Publications by authors named "Stefano Biagioni"

44Publications

Phosphodiesterase Inhibitors: Could They Be Beneficial for the Treatment of COVID-19?

Authors:
Mauro Giorgi Silvia Cardarelli Federica Ragusa Michele Saliola Stefano Biagioni Giancarlo Poiana Fabio Naro Mara Massimi

Int J Mol Sci 2020 Jul 27;21(15). Epub 2020 Jul 27.

Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.

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July 2020

X-ray irradiated cultures of mouse cortical neural stem/progenitor cells recover cell viability and proliferation with dose-dependent kinetics.

Authors:
Valerio Licursi Silvia Anzellotti Jessica Favaro Serena Sineri Nicoletta Carucci Enrico Cundari Mario Fiore Giulia Guarguaglini Simone Pippa Paola S Nisi Fiammetta Vernì Stefano Biagioni Emanuele Cacci Roberto Amendola Giuseppe Lupo Rodolfo Negri

Sci Rep 2020 04 16;10(1):6562. Epub 2020 Apr 16.

Department of Biology and Biotechnology "C. Darwin", Sapienza University of Rome, Rome, Italy.

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April 2020

Dystonia: Sparse Synapses for D2 Receptors in Striatum of a DYT1 Knock-out Mouse Model.

Authors:
Vincenza D'Angelo Emanuela Paldino Silvia Cardarelli Roberto Sorge Francesca Romana Fusco Stefano Biagioni Nicola Biagio Mercuri Mauro Giorgi Giuseppe Sancesario

Int J Mol Sci 2020 Feb 6;21(3). Epub 2020 Feb 6.

Department of Systems Medicine, Tor Vergata University of Rome, via Montpellier 1, 00133 Rome, Italy.

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February 2020

Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies.

Authors:
Michela Puxeddu Hongliang Shen Ruoli Bai Antonio Coluccia Marianna Nalli Carmela Mazzoccoli Eleonora Da Pozzo Chiara Cavallini Claudia Martini Viviana Orlando Stefano Biagioni Cristina Mazzoni Addolorata Maria Luce Coluccia Ernest Hamel Te Liu Romano Silvestri Giuseppe La Regina

Eur J Med Chem 2020 Jan 2;185:111828. Epub 2019 Nov 2.

Laboratory Affiliated with the Institute Pasteur Italy - Cenci Bolognetti Foundation, Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185, Roma, Italy. Electronic address:

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January 2020

Extracellular Vesicle-Induced Differentiation of Neural Stem Progenitor Cells.

Authors:
Eleonora Stronati Roberta Conti Emanuele Cacci Silvia Cardarelli Stefano Biagioni Giancarlo Poiana

Int J Mol Sci 2019 Jul 27;20(15). Epub 2019 Jul 27.

Dipartimento di Biologia e Biotecnologie "Charles Darwin", Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185 Roma, Italy.

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July 2019

Molecular Signatures of the Aging Brain: Finding the Links Between Genes and Phenotypes.

Authors:
Giuseppe Lupo Silvana Gaetani Emanuele Cacci Stefano Biagioni Rodolfo Negri

Neurotherapeutics 2019 07;16(3):543-553

Department of Biology and Biotechnology "C. Darwin", Sapienza University of Rome, Piazzale A. Moro, 00185, Rome, Italy.

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July 2019

Drug Design and Synthesis of First in Class PDZ1 Targeting NHERF1 Inhibitors as Anticancer Agents.

Authors:
Antonio Coluccia Giuseppe La Regina Valentina Naccarato Marianna Nalli Viviana Orlando Stefano Biagioni Maria Laura De Angelis Marta Baiocchi Candice Gautier Stefano Gianni Fiorella Di Pastena Laura Di Magno Gianluca Canettieri Addolorata Maria Luce Coluccia Romano Silvestri

ACS Med Chem Lett 2019 Apr 14;10(4):499-503. Epub 2019 Jan 14.

Department of Drug Chemistry and Technologies, Sapienza University of Rome, Laboratory affiliated to Istituto Pasteur Italia - Fondazione Cenci Bolognetti, Piazzale Aldo Moro 5, I-00185 Roma, Italy.

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April 2019

Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death.

Authors:
Maria Antonietta Ajmone-Cat Angela Onori Camilla Toselli Eleonora Stronati Mariangela Morlando Irene Bozzoni Emanuela Monni Zaal Kokaia Giuseppe Lupo Luisa Minghetti Stefano Biagioni Emanuele Cacci

Sci Rep 2019 03 14;9(1):4572. Epub 2019 Mar 14.

Department of Biology and Biotechnology "Charles Darwin", Sapienza University of Rome, Rome, Italy.

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March 2019

Molecular Mechanisms of Neurogenic Aging in the Adult Mouse Subventricular Zone.

Authors:
Giuseppe Lupo Roberta Gioia Paola Serena Nisi Stefano Biagioni Emanuele Cacci

J Exp Neurosci 2019 19;13:1179069519829040. Epub 2019 Feb 19.

Department of Biology and Biotechnology "Charles Darwin", Sapienza University of Rome, Rome, Italy.

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February 2019

Metabolic role of cGMP in S. cerevisiae: the murine phosphodiesterase-5 activity affects yeast cell proliferation by altering the cAMP/cGMP equilibrium.

Authors:
Silvia Cardarelli Mauro Giorgi Giancarlo Poiana Stefano Biagioni Michele Saliola

FEMS Yeast Res 2019 05;19(3)

Department of Biology and Biotechnology "C. Darwin", Sapienza University of Rome, Piazzale A. Moro, Rome 5, 00185, Italy.

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May 2019

The oligomeric assembly of the phosphodiesterase-5 is a mixture of dimers and tetramers: A putative role in the regulation of function.

Authors:
Silvia Cardarelli Adriana Erica Miele Carlotta Zamparelli Stefano Biagioni Fabio Naro Francesco Malatesta Mauro Giorgi Michele Saliola

Biochim Biophys Acta Gen Subj 2018 10 17;1862(10):2183-2190. Epub 2018 Jul 17.

Department of Biology and Biotechnology "C. Darwin", Sapienza University of Rome, Piazzale A. Moro 5, 00185 Rome, Italy. Electronic address:

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October 2018

Egr-1 Maintains NSC Proliferation and Its Overexpression Counteracts Cell Cycle Exit Triggered by the Withdrawal of Epidermal Growth Factor.

Authors:
Arcangela Anna Cera Emanuele Cacci Camilla Toselli Silvia Cardarelli Alessandra Bernardi Roberta Gioia Mauro Giorgi Giancarlo Poiana Stefano Biagioni

Dev Neurosci 2018 5;40(3):223-233. Epub 2018 Jul 5.

Dipartimento di Biologia e Biotecnologie "Charles Darwin", Unità di Ricerca in Neurobiologia e Centro di Ricerca in Neurobiologia "Daniel Bovet", Sapienza Università di Roma, Rome, Italy.

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January 2019

Molecular profiling of aged neural progenitors identifies Dbx2 as a candidate regulator of age-associated neurogenic decline.

Authors:
Giuseppe Lupo Paola S Nisi Pilar Esteve Yu-Lee Paul Clara Lopes Novo Ben Sidders Muhammad A Khan Stefano Biagioni Hai-Kun Liu Paola Bovolenta Emanuele Cacci Peter J Rugg-Gunn

Aging Cell 2018 06 5;17(3):e12745. Epub 2018 Mar 5.

Epigenetics Programme, The Babraham Institute, Cambridge, UK.

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June 2018

Use of the KlADH3 promoter for the quantitative production of the murine PDE5A isoforms in the yeast Kluyveromyces lactis.

Authors:
Silvia Cardarelli Mauro Giorgi Fabio Naro Francesco Malatesta Stefano Biagioni Michele Saliola

Microb Cell Fact 2017 Sep 22;16(1):159. Epub 2017 Sep 22.

Department of Biology and Biotechnology "C. Darwin", Sapienza University of Rome, Piazzale A. Moro 5, 00185, Rome, Italy.

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September 2017

Transcriptional response of genes to retinoid signalling is regionally restricted along the neural tube rostrocaudal axis.

Authors:
Nicoletta Carucci Emanuele Cacci Paola S Nisi Valerio Licursi Yu-Lee Paul Stefano Biagioni Rodolfo Negri Peter J Rugg-Gunn Giuseppe Lupo

R Soc Open Sci 2017 Apr 5;4(4):160913. Epub 2017 Apr 5.

Istituto Pasteur- Fondazione Cenci Bolognetti, Sapienza University of Rome, 00185 Rome, Italy.

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April 2017

Phosphodiesterase-10A Inverse Changes in Striatopallidal and Striatoentopeduncular Pathways of a Transgenic Mouse Model of Dystonia.

Authors:
Vincenza D'Angelo Valentina Castelli Mauro Giorgi Silvia Cardarelli Ilaria Saverioni Francesca Palumbo Paola Bonsi Antonio Pisani Carmela Giampà Roberto Sorge Stefano Biagioni Francesca R Fusco Giuseppe Sancesario

J Neurosci 2017 02 23;37(8):2112-2124. Epub 2017 Jan 23.

Department of Systems Medicine, Tor Vergata University of Rome, 00133 Rome, Italy,

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February 2017

Dysregulated Homeostasis of Acetylcholine Levels in Immune Cells of RR-Multiple Sclerosis Patients.

Authors:
Maria Di Bari Marcella Reale Marta Di Nicola Viviana Orlando Sabrina Galizia Italo Porfilio Erica Costantini Chiara D'Angelo Serena Ruggieri Stefano Biagioni Claudio Gasperini Ada Maria Tata

Int J Mol Sci 2016 Nov 30;17(12). Epub 2016 Nov 30.

Department of Biology and Biotechnologies Charles Darwin, Research, Center of Neurobiology Daniel Bovet, Sapienza University of Rome, 00185 Rome, Italy.

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November 2016

Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival.

Authors:
Mara Massimi Silvia Cardarelli Francesca Galli Maria Federica Giardi Federica Ragusa Nadia Panera Benedetta Cinque Maria Grazia Cifone Stefano Biagioni Mauro Giorgi

J Cell Biochem 2017 06 30;118(6):1401-1411. Epub 2016 Nov 30.

Department of Biology and Biotechnology "Charles Darwin", Sapienza University of Rome, Rome, Italy.

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June 2017

Lamin A/C Is Required for ChAT-Dependent Neuroblastoma Differentiation.

Authors:
Loredana Guglielmi Marta Nardella Carla Musa Ilaria Iannetti Ivan Arisi Mara D'Onofrio Andrea Storti Alessandra Valentini Emanuele Cacci Stefano Biagioni Gabriella Augusti-Tocco Igea D'Agnano Armando Felsani

Mol Neurobiol 2017 07 25;54(5):3729-3744. Epub 2016 May 25.

CNR, Institute of Cell Biology and Neurobiology (IBCN), Rome, Italy.

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July 2017

Histone Methylation and microRNA-dependent Regulation of Epigenetic Activities in Neural Progenitor Self-Renewal and Differentiation.

Authors:
Emanuele Cacci Rodolfo Negri Stefano Biagioni Giuseppe Lupo

Curr Top Med Chem 2017 ;17(7):794-807

Department of Biology and Biotechnology "Charles Darwin", Sapienza University of Rome, Rome, Italy.

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February 2017