Stefan Leucht

Stefan Leucht

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Stefan Leucht

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Second-generation antipsychotic drugs and short-term somatic serious adverse events: a systematic review and meta-analysis.

Lancet Psychiatry 2019 Jul 15. Epub 2019 Jul 15.

Department of Psychiatry and Psychotherapy, School of Medicine, Technical University of Munich, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/S2215-0366(19)30223-8DOI Listing
July 2019

Efficacy and tolerability of pharmacological and non-pharmacological interventions in older patients with major depressive disorder: A systematic review, pairwise and network meta-analysis.

Eur Neuropsychopharmacol 2019 Jul 18. Epub 2019 Jul 18.

Department of Psychiatry and Psychotherapy, Technical University of Munich, Klinikum rechts der Isar, Ismaningerstraße 22, 81675 Munich, Germany.

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http://dx.doi.org/10.1016/j.euroneuro.2019.07.130DOI Listing
July 2019

The controversy about cognitive behavioural therapy for schizophrenia.

World Psychiatry 2019 Jun;18(2):235-236

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, School of Medicine, Technical University Munich, Munich, Germany.

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http://dx.doi.org/10.1002/wps.20636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502403PMC
June 2019

Reduced striatal dopamine synthesis capacity in patients with schizophrenia during remission of positive symptoms.

Brain 2019 Jun;142(6):1813-1826

Department of Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1093/brain/awz093DOI Listing
June 2019

Evaluation of Differences in Individual Treatment Response in Schizophrenia Spectrum Disorders: A Meta-analysis.

JAMA Psychiatry 2019 Jun 3. Epub 2019 Jun 3.

Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, New York.

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http://dx.doi.org/10.1001/jamapsychiatry.2019.1530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547253PMC
June 2019

Disconnection of drug-response and placebo-response in acute-phase antipsychotic drug trials on schizophrenia? Meta-regression analysis.

Neuropsychopharmacology 2019 Jun 18. Epub 2019 Jun 18.

Psychiatric Institute, University of Illinois at Chicago (mc 912), 1601 W. Taylor Street, Chicago, IL, 60612, USA.

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http://dx.doi.org/10.1038/s41386-019-0440-6DOI Listing
June 2019

Specific Substantial Dysconnectivity in Schizophrenia: A Transdiagnostic Multimodal Meta-analysis of Resting-State Functional and Structural Magnetic Resonance Imaging Studies.

Biol Psychiatry 2019 Apr 11;85(7):573-583. Epub 2018 Dec 11.

Department of Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany; Neuroimaging Center at the Technische Universität München, Klinikum rechts der Isar, Technische Universität München, Munich, Germany; Department of Psychiatry, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1016/j.biopsych.2018.12.003DOI Listing
April 2019

Translating the BDI and BDI-II into the HAMD and vice versa with equipercentile linking.

Epidemiol Psychiatr Sci 2019 Mar 14:1-13. Epub 2019 Mar 14.

Department of Clinical, Neuro-, and Developmental Psychology,Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam,The Netherlands.

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http://dx.doi.org/10.1017/S2045796019000088DOI Listing
March 2019

Maximizing response to first-line antipsychotics in schizophrenia: a review focused on finding from meta-analysis.

Psychopharmacology (Berl) 2019 Feb 30;236(2):545-559. Epub 2018 Nov 30.

Department of Psychiatry, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1007/s00213-018-5133-zDOI Listing
February 2019

Efficient two-step multivariate random effects meta-analysis of individual participant data for longitudinal clinical trials using mixed effects models.

BMC Med Res Methodol 2019 02 14;19(1):33. Epub 2019 Feb 14.

Department of Health Promotion and Human Behavior, Kyoto University Graduate School of Medicine / School of Public Health, Kyoto, Japan.

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http://dx.doi.org/10.1186/s12874-019-0676-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376708PMC
February 2019

Fat Mass and Obesity-Related Gene Variants rs9939609 and rs7185735 are Associated with Second-Generation Antipsychotic-Induced Weight Gain.

Pharmacopsychiatry 2019 Jan 15;52(1):16-23. Epub 2018 Jan 15.

Institut für Klinische Chemie und Pathobiochemie, Klinikum rechts der Isar, Technischen Universität München, München, Germany.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-125392
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http://dx.doi.org/10.1055/s-0043-125392DOI Listing
January 2019

Efficacy, acceptability and tolerability of antipsychotics in patients with schizophrenia and comorbid substance use. A systematic review and meta-analysis.

Eur Neuropsychopharmacol 2019 01 22;29(1):32-45. Epub 2018 Nov 22.

Department of Psychiatry and Psychotherapy, Technical University of Munich, Klinikum rechts der Isar, Ismaningerstraße 22, 81675 Munich, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S0924977X183196
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http://dx.doi.org/10.1016/j.euroneuro.2018.11.1105DOI Listing
January 2019

Antipsychotic drugs for elderly patients with schizophrenia: A systematic review and meta-analysis.

Eur Neuropsychopharmacol 2018 12 20;28(12):1360-1370. Epub 2018 Sep 20.

Department of Psychiatry and Psychotherapy, Technical University of Munich, Klinikum rechts der Isar, Ismaningerstraße 22, 81675 Munich, Germany.

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http://dx.doi.org/10.1016/j.euroneuro.2018.09.007DOI Listing
December 2018

60 years of placebo-controlled antipsychotic drug trials in acute schizophrenia: Meta-regression of predictors of placebo response.

Schizophr Res 2018 11 24;201:315-323. Epub 2018 May 24.

Psychiatric Institute, University of Illinois at Chicago (MC 912), 1601 W. Taylor St., Chicago, IL 60612, USA; Maryland Psychiatric Research Center, Baltimore, MD, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09209964183026
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http://dx.doi.org/10.1016/j.schres.2018.05.009DOI Listing
November 2018

Antipsychotic drugs for patients with schizophrenia and predominant or prominent negative symptoms: a systematic review and meta-analysis.

Eur Arch Psychiatry Clin Neurosci 2018 Oct 24;268(7):625-639. Epub 2018 Jan 24.

Department of Psychiatry and Psychotherapy, Technical University of Munich, Klinikum rechts der Isar, Ismaningerstraße 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1007/s00406-018-0869-3DOI Listing
October 2018

Possibly no baseline severity effect for antidepressants versus placebo but for antipsychotics. Why?

Eur Arch Psychiatry Clin Neurosci 2018 Oct;268(7):621-623

Department of Health Promotion and Human Behavior, Graduate School of Medicine/School of Public Health, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1007/s00406-018-0940-0DOI Listing
October 2018

Second-generation antipsychotic drugs and short-term mortality: a systematic review and meta-analysis of placebo-controlled randomised controlled trials.

Lancet Psychiatry 2018 08 2;5(8):653-663. Epub 2018 Jul 2.

Department of Psychiatry and Psychotherapy, Technical University of Munich, Klinikum rechts der Isar, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/S2215-0366(18)30177-9DOI Listing
August 2018

How Many Patients With Schizophrenia Do Not Respond to Antipsychotic Drugs in the Short Term? An Analysis Based on Individual Patient Data From Randomized Controlled Trials.

Schizophr Bull 2018 Jul 2. Epub 2018 Jul 2.

Department of Psychiatry and Psychotherapy, Technische Universität München, Klinikum rechts der Isar, Ismaningerstr, Munich, Germany.

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http://dx.doi.org/10.1093/schbul/sby095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483567PMC
July 2018

Antidepressants might work for people with major depression: where do we go from here?

Lancet Psychiatry 2018 06 5;5(6):461-463. Epub 2018 Apr 5.

Department of Psychiatry, University of Oxford, Oxford, UK; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford OX3 7JX, UK.

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http://dx.doi.org/10.1016/S2215-0366(18)30133-0DOI Listing
June 2018

Efficacy, acceptability, and tolerability of antipsychotics in children and adolescents with schizophrenia: A network meta-analysis.

Eur Neuropsychopharmacol 2018 06 24;28(6):659-674. Epub 2018 May 24.

Department of Psychiatry and Psychotherapy, Technical University of Munich, Klinikum rechts der Isar, Ismaningerstraße 22, 81675 Munich, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S0924977X183007
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http://dx.doi.org/10.1016/j.euroneuro.2018.03.008DOI Listing
June 2018

Is there compelling evidence that schizophrenia long-term treatment guidelines should be changed?

Authors:
Stefan Leucht

World Psychiatry 2018 Jun;17(2):166-167

Department of Psychiatry and Psychotherapy, Technische Universität München Klinikum rechts der Isar, Munich, Germany.

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http://dx.doi.org/10.1002/wps.20520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980526PMC
June 2018

Increasing antipsychotic dose versus switching antipsychotic for non response in schizophrenia.

Cochrane Database Syst Rev 2018 05 11;5:CD011884. Epub 2018 May 11.

Klinik und Poliklinik für Psychiatrie und Psychotherapie, Technische Universität München Klinikum rechts der Isar, Ismaninger Straße 22, München, Germany, 81675.

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http://dx.doi.org/10.1002/14651858.CD011884.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494492PMC
May 2018

Increasing antipsychotic dose for non response in schizophrenia.

Cochrane Database Syst Rev 2018 05 11;5:CD011883. Epub 2018 May 11.

Klinik und Poliklinik für Psychiatrie und Psychotherapie, Technische Universität München Klinikum rechts der Isar, Ismaninger Straße 22, München, Germany, 81675.

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http://dx.doi.org/10.1002/14651858.CD011883.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494602PMC
May 2018

Enthusiasm and Skepticism About Using National Registers to Analyze Psychotropic Drug Outcomes.

JAMA Psychiatry 2018 Apr;75(4):314-315

Psychiatric Institute, University of Illinois, Chicago.

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http://dx.doi.org/10.1001/jamapsychiatry.2017.4704DOI Listing
April 2018

Dose equivalents for second generation long-acting injectable antipsychotics: The minimum effective dose method.

Schizophr Res 2018 03 21;193:23-28. Epub 2017 Jul 21.

Department of Psychiatry and Psychotherapy, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1016/j.schres.2017.07.033DOI Listing
March 2018

Psychological interventions for positive symptoms in schizophrenia: protocol for a network meta-analysis of randomised controlled trials.

BMJ Open 2018 03 14;8(3):e019280. Epub 2018 Mar 14.

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technischen Universitat Munchen, Munchen, Germany.

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http://dx.doi.org/10.1136/bmjopen-2017-019280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857696PMC
March 2018

Effects of Short-Term Exercise Interventions on Behavioral and Psychological Symptoms in Patients with Dementia: A Systematic Review.

J Alzheimers Dis 2017 ;55(4):1583-1594

Department of Geriatric Psychiatry and Psychotherapy, LVR-Hospital Cologne; Academic teaching hospital of the University of Cologne, Köln, Germany.

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http://dx.doi.org/10.3233/JAD-160683DOI Listing
February 2018

Is placebo response in antidepressant trials rising or not? A reanalysis of datasets to conclude this long-lasting controversy.

Evid Based Ment Health 2018 02 12;21(1):1-3. Epub 2018 Jan 12.

Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1136/eb-2017-102827DOI Listing
February 2018

Translating the HAM-D into the MADRS and vice versa with equipercentile linking.

J Affect Disord 2018 01 27;226:326-331. Epub 2017 Sep 27.

Allergan, USA.

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http://dx.doi.org/10.1016/j.jad.2017.09.042DOI Listing
January 2018

A novel approach to measuring response and remission in schizophrenia in clinical trials.

Schizophr Res 2017 12 15;190:123-128. Epub 2017 Mar 15.

Editor-in-Chief, International Journal of Mental Health & Addiction Consultant, Kuwait Center for Autism, Kuwait.

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http://dx.doi.org/10.1016/j.schres.2017.03.020DOI Listing
December 2017

Initial symptom severity of bipolar I disorder and the efficacy of olanzapine: a meta-analysis of individual participant data from five placebo-controlled studies.

Lancet Psychiatry 2017 11 19;4(11):859-867. Epub 2017 Sep 19.

Department of Psychiatry and Psychotherapy, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1016/S2215-0366(17)30331-0DOI Listing
November 2017

Sixty Years of Placebo-Controlled Antipsychotic Drug Trials in Acute Schizophrenia: Systematic Review, Bayesian Meta-Analysis, and Meta-Regression of Efficacy Predictors.

Am J Psychiatry 2017 10 25;174(10):927-942. Epub 2017 May 25.

From the Department of Psychiatry and Psychotherapy, Technische Universität München, Munich, Germany; the Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, U.K.; the Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece; the Institute of Social and Preventive Medicine. University of Bern, Bern, Switzerland; and the Psychiatric Institute, University of Illinois at Chicago, and the Maryland Psychiatric Research Center, Baltimore.

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http://dx.doi.org/10.1176/appi.ajp.2017.16121358DOI Listing
October 2017

The Prevalence of Mental Illness in Homeless People in Germany.

Dtsch Arztebl Int 2017 Oct;114(40):665-672

Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität of Berlin, and Berlin Institute of Health, Department of Psychiatry and Psychotherapy; Department of Psychiatry, University of British Columbia (UBC), Vancouver, Kanada; Psychiatric Clinic of the Ludwig-Maximilians-Universität München; Department of Psychiatry, Psychotherapy, and Psychosomatics, Psychiatric Hospital, University of Zürich.

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http://dx.doi.org/10.3238/arztebl.2017.0665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963583PMC
October 2017

How well do patients with a first episode of schizophrenia respond to antipsychotics: A systematic review and meta-analysis.

Eur Neuropsychopharmacol 2017 09 29;27(9):835-844. Epub 2017 Jun 29.

Department of Psychiatry and Psychotherapy, Technische Universität München, Klinikum rechts der Isar, Ismaningerstraße 22, 81675 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2017.06.011DOI Listing
September 2017

Antipsychotic drugs for the acute treatment of patients with a first episode of schizophrenia: a systematic review with pairwise and network meta-analyses.

Lancet Psychiatry 2017 09 20;4(9):694-705. Epub 2017 Jul 20.

Department of Psychiatry and Psychotherapy, Technische Universität München, Klinikum rechts der Isar, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/S2215-0366(17)30270-5DOI Listing
September 2017

Do antipsychotic drugs lose their efficacy for relapse prevention over time?

Br J Psychiatry 2017 Sep;211(3):127-129

Stefan Leucht, MD, Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Klinikum rechts der Isar, Munich, Germany; John M. Davis, MD, Psychiatric Institute, University of Illinois at Chicago, Chicago, Illinois and Maryland Psychiatric Research Center, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1192/bjp.bp.117.201103DOI Listing
September 2017

Common pitfalls and mistakes in the set-up, analysis and interpretation of results in network meta-analysis: what clinicians should look for in a published article.

Evid Based Ment Health 2017 08 24;20(3):88-94. Epub 2017 Jul 24.

Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.

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http://dx.doi.org/10.1136/eb-2017-102753DOI Listing
August 2017

Do antipsychotics lead to cognitive impairment in dementia? A meta-analysis of randomised placebo-controlled trials.

Eur Arch Psychiatry Clin Neurosci 2017 Apr 16;267(3):187-198. Epub 2016 Aug 16.

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Str. 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1007/s00406-016-0723-4DOI Listing
April 2017

Combining randomized and non-randomized evidence in network meta-analysis.

Stat Med 2017 04 12;36(8):1210-1226. Epub 2017 Jan 12.

Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece.

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http://dx.doi.org/10.1002/sim.7223DOI Listing
April 2017

Clozapine in treatment-resistant schizophrenia.

Br J Psychiatry 2017 04;210(4):299

Myrto Samara, MD, Department of Psychiatry and Psychotherapy, Technische Universität München, Munich, Germany. Email: Stefan Leucht, Professor, Department of Psychiatry and Psychotherapy, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1192/bjp.210.4.299DOI Listing
April 2017

Α Markov model for longitudinal studies with incomplete dichotomous outcomes.

Pharm Stat 2017 03 5;16(2):122-132. Epub 2016 Dec 5.

Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece.

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http://dx.doi.org/10.1002/pst.1794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363348PMC
March 2017

Schizophrenia, primary negative symptoms, and soft outcomes in psychiatry.

Lancet 2017 03 7;389(10074):1077-1078. Epub 2017 Feb 7.

Psychiatric Institute, University of Illinois at Chicago, Chicago, IL, USA; Maryland Psychiatric Research Center, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/S0140-6736(17)30181-2DOI Listing
March 2017

DSM-III-R change in definition might have affected placebo response to antidepressants - Authors' reply.

Lancet Psychiatry 2017 Jan;4(1):22-23

Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland; Department of Hygiene and Epidemiology, University of Ioannina, Ioannina, Greece.

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http://dx.doi.org/10.1016/S2215-0366(16)30415-1DOI Listing
January 2017

Identifying a system of predominant negative symptoms: Network analysis of three randomized clinical trials.

Schizophr Res 2016 12 9;178(1-3):17-22. Epub 2016 Sep 9.

Department of Psychiatry and Psychotherapy, Technische Universität München, Klinikum Rechts der Isar, Ismaningerstr. 22, 81675 Muenchen, Germany.

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http://dx.doi.org/10.1016/j.schres.2016.09.002DOI Listing
December 2016

Placebo response rates in antidepressant trials: a systematic review of published and unpublished double-blind randomised controlled studies.

Lancet Psychiatry 2016 Nov 7;3(11):1059-1066. Epub 2016 Oct 7.

Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland; Department of Hygiene and Epidemiology, University of Ioannina, Greece.

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http://dx.doi.org/10.1016/S2215-0366(16)30307-8DOI Listing
November 2016

Valproate for schizophrenia.

Cochrane Database Syst Rev 2016 11 24;11:CD004028. Epub 2016 Nov 24.

Neuro-Cognitive Psychology Master Program, Ludwig-Maximilians-Universität München, Thalkirchner Str. 9, Munich, Bavaria, Germany, D-80337.

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http://dx.doi.org/10.1002/14651858.CD004028.pub4DOI Listing
November 2016

The Longitudinal Course of Schizophrenia Across the Lifespan: Clinical, Cognitive, and Neurobiological Aspects.

Harv Rev Psychiatry 2016 Mar-Apr;24(2):118-28

From the Institute of Psychiatric Phenomics and Genomics (Drs. Heilbronner and Schulze, and Department of Psychiatry and Psychotherapy (Dr. Falkai), Ludwig-Maximilians-University Munich; Section on Psychiatric Genetics, Department of Psychiatry and Psychotherapy, University Medical Center Göttingen (Drs. Heilbronner and Schulze); Department of Psychiatry and Psychotherapy, Technical University Munich (Drs. Samara and Leucht).

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http://dx.doi.org/10.1097/HRP.0000000000000092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079232PMC
October 2016

Use of Clozapine in Schizophrenia-Reply.

JAMA Psychiatry 2016 10;73(10):1098-1099

Department of Psychiatry and Psychotherapy, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1001/jamapsychiatry.2016.1331DOI Listing
October 2016

The SWITCH study: rationale and design of the trial.

Eur Arch Psychiatry Clin Neurosci 2016 Sep 31;266(6):513-21. Epub 2015 Jul 31.

Klinik und Poliklinik fuer Psychiatrie und Psychotherapie, der Technischen Universitaet Muenchen, am Klinikum rechts der Isar, Ismaningerstrasse 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1007/s00406-015-0624-yDOI Listing
September 2016

Efficacy and Safety of Antidepressants Added to Antipsychotics for Schizophrenia: A Systematic Review and Meta-Analysis.

Am J Psychiatry 2016 Sep 10;173(9):876-86. Epub 2016 Jun 10.

From the Department of Psychiatry and Psychotherapy, Klinikum der Ludwig-Maximilians-Universität, Munich, Germany; and the Department of Psychiatry and Psychotherapy, Technische Universität München, Klinikum rechts der Isar, Munich, Germany.

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http://dx.doi.org/10.1176/appi.ajp.2016.15081035DOI Listing
September 2016

Network meta-analyses should be the highest level of evidence in treatment guidelines.

Eur Arch Psychiatry Clin Neurosci 2016 Sep;266(6):477-80

Institute of Social and Preventive Medicine (ISPM) and Berner Institut für Hausarztmedizin (BIHAM), University of Bern, Finkenhubelweg 11, 3012, Bern, Switzerland.

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http://dx.doi.org/10.1007/s00406-016-0715-4DOI Listing
September 2016

Second-generation antipsychotics and quality of life in schizophrenia.

Lancet Psychiatry 2016 08 2;3(8):694-695. Epub 2016 Jun 2.

Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1016/S2215-0366(16)30093-1DOI Listing
August 2016

Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.

Lancet 2016 Aug 8;388(10047):881-90. Epub 2016 Jun 8.

Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(16)30385-3DOI Listing
August 2016

Authors' reply.

Br J Psychiatry 2016 08;209(2):171-2

Aaron Prosser, MSc, Complex Mental Illness Program (Forensic Division), Centre for Addiction and Mental Health, Toronto, Canada, M6J 1H4. Tel: (416) 535-8501 ext. 32338; email: Bartosz Helfer, MSc, King's College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, UK; Stefan Leucht, MD, Department of Psychiatry and Psychotherapy, Technical University Munich, Klinikumrechts der Isar, Munich, Germany.

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http://dx.doi.org/10.1192/bjp.209.2.171bDOI Listing
August 2016

Dose Equivalents for Antipsychotic Drugs: The DDD Method.

Schizophr Bull 2016 07;42 Suppl 1:S90-4

Psychiatric Institute, University of Illinois at Chicago, Chicago, IL; Maryland Psychiatric Research Center, University of Maryland, Baltimore, MD.

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http://dx.doi.org/10.1093/schbul/sbv167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960429PMC
July 2016

Are all first-generation antipsychotics equally effective in treating schizophrenia? A meta-analysis of randomised, haloperidol-controlled trials.

World J Biol Psychiatry 2016 Apr 26;17(3):210-20. Epub 2016 Feb 26.

b Department of Psychiatry and Psychotherapy , Technische Universität München , München , Germany.

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http://dx.doi.org/10.3109/15622975.2015.1083616DOI Listing
April 2016

Biological v. psychosocial treatments: a myth about pharmacotherapy v. psychotherapy.

Br J Psychiatry 2016 Apr;208(4):309-11

Aaron Prosser, MSc, Complex Mental Illness Program (Forensic Division), Centre for Addiction and Mental Health, Toronto, Canada; Bartosz Helfer, MSc, King's College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, London, UK; Stefan Leucht, MD, Department of Psychiatry and Psychotherapy, Technical University Munich, Klinikum rechts der Isar, Munich, Germany.

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http://dx.doi.org/10.1192/bjp.bp.115.178368DOI Listing
April 2016

Using the contribution matrix to evaluate complex study limitations in a network meta-analysis: a case study of bipolar maintenance pharmacotherapy review.

BMC Res Notes 2016 Apr 14;9:218. Epub 2016 Apr 14.

Institute of Social and Preventive Medicine (ISPM) & Berner Institut für Hausarztmedizin (BIHAM), University of Bern, Finkenhubelweg 11, 3012, Bern, Switzerland.

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http://dx.doi.org/10.1186/s13104-016-2019-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831112PMC
April 2016

Efficacy, Acceptability, and Tolerability of Antipsychotics in Treatment-Resistant Schizophrenia: A Network Meta-analysis.

JAMA Psychiatry 2016 Mar;73(3):199-210

Department of Psychiatry and Psychotherapy, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1001/jamapsychiatry.2015.2955DOI Listing
March 2016

Publication bias and small-study effects magnified effectiveness of antipsychotics but their relative ranking remained invariant.

J Clin Epidemiol 2016 Jan 5;69:161-9. Epub 2015 Jun 5.

Department of Hygiene and Epidemiology, University of Ioannina, PO Box 1186, 45110 Ioannina, Greece.

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http://dx.doi.org/10.1016/j.jclinepi.2015.05.027DOI Listing
January 2016

Dose Equivalents for Second-Generation Antipsychotic Drugs: The Classical Mean Dose Method.

Schizophr Bull 2015 Nov 3;41(6):1397-402. Epub 2015 Apr 3.

Psychiatric Institute, University of Illinois at Chicago, Chicago, IL.

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http://dx.doi.org/10.1093/schbul/sbv037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601707PMC
November 2015

How effective are common medications: a perspective based on meta-analyses of major drugs.

BMC Med 2015 Oct 2;13:253. Epub 2015 Oct 2.

Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1186/s12916-015-0494-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592565PMC
October 2015

Lithium for schizophrenia.

Cochrane Database Syst Rev 2015 Oct 28(10):CD003834. Epub 2015 Oct 28.

Klinik und Poliklinik für Psychiatrie und Psychotherapie, Technische Universität München Klinikum rechts der Isar, Ismaninger Straße 22, München, Germany, 81675.

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http://dx.doi.org/10.1002/14651858.CD003834.pub3DOI Listing
October 2015

Dose equivalents of antidepressants: Evidence-based recommendations from randomized controlled trials.

J Affect Disord 2015 Jul 31;180:179-84. Epub 2015 Mar 31.

Department of Health Promotion and Human Behavior, Kyoto University Graduate School of Medicine/School of Public Health, Yoshida Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1016/j.jad.2015.03.021DOI Listing
July 2015

Early Improvement As a Predictor of Later Response to Antipsychotics in Schizophrenia: A Diagnostic Test Review.

Am J Psychiatry 2015 Jul 5;172(7):617-29. Epub 2015 Jun 5.

From the Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, the Netherlands; Dr. Kurt Fontheim's Hospital for Mental Health, Liebenburg, Germany; Chonbuk National University Medical School, Jeonju, Korea; the Department of Psychiatry, Marqués de Valdecilla University Hospital-IDIVAL, School of Medicine, University of Cantabria, Santander, Spain; CIBERSAM (Centro Investigación Biomédica en Red Salud Mental), Madrid; the Department and Institute of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil; the Department of Psychiatry, Juntendo University Nerima Hospital, Tokyo; the Department of Psychiatry, Ludwig-Maximilians University, Munich; the Department of Psychiatry, University of Halle-Wittenberg, Halle, Germany; Hofstra North Shore Long Island Jewish School of Medicine, Hempstead, N.Y.; the Zucker Hillside Hospital, Glen Oaks, N.Y.; the Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Kaohsiung Municipal Kai-Syuan Psychiatric Hospital, Kaohsiung, Taiwan; the Department of Psychiatry, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; University Hospital of Child and Adolescent Psychiatry, University of Bern, Bern, Switzerland; and the Department of Biomedical and NeuroMotor Sciences, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.1176/appi.ajp.2015.14101329DOI Listing
July 2015

Modeling determinants of medication attitudes and poor adherence in early nonaffective psychosis: implications for intervention.

Schizophr Bull 2015 May 5;41(3):584-96. Epub 2015 Mar 5.

Manchester Academic Health Sciences Centre, Institute of Brain, Behaviour & Mental Health, University of Manchester, Manchester, UK; Manchester Academic Health Sciences Centre, Manchester Mental Health & Social Care NHS Trust, Manchester, UK;

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http://dx.doi.org/10.1093/schbul/sbv015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393703PMC
May 2015

Joint modeling of dropout and outcome in three pivotal clinical trials of schizophrenia.

Schizophr Res 2015 May 16;164(1-3):122-6. Epub 2015 Mar 16.

Department of Psychiatry and Psychotherapy, Technische Universität München, Germany.

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http://dx.doi.org/10.1016/j.schres.2015.02.021DOI Listing
May 2015

CYP1A2*1D and *1F polymorphisms have a significant impact on olanzapine serum concentrations.

Ther Drug Monit 2015 Apr;37(2):152-60

*Institut für Klinische Chemie und Pathobiochemie; and †Klinik und Poliklinik für Psychiatrie und Psychotherapie, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/FTD.0000000000000119DOI Listing
April 2015

Recent meta-analyses neglect previous systematic reviews and meta-analyses about the same topic: a systematic examination.

BMC Med 2015 Apr 14;13:82. Epub 2015 Apr 14.

Department of Psychiatry and Psychotherapy, Technical University Munich, Klinikum rechts der Isar, Ismaningerstr 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1186/s12916-015-0317-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411715PMC
April 2015

Perphenazine for schizophrenia.

Cochrane Database Syst Rev 2015 Mar 6(3):CD003443. Epub 2015 Mar 6.

Institute for Legal Medicine, University Hospital Düsseldorf, Moorenstr. 5, Düsseldorf, North Rhine Westphalia, Germany, 40225.

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http://dx.doi.org/10.1002/14651858.CD003443.pub3DOI Listing
March 2015

Accounting for uncertainty due to 'last observation carried forward' outcome imputation in a meta-analysis model.

Stat Med 2015 Feb 10;34(5):742-52. Epub 2014 Dec 10.

Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece.

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http://dx.doi.org/10.1002/sim.6364DOI Listing
February 2015

Initial severity of schizophrenia and efficacy of antipsychotics: participant-level meta-analysis of 6 placebo-controlled studies.

JAMA Psychiatry 2015 Jan;72(1):14-21

Department of Psychiatry and Psychotherapy, Technische Universität München, München, Germany9Department of Psychiatry, University of Oxford, Oxford, United Kingdom10Institute of Psychiatry, King's College London, London, United Kingdom.

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http://yoda.yale.edu/sites/default/files/initial_severity_ja
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http://dx.doi.org/10.1001/jamapsychiatry.2014.2127DOI Listing
January 2015

Haloperidol versus first-generation antipsychotics for the treatment of schizophrenia and other psychotic disorders.

Cochrane Database Syst Rev 2015 Jan 16;1:CD009831. Epub 2015 Jan 16.

Klinik und Poliklinik für Psychiatrie und Psychotherapie, Technische Universität München Klinikum rechts der Isar, Ismaninger Straße 22, München, Germany, 81675.

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http://dx.doi.org/10.1002/14651858.CD009831.pub2DOI Listing
January 2015

Equipercentile linking of scales measuring functioning and symptoms: examining the GAF, SOFAS, CGI-S, and PANSS.

Eur Neuropsychopharmacol 2014 Nov 20;24(11):1767-72. Epub 2014 Aug 20.

Department of Psychiatry and Psychotherapy, Technische Universität München, Klinikum rechts der Isar, Ismaningerstr. 22, 81675 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2014.08.009DOI Listing
November 2014

Bipolar treatment efficacy - Authors' reply.

Lancet Psychiatry 2014 Nov 5;1(6):418-9. Epub 2014 Nov 5.

Department of Neuropsychiatry Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1016/S2215-0366(14)00011-XDOI Listing
November 2014

Perphenazine versus low-potency first-generation antipsychotic drugs for schizophrenia.

Cochrane Database Syst Rev 2014 Oct 7(10):CD009369. Epub 2014 Oct 7.

Klinik und Poliklinik für Psychiatrie und Psychotherapie, Technische Universität München Klinikum rechts der Isar, Möhlstr. 26, München, Germany, 81675.

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http://dx.doi.org/10.1002/14651858.CD009369.pub2DOI Listing
October 2014

Flupenthixol versus low-potency first-generation antipsychotic drugs for schizophrenia.

Cochrane Database Syst Rev 2014 Sep 1(9):CD009227. Epub 2014 Sep 1.

Klinik und Poliklinik für Psychiatrie und Psychotherapie, Technische Universität München Klinikum rechts der Isar, Möhlstr. 26, München, Germany, 81675.

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http://dx.doi.org/10.1002/14651858.CD009227.pub2DOI Listing
September 2014