Publications Authored by Stefan Schulte-Merker

The von Hippel-Lindau Gene Is Required to Maintain Renal Proximal Tubule and Glomerulus Integrity in Zebrafish Larvae.

Authors:

Ellen van Rooijen Glenn van de Hoek Ive Logister Henry Ajzenberg Nine V A M Knoers Freek van Eeden Emile E Voest Stefan Schulte-Merker Rachel H Giles

Nephron 2018 17;138(4):310-323. Epub 2018 Jan 17.

Department of Medical Oncology, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1159/000484096	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492518	PMC

September 2019

Zebrafish: Housing and husbandry recommendations.

Authors:

Peter Aleström Livia D'Angelo Paul J Midtlyng Daniel F Schorderet Stefan Schulte-Merker Frederic Sohm Susan Warner

Lab Anim 2019 Sep 11:23677219869037. Epub 2019 Sep 11.

Karolinska Institutet, Comparative Medicine, Stockholm, Sweden.

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http://dx.doi.org/10.1177/0023677219869037	DOI Listing

September 2019

Cerebrovascular endothelial cells form transient Notch-dependent cystic structures in zebrafish.

Authors:

Elisabeth C Kugler Max van Lessen Stephan Daetwyler Karishma Chhabria Aaron M Savage Vishmi Silva Karen Plant Ryan B MacDonald Jan Huisken Robert N Wilkinson Stefan Schulte-Merker Paul Armitage Timothy Ja Chico

EMBO Rep 2019 Aug 18;20(8):e47047. Epub 2019 Jun 18.

Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, UK.

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http://dx.doi.org/10.15252/embr.201847047	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680135	PMC

August 2019

Zebrafish facial lymphatics develop through sequential addition of venous and non-venous progenitors.

Authors:

Tiffany Cy Eng Wenxuan Chen Kazuhide S Okuda June P Misa Yvonne Padberg Kathryn E Crosier Philip S Crosier Christopher J Hall Stefan Schulte-Merker Benjamin M Hogan Jonathan W Astin

EMBO Rep 2019 May 15;20(5). Epub 2019 Mar 15.

Department of Molecular Medicine & Pathology, School of Medical Sciences, The University of Auckland, Auckland, New Zealand

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http://dx.doi.org/10.15252/embr.201847079	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501020	PMC

May 2019

Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependent pigment progenitors in zebrafish.

Authors:

Karen Camargo-Sosa Sarah Colanesi Jeanette Müller Stefan Schulte-Merker Derek Stemple E Elizabeth Patton Robert N Kelsh

PLoS Genet 2019 02 27;15(2):e1007941. Epub 2019 Feb 27.

Department of Biology and Biochemistry and Centre for Regenerative Medicine, University of Bath, Claverton Down, Bath, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1007941	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392274	PMC

February 2019

Notochord Injury Assays that Stimulate Transcriptional Responses in Zebrafish Larvae.

Authors:

Zhiqiang Zeng Juan C Lopez-Baez Laura Lleras-Forero Hannah Brunsdon Cameron Wyatt Witold Rybski Nicholas D Hastie Stefan Schulte-Merker E Elizabeth Patton

Bio Protoc 2018 Dec;8(23):e3100

MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh, EH4 2XU, The United Kingdom.

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http://dx.doi.org/10.21769/BioProtoc.3100	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309551	PMC

December 2018

Consensus guidelines for the use and interpretation of angiogenesis assays.

Authors:

Patrycja Nowak-Sliwinska Kari Alitalo Elizabeth Allen Andrey Anisimov Alfred C Aplin Robert Auerbach Hellmut G Augustin David O Bates Judy R van Beijnum R Hugh F Bender Gabriele Bergers Andreas Bikfalvi Joyce Bischoff Barbara C Böck Peter C Brooks Federico Bussolino Bertan Cakir Peter Carmeliet Daniel Castranova Anca M Cimpean Ondine Cleaver George Coukos George E Davis Michele De Palma Anna Dimberg Ruud P M Dings Valentin Djonov Andrew C Dudley Neil P Dufton Sarah-Maria Fendt Napoleone Ferrara Marcus Fruttiger Dai Fukumura Bart Ghesquière Yan Gong Robert J Griffin Adrian L Harris Christopher C W Hughes Nan W Hultgren M Luisa Iruela-Arispe Melita Irving Rakesh K Jain Raghu Kalluri Joanna Kalucka Robert S Kerbel Jan Kitajewski Ingeborg Klaassen Hynda K Kleinmann Pieter Koolwijk Elisabeth Kuczynski Brenda R Kwak Koen Marien Juan M Melero-Martin Lance L Munn Roberto F Nicosia Agnes Noel Jussi Nurro Anna-Karin Olsson Tatiana V Petrova Kristian Pietras Roberto Pili Jeffrey W Pollard Mark J Post Paul H A Quax Gabriel A Rabinovich Marius Raica Anna M Randi Domenico Ribatti Curzio Ruegg Reinier O Schlingemann Stefan Schulte-Merker Lois E H Smith Jonathan W Song Steven A Stacker Jimmy Stalin Amber N Stratman Maureen Van de Velde Victor W M van Hinsbergh Peter B Vermeulen Johannes Waltenberger Brant M Weinstein Hong Xin Bahar Yetkin-Arik Seppo Yla-Herttuala Mervin C Yoder Arjan W Griffioen

Angiogenesis 2018 08;21(3):425-532

Angiogenesis Laboratory, Department of Medical Oncology, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10456-018-9613-x	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237663	PMC

August 2018

From fish embryos to human patients: lymphangiogenesis in development and disease.

Authors:

Cristina Mauri Guangxia Wang Stefan Schulte-Merker

Curr Opin Immunol 2018 08 23;53:167-172. Epub 2018 May 23.

Institute for Cardiovascular Organogenesis and Regeneration, Faculty of Medicine, University of Münster, Münster, Germany; Cells-in-Motion Cluster of Excellence, University of Münster, Münster, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2018.05.003	DOI Listing

August 2018

A Novel Splice-Site Mutation in Is Associated with Congenital Primary Lymphoedema of Gordon.

Authors:

Noeline Nadarajah Dörte Schulte Vivienne McConnell Silvia Martin-Almedina Christina Karapouliou Peter S Mortimer Steve Jeffery Stefan Schulte-Merker Kristiana Gordon Sahar Mansour Pia Ostergaard

Int J Mol Sci 2018 Aug 1;19(8). Epub 2018 Aug 1.

Molecular and Clinical Sciences Institute, St George's University of London, London SW17 0RE, UK.

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http://dx.doi.org/10.3390/ijms19082259	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121331	PMC

August 2018

Direct activation of chordoblasts by retinoic acid is required for segmented centra mineralization during zebrafish spine development.

Authors:

Hans-Martin Pogoda Iris Riedl-Quinkertz Heiko Löhr Joshua S Waxman Rodney M Dale Jacek Topczewski Stefan Schulte-Merker Matthias Hammerschmidt

Development 2018 05 8;145(9). Epub 2018 May 8.

Department of Biology, Institute of Zoology - Developmental Biology, University of Cologne, 50674 Cologne, Germany

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http://dx.doi.org/10.1242/dev.159418	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992598	PMC

May 2018

A blood capillary plexus-derived population of progenitor cells contributes to genesis of the dermal lymphatic vasculature during embryonic development.

Authors:

Cathy Pichol-Thievend Kelly L Betterman Xiaolei Liu Wanshu Ma Renae Skoczylas Emmanuelle Lesieur Frank L Bos Dorte Schulte Stefan Schulte-Merker Benjamin M Hogan Guillermo Oliver Natasha L Harvey Mathias Francois

Development 2018 05 17;145(10). Epub 2018 May 17.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia

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http://dx.doi.org/10.1242/dev.160184	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001371	PMC

May 2018

Segmentation of the zebrafish axial skeleton relies on notochord sheath cells and not on the segmentation clock.

Authors:

Laura Lleras Forero Rachna Narayanan Leonie Fa Huitema Maaike VanBergen Alexander Apschner Josi Peterson-Maduro Ive Logister Guillaume Valentin Luis G Morelli Andrew C Oates Stefan Schulte-Merker

Elife 2018 04 6;7. Epub 2018 Apr 6.

Institute for Cardiovascular Organogenesis and Regeneration, Faculty of Medicine, WWU Münster, Münster, Germany.

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http://dx.doi.org/10.7554/eLife.33843	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962341	PMC

April 2018

defines a wound-specific sheath cell subpopulation associated with notochord repair.

Authors:

Juan Carlos Lopez-Baez Daniel J Simpson Laura LLeras Forero Zhiqiang Zeng Hannah Brunsdon Angela Salzano Alessandro Brombin Cameron Wyatt Witold Rybski Leonie F A Huitema Rodney M Dale Koichi Kawakami Christoph Englert Tamir Chandra Stefan Schulte-Merker Nicholas D Hastie E Elizabeth Patton

Elife 2018 02 6;7. Epub 2018 Feb 6.

MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.7554/eLife.30657	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811212	PMC

February 2018

Spine Patterning Is Guided by Segmentation of the Notochord Sheath.

Authors:

Susan Wopat Jennifer Bagwell Kaelyn D Sumigray Amy L Dickson Leonie F A Huitema Kenneth D Poss Stefan Schulte-Merker Michel Bagnat

Cell Rep 2018 02;22(8):2026-2038

Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA; Regeneration Next, Duke University, Durham, NC 27710, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.01.084	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860813	PMC

February 2018

Report of Workshop on Euthanasia for Zebrafish-A Matter of Welfare and Science.

Authors:

Almut Köhler Chereen Collymore Karin Finger-Baier Robert Geisler Larissa Kaufmann Kieran C Pounder Stefan Schulte-Merker Ana Valentim Zoltan M Varga Jürgen Weiss Uwe Strähle

Zebrafish 2017 12 2;14(6):547-551. Epub 2017 Oct 2.

5 European Society for Fish Models in Biology and Medicine, Institute of Toxicology and Genetics, Karlsruhe Institute of Technology (KIT) , Karlsruhe, Germany .

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http://dx.doi.org/10.1089/zeb.2017.1508	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706616	PMC

December 2017

Correction: SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development. Development doi: 10.1242/dev.146241.

Development 2017 10;144(20):3847-3848

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia

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http://dx.doi.org/10.1242/dev.159715	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675453	PMC

October 2017

Guidelines for morpholino use in zebrafish.

Authors:

Didier Y R Stainier Erez Raz Nathan D Lawson Stephen C Ekker Rebecca D Burdine Judith S Eisen Philip W Ingham Stefan Schulte-Merker Deborah Yelon Brant M Weinstein Mary C Mullins Stephen W Wilson Lalita Ramakrishnan Sharon L Amacher Stephan C F Neuhauss Anming Meng Naoki Mochizuki Pertti Panula Cecilia B Moens

PLoS Genet 2017 10 19;13(10):e1007000. Epub 2017 Oct 19.

Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007000	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648102	PMC

October 2017

How to Plumb a Pisces: Understanding Vascular Development and Disease Using Zebrafish Embryos.

Authors:

Benjamin M Hogan Stefan Schulte-Merker

Dev Cell 2017 09;42(6):567-583

Institute for Cardiovascular Organogenesis and Regeneration, Faculty of Medicine, WWU Münster, Münster 48149, Germany; Cells-in-Motion Cluster of Excellence (EXC-1003), WWU Münster, 48149 Münster, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2017.08.015	DOI Listing

September 2017

SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development.

Development 2017 07 15;144(14):2629-2639. Epub 2017 Jun 15.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia

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http://dx.doi.org/10.1242/dev.146241	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536923	PMC

July 2017

Intracellular uptake of macromolecules by brain lymphatic endothelial cells during zebrafish embryonic development.

Authors:

Max van Lessen Shannon Shibata-Germanos Andreas van Impel Thomas A Hawkins Jason Rihel Stefan Schulte-Merker

Elife 2017 05 12;6. Epub 2017 May 12.

Institute of Cardiovascular Organogenesis and Regeneration, WWU Münster, Münster, Germany.

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http://dx.doi.org/10.7554/eLife.25932	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457137	PMC

May 2017

An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation.

Authors:

Terhi Karpanen Yvonne Padberg Serge A van de Pavert Cathrin Dierkes Nanami Morooka Josi Peterson-Maduro Glenn van de Hoek Max Adrian Naoki Mochizuki Kiyotoshi Sekiguchi Friedemann Kiefer Dörte Schulte Stefan Schulte-Merker

Circ Res 2017 Apr 8;120(8):1263-1275. Epub 2017 Feb 8.

From the Hubrecht Institute, KNAW and UMC Utrecht, Utrecht, the Netherlands (T.K., S.A.v.d.P., J.P.-M., G.v.d.H., M.A., S.S.-M.); Institute of Cardiovascular Organogenesis and Regeneration, Faculty of Medicine, WWU Münster, Germany (Y.P., D.S., S.S.-M.); CiM Cluster of Excellence (EXC 1003-CiM), Münster, Germany (Y.P., D.S., S.S.-M.); Max Planck Institute for Molecular Biomedicine, Münster, Germany (C.D., F.K.); Laboratory of Extracellular Matrix Biochemistry, Institute for Protein Research, Osaka University, Suita, Japan (N.M., K.S.); and Department of Cell Biology, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka, Japan (N.M.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.308813	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389596	PMC

April 2017

Neuronal sFlt1 and Vegfaa determine venous sprouting and spinal cord vascularization.

Authors:

Raphael Wild Alina Klems Masanari Takamiya Yuya Hayashi Uwe Strähle Koji Ando Naoki Mochizuki Andreas van Impel Stefan Schulte-Merker Janna Krueger Laetitia Preau Ferdinand le Noble

Nat Commun 2017 01 10;8:13991. Epub 2017 Jan 10.

Department of Cell and Developmental Biology, Institute of Zoology (ZOO) Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 4, 76131 Karlsruhe, Germany.

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http://dx.doi.org/10.1038/ncomms13991	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234075	PMC

January 2017

FAM222B Is Not a Likely Novel Candidate Gene for Cerebral Cavernous Malformations.

Authors:

Stefanie Spiegler Bettina Kirchmaier Matthias Rath G Christoph Korenke Fabian Tetzlaff Maartje van de Vorst Kornelia Neveling Amparo Acker-Palmer Andreas W Kuss Christian Gilissen Andreas Fischer Stefan Schulte-Merker Ute Felbor

Mol Syndromol 2016 Jul 18;7(3):144-52. Epub 2016 Jun 18.

Department of Human Genetics, University Medicine Greifswald and Interfaculty Institute of Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1159/000446884	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988258	PMC

July 2016

Genome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo.

Authors:

Alain de Bruin Peter W A Cornelissen Bettina C Kirchmaier Michal Mokry Elhadi Iich Ella Nirmala Kuo-Hsuan Liang Anna M D Végh Koen T Scholman Marian J Groot Koerkamp Frank C Holstege Edwin Cuppen Stefan Schulte-Merker Walbert J Bakker

Nucleic Acids Res 2016 05 17;44(8):3549-66. Epub 2015 Dec 17.

Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/nar/gkv1471	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856960	PMC

May 2016

Identification of novel osteogenic compounds by an ex-vivo sp7:luciferase zebrafish scale assay.

Authors:

Erik de Vrieze Jan Zethof Stefan Schulte-Merker Gert Flik Juriaan R Metz

Bone 2015 May 16;74:106-13. Epub 2015 Jan 16.

Department of Organismal Animal Physiology, Institute for Water and Wetland Research, Faculty of Science, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.bone.2015.01.006	DOI Listing

May 2015

Functional Dissection of the CCBE1 Protein: A Crucial Requirement for the Collagen Repeat Domain.

Authors:

M Guy Roukens Josi Peterson-Maduro Yvonne Padberg Michael Jeltsch Veli-Matti Leppänen Frank L Bos Kari Alitalo Stefan Schulte-Merker Dörte Schulte

Circ Res 2015 May 26;116(10):1660-9. Epub 2015 Mar 26.

From the Hubrecht Institute, KNAW-UMC Utrecht, Utrecht, The Netherlands (M.G.R., J.P.M., Y.P., F.L.B., S.S.-M., D.S.); Cardiovascular Research Institute, University of California San Francisco (F.L.B.); Translational Cancer Biology Program, University of Helsinki, Biomedicum Helsinki, Helsinki, Finland (M.J., V.-M. L., K.A.); Wihuri Research Institute, Biomedicum Helsinki, Helsinki, Finland (M.J., V.-M. L., K.A.); Institute for Cardiovascular Organogenesis and Regeneration, Faculty of Medicine, WWU, Münster, Germany (Y.P., S.S.M., D.S.); and Cells-in-Motion Cluster of Excellence (EXC 1003-CiM), University of Münster, Münster, Germany (Y.P., S.S.M., D.S.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.304949	DOI Listing

May 2015

Sox7 controls arterial specification in conjunction with hey2 and efnb2 function.

Authors:

Dorien M A Hermkens Andreas van Impel Akihiro Urasaki Jeroen Bussmann Henricus J Duckers Stefan Schulte-Merker

Development 2015 May 1;142(9):1695-704. Epub 2015 Apr 1.

Hubrecht Institute - Royal Netherlands Academy of Arts and Sciences and University Medical Centre Utrecht, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands Cells-in-Motion Cluster of Excellence (EXC 1003 - CiM), University of Münster, 48149 Münster, Germany Institute for Cardiovascular Organogenesis and Regeneration, Faculty of Medicine, Westfälische Wilhelms-Universität Münster (WWU), Mendelstrasse 7, 48149 Münster, Germany

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http://dx.doi.org/10.1242/dev.117275	DOI Listing

May 2015

Vitamin K reduces hypermineralisation in zebrafish models of PXE and GACI.

Authors:

Eirinn W Mackay Alexander Apschner Stefan Schulte-Merker

Development 2015 Mar;142(6):1095-101

Hubrecht Institute - KNAW & University Medical Center Utrecht, Utrecht 3584 CT, The Netherlands EZO, WUR, Wageningen 6709 PG, The Netherlands Institute of Cardiovascular Organogenesis and Regeneration, University of Münster, Münster 48149, Germany Cells-in-Motion Cluster of Excellence (EXC 1003 - CiM), University of Münster, Münster 48149, Germany

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http://dx.doi.org/10.1242/dev.113811	DOI Listing

March 2015

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (cad) regulates Notch signaling and vascular development in zebrafish.

Authors:

Baptiste Coxam Christine Neyt Daniela R Grassini Ludovic Le Guen Kelly A Smith Stefan Schulte-Merker Benjamin M Hogan

Dev Dyn 2015 Jan 17;244(1):1-9. Epub 2014 Nov 17.

Division of Molecular Genetics and Development, Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.

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http://dx.doi.org/10.1002/dvdy.24209	DOI Listing

January 2015

Proteomics analysis of the zebrafish skeletal extracellular matrix.

Authors:

Maurijn Y Kessels Leonie F A Huitema Sjef Boeren Sander Kranenbarg Stefan Schulte-Merker Johan L van Leeuwen Sacco C de Vries

PLoS One 2014 7;9(3):e90568. Epub 2014 Mar 7.

Laboratory of Biochemistry, Wageningen University, Wageningen, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090568	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946537	PMC

December 2014

Out with the old, in with the new: reassessing morpholino knockdowns in light of genome editing technology.

Authors:

Stefan Schulte-Merker Didier Y R Stainier

Development 2014 Aug;141(16):3103-4

Max Planck Institute for Heart and Lung Research, Department of Developmental Genetics, Bad Nauheim 61231, Germany.

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http://dx.doi.org/10.1242/dev.112003	DOI Listing

August 2014

Zebrafish enpp1 mutants exhibit pathological mineralization, mimicking features of generalized arterial calcification of infancy (GACI) and pseudoxanthoma elasticum (PXE).

Authors:

Alexander Apschner Leonie F A Huitema Bas Ponsioen Josi Peterson-Maduro Stefan Schulte-Merker

Dis Model Mech 2014 Jul 6;7(7):811-22. Epub 2014 Jun 6.

Hubrecht Institute - KNAW & UMC Utrecht, 3548CT Utrecht, The Netherlands. WUR, Experimental Zoology, 3700AH Wageningen, The Netherlands. Institute of Cardiovascular Organogenesis and Regeneration, Faculty of Medicine, University of Münster, 48149 Münster, Germany.

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http://dx.doi.org/10.1242/dmm.015693	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073271	PMC

July 2014

Mature osteoblasts dedifferentiate in response to traumatic bone injury in the zebrafish fin and skull.

Authors:

Karina Geurtzen Franziska Knopf Daniel Wehner Leonie F A Huitema Stefan Schulte-Merker Gilbert Weidinger

Development 2014 Jun 12;141(11):2225-34. Epub 2014 May 12.

Institute for Biochemistry and Molecular Biology, Ulm University, 89081 Ulm, Germany

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http://dx.doi.org/10.1242/dev.105817	DOI Listing

June 2014

Pkd1 regulates lymphatic vascular morphogenesis during development.

Authors:

Baptiste Coxam Amélie Sabine Neil I Bower Kelly A Smith Cathy Pichol-Thievend Renae Skoczylas Jonathan W Astin Emmanuelle Frampton Muriel Jaquet Philip S Crosier Robert G Parton Natasha L Harvey Tatiana V Petrova Stefan Schulte-Merker Mathias Francois Benjamin M Hogan

Cell Rep 2014 May 24;7(3):623-33. Epub 2014 Apr 24.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.03.063	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005109	PMC

May 2014

Atypical E2fs control lymphangiogenesis through transcriptional regulation of Ccbe1 and Flt4.

Authors:

Bart G M W Weijts Andreas van Impel Stefan Schulte-Merker Alain de Bruin

PLoS One 2013 12;8(9):e73693. Epub 2013 Sep 12.

Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0073693	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771987	PMC

April 2014

Introductory remarks.

Authors:

Friedemann Kiefer Stefan Schulte-Merker

Adv Anat Embryol Cell Biol 2014 ;214:1-4

Mammalian Cell Signaling Laboratory, MPI for Molecular Biomedicine, Röntgenstrasse 20, 48149, Münster, Germany,

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http://dx.doi.org/10.1007/978-3-7091-1646-3_1	DOI Listing

April 2014

A fisheye view on lymphangiogenesis.

Authors:

Andreas van Impel Stefan Schulte-Merker

Adv Anat Embryol Cell Biol 2014 ;214:153-65

Hubrecht Institute, KNAW and UMC Utrecht, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.

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http://link.springer.com/content/pdf/10.1007/978-3-7091-1646	Web Search
http://link.springer.com/10.1007/978-3-7091-1646-3_12	Publisher Site
http://dx.doi.org/10.1007/978-3-7091-1646-3_12	DOI Listing

April 2014

Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity.

Nature 2014 Apr 19;508(7494):123-7. Epub 2014 Mar 19.

1] Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Av. Prof. Egas Moniz, Edifício Egas Moniz, 1649-028 Lisboa, Portugal [2].

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http://www.nature.com/articles/nature13158	Publisher Site
http://dx.doi.org/10.1038/nature13158	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932833	PMC

April 2014

Divergence of zebrafish and mouse lymphatic cell fate specification pathways.

Authors:

Andreas van Impel Zhonghua Zhao Dorien M A Hermkens M Guy Roukens Johanna C Fischer Josi Peterson-Maduro Henricus Duckers Elke A Ober Philip W Ingham Stefan Schulte-Merker

Development 2014 Mar 12;141(6):1228-38. Epub 2014 Feb 12.

Hubrecht Institute - KNAW & UMC Utrecht, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1242/dev.105031	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943180	PMC

March 2014

Ccbe1 regulates Vegfc-mediated induction of Vegfr3 signaling during embryonic lymphangiogenesis.

Authors:

Ludovic Le Guen Terhi Karpanen Dörte Schulte Nicole C Harris Katarzyna Koltowska Guy Roukens Neil I Bower Andreas van Impel Steven A Stacker Marc G Achen Stefan Schulte-Merker Benjamin M Hogan

Development 2014 Mar 12;141(6):1239-49. Epub 2014 Feb 12.

Division of Molecular Genetics and Development, Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4073, Australia.

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http://dx.doi.org/10.1242/dev.100495	DOI Listing

March 2014

A bone to pick with zebrafish.

Authors:

Eirinn W Mackay Alexander Apschner Stefan Schulte-Merker

Bonekey Rep 2013 Nov 13;2:445. Epub 2013 Nov 13.

Hubrecht Institute-KNAW & University Medical Centre Utrecht , Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/bonekey.2013.179	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844975	PMC

November 2013

The zebrafish common cardinal veins develop by a novel mechanism: lumen ensheathment.

Authors:

Christian S M Helker Annika Schuermann Terhi Karpanen Dagmar Zeuschner Heinz-Georg Belting Markus Affolter Stefan Schulte-Merker Wiebke Herzog

Development 2013 Jul 22;140(13):2776-86. Epub 2013 May 22.

University of Muenster, 48149 Muenster, Germany.

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http://dx.doi.org/10.1242/dev.091876	DOI Listing

July 2013

A versatile toolkit to produce sensitive FRET biosensors to visualize signaling in time and space.

Authors:

Rafael D Fritz Michel Letzelter Andreas Reimann Katrin Martin Ludovico Fusco Laila Ritsma Bas Ponsioen Erika Fluri Stefan Schulte-Merker Jacco van Rheenen Olivier Pertz

Sci Signal 2013 Jul 23;6(285):rs12. Epub 2013 Jul 23.

Institute of Biochemistry and Genetics, Department of Biomedicine, University of Basel, Mattenstrasse 28, 4058 Basel, Switzerland.

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http://dx.doi.org/10.1126/scisignal.2004135	DOI Listing

July 2013

Mutations in LRRC50 predispose zebrafish and humans to seminomas.

Authors:

Sander G Basten Erica E Davis Ad J M Gillis Ellen van Rooijen Hans Stoop Nikolina Babala Ive Logister Zachary G Heath Trudy N Jonges Nicholas Katsanis Emile E Voest Freek J van Eeden Rene H Medema René F Ketting Stefan Schulte-Merker Leendert H J Looijenga Rachel H Giles

PLoS Genet 2013 Apr 11;9(4):e1003384. Epub 2013 Apr 11.

Department of Medical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1371/journal.pgen.1003384	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627517	PMC

April 2013

A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy.

Authors:

René Hägerling Cathrin Pollmann Martin Andreas Christian Schmidt Harri Nurmi Ralf H Adams Kari Alitalo Volker Andresen Stefan Schulte-Merker Friedemann Kiefer

EMBO J 2013 Mar 8;32(5):629-44. Epub 2013 Jan 8.

Mammalian Cell Signaling Laboratory, Department of Vascular Cell Biology, Max Planck Institute for Molecular Biomedicine, Münster, Germany.

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https://pdfs.semanticscholar.org/9c3a/4052bf6cb49f9cf0a69f0c	Web Search
http://emboj.embopress.org/cgi/doi/10.1038/emboj.2012.340	Publisher Site
http://dx.doi.org/10.1038/emboj.2012.340	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3590982	PMC

March 2013

Mutation in vascular endothelial growth factor-C, a ligand for vascular endothelial growth factor receptor-3, is associated with autosomal dominant milroy-like primary lymphedema.

Authors:

Kristiana Gordon Dörte Schulte Glen Brice Michael A Simpson M Guy Roukens Andreas van Impel Fiona Connell Kamini Kalidas Steve Jeffery Peter S Mortimer Sahar Mansour Stefan Schulte-Merker Pia Ostergaard

Circ Res 2013 Mar 14;112(6):956-60. Epub 2013 Feb 14.

Human Genetics Research Centre, Biomedical Sciences, St George's University of London, London, United Kingdom.

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http://dx.doi.org/10.1161/CIRCRESAHA.113.300350	DOI Listing

March 2013

Entpd5 is essential for skeletal mineralization and regulates phosphate homeostasis in zebrafish.

Authors:

Leonie F A Huitema Alexander Apschner Ive Logister Kirsten M Spoorendonk Jeroen Bussmann Chrissy L Hammond Stefan Schulte-Merker

Proc Natl Acad Sci U S A 2012 Dec 12;109(52):21372-7. Epub 2012 Dec 12.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Centre Utrecht, 3584 CT, Utrecht, The Netherlands.

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http://dx.doi.org/10.1073/pnas.1214231110	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535636	PMC

December 2012

Swim-training changes the spatio-temporal dynamics of skeletogenesis in zebrafish larvae (Danio rerio).

Authors:

Ansa W Fiaz Karen M Léon-Kloosterziel Gerrit Gort Stefan Schulte-Merker Johan L van Leeuwen Sander Kranenbarg

PLoS One 2012 18;7(4):e34072. Epub 2012 Apr 18.

Experimental Zoology Group, Department of Animal Sciences, Wageningen University and Research Centre, Wageningen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0034072	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329525	PMC

November 2012

Macrophage-stimulating protein and calcium homeostasis in zebrafish.

Authors:

Leonie F A Huitema Jörg Renn Ive Logister Jerilyn K Gray Susan E Waltz Gert Flik Stefan Schulte-Merker

FASEB J 2012 Oct 11;26(10):4092-101. Epub 2012 Jul 11.

Hubrecht Institute, KNAW and University Medical Centre Utrecht, Uppsalalaan 8, 3584CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1096/fj.11-202663	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050368	PMC

October 2012

E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1.

Authors:

Bart G M W Weijts Walbert J Bakker Peter W A Cornelissen Kuo-Hsuan Liang Frank H Schaftenaar Bart Westendorp Charlotte A C M T de Wolf Maya Paciejewska Colinda L G J Scheele Lindsey Kent Gustavo Leone Stefan Schulte-Merker Alain de Bruin

EMBO J 2012 Oct 17;31(19):3871-84. Epub 2012 Aug 17.

Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/emboj.2012.231	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463843	PMC

October 2012

Apelin enhances cardiac neovascularization after myocardial infarction by recruiting aplnr+ circulating cells.

Authors:

Dennie Tempel Martine de Boer Elza D van Deel Remco A Haasdijk Dirk J Duncker Caroline Cheng Stefan Schulte-Merker Henricus J Duckers

Circ Res 2012 Aug 2;111(5):585-98. Epub 2012 Jul 2.

FESC, Molecular Cardiology Laboratory, Ee2389a, Thoraxcenter Rotterdam, Erasmus University Medical Center, 's-Gravendijkwal 230, 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1161/CIRCRESAHA.111.262097	DOI Listing

August 2012

Hedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish.

Authors:

Robert N Wilkinson Marco J Koudijs Roger K Patient Philip W Ingham Stefan Schulte-Merker Fredericus J M van Eeden

Blood 2012 Jul 5;120(2):477-88. Epub 2012 Jun 5.

MRC Centre for Developmental and Biomedical Genetics, University of Sheffield, Sheffield, United Kingdom.

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http://dx.doi.org/10.1182/blood-2011-10-383729	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833038	PMC

July 2012

Endothelial cell-specific FGD5 involvement in vascular pruning defines neovessel fate in mice.

Authors:

Caroline Cheng Remco Haasdijk Dennie Tempel Esther H M van de Kamp Robert Herpers Frank Bos Wijnand K Den Dekker Lau A J Blonden Renate de Jong Petra E Bürgisser Ihsan Chrifi Erik A L Biessen Stefanie Dimmeler Stefan Schulte-Merker Henricus J Duckers

Circulation 2012 Jun 1;125(25):3142-58. Epub 2012 Jun 1.

Molecular Cardiology Laboratory, Ee2389a, Thoraxcenter, Erasmus University Medical Center, Gravendijkwal 230, 3015 GE Rotterdam, Netherlands.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.111.064030	DOI Listing

June 2012

Zebrafish prox1b mutants develop a lymphatic vasculature, and prox1b does not specifically mark lymphatic endothelial cells.

Authors:

Shijie Tao Merlijn Witte Robert J Bryson-Richardson Peter D Currie Benjamin M Hogan Stefan Schulte-Merker

PLoS One 2011 28;6(12):e28934. Epub 2011 Dec 28.

Hubrecht Institute-Royal Netherlands Academy of Arts and Sciences and University Medical Centre, Utrecht, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0028934	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247213	PMC

May 2012

Mutations in KIF11 cause autosomal-dominant microcephaly variably associated with congenital lymphedema and chorioretinopathy.

Am J Hum Genet 2012 Feb 26;90(2):356-62. Epub 2012 Jan 26.

Medical Genetics Unit, Biomedical Sciences, St. George's University of London, UK.

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http://dx.doi.org/10.1016/j.ajhg.2011.12.018	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276660	PMC

February 2012

A zebrafish model for VHL and hypoxia signaling.

Authors:

Ellen van Rooijen Kirankumar Santhakumar Ive Logister Emile Voest Stefan Schulte-Merker Rachel Giles Fredericus van Eeden

Methods Cell Biol 2011 ;105:163-90

Department of Medical Oncology, University Medical Center, Universiteitsweg 100, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/B978-0-12-381320-6.00007-2	DOI Listing

January 2012

Zebrafish provides a novel model for lymphatic vascular research.

Authors:

Terhi Karpanen Stefan Schulte-Merker

Methods Cell Biol 2011 ;105:223-38

Hubrecht Institute - KNAWand University Medical Center Utrecht, Uppsalalaan 8, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/B978-0-12-381320-6.00009-6	DOI Listing

January 2012

Not all bones are created equal - using zebrafish and other teleost species in osteogenesis research.

Authors:

Alexander Apschner Stefan Schulte-Merker P Eckhard Witten

Methods Cell Biol 2011 ;105:239-55

Hubrecht Institute-KNAW & UMC Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/B978-0-12-381320-6.00010-2	DOI Listing

January 2012

Rapid BAC selection for tol2-mediated transgenesis in zebrafish.

Authors:

Jeroen Bussmann Stefan Schulte-Merker

Development 2011 Oct 24;138(19):4327-32. Epub 2011 Aug 24.

Hubrecht Institute - KNAW and Utrecht Medical Center, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.

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http://dx.doi.org/10.1242/dev.068080	DOI Listing

October 2011

Trpv5/6 is vital for epithelial calcium uptake and bone formation.

Authors:

Jo Vanoevelen Annelies Janssens Leonie F A Huitema Christina L Hammond Juriaan R Metz Gert Flik Thomas Voets Stefan Schulte-Merker

FASEB J 2011 Sep 13;25(9):3197-207. Epub 2011 Jun 13.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Centre, Utrecht, The Netherlands.

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http://dx.doi.org/10.1096/fj.11-183145	DOI Listing

September 2011

Ets2 determines the inflammatory state of endothelial cells in advanced atherosclerotic lesions.

Authors:

Caroline Cheng Dennie Tempel Wijnand K Den Dekker Remco Haasdijk Ihsan Chrifi Frank L Bos Kim Wagtmans Esther H van de Kamp Lau Blonden Erik A L Biessen Frans Moll Gerard Pasterkamp Patrick W Serruys Stefan Schulte-Merker Henricus J Duckers

Circ Res 2011 Aug 23;109(4):382-95. Epub 2011 Jun 23.

Molecular Cardiology Laboratory, Experimental Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1161/CIRCRESAHA.111.243444	DOI Listing

August 2011

CCBE1 is essential for mammalian lymphatic vascular development and enhances the lymphangiogenic effect of vascular endothelial growth factor-C in vivo.

Authors:

Frank L Bos Maresa Caunt Josi Peterson-Maduro Lara Planas-Paz Joe Kowalski Terhi Karpanen Andreas van Impel Raymond Tong James A Ernst Jeroen Korving Johan H van Es Eckhard Lammert Henricus J Duckers Stefan Schulte-Merker

Circ Res 2011 Aug 21;109(5):486-91. Epub 2011 Jul 21.

Hubrecht Institute-KNAW, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1161/CIRCRESAHA.111.250738	DOI Listing

August 2011

MicroRNA-24 regulates vascularity after myocardial infarction.

Circulation 2011 Aug 25;124(6):720-30. Epub 2011 Jul 25.

Hannover Medical School, Institute for Molecular and Translational Therapeutic Strategies, Hannover, Germany.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.111.039008	DOI Listing

August 2011

Flt1 acts as a negative regulator of tip cell formation and branching morphogenesis in the zebrafish embryo.

Authors:

Janna Krueger Dong Liu Katja Scholz Anja Zimmer Yu Shi Christian Klein Arndt Siekmann Stefan Schulte-Merker Melissa Cudmore Asif Ahmed Ferdinand le Noble

Development 2011 May;138(10):2111-20

Department of Angiogenesis and Cardiovascular Pathology, Max-Delbrueck Center for Molecular Medicine, D13125 Berlin, Germany.

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http://dx.doi.org/10.1242/dev.063933	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082310	PMC

May 2011

Bone regenerates via dedifferentiation of osteoblasts in the zebrafish fin.

Authors:

Franziska Knopf Christina Hammond Avinash Chekuru Thomas Kurth Stefan Hans Christopher W Weber Gina Mahatma Shannon Fisher Michael Brand Stefan Schulte-Merker Gilbert Weidinger

Dev Cell 2011 May;20(5):713-24

Biotechnology Center and Center for Regenerative Therapies, University of Technology Dresden, Tatzberg 47-49, 01307 Dresden, Germany.

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http://dx.doi.org/10.1016/j.devcel.2011.04.014	DOI Listing

May 2011

Lymphatic vascular morphogenesis in development, physiology, and disease.

Authors:

Stefan Schulte-Merker Amélie Sabine Tatiana V Petrova

J Cell Biol 2011 May;193(4):607-18

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, and University Medical Centre, 3584 CT Utrecht, Netherlands.

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http://www.jcb.org/lookup/doi/10.1083/jcb.201012094	Publisher Site
http://dx.doi.org/10.1083/jcb.201012094	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166860	PMC

May 2011

Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22.

Authors:

Evangelos Evangelou Ana M Valdes Hanneke J M Kerkhof Unnur Styrkarsdottir Yanyan Zhu Ingrid Meulenbelt Rik J Lories Fotini B Karassa Przemko Tylzanowski Steffan D Bos Toru Akune Nigel K Arden Andrew Carr Kay Chapman L Adrienne Cupples Jin Dai Panos Deloukas Michael Doherty Sally Doherty Gunnar Engstrom Antonio Gonzalez Bjarni V Halldorsson Christina L Hammond Deborah J Hart Hafdis Helgadottir Albert Hofman Shiro Ikegawa Thorvaldur Ingvarsson Qing Jiang Helgi Jonsson Jaakko Kaprio Hiroshi Kawaguchi Kalle Kisand Margreet Kloppenburg Urho M Kujala L Stefan Lohmander John Loughlin Frank P Luyten Akihiko Mabuchi Andrew McCaskie Masahiro Nakajima Peter M Nilsson Nao Nishida William E R Ollier Kalliope Panoutsopoulou Tom van de Putte Stuart H Ralston Fernado Rivadeneira Janna Saarela Stefan Schulte-Merker Dongquan Shi P Eline Slagboom Akihiro Sudo Agu Tamm Ann Tamm Gudmar Thorleifsson Unnur Thorsteinsdottir Aspasia Tsezou Gillian A Wallis J Mark Wilkinson Noriko Yoshimura Eleftheria Zeggini Guangju Zhai Feng Zhang Ingileif Jonsdottir Andre G Uitterlinden David T Felson Joyce B van Meurs Kari Stefansson John P A Ioannidis Timothy D Spector

Ann Rheum Dis 2011 Feb 10;70(2):349-55. Epub 2010 Nov 10.

Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece.

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http://dx.doi.org/10.1136/ard.2010.132787	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615180	PMC

February 2011

Zebrafish Tie-2 shares a redundant role with Tie-1 in heart development and regulates vessel integrity.

Authors:

Evisa Gjini Liesbeth H Hekking Axel Küchler Pipsa Saharinen Erno Wienholds Jan-Andries Post Kari Alitalo Stefan Schulte-Merker

Dis Model Mech 2011 Jan 2;4(1):57-66. Epub 2010 Nov 2.

Hubrecht Institute-KNAW and University Medical Centre, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1242/dmm.005033	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014345	PMC

January 2011

Role of synectin in lymphatic development in zebrafish and frogs.

Authors:

Karlien Hermans Filip Claes Wouter Vandevelde Wei Zheng Ilse Geudens Fabrizio Orsenigo Frederik De Smet Evisa Gjini Kristof Anthonis Bin Ren Dontcho Kerjaschki Monica Autiero Annelii Ny Michael Simons Mieke Dewerchin Stefan Schulte-Merker Elisabetta Dejana Kari Alitalo Peter Carmeliet

Blood 2010 Oct 14;116(17):3356-66. Epub 2010 Jul 14.

Vesalius Research Center, Vlaams Iustituut voor Biotechnologie, Katholieke Universiteit Leuven, Campus Gasthuisberg, Herestraat 49, Leuven, Belgium.

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http://www.bloodjournal.org/content/116/17/3356.full.pdf	Web Search
http://www.bloodjournal.org/cgi/doi/10.1182/blood-2009-11-25	Publisher Site
http://dx.doi.org/10.1182/blood-2009-11-254557	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490102	PMC

October 2010

Control of endothelial sprouting by a Tel-CtBP complex.

Authors:

M Guy Roukens Mariam Alloul-Ramdhani Bart Baan Kazuki Kobayashi Josi Peterson-Maduro Hans van Dam Stefan Schulte-Merker David A Baker

Nat Cell Biol 2010 Oct 12;12(10):933-42. Epub 2010 Sep 12.

Leiden University Medical Center (LUMC), Section of Growth Control and Transcription, Department of Molecular Cell Biology, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1038/ncb2096	DOI Listing

October 2010

Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting.

Authors:

Lars Jakobsson Claudio A Franco Katie Bentley Russell T Collins Bas Ponsioen Irene M Aspalter Ian Rosewell Marta Busse Gavin Thurston Alexander Medvinsky Stefan Schulte-Merker Holger Gerhardt

Nat Cell Biol 2010 Oct 26;12(10):943-53. Epub 2010 Sep 26.

Vascular Biology Laboratory, London Research Institute, Cancer Research UK, 44 Lincoln's Inn Fields, London, WC2A 3PX, UK.

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http://pbsb.med.cornell.edu/pdfs/nature_jakobsson.pdf	Web Search
http://www.nature.com/doifinder/10.1038/ncb2103	Publisher Site
http://dx.doi.org/10.1038/ncb2103	DOI Listing

October 2010

von Hippel-Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafish.

Authors:

Ellen van Rooijen Emile E Voest Ive Logister Jeroen Bussmann Jeroen Korving Fredericus J van Eeden Rachel H Giles Stefan Schulte-Merker

Dis Model Mech 2010 May-Jun;3(5-6):343-53. Epub 2010 Mar 24.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1242/dmm.004036	DOI Listing

September 2010

Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish.

Arterioscler Thromb Vasc Biol 2010 Sep 13;30(9):1695-702. Epub 2010 May 13.

Vesalius Research Center, VIB, Leuven, Belgium.

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http://dx.doi.org/10.1161/ATVBAHA.110.203034	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497575	PMC

September 2010

Arteries provide essential guidance cues for lymphatic endothelial cells in the zebrafish trunk.

Authors:

Jeroen Bussmann Frank L Bos Akihiro Urasaki Koichi Kawakami Henricus J Duckers Stefan Schulte-Merker

Development 2010 Aug 7;137(16):2653-7. Epub 2010 Jul 7.

Hubrecht Institute-KNAW and University Medical Centre, Utrecht, the Netherlands.

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http://dx.doi.org/10.1242/dev.048207	DOI Listing

August 2010

miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo.

Authors:

Deena M Leslie Pedrioli Terhi Karpanen Vasilios Dabouras Giorgia Jurisic Glenn van de Hoek Jay W Shin Daniela Marino Roland E Kälin Sebastian Leidel Paolo Cinelli Stefan Schulte-Merker André W Brändli Michael Detmar

Mol Cell Biol 2010 Jul 17;30(14):3620-34. Epub 2010 May 17.

Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zürich, Wolfgang-Pauli-Str. 10, HCI H303, CH-8093 Zürich, Switzerland.

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http://dx.doi.org/10.1128/MCB.00185-10	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897549	PMC

July 2010

Two populations of endochondral osteoblasts with differential sensitivity to Hedgehog signalling.

Authors:

Christina Lindsey Hammond Stefan Schulte-Merker

Development 2009 Dec;136(23):3991-4000

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences & University Medical Centre, 3584CT Utrecht, The Netherlands.

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http://dev.biologists.org/cgi/doi/10.1242/dev.042150	Publisher Site
http://dx.doi.org/10.1242/dev.042150	DOI Listing

December 2009

Vegfc/Flt4 signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries.

Authors:

Benjamin M Hogan Robert Herpers Merlijn Witte Hanna Heloterä Kari Alitalo Henricus J Duckers Stefan Schulte-Merker

Development 2009 Dec;136(23):4001-9

Hubrecht Institute-KNAW & University Medical Centre, Utrecht, and Centre for Biomedical Genetics, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1242/dev.039990	DOI Listing

December 2009

Mutations in CCBE1 cause generalized lymph vessel dysplasia in humans.

Authors:

Marielle Alders Benjamin M Hogan Evisa Gjini Faranak Salehi Lihadh Al-Gazali Eric A Hennekam Eva E Holmberg Marcel M A M Mannens Margot F Mulder G Johan A Offerhaus Trine E Prescott Eelco J Schroor Joke B G M Verheij Merlijn Witte Petra J Zwijnenburg Mikka Vikkula Stefan Schulte-Merker Raoul C Hennekam

Nat Genet 2009 Dec;41(12):1272-4

Department of Clinical Genetics, Academic Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/ng.484	DOI Listing

December 2009

Zebrafish development and regeneration: new tools for biomedical research.

Int J Dev Biol 2009 ;53(5-6):835-50

Institute of Biology, Dept. Integrative Zoology, University of Leiden, The Netherlands.

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http://dx.doi.org/10.1387/ijdb.082615sb	DOI Listing

September 2009

Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemia.

Authors:

Ellen van Rooijen Emile E Voest Ive Logister Jeroen Korving Thorsten Schwerte Stefan Schulte-Merker Rachel H Giles Fredericus J van Eeden

Blood 2009 Jun 20;113(25):6449-60. Epub 2009 Mar 20.

Department of Medical Oncology, University Medical Center, Utrecht, The Netherlands.

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http://dx.doi.org/10.1182/blood-2008-07-167890	DOI Listing

June 2009

Functional analyses of human and zebrafish 18-amino acid in-frame deletion pave the way for domain mapping of the cerebral cavernous malformation 3 protein.

Authors:

Katrin Voss Sonja Stahl Benjamin M Hogan Joerg Reinders Elisa Schleider Stefan Schulte-Merker Ute Felbor

Hum Mutat 2009 Jun;30(6):1003-11

Department of Human Genetics, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1002/humu.20996	DOI Listing

June 2009

Ccbe1 is required for embryonic lymphangiogenesis and venous sprouting.

Authors:

Benjamin M Hogan Frank L Bos Jeroen Bussmann Merlijn Witte Neil C Chi Henricus J Duckers Stefan Schulte-Merker

Nat Genet 2009 Apr 15;41(4):396-8. Epub 2009 Mar 15.

Hubrecht Institute-KNAW & University Medical Centre, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/ng.321	DOI Listing

April 2009

Retinoic acid and Cyp26b1 are critical regulators of osteogenesis in the axial skeleton.

Authors:

Kirsten M Spoorendonk Josi Peterson-Maduro Jörg Renn Torsten Trowe Sander Kranenbarg Christoph Winkler Stefan Schulte-Merker

Development 2008 Nov 16;135(22):3765-74. Epub 2008 Oct 16.

Hubrecht Institute, University Medical Centre Utrecht, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1242/dev.024034	DOI Listing

November 2008

ccm1 cell autonomously regulates endothelial cellular morphogenesis and vascular tubulogenesis in zebrafish.

Authors:

Benjamin M Hogan Jeroen Bussmann Hartwig Wolburg Stefan Schulte-Merker

Hum Mol Genet 2008 Aug 10;17(16):2424-32. Epub 2008 May 10.

Hubrecht Institute-KNAW and University Medical Centre Utrecht, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/hmg/ddn142	DOI Listing

August 2008

LRRC50, a conserved ciliary protein implicated in polycystic kidney disease.

Authors:

Ellen van Rooijen Rachel H Giles Emile E Voest Carina van Rooijen Stefan Schulte-Merker Freek J van Eeden

J Am Soc Nephrol 2008 Jun 2;19(6):1128-38. Epub 2008 Apr 2.

Hubrecht Institute, Developmental Biology and Stem Cell Research, University Medical Center Utrecht, Utrecht, Netherlands.

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http://dx.doi.org/10.1681/ASN.2007080917	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396934	PMC

June 2008

Zebrafish VEGF receptors: a guideline to nomenclature.

Authors:

Jeroen Bussmann Nathan Lawson Leonard Zon Stefan Schulte-Merker

PLoS Genet 2008 May 30;4(5):e1000064. Epub 2008 May 30.

Hubrecht Laboratory (NIOB-KNAW NIOB), Utrecht, The Netherlands.

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http://dx.doi.org/10.1371/journal.pgen.1000064	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367445	PMC

May 2008

Rotation and asymmetric development of the zebrafish heart requires directed migration of cardiac progenitor cells.

Authors:

Kelly A Smith Sonja Chocron Sophia von der Hardt Emma de Pater Alexander Soufan Jeroen Bussmann Stefan Schulte-Merker Matthias Hammerschmidt Jeroen Bakkers

Dev Cell 2008 Feb;14(2):287-97

Hubrecht Institute for Developmental Biology and Stem Cell Research, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.devcel.2007.11.015	DOI Listing

February 2008

Redundant roles for sox7 and sox18 in arteriovenous specification in zebrafish.

Authors:

Robert Herpers Esther van de Kamp Henricus J Duckers Stefan Schulte-Merker

Circ Res 2008 Jan 21;102(1):12-5. Epub 2007 Nov 21.

Hubrecht Institute, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1161/CIRCRESAHA.107.166066	DOI Listing

January 2008

Early endocardial morphogenesis requires Scl/Tal1.

Authors:

Jeroen Bussmann Jeroen Bakkers Stefan Schulte-Merker

PLoS Genet 2007 Aug 9;3(8):e140. Epub 2007 Jul 9.

Hubrecht Institute, Utrecht, The Netherlands.

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http://dx.plos.org/10.1371/journal.pgen.0030140	Publisher Site
http://dx.doi.org/10.1371/journal.pgen.0030140	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1950955	PMC

August 2007

Development of the zebrafish lymphatic system requires VEGFC signaling.

Authors:

Axel M Küchler Evisa Gjini Josi Peterson-Maduro Belinda Cancilla Hartwig Wolburg Stefan Schulte-Merker

Curr Biol 2006 Jun;16(12):1244-8

Exelixis, Inc., 170 Harbor Way, South San Francisco, California 94083, USA.

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http://dx.doi.org/10.1016/j.cub.2006.05.026	DOI Listing

June 2006

tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors.

Authors:

Stéphane Berghmans Ryan D Murphey Erno Wienholds Donna Neuberg Jeffery L Kutok Christopher D M Fletcher John P Morris Ting Xi Liu Stefan Schulte-Merker John P Kanki Ronald Plasterk Leonard I Zon A Thomas Look

Proc Natl Acad Sci U S A 2005 Jan 3;102(2):407-12. Epub 2005 Jan 3.

Department of Pediatric Oncology, Dana-Farber Cancer Institute, and Division of Hematology/Oncology, Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0406252102	Publisher Site
http://dx.doi.org/10.1073/pnas.0406252102	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC544293	PMC