Publications by authors named "Stefano Costanzi"

100Publications

Rituximab Followed by Belimumab Controls Severe Lupus Nephritis and Bullous Pemphigoid in Systemic Lupus Erythematosus Refractory to Several Combination Therapies.

Authors:

Luca Petricca Maria Rita Gigante Annamaria Paglionico Stefano Costanzi Gisella Vischini Clara Di Mario Valentina Varriano Giacomo Tanti Barbara Tolusso Stefano Alivernini Giuseppe Grandaliano Gianfranco Ferraccioli Elisa Gremese

Front Med (Lausanne) 2020 28;7:553075. Epub 2020 Oct 28.

Division of Rheumatology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

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October 2020

Lists of Chemical Warfare Agents and Precursors from International Nonproliferation Frameworks: Structural Annotation and Chemical Fingerprint Analysis.

Authors:

Stefano Costanzi Charlotte K Slavick Brent O Hutcheson Gregory D Koblentz Richard T Cupitt

J Chem Inf Model 2020 Oct 22;60(10):4804-4816. Epub 2020 Sep 22.

Stimson Center, 1211 Connecticut Avenue, NW, Washington, District of Columbia 20036, United States.

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October 2020

Deterioration in Clinical Status Is Not Enough to Suspend Eculizumab: A Genetic Complement-Mediated Atypical Hemolytic Uremic Syndrome Case Report.

Authors:

Luca Calvaruso Alessandro Naticchia Pietro Manuel Ferraro Gisella Vischini Stefano Costanzi

Case Rep Nephrol 2019 9;2019:9264824. Epub 2019 Jul 9.

U.O.C. Nefrologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

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July 2019

Influence of the Structural Accuracy of Homology Models on Their Applicability to Docking-Based Virtual Screening: The β Adrenergic Receptor as a Case Study.

Authors:

Stefano Costanzi Austin Cohen Abigail Danfora Marjan Dolatmoradi

J Chem Inf Model 2019 07 1;59(7):3177-3190. Epub 2019 Jul 1.

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July 2019

[The pathway of vasopressin as a pharmacological target in nephrology: a narrative review].

Authors:

Michi Recupero Pierluigi Fulignati Alessandro Naticchia Silvia D'Alonzo Francesca D'Ascenzo Stefano Costanzi

G Ital Nefrol 2018 Dec;35(6)

U.O.C. Nefrologia, Università cattolica del sacro cuore. Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italia.

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December 2018

Chiral analogues of (+)-cyclazosin as potent α-adrenoceptor selective antagonist.

Authors:

Gianni Sagratini Michela Buccioni Gabriella Marucci Elena Poggesi Matthew Skorski Stefano Costanzi Dario Giardinà

Bioorg Med Chem 2018 07 17;26(12):3502-3513. Epub 2018 May 17.

Scuola in Scienze del Farmaco e dei Prodotti della Salute, Università di Camerino, Via S. Agostino 1, 62032 Camerino, Italy.

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July 2018

Contrast-enhanced ultrasonography in chronic glomerulonephritides: correlation with histological parameters of disease activity.

Authors:

Manuela Nestola Nicoletta De Matthaeis Pietro Manuel Ferraro Paola Fuso Stefano Costanzi Gian Franco Zannoni Fabrizio Pizzolante Sabina Vasquez Quadra Giovanni Gambaro Gian Ludovico Rapaccini

J Ultrasound 2018 Jun 24;21(2):81-87. Epub 2018 Apr 24.

Gastroenterology Unit, Policlinico A. Gemelli, Catholic University, Largo Agostino Gemelli, 8, 00168, Rome, Italy.

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June 2018

Nerve Agents: What They Are, How They Work, How to Counter Them.

Authors:

Stefano Costanzi John-Hanson Machado Moriah Mitchell

ACS Chem Neurosci 2018 05 25;9(5):873-885. Epub 2018 Apr 25.

Department of Chemistry , The George Washington University , 800 22nd Street NW , Washington, DC 20052 , United States.

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May 2018

Defective activation of the MAPK/ERK pathway, leading to PARP1 and DNMT1 dysregulation, is a common defect in IgA nephropathy and Henoch-Schönlein purpura.

Authors:

Annamaria Milillo Clelia Molinario Stefano Costanzi Gisella Vischini Francesca La Carpia Francesco La Greca Donato Rigante Giovanni Gambaro Fiorella Gurrieri Eugenio Sangiorgi

J Nephrol 2018 Oct 1;31(5):731-741. Epub 2018 Mar 1.

Istituto di Medicina Genomica, Università Cattolica del Sacro Cuore, 00168, Roma, Italy.

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October 2018

Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library.

Proc Natl Acad Sci U S A 2017 02 27;114(7):1708-1713. Epub 2017 Jan 27.

Department of Medicine, Duke University Medical Center, Durham, NC 27710;

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February 2017

Computational Drug Target Screening through Protein Interaction Profiles.

Authors:

Santiago Vilar Elías Quezada Eugenio Uriarte Stefano Costanzi Fernanda Borges Dolores Viña George Hripcsak

Sci Rep 2016 11 15;6:36969. Epub 2016 Nov 15.

Department of Biomedical Informatics, Columbia University Medical Center, New York, NY 10032, USA.

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November 2016

Homology modeling of a Class A GPCR in the inactive conformation: A quantitative analysis of the correlation between model/template sequence identity and model accuracy.

Authors:

Stefano Costanzi Matthew Skorski Alessandro Deplano Brett Habermehl Mary Mendoza Keyun Wang Michelle Biederman Jessica Dawson Jia Gao

J Mol Graph Model 2016 11 4;70:140-152. Epub 2016 Oct 4.

Department of Chemistry, American University, Washington, DC 20016, USA.

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November 2016

Topological Analyses of Protein-Ligand Binding: a Network Approach.

Authors:

Stefano Costanzi

Curr Protein Pept Sci 2016 ;17(1):37-40

Department of Chemistry, American University, 4400 Massachusetts Ave, NW, 20016 Washington, DC, USA.

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September 2016

A SPRY2 mutation leading to MAPK/ERK pathway inhibition is associated with an autosomal dominant form of IgA nephropathy.

Authors:

Annamaria Milillo Francesca La Carpia Stefano Costanzi Vanessa D'Urbano Maurizio Martini Paola Lanuti Gisella Vischini Luigi M Larocca Marco Marchisio Sebastiano Miscia Antonio Amoroso Fiorella Gurrieri Eugenio Sangiorgi

Eur J Hum Genet 2015 Dec 18;23(12):1673-8. Epub 2015 Mar 18.

Institute of Medical Genetics, Catholic University, Rome, Italy.

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December 2015

Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation.

Authors:

Giampaolo Trivellin Adrian F Daly Fabio R Faucz Bo Yuan Liliya Rostomyan Darwin O Larco Marie Helene Schernthaner-Reiter Eva Szarek Letícia F Leal Jean-Hubert Caberg Emilie Castermans Chiara Villa Aggeliki Dimopoulos Prashant Chittiboina Paraskevi Xekouki Nalini Shah Daniel Metzger Philippe A Lysy Emanuele Ferrante Natalia Strebkova Nadia Mazerkina Maria Chiara Zatelli Maya Lodish Anelia Horvath Rodrigo Bertollo de Alexandre Allison D Manning Isaac Levy Margaret F Keil Maria de la Luz Sierra Leonor Palmeira Wouter Coppieters Michel Georges Luciana A Naves Mauricette Jamar Vincent Bours T John Wu Catherine S Choong Jerome Bertherat Philippe Chanson Peter Kamenický William E Farrell Anne Barlier Martha Quezado Ivana Bjelobaba Stanko S Stojilkovic Jurgen Wess Stefano Costanzi Pengfei Liu James R Lupski Albert Beckers Constantine A Stratakis

N Engl J Med 2014 Dec 3;371(25):2363-74. Epub 2014 Dec 3.

The authors' affiliations are listed in the Appendix.

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December 2014

Computational studies to predict or explain G protein coupled receptor polypharmacology.

Authors:

Kenneth A Jacobson Stefano Costanzi Silvia Paoletta

Trends Pharmacol Sci 2014 Dec 14;35(12):658-63. Epub 2014 Nov 14.

Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0810, USA.

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December 2014

Modeling G protein-coupled receptors in complex with biased agonists.

Authors:

Stefano Costanzi

Trends Pharmacol Sci 2014 Jun 2;35(6):277-83. Epub 2014 May 2.

Department of Chemistry, American University, Washington, DC 20016, USA; Center for Behavioral Neuroscience, American University, Washington, DC 20016, USA. Electronic address:

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June 2014

Human cytidine deaminase: a biochemical characterization of its naturally occurring variants.

Authors:

Daniela Micozzi Francesco Martino Carpi Stefania Pucciarelli Valeria Polzonetti Paolo Polidori Santiago Vilar Brian Williams Stefano Costanzi Silvia Vincenzetti

Int J Biol Macromol 2014 Feb 29;63:64-74. Epub 2013 Oct 29.

School of Veterinary Medical Sciences, University of Camerino, via circonvallazione 93/95, 62024 Matelica, MC, Italy. Electronic address:

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February 2014

The GPCR crystallography boom: providing an invaluable source of structural information and expanding the scope of homology modeling.

Authors:

Stefano Costanzi Keyun Wang

Adv Exp Med Biol 2014 ;796:3-13

Department of Chemistry and Center for Behavioral Neuroscience, American University, Washington, DC, 20016, USA,

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May 2014

Novel structural and functional insights into M3 muscarinic receptor dimer/oligomer formation.

Authors:

Jianxin Hu Kelly Hu Tong Liu Matthew K Stern Rajendra Mistry R A John Challiss Stefano Costanzi Jürgen Wess

J Biol Chem 2013 Nov 16;288(48):34777-90. Epub 2013 Oct 16.

From the Molecular Signaling Section, Laboratory of Bioorganic Chemistry, NIDDK, National Institutes of Health, Bethesda, Maryland 20892.

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November 2013