Stefan Pfister

Stefan Pfister

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Stefan Pfister

Stefan Pfister

Publications by authors named "Stefan Pfister"

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Genome-wide analysis of acute leukemia and clonally related histiocytic sarcoma in a series of three pediatric patients.

Pediatr Blood Cancer 2019 Nov 18:e28074. Epub 2019 Nov 18.

Division of Pediatric Stem Cell Transplant and Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/pbc.28074DOI Listing
November 2019

RF_Purify: a novel tool for comprehensive analysis of tumor-purity in methylation array data based on random forest regression.

BMC Bioinformatics 2019 Aug 16;20(1):428. Epub 2019 Aug 16.

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1186/s12859-019-3014-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697926PMC
August 2019

EORTC SPECTA-AYA: A unique molecular profiling platform for adolescents and young adults with cancer in Europe.

Int J Cancer 2019 Aug 29. Epub 2019 Aug 29.

Division of Cancer Sciences, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1002/ijc.32651DOI Listing
August 2019

Brainstem biopsy in pediatric diffuse intrinsic pontine glioma in the era of precision medicine: the INFORM study experience.

Eur J Cancer 2019 Jun 22;114:27-35. Epub 2019 Apr 22.

Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Pediatric Oncology, Hematology & Immunology, Heidelberg University Hospital, Heidelberg, Germany; Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09598049193022
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http://dx.doi.org/10.1016/j.ejca.2019.03.019DOI Listing
June 2019

Prevalence and quantification of contamination of knitted cotton outer gloves during hip and knee arthroplasty surgery.

Arch Orthop Trauma Surg 2019 Apr 7;139(4):451-459. Epub 2018 Nov 7.

Division of Orthopaedics and Traumatology, Cantonal Hospital Winterthur, Brauerstrasse 15, P.O. Box 834, 8401, Winterthur, Switzerland.

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http://link.springer.com/10.1007/s00402-018-3061-3
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http://dx.doi.org/10.1007/s00402-018-3061-3DOI Listing
April 2019

cIMPACT-NOW update 4: diffuse gliomas characterized by MYB, MYBL1, or FGFR1 alterations or BRAF mutation.

Acta Neuropathol 2019 Apr 8;137(4):683-687. Epub 2019 Mar 8.

Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1007/s00401-019-01987-0DOI Listing
April 2019

Medulloblastoma.

Nat Rev Dis Primers 2019 02 14;5(1):11. Epub 2019 Feb 14.

Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41572-019-0063-6DOI Listing
February 2019

Methylation array profiling of adult brain tumours: diagnostic outcomes in a large, single centre.

Acta Neuropathol Commun 2019 02 20;7(1):24. Epub 2019 Feb 20.

Division of Neuropathology, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, Queen Square, London, WC1N 3BG, UK.

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https://actaneurocomms.biomedcentral.com/articles/10.1186/s4
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http://dx.doi.org/10.1186/s40478-019-0668-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381711PMC
February 2019

Translating genomic medicine to the clinic: challenges and opportunities.

Genome Med 2019 02 22;11(1). Epub 2019 Feb 22.

Centre for Personalised Medicine, Linköping University, Linköping, Sweden.

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http://dx.doi.org/10.1186/s13073-019-0622-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385380PMC
February 2019

InTAD: chromosome conformation guided analysis of enhancer target genes.

BMC Bioinformatics 2019 Jan 31;20(1):60. Epub 2019 Jan 31.

Department of Medicine, Division of Medical Genetics, University of California San Diego (UCSD), San Diego, USA.

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https://bmcbioinformatics.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/s12859-019-2655-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357397PMC
January 2019

Extensive Molecular and Clinical Heterogeneity in Patients With Histologically Diagnosed CNS-PNET Treated as a Single Entity: A Report From the Children's Oncology Group Randomized ACNS0332 Trial.

J Clin Oncol 2018 Oct 17:JCO2017764720. Epub 2018 Oct 17.

Eugene I. Hwang and Roger J. Packer, Children's National Medical Center, Washington, DC; Marcel Kool, Lukas Chavez, Sebastian Brabetz, David T.W. Jones, and Stefan M. Pfister, German Cancer Research Center; David Capper, Andreas von Deimling, and Stefan M. Pfister, University Hospital Heidelberg; Stefan M. Pfister, National Center for Tumor Diseases, Heidelberg; David Capper, Charité Medical University, Berlin, Germany; Peter C. Burger, Johns Hopkins University, Baltimore, MD; Chris Williams-Hughes, Children's Oncology Group, Littleton, CO; Catherine Billups, Yimei Li, and Amar Gajjar, St Jude Children's Research Hospital, Memphis, TN; Linda Heier, Weill Cornell Medical College, New York, NY; Alok Jaju, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; Jeff Michalski, Washington University School of Medicine, St. Louis, MO; Sarah Leary and James M. Olson, Seattle Children's Hospital and Research Institute; Sarah Leary and James M. Olson, Fred Hutchinson Cancer Research Center, Seattle, WA; Tianni Zhou, California State University, Long Beach, Long Beach, CA; Maryam Fouladi, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; and Ian F. Pollack, Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1200/JCO.2017.76.4720DOI Listing
October 2018

EGFL7 enhances surface expression of integrin αβ to promote angiogenesis in malignant brain tumors.

EMBO Mol Med 2018 09;10(9)

Molecular Signal Transduction Laboratories, Institute for Microscopic Anatomy and Neurobiology, Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn), University Medical Center of the Johannes Gutenberg University, Mainz, Germany

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http://dx.doi.org/10.15252/emmm.201708420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127886PMC
September 2018

Molecular characterization of medulloblastomas with extensive nodularity (MBEN).

Acta Neuropathol 2018 08 22;136(2):303-313. Epub 2018 Mar 22.

Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00401-018-1840-0DOI Listing
August 2018

Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.

J Clin Oncol 2018 07 10;36(19):1963-1972. Epub 2018 May 10.

Lindsey M. Hoffman and Nicholas K. Foreman, University of Colorado Denver; Lindsey M. Hoffman and Nicholas K. Foreman, Children's Hospital Colorado, Aurora, CO; Sophie E.M. Veldhuijzen van Zanten, Esther Hulleman, Gertjan J.L. Kaspers, Esther Sanchez, and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; William P. Vandertop, Academy of Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Niclas Colditz, Marion Hoffmann, Brigitte Bison, Monika Warmuth-Metz, and Christof M. Kramm, University Medical Center Goettingen, Goettingen; Torsten Pietsch and Gerrit H. Gielen, University of Bonn Medical Center, Bonn; David T.W. Jones, Dominik Sturm, Stefan M. Pfister, and Elke Pfaff, German Cancer Research Center, Hopp-Children's Cancer Center at the Nationale Centrum für Tumorerkrankungen Heidelberg, and German Consortium for Translational Cancer Research; Dominik Sturm, Stefan M. Pfister, and Elke Pfaff, Heidelberg University Hospital, Heidelberg, Germany; Joshua Baugh, Brooklyn Chaney, Adam Lane, Christine Fuller, Nancy Yanez Escorza, Renee Doughman, Rachid Drissi, James Leach, Blaise Jones, and Maryam Fouladi, Cincinnati Children's Hospital Medical Center, Cincinnati; Emmett Broxson, Wright State University and The Children's Medical Center, Dayton, OH; Lili Miles, Nemours Children's Hospital, Orlando, FL; Cynthia Hawkins, Ute Bartels, and Eric Bouffet, The Hospital for Sick Children, Toronto, Ontario; Anne Sophie Carret, Centre Hospitalier Universitaire Sainte-Justine; Nada Jabado, McGill University, Montreal, Quebec, Canada; Stewart Goldman, Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, IL; Sarah Leary, Seattle Children's Hospital, University of Washington and Fred Hutchinson Cancer Research Center, Seattle, WA; Roger Packer, Children's National Health System; Javad Nazarian, Children's National Medical Center, Washington, DC; Katherine E. Warren, National Cancer Institute, Bethesda, MD; Alberto Broniscer, St Jude Children's Research Hospital, Memphis, TN; Mark W. Kieran, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA; Jane Minturn, Children's Hospital of Philadelphia and The Perelman School of Medicine at the University of Pennsylvania, Philadelphia; Melanie Comito, The Pennsylvania State University, Hershey, PA; Chie-Schin Shih, Indiana University, Indianapolis, IN; Soumen Khatua, The University of Texas MD Anderson Cancer Center; Murali Chintagumpala, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, TX; Timothy Hassall, Lady Cilento Children's Hospital, Brisbane, Queensland; David S. Ziegler, Kids Cancer Centre, Sydney Children's Hospital, Randwick; David S. Ziegler, University of New South Wales, Sydney, New South Wales; Nicholas Gottardo and Hetal Dholaria, Princess Margaret Hospital for Children, Perth, Western Australia, Australia; Martin Benesch, Medical University of Graz, Graz, Austria; Nathalie Boddaert. Stephanie Puget, and Raphaël Calmon, Hôpital Necker Enfants Malades; Pascale Varlet, Hôpital Sainte-Anne, Université Paris V Descartes, Sorbonne Paris Cité, Paris; Géraldine Giraud, David Castel, and Jacques Grill, Gustave Roussy, Université Paris-Sud, Université Paris-Saclay, Villejuif, France; Géraldine Giraud, Uppsala University, Uppsala, Sweden; Chris Jones, The Institute of Cancer Research, Sutton; Darren Hargrave, Great Ormond Street Hospital, London; Guirish A. Solanki, Birmingham Women's and Children's Hospital, Birmingham; Simon Bailey, Great North Children's Hospital, Victoria Wing, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom; Piergiorgio Modena and Marzia Giagnacovo, Sant' Anna Como General Hospital, Como; Manila Antonelli, Sapienza University of Rome, Rome; Veronica Biassoni and Maura Massimino, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale dei Tumori, Milan, Italy; Nicolas U. Gerber and Michael A. Grotzer, University Children's Hospital of Zurich, Zurich; André O. von Bueren, University Hospital of Geneva and University of Geneva, Geneva, Switzerland; and Filip Jadrijevic Cvrlje and Gertjan J.L. Kaspers, Children's Hospital Zagreb, Zagreb, Croatia.

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http://dx.doi.org/10.1200/JCO.2017.75.9308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075859PMC
July 2018

Author Correction: The landscape of genomic alterations across childhood cancers.

Nature 2018 07;559(7714):E10

Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41586-018-0167-2DOI Listing
July 2018

Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma.

Cell Rep 2018 07;24(2):463-478.e5

Cellular and Molecular Biology Graduate Program, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Gilbert Family Neurofibromatosis Institute, Children's National Medical Center, Washington, DC 20010, USA; Center for Cancer and Immunology Research, Children's National Medical Center, Washington, DC 20010, USA; Center for Neuroscience Research, Children's National Medical Center, Washington, DC 20010, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.06.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116735PMC
July 2018

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.

Lancet Oncol 2018 06 9;19(6):785-798. Epub 2018 May 9.

Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany; Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; Hopp Children's Cancer Center at the NCT Heidelberg, Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045183024
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http://dx.doi.org/10.1016/S1470-2045(18)30242-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984248PMC
June 2018

Proteomic analysis of Medulloblastoma reveals functional biology with translational potential.

Acta Neuropathol Commun 2018 06 7;6(1):48. Epub 2018 Jun 7.

Center for Cancer and Immunology Research, Children's Research Institute, Children's National Health System, Washington, DC, USA.

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http://dx.doi.org/10.1186/s40478-018-0548-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992829PMC
June 2018

CRISPR-mediated Loss of Function Analysis in Cerebellar Granule Cells Using In Utero Electroporation-based Gene Transfer.

J Vis Exp 2018 06 9(136). Epub 2018 Jun 9.

Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ); Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), and German Cancer Consortium (DKTK);

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http://dx.doi.org/10.3791/57311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101645PMC
June 2018

A Mouse Ependymoma Model Provides Molecular Insights into Tumor Formation.

Cell Rep 2018 06;23(13):3699-3700

Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), 69120 Heidelberg, Germany; Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; Department of Pediatric Oncology, Hematology and Immunology, University Hospital, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.06.062DOI Listing
June 2018

Key Implications of Data Sharing in Pediatric Genomics.

JAMA Pediatr 2018 05;172(5):476-481

Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1001/jamapediatrics.2017.5500DOI Listing
May 2018

Systematic identification of suspected anthelmintic benzimidazole metabolites using LC-MS/MS.

J Pharm Biomed Anal 2018 Mar 28;151:151-158. Epub 2017 Dec 28.

Department of Clinical Pharmacology and Pharmacoepidemiology, Im Neuenheimer Feld 410, University Hospital Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.jpba.2017.12.056DOI Listing
March 2018

The landscape of genomic alterations across childhood cancers.

Nature 2018 03 28;555(7696):321-327. Epub 2018 Feb 28.

Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature25480DOI Listing
March 2018

DNA methylation-based classification of central nervous system tumours.

Authors:
David Capper David T W Jones Martin Sill Volker Hovestadt Daniel Schrimpf Dominik Sturm Christian Koelsche Felix Sahm Lukas Chavez David E Reuss Annekathrin Kratz Annika K Wefers Kristin Huang Kristian W Pajtler Leonille Schweizer Damian Stichel Adriana Olar Nils W Engel Kerstin Lindenberg Patrick N Harter Anne K Braczynski Karl H Plate Hildegard Dohmen Boyan K Garvalov Roland Coras Annett Hölsken Ekkehard Hewer Melanie Bewerunge-Hudler Matthias Schick Roger Fischer Rudi Beschorner Jens Schittenhelm Ori Staszewski Khalida Wani Pascale Varlet Melanie Pages Petra Temming Dietmar Lohmann Florian Selt Hendrik Witt Till Milde Olaf Witt Eleonora Aronica Felice Giangaspero Elisabeth Rushing Wolfram Scheurlen Christoph Geisenberger Fausto J Rodriguez Albert Becker Matthias Preusser Christine Haberler Rolf Bjerkvig Jane Cryan Michael Farrell Martina Deckert Jürgen Hench Stephan Frank Jonathan Serrano Kasthuri Kannan Aristotelis Tsirigos Wolfgang Brück Silvia Hofer Stefanie Brehmer Marcel Seiz-Rosenhagen Daniel Hänggi Volkmar Hans Stephanie Rozsnoki Jordan R Hansford Patricia Kohlhof Bjarne W Kristensen Matt Lechner Beatriz Lopes Christian Mawrin Ralf Ketter Andreas Kulozik Ziad Khatib Frank Heppner Arend Koch Anne Jouvet Catherine Keohane Helmut Mühleisen Wolf Mueller Ute Pohl Marco Prinz Axel Benner Marc Zapatka Nicholas G Gottardo Pablo Hernáiz Driever Christof M Kramm Hermann L Müller Stefan Rutkowski Katja von Hoff Michael C Frühwald Astrid Gnekow Gudrun Fleischhack Stephan Tippelt Gabriele Calaminus Camelia-Maria Monoranu Arie Perry Chris Jones Thomas S Jacques Bernhard Radlwimmer Marco Gessi Torsten Pietsch Johannes Schramm Gabriele Schackert Manfred Westphal Guido Reifenberger Pieter Wesseling Michael Weller Vincent Peter Collins Ingmar Blümcke Martin Bendszus Jürgen Debus Annie Huang Nada Jabado Paul A Northcott Werner Paulus Amar Gajjar Giles W Robinson Michael D Taylor Zane Jaunmuktane Marina Ryzhova Michael Platten Andreas Unterberg Wolfgang Wick Matthias A Karajannis Michel Mittelbronn Till Acker Christian Hartmann Kenneth Aldape Ulrich Schüller Rolf Buslei Peter Lichter Marcel Kool Christel Herold-Mende David W Ellison Martin Hasselblatt Matija Snuderl Sebastian Brandner Andrey Korshunov Andreas von Deimling Stefan M Pfister

Nature 2018 03 14;555(7697):469-474. Epub 2018 Mar 14.

Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature26000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093218PMC
March 2018

Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma.

Dev Cell 2018 03 15;44(6):709-724.e6. Epub 2018 Mar 15.

Center for Neuropathology, Ludwig-Maximilians-University, 81377 Munich, Germany; Research Institute Children's Cancer Center Hamburg, Martinistrasse 52, N63 (HPI), Hamburg 20251, Germany; Institute of Neuropathology, University Medical Center, Hamburg-Eppendorf, 20246 Hamburg, Germany; Department of Pediatric Hematology and Oncology, University Medical Center, Hamburg-Eppendorf, 20246 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2018.02.012DOI Listing
March 2018