canlet.2019.06.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682463PMC
October 2019

SNAIL is induced by tamoxifen and leads to growth inhibition in invasive lobular breast carcinoma.

Breast Cancer Res Treat 2019 Jun 23;175(2):327-337. Epub 2019 Feb 23.

Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15261, USA.

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http://dx.doi.org/10.1007/s10549-019-05161-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625318PMC
June 2019

Targeted mutation detection in breast cancer using MammaSeq™.

Breast Cancer Res 2019 02 8;21(1):22. Epub 2019 Feb 8.

Department of Pharmacology and Chemical Biology, and Human Genetics, UPMC Hillman Cancer Center, Magee-Womens Research Institute, University of Pittsburgh, 204 Craft Avenue, Pittsburgh, PA, 15213, USA.

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https://breast-cancer-research.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s13058-019-1102-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368740PMC
February 2019

Network-guided prediction of aromatase inhibitor response in breast cancer.

PLoS Comput Biol 2019 02 11;15(2):e1006730. Epub 2019 Feb 11.

Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1006730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386390PMC
February 2019

Comprehensive Phenotypic Characterization of Human Invasive Lobular Carcinoma Cell Lines in 2D and 3D Cultures.

Cancer Res 2018 11 18;78(21):6209-6222. Epub 2018 Sep 18.

Women's Cancer Research Center, University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center (HCC), Magee-Womens Research Institute, Pittsburgh, Pennsylvania.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-18-1416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507416PMC
November 2018

Loss of E-cadherin Enhances IGF1-IGF1R Pathway Activation and Sensitizes Breast Cancers to Anti-IGF1R/InsR Inhibitors.

Clin Cancer Res 2018 10 25;24(20):5165-5177. Epub 2018 Jun 25.

Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-0279DOI Listing
October 2018

HDAC5-LSD1 axis regulates antineoplastic effect of natural HDAC inhibitor sulforaphane in human breast cancer cells.

Int J Cancer 2018 09 20;143(6):1388-1401. Epub 2018 Apr 20.

Women's Cancer Research Center, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://doi.wiley.com/10.1002/ijc.31419
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http://dx.doi.org/10.1002/ijc.31419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105499PMC
September 2018

Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer.

Breast Cancer Res 2018 09 4;20(1):106. Epub 2018 Sep 4.

Women's Cancer Research Center, UPMC Hillman Cancer Institute, Magee Womens Research Institute, 204 Craft Avenue, Pittsburgh, PA, 15213, USA.

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https://breast-cancer-research.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s13058-018-1041-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124012PMC
September 2018

Heterogeneity in Metastatic Breast Cancer F-Fluoroestradiol Uptake: Clinically Actionable, Biologically Illuminating?

J Nucl Med 2018 08 14;59(8):1210-1211. Epub 2018 Jun 14.

UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania; and.

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http://dx.doi.org/10.2967/jnumed.118.214304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071507PMC
August 2018

Opening the Door for Immune Oncology Studies in Invasive Lobular Breast Cancer.

J Natl Cancer Inst 2018 07;110(7):696-698

Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA.

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http://dx.doi.org/10.1093/jnci/djy014DOI Listing
July 2018

Invasive lobular and ductal breast carcinoma differ in immune response, protein translation efficiency and metabolism.

Sci Rep 2018 05 8;8(1):7205. Epub 2018 May 8.

Womens Cancer Research Center, UPMC Hillman Cancer Center, Magee Womens Research Institute, Pittsburgh, PA, 15213, USA.

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http://dx.doi.org/10.1038/s41598-018-25357-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940770PMC
May 2018

Precision Medicine in Hormone Receptor-Positive Breast Cancer.

Front Oncol 2018 4;8:144. Epub 2018 May 4.

Women's Cancer Research Center, Department of Pharmacology and Chemical Biology, UPMC Hillman Cancer Center, Magee Womens Research Institute, Pittsburgh, PA, United States.

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http://journal.frontiersin.org/article/10.3389/fonc.2018.001
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http://dx.doi.org/10.3389/fonc.2018.00144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945817PMC
May 2018

A Peroxidase Peroxiredoxin 1-Specific Redox Regulation of the Novel FOXO3 microRNA Target let-7.

Antioxid Redox Signal 2018 Jan 1;28(1):62-77. Epub 2017 May 1.

2 Department of Pharmacology and Chemical Biology, Magee Womens Research Institute, University of Pittsburgh Cancer Institute , Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1089/ars.2016.6871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695745PMC
January 2018

Upregulation of IRS1 Enhances IGF1 Response in Y537S and D538G ESR1 Mutant Breast Cancer Cells.

Endocrinology 2018 01;159(1):285-296

Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1210/en.2017-00693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761602PMC
January 2018

Determinants of prolactin in postmenopausal Chinese women in Singapore.

Cancer Causes Control 2018 01 9;29(1):51-62. Epub 2017 Nov 9.

Cancer Control and Population Sciences, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1007/s10552-017-0978-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962355PMC
January 2018

Functional characterization of lysine-specific demethylase 2 (LSD2/KDM1B) in breast cancer progression.

Oncotarget 2017 Oct 19;8(47):81737-81753. Epub 2017 Jul 19.

Women's Cancer Research Center, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.18632/oncotarget.19387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669845PMC
October 2017

A Joint Bayesian Model for Integrating Microarray and RNA Sequencing Transcriptomic Data.

J Comput Biol 2017 Jul 25;24(7):647-662. Epub 2017 May 25.

1 Department of Biostatistics, University of Pittsburgh , Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1089/cmb.2017.0056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510692PMC
July 2017

Estradiol as a Targeted, Late-Line Therapy in Metastatic Breast Cancer with Estrogen Receptor Amplification.

Cureus 2017 Jul 6;9(7):e1434. Epub 2017 Jul 6.

Pharmacology and Chemical Biology, University Of Pittsburgh.

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http://dx.doi.org/10.7759/cureus.1434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587405PMC
July 2017

Intrinsic Subtype Switching and Acquired ERBB2/HER2 Amplifications and Mutations in Breast Cancer Brain Metastases.

JAMA Oncol 2017 May;3(5):666-671

Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania2Women's Cancer Research Center, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania3Magee-Women's Research Institute, Magee-Women's Research Hospital of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania7Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1001/jamaoncol.2016.5630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508875PMC
May 2017

MetaDCN: meta-analysis framework for differential co-expression network detection with an application in breast cancer.

Bioinformatics 2017 Apr;33(8):1121-1129

Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1093/bioinformatics/btw788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041767PMC
April 2017

Integrative clustering of multi-level omics data for disease subtype discovery using sequential double regularization.

Biostatistics 2017 01 22;18(1):165-179. Epub 2016 Aug 22.

Department of Biostatistics, University of Pittsburgh, 130 Desoto Street, Pittsburgh, PA 15261, USA

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http://dx.doi.org/10.1093/biostatistics/kxw039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5255053PMC
January 2017

Intratumor Heterogeneity Affects Gene Expression Profile Test Prognostic Risk Stratification in Early Breast Cancer.

Clin Cancer Res 2016 Nov 16;22(21):5362-5369. Epub 2016 May 16.

Women's Cancer Research Center, Department of Pharmacology and Chemical Biology, University of Pittsburgh Cancer Institute, Magee Womens Research Institute, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093028PMC
November 2016

Epigenomic Deconvolution of Breast Tumors Reveals Metabolic Coupling between Constituent Cell Types.

Cell Rep 2016 11;17(8):2075-2086

Molecular and Human Genetics Department, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA; Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.10.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115176PMC
November 2016

Endocrine Response Phenotypes Are Altered by Charcoal-Stripped Serum Variability.

Endocrinology 2016 Oct 26;157(10):3760-3766. Epub 2016 Jul 26.

Women's Cancer Research Center (M.J.S., A.V.L., S.O.) and Department of Pharmacology and Chemical Biology (M.J.S., A.V.L., S.O.), University of Pittsburgh, Pittsburgh, Pennsylvania 15213; and Department of Oncology (M.D.J.), Georgetown University Lombardi Comprehensive Cancer Center, Georgetown University, Washington, D.C. 20057.

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http://dx.doi.org/10.1210/en.2016-1297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045515PMC
October 2016

Three-Dimensional Breast Cancer Models Mimic Hallmarks of Size-Induced Tumor Progression.

Cancer Res 2016 07 23;76(13):3732-43. Epub 2016 May 23.

Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania. Department of Bioengineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania. McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-2304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947371PMC
July 2016

High expression of orphan nuclear receptor NR4A1 in a subset of ovarian tumors with worse outcome.

Gynecol Oncol 2016 05 11;141(2):348-356. Epub 2016 Mar 11.

Department of Pharmacology and Chemical Biology, Womens Cancer Research Center, Magee-Womens Research Institute, and University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.ygyno.2016.02.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154956PMC
May 2016

Meta-analytic framework for sparse -means to identify disease subtypes in multiple transcriptomic studies.

J Am Stat Assoc 2016 5;111(513):27-42. Epub 2016 May 5.

Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA 15261,

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http://dx.doi.org/10.1080/01621459.2015.1086354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908837PMC
May 2016

A Role for Histone H2B Variants in Endocrine-Resistant Breast Cancer.

Horm Cancer 2015 Dec 26;6(5-6):214-24. Epub 2015 Jun 26.

Department of Pharmacology and Chemical Biology, Women's Cancer Research Center (WCRC), Magee-Womens Research Institute (MWRI), University of Pittsburgh Cancer Institute (UPCI), 204 Craft Avenue, Pittsburgh, PA, 15213, USA.

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http://dx.doi.org/10.1007/s12672-015-0230-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807402PMC
December 2015

Treating gynecologic malignancies with selective estrogen receptor downregulators (SERDs): promise and challenges.

Mol Cell Endocrinol 2015 Dec 11;418 Pt 3:322-33. Epub 2015 Aug 11.

University of Pittsburgh Cancer Institute, Department of Pharmacology and Chemical Biology, Women's Cancer Research Center, Magee-Womens Research Institute, Pittsburgh, PA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S03037207153003
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http://dx.doi.org/10.1016/j.mce.2015.04.035DOI Listing
December 2015

The estrogen receptor alpha nuclear localization sequence is critical for fulvestrant-induced degradation of the receptor.

Mol Cell Endocrinol 2015 Nov 10;415:76-86. Epub 2015 Aug 10.

Women's Cancer Research Center, Magee Women's Research Institute, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA; Department of Pharmacology and Chemical Biology, Magee Women's Research Institute, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2015.08.007DOI Listing
November 2015

Scaffold attachment factor B2 (SAFB2)-null mice reveal non-redundant functions of SAFB2 compared with its paralog, SAFB1.

Dis Model Mech 2015 Sep 18;8(9):1121-7. Epub 2015 Jun 18.

Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA Lester and Sue Smith Breast Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA

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http://dx.doi.org/10.1242/dmm.019885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582101PMC
September 2015

Developing in vitro models of human ductal carcinoma in situ from primary tissue explants.

Breast Cancer Res Treat 2015 Sep 18;153(2):311-21. Epub 2015 Aug 18.

Division of Surgical Oncology, Department of Surgery, University of Pittsburgh School of Medicine, 300 Halket Street, Suite 2601, Pittsburgh, PA, 15217, USA.

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http://dx.doi.org/10.1007/s10549-015-3551-8DOI Listing
September 2015

MCF-7 cells--changing the course of breast cancer research and care for 45 years.

J Natl Cancer Inst 2015 Jul 31;107(7). Epub 2015 Mar 31.

Departments of Pharmacology and Chemical Biology, Human Genetics, and Medicine, Women's Cancer Research Center, Magee-Womens Research Institute, University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA (AVL, SO, NED); University of Pittsburgh Cancer Institute and UPMC Cancer Center, 5150 Center Avenue, Pittsburgh, PA (NED).

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https://academic.oup.com/jnci/article-lookup/doi/10.1093/jnc
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http://dx.doi.org/10.1093/jnci/djv073DOI Listing
July 2015

Molecular drivers of lobular carcinoma in situ.

Breast Cancer Res 2015 Jun 4;17:76. Epub 2015 Jun 4.

Womens Cancer Research Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA, 15213, USA.

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http://dx.doi.org/10.1186/s13058-015-0580-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453073PMC
June 2015

Bias correction for selecting the minimal-error classifier from many machine learning models.

Bioinformatics 2014 Nov 1;30(22):3152-8. Epub 2014 Aug 1.

Joint Carnegie Mellon University-University of Pittsburgh Ph.D. Program in Computational Biology, Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA and Magee-Womens Research Institute, Pittsburgh, PA 15213, USA Joint Carnegie Mellon University-University of Pittsburgh Ph.D. Program in Computational Biology, Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA and Magee-Womens Research Institute, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1093/bioinformatics/btu520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221122PMC
November 2014

Inhibition of histone demethylase, LSD2 (KDM1B), attenuates DNA methylation and increases sensitivity to DNMT inhibitor-induced apoptosis in breast cancer cells.

Breast Cancer Res Treat 2014 Jul 13;146(1):99-108. Epub 2014 Jun 13.

UPMC Cancer Research Pavilion, University of Pittsburgh Cancer Institute, Suite 500, 5150 Centre Ave, Pittsburgh, PA, 15232, USA.

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http://dx.doi.org/10.1007/s10549-014-3012-9DOI Listing
July 2014

Invasive lobular carcinoma cell lines are characterized by unique estrogen-mediated gene expression patterns and altered tamoxifen response.

Cancer Res 2014 Mar 14;74(5):1463-74. Epub 2014 Jan 14.

Authors' Affiliations: Women's Cancer Research Center; Departments of Biomedical Informatics, Pharmacology and Chemical Biology, Biostatistics, Human Genetics, University of Pittsburgh; Department of Pathology, Magee-Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; and Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955299PMC
March 2014

The search for ESR1 mutations in breast cancer.

Nat Genet 2013 Dec;45(12):1415-6

Department of Pharmacology and Chemical Biology and Department of Medicine, University of Pittsburgh, Women's Cancer Research Center, University of Pittsburgh Cancer Institute and UPMC Cancer Center, and Magee-Womens Research Institute, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.2831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934882PMC
December 2013

Estrogen represses gene expression through reconfiguring chromatin structures.

Nucleic Acids Res 2013 Sep 1;41(17):8061-71. Epub 2013 Jul 1.

Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, USA, Department of Computer Science, University of Pittsburgh, Pittsburgh, PA, USA, Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA, Women's Cancer Research Center, University of Pittsburgh, Pittsburgh, PA, USA, Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA, USA and Fondazione Ri.MED, Palermo, Italy.

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http://dx.doi.org/10.1093/nar/gkt586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783169PMC
September 2013

Using mice to treat (wo)men: mining genetic changes in patient xenografts to attack breast cancer.

Cell Rep 2013 Sep;4(6):1061-2

Women's Cancer Research Center, University of Pittsburgh Cancer Institute and UPMC Cancer Center, Magee-Womens Hospital and Magee-Womens Research Institute, Departments of Pharmacology and Chemical Biology and Medicine, University of Pittsburgh, Pittsburgh 15213, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2013.09.008DOI Listing
September 2013

Invasive lobular carcinoma of the breast: patient response to systemic endocrine therapy and hormone response in model systems.

Steroids 2013 Jun 21;78(6):568-75. Epub 2012 Nov 21.

Department of Pharmacology and Chemical Biology, University of Pittsburgh, United States.

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http://dx.doi.org/10.1016/j.steroids.2012.11.002DOI Listing
June 2013

The Scaffold attachment factor b1 (Safb1) regulates myogenic differentiation by facilitating the transition of myogenic gene chromatin from a repressed to an activated state.

Nucleic Acids Res 2013 Jun 22;41(11):5704-16. Epub 2013 Apr 22.

Department of Cell and Developmental Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.

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http://dx.doi.org/10.1093/nar/gkt285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675494PMC
June 2013

Progestins: pro-senescence therapy for ovarian cancer?

Cell Cycle 2013 Jun 17;12(11):1662-3. Epub 2013 May 17.

Womens Cancer Research Center, University of Pittsburgh Cancer Institute and Magee-Womens Research Institute; University of Pittsburgh, Pittsburgh, PA USA.

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http://dx.doi.org/10.4161/cc.25072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713123PMC
June 2013

Genetic associations with toxicity-related discontinuation of aromatase inhibitor therapy for breast cancer.

Breast Cancer Res Treat 2013 Apr 2;138(3):807-16. Epub 2013 Apr 2.

Breast Oncology Program, University of Michigan Comprehensive Cancer Center, 1500 East Medical Center Drive, Med Inn Bldg C450, Ann Arbor, MI 48109-5843, USA.

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http://dx.doi.org/10.1007/s10549-013-2504-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646626PMC
April 2013

Hormone response in ovarian cancer: time to reconsider as a clinical target?

Endocr Relat Cancer 2012 Dec 9;19(6):R255-79. Epub 2012 Nov 9.

Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pennsylvania, USA.

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http://dx.doi.org/10.1530/ERC-12-0175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696394PMC
December 2012

Elevated nuclear expression of the SMRT corepressor in breast cancer is associated with earlier tumor recurrence.

Breast Cancer Res Treat 2012 Nov 27;136(1):253-65. Epub 2012 Sep 27.

Department of Molecular & Cellular Biology, BCM130, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s10549-012-2262-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511772PMC
November 2012

Whole genome amplification of DNA for genotyping pharmacogenetics candidate genes.

Front Pharmacol 2012 30;3:54. Epub 2012 Mar 30.

Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine Indianapolis, IN, USA.

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http://journal.frontiersin.org/article/10.3389/fphar.2012.00
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http://dx.doi.org/10.3389/fphar.2012.00054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315790PMC
October 2012

BRCA1 promoter methylation status does not predict response to tamoxifen in sporadic breast cancer patients.

Breast Cancer Res Treat 2012 Aug 16;135(1):135-43. Epub 2012 Jun 16.

Department of Molecular & Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s10549-012-2117-2DOI Listing
August 2012

Epigenetics in breast cancer: what's new?

Breast Cancer Res 2011 1;13(6):225. Epub 2011 Nov 1.

University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1186/bcr2925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326545PMC
June 2012

Improving ChIP-seq peak-calling for functional co-regulator binding by integrating multiple sources of biological information.

BMC Genomics 2012 17;13 Suppl 1:S1. Epub 2012 Jan 17.

Department of Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1186/1471-2164-13-S1-S1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439677PMC
June 2012

To bind or not to bind--FoxA1 determines estrogen receptor action in breast cancer progression.

Breast Cancer Res 2012 Jun 19;14(3):312. Epub 2012 Jun 19.

University of Pittsburgh Cancer Institute, Magee Women's Research Institute, 204 Craft Avenue, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1186/bcr3146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446328PMC
June 2012

Functional characterization of a genetic polymorphism in the promoter of the ESR2 gene.

Horm Cancer 2012 Apr;3(1-2):37-43

Department of Medicine, Division of Clinical Pharmacology, Indiana University School of Medicine, Indianapolis, 46202, USA.

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http://link.springer.com/10.1007/s12672-011-0086-2
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http://dx.doi.org/10.1007/s12672-011-0086-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402208PMC
April 2012

Co-repressor activity of scaffold attachment factor B1 requires sumoylation.

Biochem Biophys Res Commun 2011 May 19;408(4):516-22. Epub 2011 Apr 19.

Breast Center and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.bbrc.2011.04.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955274PMC
May 2011

The Werner syndrome helicase protein is required for cell proliferation, immortalization, and tumorigenesis in Scaffold attachment factor B1 deficient mice.

Aging (Albany NY) 2011 Mar;3(3):277-90

Centre de Recherche en Cancérologie de l'Université Laval, Hôpital Hôtel‐Dieu de Québec, Québec City, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091521PMC
http://dx.doi.org/10.18632/aging.100300DOI Listing
March 2011

Low SAFB levels are associated with worse outcome in breast cancer patients.

Breast Cancer Res Treat 2010 Jun 10;121(2):503-9. Epub 2009 Jan 10.

Department of Medicine, Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s10549-008-0297-6DOI Listing
June 2010

Cooperative activation of cyclin D1 and progesterone receptor gene expression by the SRC-3 coactivator and SMRT corepressor.

Mol Endocrinol 2010 Jun 14;24(6):1187-202. Epub 2010 Apr 14.

Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1210/me.2009-0480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875800PMC
June 2010

Epigenetic regulation in estrogen receptor positive breast cancer--role in treatment response.

J Mammary Gland Biol Neoplasia 2010 Mar 27;15(1):35-47. Epub 2010 Jan 27.

Translational Biology and Molecular Medicine Graduate Program, Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1007/s10911-010-9166-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874203PMC
March 2010

Parity-induced decrease in systemic growth hormone alters mammary gland signaling: a potential role in pregnancy protection from breast cancer.

Cancer Prev Res (Phila) 2010 Mar 9;3(3):312-21. Epub 2010 Feb 9.

Breast Center, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-09-0074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833223PMC
March 2010

SAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cells.

J Biol Chem 2010 Feb 9;285(6):3608-16. Epub 2009 Nov 9.

Department of Medicine and Molecular and Cellular Biology, Lester and Sue Smith Breast Center, Texas Children's Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1074/jbc.M109.066431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823501PMC
February 2010

SAFB1's multiple functions in biological control-lots still to be done!

J Cell Biochem 2010 Feb;109(2):312-9

Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas, USA.

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http://dx.doi.org/10.1002/jcb.22420DOI Listing
February 2010

San Antonio breast cancer symposium--32nd annual meeting.

IDrugs 2010 Feb;13(2):80-1

Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

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February 2010

Histone deacetylase 7 and FoxA1 in estrogen-mediated repression of RPRM.

Mol Cell Biol 2010 Jan 16;30(2):399-412. Epub 2009 Nov 16.

Department of Molecular and Cellular Biology, 3 Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1128/MCB.00907-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798473PMC
January 2010

Scaffold Attachment Factor B1 (SAFB1) heterozygosity does not influence Wnt-1 or DMBA-induced tumorigenesis.

Mol Cancer 2009 Mar 6;8:15. Epub 2009 Mar 6.

Lester and Sue Smith Breast Center, Departments of Medicine, Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1186/1476-4598-8-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669049PMC
March 2009

Novel egg white-based 3-D cell culture system.

Biotechniques 2008 Aug;45(2):165-8, 170-1

Department of Medicine, Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.

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https://www.future-science.com/doi/10.2144/000112883
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August 2008

Estrogen-mediated downregulation of CD24 in breast cancer cells.

Int J Cancer 2008 Jul;123(1):66-72

Division of Molecular Mechanisms of Origin and Treatment of Breast Cancer, Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.

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http://dx.doi.org/10.1002/ijc.23480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587263PMC
July 2008

The role of single nucleotide polymorphisms in breast cancer metastasis.

Breast Cancer Res 2008 18;10(1):301. Epub 2008 Jan 18.

Division of Hematology Oncology, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1186/bcr1842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374952PMC
June 2008