Stefanie Heynck

Stefanie Heynck

UNVERIFIED PROFILE

Are you Stefanie Heynck?   Register this Author

Register author
Stefanie Heynck

Stefanie Heynck

Publications by authors named "Stefanie Heynck"

Are you Stefanie Heynck?   Register this Author

14Publications

619Reads

22Profile Views

Targeting gain of function and resistance mutations in Abl and KIT by hybrid compound design.

J Med Chem 2013 Jul 10;56(14):5757-72. Epub 2013 Jul 10.

Department of Chemistry and Chemical Biology, Technical University of Dortmund, Otto-Hahn-Strasse 6, D-44227 Dortmund, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jm4004076DOI Listing
July 2013

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer.

Nat Genet 2012 Oct 2;44(10):1104-10. Epub 2012 Sep 2.

Department of Translational Genomics, University of Cologne, Cologne, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.2396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915822PMC
October 2012

ALK mutations conferring differential resistance to structurally diverse ALK inhibitors.

Clin Cancer Res 2011 Dec 26;17(23):7394-401. Epub 2011 Sep 26.

Max Planck Institute for Neurological Research, Klaus-Joachim-Zülch Laboratories of the Max Planck Society, Köln, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-11-1648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382103PMC
December 2011

Synthesis and biological evaluation of 7-substituted-1-(3-bromophenylamino)isoquinoline-4-carbonitriles as inhibitors of myosin light chain kinase and epidermal growth factor receptor.

Bioorg Med Chem 2011 Jan 10;19(1):429-39. Epub 2010 Nov 10.

Chemical Genomics Centre of the Max Planck Society, Otto-Hahn-Strasse 15, 44227 Dortmund, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmc.2010.11.007DOI Listing
January 2011

Analysis of compound synergy in high-throughput cellular screens by population-based lifetime modeling.

PLoS One 2010 Jan 27;5(1):e8919. Epub 2010 Jan 27.

Max Planck Institute for Neurological Research with Klaus-Joachim-Zülch Laboratories of the Max Planck Society and the Medical Faculty of the University of Köln, Max Planck Society, Köln, Germany.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008919PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811738PMC
January 2010